{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:13:57Z","timestamp":1793330037863,"version":"4.5.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,7,20]],"date-time":"2018-07-20T00:00:00Z","timestamp":1532044800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1007\/s10549-018-4898-4","type":"journal-article","created":{"date-parts":[[2018,7,20]],"date-time":"2018-07-20T10:03:55Z","timestamp":1532081035000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Occult breast cancer may originate from ectopic breast tissue present in axillary lymph nodes"],"prefix":"10.1007","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1304-2619","authenticated-orcid":false,"given":"Mitsuo","family":"Terada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yayoi","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Sawaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiyo","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gondo","family":"Naomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruru","family":"Kotani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madoka","family":"Iwase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayumi","family":"Kataoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakura","family":"Onishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayoko","family":"Sugino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makiko","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanae","family":"Horisawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiichi","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Yatabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroji","family":"Iwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,7,20]]},"reference":[{"key":"4898_CR1","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1001\/archsurg.1990.01410140088014","volume":"125","author":"PL Baron","year":"1990","unstructured":"Baron PL, Moore MP, Kinne DW et al (1990) Occult breast cancer presenting with axillary metastases. Updated management. Arch Surg 125:210\u2013214","journal-title":"Arch Surg"},{"key":"4898_CR2","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s10549-004-9453-9","volume":"88","author":"V Galimberti","year":"2004","unstructured":"Galimberti V, Bassani G, Monti S et al (2004) Clinical experience with axillary presentation breast cancer. Breast Cancer Res Treat 88:43\u201347. \n                    https:\/\/doi.org\/10.1007\/s10549-004-9453-9","journal-title":"Breast Cancer Res Treat"},{"key":"4898_CR3","doi-asserted-by":"publisher","first-page":"2923","DOI":"10.1002\/1097-0142(19810615)47:12<2923::AID-CNCR2820471231>3.0.CO;2-N","volume":"47","author":"J Patel","year":"1981","unstructured":"Patel J, Nemoto T, Rosner D et al (1981) Axillary lymph node metastasis from an occult breast cancer. Cancer 47:2923\u20132927","journal-title":"Cancer"},{"key":"4898_CR4","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1016\/0046-8177(90)90008-S","volume":"21","author":"PP Rosen","year":"1990","unstructured":"Rosen PP, Kimmel M (1990) Occult breast carcinoma presenting with axillary lymph node metastases: a follow-up study of 48 patients. Hum Pathol 21:518\u2013523","journal-title":"Hum Pathol"},{"key":"4898_CR5","doi-asserted-by":"publisher","first-page":"4000","DOI":"10.1002\/cncr.25197","volume":"116","author":"GV Walker","year":"2010","unstructured":"Walker GV, Smith GL, Perkins GH et al (2010) Population-based analysis of occult primary breast cancer with axillary lymph node metastasis. Cancer 116:4000\u20134006. \n                    https:\/\/doi.org\/10.1002\/cncr.25197","journal-title":"Cancer"},{"key":"4898_CR6","doi-asserted-by":"publisher","first-page":"425","DOI":"10.2325\/jbcs.14.425","volume":"14","author":"M Kadowaki","year":"2007","unstructured":"Kadowaki M, Nagashima T, Sakata H et al (2007) Ectopic breast tissue in axillary lymph node. Breast Cancer 14:425\u2013428. \n                    https:\/\/doi.org\/10.2325\/jbcs.14.425","journal-title":"Breast Cancer"},{"key":"4898_CR7","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1093\/ajcp\/59.5.666","volume":"59","author":"DW Edlow","year":"1973","unstructured":"Edlow DW, Carter D (1973) Heterotopic epithelium in axillary lymph nodes: report of a case and review of the literature. Am J Clin Pathol 59:666\u2013673","journal-title":"Am J Clin Pathol"},{"key":"4898_CR8","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1111\/j.1365-2559.1980.tb02958.x","volume":"4","author":"DR Turner","year":"1980","unstructured":"Turner DR, Millis RR (1980) Breast tissue inclusions in axillary lymph nodes. Histopathology 4:631\u2013636","journal-title":"Histopathology"},{"key":"4898_CR9","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1097\/00000478-200304000-00012","volume":"27","author":"E Maiorano","year":"2003","unstructured":"Maiorano E, Mazzarol GM, Pruneri G et al (2003) Ectopic breast tissue as a possible cause of false-positive axillary sentinel lymph node biopsies. Am J Surg Pathol 27:513\u2013518","journal-title":"Am J Surg Pathol"},{"key":"4898_CR10","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1111\/j.1365-2559.2005.02233.x","volume":"48","author":"L Migliorini","year":"2006","unstructured":"Migliorini L (2006) Proliferative intraductal lesion arising in ectopic breast tissue within axillary lymph node. Histopathology 48:316\u2013317. \n                    https:\/\/doi.org\/10.1111\/j.1365-2559.2005.02233.x","journal-title":"Histopathology"},{"key":"4898_CR11","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1186\/1752-1947-8-162","volume":"8","author":"H Cottom","year":"2014","unstructured":"Cottom H, Rengabashyam B, Turton PE, Shaaban AM (2014) Intraductal papilloma in an axillary lymph node of a patient with human immunodeficiency virus: a case report and review of the literature. J Med Case Rep 8:162. \n                    https:\/\/doi.org\/10.1186\/1752-1947-8-162","journal-title":"J Med Case Rep"},{"key":"4898_CR12","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1016\/j.ejso.2012.08.022","volume":"38","author":"M He","year":"2012","unstructured":"He M, Tang L-C, Yu K-D et al (2012) Treatment outcomes and unfavorable prognostic factors in patients with occult breast cancer. Eur J Surg Oncol 38:1022\u20131028","journal-title":"Eur J Surg Oncol"},{"key":"4898_CR13","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1245\/s10434-014-3991-0","volume":"22","author":"NM Rueth","year":"2015","unstructured":"Rueth NM, Black DM, Limmer AR et al (2015) Breast conservation in the setting of contemporary multimodality treatment provides excellent outcomes for patients with occult primary breast cancer. Ann Surg Oncol 22:90\u201395. \n                    https:\/\/doi.org\/10.1245\/s10434-014-3991-0","journal-title":"Ann Surg Oncol"},{"key":"4898_CR14","doi-asserted-by":"publisher","first-page":"3141","DOI":"10.1245\/s10434-017-5965-5","volume":"24","author":"DP McCartan","year":"2017","unstructured":"McCartan DP, Zabor EC, Morrow M et al (2017) Oncologic outcomes after treatment for MRI occult breast cancer (pT0N+). Ann Surg Oncol 24:3141\u20133147. \n                    https:\/\/doi.org\/10.1245\/s10434-017-5965-5","journal-title":"Ann Surg Oncol"},{"key":"4898_CR15","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1007\/s00268-004-7290-y","volume":"28","author":"DK Blanchard","year":"2004","unstructured":"Blanchard DK, Farley DR (2004) Retrospective study of women presenting with axillary metastases from occult breast carcinoma. World J Surg 28:535\u2013539","journal-title":"World J Surg"},{"key":"4898_CR16","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1007\/s10434-001-0425-6","volume":"8","author":"G Vlastos","year":"2001","unstructured":"Vlastos G, Jean ME, Mirza AN et al (2001) Feasibility of breast preservation in the treatment of occult primary carcinoma presenting with axillary metastases. Ann Surg Oncol 8:425\u2013431","journal-title":"Ann Surg Oncol"},{"key":"4898_CR17","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1111\/j.1524-4741.2009.00848.x","volume":"16","author":"X Wang","year":"2010","unstructured":"Wang X, Zhao Y, Cao X (2010) Clinical benefits of mastectomy on treatment of occult breast carcinoma presenting axillary metastases. Breast J 16:32\u201337. \n                    https:\/\/doi.org\/10.1111\/j.1524-4741.2009.00848.x","journal-title":"Breast J"},{"key":"4898_CR18","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1002\/1097-0142(19901001)66:7<1461::AID-CNCR2820660704>3.0.CO;2-Z","volume":"66","author":"N Ellerbroek","year":"1990","unstructured":"Ellerbroek N, Holmes F, Singletary E et al (1990) Treatment of patients with isolated axillary nodal metastases from an occult primary carcinoma consistent with breast origin. Cancer 66:1461\u20131467","journal-title":"Cancer"},{"key":"4898_CR19","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1002\/1097-0142(19920715)70:2<504::AID-CNCR2820700221>3.0.CO;2-T","volume":"70","author":"M Merson","year":"1992","unstructured":"Merson M, Andreola S, Galimberti V et al (1992) Breast carcinoma presenting as axillary metastases without evidence of a primary tumor. Cancer 70:504\u2013508","journal-title":"Cancer"},{"key":"4898_CR20","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1002\/bjs.1800801026","volume":"80","author":"B Ooijen van","year":"1993","unstructured":"van Ooijen B, Bontenbal M, Henzen-Logmans SC, Koper PC (1993) Axillary nodal metastases from an occult primary consistent with breast carcinoma. Br J Surg 80:1299\u20131300","journal-title":"Br J Surg"},{"key":"4898_CR21","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/S0360-3016(99)00542-8","volume":"47","author":"F Foroudi","year":"2000","unstructured":"Foroudi F, Tiver KW (2000) Occult breast carcinoma presenting as axillary metastases. Int J Radiat Oncol Biol Phys 47:143\u2013147","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"4898_CR22","unstructured":"NCCN Clinical Practice Guidelines in Oncology. \n                    https:\/\/www.nccn.org\/professionals\/physician_gls\/default.aspx#occult\n                    \n                  . Accessed 23 Nov 2017"},{"key":"4898_CR23","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1148\/radiology.212.2.r99au40543","volume":"212","author":"SG Orel","year":"1999","unstructured":"Orel SG, Weinstein SP, Schnall MD et al (1999) Breast MR imaging in patients with axillary node metastases and unknown primary malignancy. Radiology 212:543\u2013549. \n                    https:\/\/doi.org\/10.1148\/radiology.212.2.r99au40543","journal-title":"Radiology"},{"key":"4898_CR24","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.ejso.2009.09.007","volume":"36","author":"J Bresser de","year":"2010","unstructured":"de Bresser J, de Vos B, van der Ent F, Hulsew\u00e9 K (2010) Breast MRI in clinically and mammographically occult breast cancer presenting with an axillary metastasis: a systematic review. Eur J Surg Oncol 36:114\u2013119","journal-title":"Eur J Surg Oncol"},{"key":"4898_CR25","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2463\/mrms.6.21","volume":"6","author":"S Kuroki-Suzuki","year":"2007","unstructured":"Kuroki-Suzuki S, Kuroki Y, Nasu K et al (2007) Detecting breast cancer with non-contrast MR imaging: combining diffusion-weighted and STIR imaging. Magn Reson Med Sci 6:21\u201327","journal-title":"Magn Reson Med Sci"},{"key":"4898_CR26","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/bcr271","volume":"3","author":"S Malur","year":"2001","unstructured":"Malur S, Wurdinger S, Moritz A et al (2001) Comparison of written reports of mammography, sonography and magnetic resonance mammography for preoperative evaluation of breast lesions, with special emphasis on magnetic resonance mammography. Breast Cancer Res BCR 3:55\u201360","journal-title":"Breast Cancer Res BCR"},{"key":"4898_CR27","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/1746-1596-5-17","volume":"5","author":"R Dzodic","year":"2010","unstructured":"Dzodic R, Stanojevic B, Saenko V et al (2010) Intraductal papilloma of ectopic breast tissue in axillary lymph node of a patient with a previous intraductal papilloma of ipsilateral breast: a case report and review of the literature. Diagn Pathol 5:17. \n                    https:\/\/doi.org\/10.1186\/1746-1596-5-17","journal-title":"Diagn Pathol"},{"key":"4898_CR28","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1007\/s10549-011-1923-2","volume":"132","author":"S Iken","year":"2012","unstructured":"Iken S, Schmidt M, Braun C et al (2012) Absence of ectopic epithelial inclusions in 3,904 axillary lymph nodes examined in sentinel technique. Breast Cancer Res Treat 132:621\u2013624. \n                    https:\/\/doi.org\/10.1007\/s10549-011-1923-2","journal-title":"Breast Cancer Res Treat"},{"key":"4898_CR29","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1097\/PAS.0b013e3182237985","volume":"35","author":"G Fellegara","year":"2011","unstructured":"Fellegara G, Carcangiu ML, Rosai J (2011) Benign epithelial inclusions in axillary lymph nodes: report of 18 cases and review of the literature. Am J Surg Pathol 35:1123\u20131133. \n                    https:\/\/doi.org\/10.1097\/PAS.0b013e3182237985","journal-title":"Am J Surg Pathol"},{"key":"4898_CR30","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1002\/jso.23644","volume":"110","author":"G Sohn","year":"2014","unstructured":"Sohn G, Son BH, Lee SJ et al (2014) Treatment and survival of patients with occult breast cancer with axillary lymph node metastasis: a nationwide retrospective study. J Surg Oncol 110:270\u2013274. \n                    https:\/\/doi.org\/10.1002\/jso.23644","journal-title":"J Surg Oncol"},{"key":"4898_CR31","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1007\/s10549-011-1697-6","volume":"129","author":"E Montagna","year":"2011","unstructured":"Montagna E, Bagnardi V, Rotmensz N et al (2011) Immunohistochemically defined subtypes and outcome in occult breast carcinoma with axillary presentation. Breast Cancer Res Treat 129:867\u2013875. \n                    https:\/\/doi.org\/10.1007\/s10549-011-1697-6","journal-title":"Breast Cancer Res Treat"},{"key":"4898_CR32","doi-asserted-by":"publisher","first-page":"2931","DOI":"10.1200\/JCO.2008.16.7619","volume":"27","author":"H Wildiers","year":"2009","unstructured":"Wildiers H, Van Calster B, van de Poll-Franse LV et al (2009) Relationship between age and axillary lymph node involvement in women with breast cancer. J Clin Oncol 27:2931\u20132937. \n                    https:\/\/doi.org\/10.1200\/JCO.2008.16.7619","journal-title":"J Clin Oncol"},{"key":"4898_CR33","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1007\/s10549-014-3225-y","volume":"149","author":"EV Holm-Rasmussen","year":"2015","unstructured":"Holm-Rasmussen EV, Jensen M-B, Balslev E et al (2015) Reduced risk of axillary lymphatic spread in triple-negative breast cancer. Breast Cancer Res Treat 149:229\u2013236. \n                    https:\/\/doi.org\/10.1007\/s10549-014-3225-y","journal-title":"Breast Cancer Res Treat"},{"key":"4898_CR34","doi-asserted-by":"publisher","first-page":"3780","DOI":"10.1245\/s10434-014-3851-y","volume":"21","author":"S Ugras","year":"2014","unstructured":"Ugras S, Stempel M, Patil S, Morrow M (2014) Estrogen receptor, progesterone receptor, and HER2 status predict lymphovascular invasion and lymph node involvement. Ann Surg Oncol 21:3780\u20133786. \n                    https:\/\/doi.org\/10.1245\/s10434-014-3851-y","journal-title":"Ann Surg Oncol"},{"key":"4898_CR35","doi-asserted-by":"publisher","first-page":"143","DOI":"10.4048\/jbc.2015.18.2.143","volume":"18","author":"MD Mattes","year":"2015","unstructured":"Mattes MD, Bhatia JK, Metzger D et al (2015) Breast cancer subtype as a predictor of lymph node metastasis according to the SEER registry. J Breast Cancer 18:143\u2013148. \n                    https:\/\/doi.org\/10.4048\/jbc.2015.18.2.143","journal-title":"J Breast Cancer"},{"key":"4898_CR36","doi-asserted-by":"publisher","first-page":"e2213","DOI":"10.1097\/MD.0000000000002213","volume":"94","author":"Z-Y He","year":"2015","unstructured":"He Z-Y, Wu S-G, Yang Q et al (2015) Breast cancer subtype is associated with axillary lymph node metastasis: a retrospective cohort study. Medicine (Baltimore) 94:e2213. \n                    https:\/\/doi.org\/10.1097\/MD.0000000000002213","journal-title":"Medicine (Baltimore)"},{"key":"4898_CR37","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s10549-006-9300-2","volume":"101","author":"MR D\u2019Andrea","year":"2007","unstructured":"D\u2019Andrea MR, Limiti MR, Bari M et al (2007) Correlation between genetic and biological aspects in primary non-metastatic breast cancers and corresponding synchronous axillary lymph node metastasis. Breast Cancer Res Treat 101:279\u2013284. \n                    https:\/\/doi.org\/10.1007\/s10549-006-9300-2","journal-title":"Breast Cancer Res Treat"},{"key":"4898_CR38","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1111\/j.1742-1241.2005.00546.x","volume":"59","author":"E Dikicioglu","year":"2005","unstructured":"Dikicioglu E, Barutca S, Meydan N, Meteoglu I (2005) Biological characteristics of breast cancer at the primary tumour and the involved lymph nodes. Int J Clin Pract 59:1039\u20131044. \n                    https:\/\/doi.org\/10.1111\/j.1742-1241.2005.00546.x","journal-title":"Int J Clin Pract"},{"key":"4898_CR39","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1002\/jso.10243","volume":"83","author":"C Iguchi","year":"2003","unstructured":"Iguchi C, Nio Y, Itakura M (2003) Heterogeneic expression of estrogen receptor between the primary tumor and the corresponding involved lymph nodes in patients with node-positive breast cancer and its implications in patient outcome. J Surg Oncol 83:85\u201393. \n                    https:\/\/doi.org\/10.1002\/jso.10243","journal-title":"J Surg Oncol"},{"key":"4898_CR40","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1002\/ijc.2910630607","volume":"63","author":"T Agthoven van","year":"1995","unstructured":"van Agthoven T, Timmermans M, Dorssers LC, Henzen-Logmans SC (1995) Expression of estrogen, progesterone and epidermal growth factor receptors in primary and metastatic breast cancer. Int J Cancer 63:790\u2013793","journal-title":"Int J Cancer"},{"key":"4898_CR41","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1002\/1097-0142(19910801)68:3<532::AID-CNCR2820680314>3.0.CO;2-G","volume":"68","author":"T Mori","year":"1991","unstructured":"Mori T, Morimoto T, Komaki K, Monden Y (1991) Comparison of estrogen receptor and epidermal growth factor receptor content of primary and involved nodes in human breast cancer. Cancer 68:532\u2013537","journal-title":"Cancer"},{"key":"4898_CR42","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1016\/S0344-0338(89)80286-9","volume":"185","author":"B Brunn Rasmussen","year":"1989","unstructured":"Brunn Rasmussen B, Kamby C (1989) Immunohistochemical detection of estrogen receptors in paraffin sections from primary and metastatic breast cancer. Pathol Res Pract 185:856\u2013859","journal-title":"Pathol Res Pract"},{"key":"4898_CR43","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1177\/030089168407000210","volume":"70","author":"D Coradini","year":"1984","unstructured":"Coradini D, Cappelletti V, Miodini P et al (1984) Distribution of estrogen and progesterone receptors in primary tumor and lymph nodes in individual patients with breast cancer. Tumori 70:165\u2013168","journal-title":"Tumori"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10549-018-4898-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-018-4898-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-018-4898-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T19:08:20Z","timestamp":1563563300000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10549-018-4898-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,20]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["4898"],"URL":"https:\/\/doi.org\/10.1007\/s10549-018-4898-4","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,20]]},"assertion":[{"value":"1 March 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 July 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed involving human participants were in accordance with the ethical standards of the Institutional Review Board of Aichi Cancer Center Hospital and with the 1964 Helsinki declaration and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}