{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:31:43Z","timestamp":1790271103756,"version":"4.1.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T00:00:00Z","timestamp":1525651200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Provincial Grand Lodge of Bedfordshire"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1007\/s10549-018-4788-9","type":"journal-article","created":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T15:55:55Z","timestamp":1525708555000},"page":"103-110","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["A double-blind, randomised trial of a polyphenolic-rich nail bed balm for chemotherapy-induced onycholysis: the UK polybalm study"],"prefix":"10.1007","volume":"171","author":[{"given":"Robert","family":"Thomas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeleine","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Cauchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saul","family":"Berkovitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,5,7]]},"reference":[{"key":"4788_CR1","unstructured":"Macmillan (2018) Caring for skin and nails. \n                    https:\/\/www.macmillan.org.uk\/information-and-support\/coping\/changes-to-appearance-and-body-image\/changes-during-treatment\/caring-for-skin-and-nails.html\n                    \n                  . Accessed Mar 2018"},{"key":"4788_CR2","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.clindermatol.2013.06.013","volume":"31","author":"BM Piraccini","year":"2013","unstructured":"Piraccini BM, Alessandrini A (2013) Drug-related nail disease. Clin Dermatol 31:618\u2013626","journal-title":"Clin Dermatol"},{"key":"4788_CR3","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1093\/annonc\/mdg050","volume":"14","author":"AM Minisini","year":"2003","unstructured":"Minisini AM, Tosti A, Sobrero AF et al (2003) Taxane-induced nail changes: incidence, clinical presentation and outcome. Ann Oncol 14:333\u2013337","journal-title":"Ann Oncol"},{"key":"4788_CR4","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/BF00192885","volume":"73","author":"EJ Battegay","year":"1995","unstructured":"Battegay EJ (1995) Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects. J Mol Med 73:333\u2013346","journal-title":"J Mol Med"},{"key":"4788_CR5","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1023\/A:1016002329546","volume":"58","author":"G Wasner","year":"2002","unstructured":"Wasner G, Hilpert F, Schattschneider J et al (2002) Docetaxel-induced nail changes: a neurogenic mechanism\u2014a case report. J Neurooncol 58:167\u2013174","journal-title":"J Neurooncol"},{"issue":"7953","key":"4788_CR6","doi-asserted-by":"publisher","first-page":"2732","DOI":"10.1136\/bmj.g1800","volume":"348","author":"S Eisman","year":"2014","unstructured":"Eisman S, Sinclair R (2014) Fungal nail infection: diagnosis and management. BMJ 348(7953):27\u201332. \n                    https:\/\/doi.org\/10.1136\/bmj.g1800","journal-title":"BMJ"},{"issue":"1","key":"4788_CR7","first-page":"18","volume":"2","author":"PN Ding","year":"2010","unstructured":"Ding PN, Thomas RJ (2010) A cool solution for docetaxel induced onycholysis. Focus Cancer Med 2(1):18\u201319","journal-title":"Focus Cancer Med"},{"issue":"19","key":"4788_CR8","doi-asserted-by":"publisher","first-page":"4424","DOI":"10.1200\/JCO.2005.15.651","volume":"23","author":"F Scott\u00e9","year":"2005","unstructured":"Scott\u00e9 F, Tourani J-M, Banu E et al (2005) Multicenter study of a frozen glove to prevent docetaxel-induced onycholysis and cutaneous toxicity of the hand. J Clin Oncol 23(19):4424\u20134429","journal-title":"J Clin Oncol"},{"key":"4788_CR9","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.1007\/s00520-011-1308-4","volume":"20","author":"H Ishiguro","year":"2012","unstructured":"Ishiguro H, Takashima D, Yoshimura K et al (2012) Degree of freezing does not affect efficacy of frozen gloves for prevention of docetaxel-induced nail toxicity in breast cancer patients. Support Care Cancer 20:2017\u20132024","journal-title":"Support Care Cancer"},{"issue":"1\u20132","key":"4788_CR10","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/S0168-1605(01)00734-6","volume":"74","author":"PJ Delaquis","year":"2002","unstructured":"Delaquis PJ, Stanich K, Girard B (2002) Antimicrobial activity of individual of essential oils. Int J Food Microbiol 74(1\u20132):101\u2013109","journal-title":"Int J Food Microbiol"},{"issue":"3","key":"4788_CR11","first-page":"170","volume":"30","author":"R Dawid-Pa\u0107","year":"2013","unstructured":"Dawid-Pa\u0107 R (2013) Medicinal plants used in treatment of inflammatory skin diseases. Postepy Dermatol Alerqol 30(3):170\u2013177","journal-title":"Postepy Dermatol Alerqol"},{"issue":"2","key":"4788_CR12","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1046\/j.1472-765X.1998.00303.x","volume":"26","author":"A Smith-Palmer","year":"2002","unstructured":"Smith-Palmer A, Stewart B, Fyfe C (2002) Antimicrobial properties of plant essential oils and essences against five important food-borne pathogens. Lett Appl Microbiol 26(2):118\u2013122","journal-title":"Lett Appl Microbiol"},{"issue":"10","key":"4788_CR13","doi-asserted-by":"publisher","first-page":"164","DOI":"10.4103\/0973-7847.91114","volume":"5","author":"RR Kora\u0107","year":"2011","unstructured":"Kora\u0107 RR, Khambholja KM (2011) Herbs protect cells from UV radiation. Pharmacogn Rev 5(10):164\u2013173","journal-title":"Pharmacogn Rev"},{"key":"4788_CR14","doi-asserted-by":"publisher","first-page":"912028","DOI":"10.1155\/2012\/912028","volume":"2012","author":"M-Q Man","year":"2012","unstructured":"Man M-Q, Hupe M, Sun R et al (2012) Topical apigenin alleviates cutaneous inflammation in murine models. Evid Based Complement Altern Med 2012:912028. \n                    https:\/\/doi.org\/10.1155\/2012\/912028","journal-title":"Evid Based Complement Altern Med"},{"key":"4788_CR15","doi-asserted-by":"publisher","first-page":"S45","DOI":"10.1016\/S0923-1811(00)00083-9","volume":"23","author":"M Ichihashi","year":"2000","unstructured":"Ichihashi M, Ahmed NU, Budiyanto A et al (2000) Preventive effect of antioxidant on ultraviolet-induced skin cancer in mice. J Dermatol Sci 23:S45\u2013S50","journal-title":"J Dermatol Sci"},{"issue":"4","key":"4788_CR16","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1002\/(SICI)1099-1026(1998070)13:4<235::AID-FFJ733>3.0.CO;2-T","volume":"13","author":"MT Tiziana Baratta","year":"2001","unstructured":"Tiziana Baratta MT, Damien Dorman HJ, Deans SG et al (2001) Antimicrobial and antioxidant properties of some commercial essential oils. Flavour Fragr J 13(4):235\u2013244","journal-title":"Flavour Fragr J"},{"issue":"2","key":"4788_CR17","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1039\/B505311K","volume":"5","author":"MS Baliga","year":"2006","unstructured":"Baliga MS, Katiyar SK (2006) Chemoprevention of photocarcinogenesis by selected dietary botanicals. Photochem Photobiol Sci 5(2):243\u2013253","journal-title":"Photochem Photobiol Sci"},{"issue":"1\u20133","key":"4788_CR18","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1385\/BTER:82:1-3:201","volume":"82","author":"C Milin","year":"2001","unstructured":"Milin C, Domitrovi\u0107 R, Tota J et al (2001) Effect of olive oil and corn oil enriched diets on the tissue mineral content in mice. Biol Trace Elem Res 82(1\u20133):201\u2013210","journal-title":"Biol Trace Elem Res"},{"key":"4788_CR19","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1111\/j.1600-0536.2006.00801.x","volume":"55","author":"CD Jensen","year":"1999","unstructured":"Jensen CD, Andersen KE (1999) Allergic contact dermatitis from cera alba (purified propolis) in a balms. Contact Dermatitis 55:312\u2013313","journal-title":"Contact Dermatitis"},{"issue":"14","key":"4788_CR20","first-page":"1200","volume":"11","author":"F Afaq","year":"2011","unstructured":"Afaq F, Katiyar SK (2011) Polyphenols: skin photoprotection and inhibition of photocarcinogenesis. Mini Rev Med Chem 11(14):1200\u20131125","journal-title":"Mini Rev Med Chem"},{"key":"4788_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/nu8010017","author":"Y Kim","year":"2016","unstructured":"Kim Y, Keogh JB, Clifton PM (2016) Polyphenols and glycemic control. Nutrients. \n                    https:\/\/doi.org\/10.3390\/nu8010017","journal-title":"Nutrients"},{"key":"4788_CR22","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1038\/pcan.2014.6","volume":"17","author":"R Thomas","year":"2014","unstructured":"Thomas R, Williams M, Sharma H et al (2014) A double-blind placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer the UK National Cancer Research Network (NCRN) Pomi-T study. Prostate Cancer Prostatic Dis 17:180\u2013186","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"4788_CR23","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1136\/bjsports-2016-096343","volume":"51","author":"R Thomas","year":"2017","unstructured":"Thomas R, Stacey K, Jimenez A (2017) Exercise-induced biochemical changes and their potential influence on cancer: a scientific review. Br J Sports Med 51:640\u2013644","journal-title":"Br J Sports Med"},{"issue":"1","key":"4788_CR24","first-page":"36","volume":"2","author":"AF Stallings","year":"2009","unstructured":"Stallings AF, Lupo M (2009) Practical uses of botanicals in skin care. J Clin Aesthet Dermatol 2(1):36\u201340","journal-title":"J Clin Aesthet Dermatol"},{"key":"4788_CR25","first-page":"330","volume-title":"Herbal medicine: expanded commission e monographs","author":"M Blumenthal","year":"2000","unstructured":"Blumenthal M, Goldberg A, Brinckmann J (2000) Herbal medicine: expanded commission e monographs. Integrative Medicine Communications, Boston, pp\u00a0330\u2013333"},{"key":"4788_CR26","first-page":"33362","volume":"68","author":"Food and Drug Administration HaHS","year":"2003","unstructured":"Food and Drug Administration HaHS (2003) Skin protectant drug products for over-the-counter human use; final monograph: final rule. Fed Reg 68:33362\u201333381","journal-title":"Fed Reg"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10549-018-4788-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-018-4788-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-018-4788-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T17:10:02Z","timestamp":1557421802000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10549-018-4788-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,7]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["4788"],"URL":"https:\/\/doi.org\/10.1007\/s10549-018-4788-9","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,7]]},"assertion":[{"value":"4 April 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}