{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T15:02:37Z","timestamp":1768402957469,"version":"3.49.0"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2019,2,23]],"date-time":"2019-02-23T00:00:00Z","timestamp":1550880000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,2,23]],"date-time":"2019-02-23T00:00:00Z","timestamp":1550880000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100009634","name":"Susan G. Komen","doi-asserted-by":"publisher","award":["SAC160073"],"award-info":[{"award-number":["SAC160073"]}],"id":[{"id":"10.13039\/100009634","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001006","name":"Breast Cancer Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001006","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["1F31CA203055-01"],"award-info":[{"award-number":["1F31CA203055-01"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["K99 CA193734"],"award-info":[{"award-number":["K99 CA193734"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["1F30CA203154-01"],"award-info":[{"award-number":["1F30CA203154-01"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA047904"],"award-info":[{"award-number":["P30CA047904"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P50CA090440"],"award-info":[{"award-number":["P50CA090440"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006751","name":"U.S. Army","doi-asserted-by":"publisher","award":["BC160764"],"award-info":[{"award-number":["BC160764"]}],"id":[{"id":"10.13039\/100006751","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006751","name":"U.S. Army","doi-asserted-by":"publisher","award":["BC110619"],"award-info":[{"award-number":["BC110619"]}],"id":[{"id":"10.13039\/100006751","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002590","name":"American Lung Association","doi-asserted-by":"publisher","award":["LCD 257864"],"award-info":[{"award-number":["LCD 257864"]}],"id":[{"id":"10.13039\/100002590","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001368","name":"V Foundation for Cancer Research","doi-asserted-by":"publisher","award":["Scholar Award"],"award-info":[{"award-number":["Scholar Award"]}],"id":[{"id":"10.13039\/100001368","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006156","name":"Sidney Kimmel Foundation for Cancer Research","doi-asserted-by":"publisher","award":["SKF-15-099"],"award-info":[{"award-number":["SKF-15-099"]}],"id":[{"id":"10.13039\/100006156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000862","name":"Doris Duke Charitable Foundation","doi-asserted-by":"publisher","award":["2015097"],"award-info":[{"award-number":["2015097"]}],"id":[{"id":"10.13039\/100000862","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000048","name":"American Cancer Society","doi-asserted-by":"publisher","award":["132939-RSG-18-185-01-TBG"],"award-info":[{"award-number":["132939-RSG-18-185-01-TBG"]}],"id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s10549-019-05161-8","type":"journal-article","created":{"date-parts":[[2019,2,23]],"date-time":"2019-02-23T07:39:18Z","timestamp":1550907558000},"page":"327-337","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["SNAIL is induced by tamoxifen and leads to growth inhibition in invasive lobular breast carcinoma"],"prefix":"10.1007","volume":"175","author":[{"given":"Emily A.","family":"Bossart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilgun","family":"Tasdemir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew J.","family":"Sikora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Bahreini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin M.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Basudan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Britta M.","family":"Jacobsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy F.","family":"Burns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8700-0251","authenticated-orcid":false,"given":"Steffi","family":"Oesterreich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,2,23]]},"reference":[{"key":"5161_CR1","unstructured":"Howlader N, Krapcho NA, Miller M, Bishop D, Kosary CL et al SEER Cancer Stat Rev. 1975\u20132014. 2017 April 2017; Based on November 2016 SEER data submission]"},{"key":"5161_CR2","unstructured":"Society AC (2017) Cancer Facts and Figures 2017"},{"issue":"4","key":"5161_CR3","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1177\/1758834016644156","volume":"8","author":"R Barroso-Sousa","year":"2016","unstructured":"Barroso-Sousa R, Metzger-Filho O (2016) Differences between invasive lobular and invasive ductal carcinoma of the breast: results and therapeutic implications. Ther Adv Med Oncol 8(4):261\u2013266","journal-title":"Ther Adv Med Oncol"},{"issue":"2","key":"5161_CR4","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1016\/j.cell.2015.09.033","volume":"163","author":"G Ciriello","year":"2015","unstructured":"Ciriello G et al (2015) Comprehensive molecular portraits of invasive lobular breast cancer. Cell 163(2):506\u2013519","journal-title":"Cell"},{"issue":"7","key":"5161_CR5","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.prp.2016.05.002","volume":"212","author":"M Christgen","year":"2016","unstructured":"Christgen M et al (2016) Lobular breast cancer: clinical, molecular and morphological characteristics. Pathol Res Pract 212(7):583\u2013597","journal-title":"Pathol Res Pract"},{"key":"5161_CR6","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.semcancer.2017.03.007","volume":"44","author":"C Desmedt","year":"2017","unstructured":"Desmedt C et al (2017) Transcriptomic and genomic features of invasive lobular breast cancer. Semin Cancer Biol 44:98\u2013105","journal-title":"Semin Cancer Biol"},{"issue":"10","key":"5161_CR7","doi-asserted-by":"publisher","first-page":"955","DOI":"10.4161\/cbt.10.10.13879","volume":"10","author":"GK Malhotra","year":"2010","unstructured":"Malhotra GK et al (2010) Histological, molecular and functional subtypes of breast cancers. Cancer Biol Ther 10(10):955\u2013960","journal-title":"Cancer Biol Ther"},{"issue":"3","key":"5161_CR8","doi-asserted-by":"publisher","first-page":"R149","DOI":"10.1186\/bcr767","volume":"6","author":"G Arpino","year":"2004","unstructured":"Arpino G et al (2004) Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome. Breast Cancer Res 6(3):R149\u2013R156","journal-title":"Breast Cancer Res"},{"issue":"12","key":"5161_CR9","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s13058-015-0519-x","volume":"17","author":"AE McCart Reed","year":"2015","unstructured":"McCart Reed AE et al (2015) Invasive lobular carcinoma of the breast: morphology, biomarkers and \u2018omics. Breast Cancer Res 17(12):12","journal-title":"Breast Cancer Res"},{"issue":"94","key":"5161_CR10","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1186\/s13058-015-0605-0","volume":"17","author":"K Johnson","year":"2015","unstructured":"Johnson K, Sarma D, Hwang ES (2015) Lobular breast cancer series: imaging. Breast Cancer Res 17(94):94","journal-title":"Breast Cancer Res"},{"key":"5161_CR11","first-page":"986517","volume":"2013","author":"JD Sobinsky","year":"2013","unstructured":"Sobinsky JD et al. (2013) Unusual metastatic patterns of invasive lobular carcinoma of the breast. Case Rep Oncol Med 2013:986517","journal-title":"Case Rep Oncol Med"},{"issue":"4","key":"5161_CR12","doi-asserted-by":"crossref","first-page":"287","DOI":"10.59566\/IJBS.2014.10287","volume":"10","author":"MT Shakoor","year":"2014","unstructured":"Shakoor MT et al (2014) Unique presentations of invasive lobular breast cancer: a case series. Int J Biomed Sci 10(4):287\u2013293","journal-title":"Int J Biomed Sci"},{"issue":"6","key":"5161_CR13","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1055\/s-0043-109374","volume":"77","author":"A Mathew","year":"2017","unstructured":"Mathew A et al (2017) Distinct pattern of metastases in patients with invasive lobular carcinoma of the breast. Geburtshilfe Frauenheilkd 77(6):660\u2013666","journal-title":"Geburtshilfe Frauenheilkd"},{"issue":"4","key":"5161_CR14","doi-asserted-by":"publisher","first-page":"513","DOI":"10.2174\/092986711794480177","volume":"18","author":"F Lumachi","year":"2011","unstructured":"Lumachi F et al (2011) Endocrine therapy of breast cancer. Curr Med Chem 18(4):513\u2013522","journal-title":"Curr Med Chem"},{"issue":"9","key":"5161_CR15","doi-asserted-by":"publisher","first-page":"e0182397","DOI":"10.1371\/journal.pone.0182397","volume":"12","author":"Z Chen","year":"2017","unstructured":"Chen Z et al (2017) Invasive lobular carcinoma of the breast: a special histological type compared with invasive ductal carcinoma. PLoS One 12(9):e0182397","journal-title":"PLoS One"},{"issue":"3","key":"5161_CR16","doi-asserted-by":"publisher","first-page":"R235","DOI":"10.1530\/ERC-14-0092","volume":"21","author":"VC Jordan","year":"2014","unstructured":"Jordan VC (2014) Tamoxifen as the first targeted long-term adjuvant therapy for breast cancer. Endocr Relat Cancer 21(3):R235\u2013R246","journal-title":"Endocr Relat Cancer"},{"issue":"5","key":"5161_CR17","doi-asserted-by":"publisher","first-page":"990","DOI":"10.5306\/wjco.v5.i5.990","volume":"5","author":"A Milani","year":"2014","unstructured":"Milani A et al (2014) Overcoming endocrine resistance in metastatic breast cancer: current evidence and future directions. World J Clin Oncol 5(5):990\u20131001","journal-title":"World J Clin Oncol"},{"issue":"2","key":"5161_CR18","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3390\/jcm5020017","volume":"5","author":"BN Smith","year":"2016","unstructured":"Smith BN, Bhowmick NA (2016) Role of EMT in metastasis and therapy resistance. J Clin Med. 5(2):17","journal-title":"J Clin Med"},{"issue":"18","key":"5161_CR19","doi-asserted-by":"publisher","first-page":"3006","DOI":"10.1200\/JCO.2007.14.9336","volume":"26","author":"BC Pestalozzi","year":"2008","unstructured":"Pestalozzi BC et al (2008) Distinct clinical and prognostic features of infiltrating lobular carcinoma of the breast: combined results of 15 International Breast Cancer Study Group clinical trials. J Clin Oncol 26(18):3006\u20133014","journal-title":"J Clin Oncol"},{"key":"5161_CR20","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/2193-1801-3-70","volume":"3","author":"U Narbe","year":"2014","unstructured":"Narbe U et al (2014) Invasive lobular carcinoma of the breast: long-term prognostic value of Ki67 and histological grade, alone and in combination with estrogen receptor. Springerplus 3:70","journal-title":"Springerplus"},{"key":"5161_CR21","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1111\/his.12572","volume":"66","author":"MJ Engstr\u00f8m","year":"2015","unstructured":"Engstr\u00f8m MJ et al (2015) Invasive lobular breast cancer: the prognostic impact of histopathological grade, E-cadherin and molecular subtypes. Histopathology 66:409\u2013419","journal-title":"Histopathology"},{"key":"5161_CR22","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1186\/s12885-016-2275-4","volume":"16","author":"Y Adachi","year":"2016","unstructured":"Adachi Y et al (2016) Comparison of clinical outcomes between luminal invasive ductal carcinoma and luminal invasive lobular carcinoma. BMC Cancer 16:248","journal-title":"BMC Cancer"},{"key":"5161_CR23","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1007\/s12282-017-0812-x","volume":"25","author":"K Araki","year":"2017","unstructured":"Araki K, Miyoshi Y (2017) Mechanism of resistance to endocrine therapy in breast cancer: the important role of PI3K\/Akt\/mTOR in estrogen receptor-positive, HER2-negative breast cancer. Breast Cancer (Tokyo Japan) 25:392\u2013401","journal-title":"Breast Cancer (Tokyo Japan)"},{"issue":"3","key":"5161_CR24","doi-asserted-by":"publisher","first-page":"256","DOI":"10.4062\/biomolther.2012.20.3.256","volume":"20","author":"M Chang","year":"2012","unstructured":"Chang M (2012) Tamoxifen resistance in breast cancer. Biomol Ther (Seoul) 20(3):256\u2013267","journal-title":"Biomol Ther (Seoul)"},{"issue":"3","key":"5161_CR25","doi-asserted-by":"publisher","first-page":"135","DOI":"10.6026\/97320630012135","volume":"12","author":"S Ali","year":"2016","unstructured":"Ali S et al (2016) Molecular mechanisms and mode of tamoxifen resistance in breast cancer. Bioinformation 12(3):135\u2013139","journal-title":"Bioinformation"},{"issue":"5","key":"5161_CR26","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1158\/0008-5472.CAN-13-2779","volume":"74","author":"MJ Sikora","year":"2014","unstructured":"Sikora MJ et al (2014) Invasive lobular carcinoma cell lines are characterized by unique estrogen-mediated gene expression patterns and altered tamoxifen response. Cancer Res 74(5):1463\u20131474","journal-title":"Cancer Res"},{"issue":"2","key":"5161_CR27","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s10911-010-9179-8","volume":"15","author":"AG de Herreros","year":"2010","unstructured":"de Herreros AG et al (2010) Snail family regulation and epithelial mesenchymal transitions in breast cancer progression. J Mammary Gland Biol Neoplasia 15(2):135\u2013147","journal-title":"J Mammary Gland Biol Neoplasia"},{"issue":"6","key":"5161_CR28","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1245\/ASO.2005.04.010","volume":"12","author":"TA Martin","year":"2005","unstructured":"Martin TA et al (2005) Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer. Ann Surg Oncol 12(6):488\u2013496","journal-title":"Ann Surg Oncol"},{"issue":"6","key":"5161_CR29","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1038\/nrc2131","volume":"7","author":"H Peinado","year":"2007","unstructured":"Peinado H, Olmeda D, Cano A (2007) Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7(6):415\u2013428","journal-title":"Nat Rev Cancer"},{"issue":"3","key":"5161_CR30","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.ccr.2005.07.009","volume":"8","author":"SE Moody","year":"2005","unstructured":"Moody SE et al (2005) The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell 8(3):197\u2013209","journal-title":"Cancer Cell"},{"issue":"8","key":"5161_CR31","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1002\/cncr.20946","volume":"103","author":"S Elloul","year":"2005","unstructured":"Elloul S et al (2005) Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer 103(8):1631\u20131643","journal-title":"Cancer"},{"issue":"8","key":"5161_CR32","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1007\/s10585-011-9412-x","volume":"28","author":"S Dubois-Marshall","year":"2011","unstructured":"Dubois-Marshall S et al (2011) Two possible mechanisms of epithelial to mesenchymal transition in invasive ductal breast cancer. Clin Exp Metastasis 28(8):811\u2013818","journal-title":"Clin Exp Metastasis"},{"issue":"2","key":"5161_CR33","doi-asserted-by":"publisher","first-page":"151","DOI":"10.5732\/cjc.009.10447","volume":"29","author":"WJ Chen","year":"2010","unstructured":"Chen WJ et al (2010) Multidrug resistance in breast cancer cells during epithelial-mesenchymal transition is modulated by breast cancer resistant protein. Chin J Cancer 29(2):151\u2013157","journal-title":"Chin J Cancer"},{"issue":"17","key":"5161_CR34","doi-asserted-by":"publisher","first-page":"7559","DOI":"10.1128\/MCB.24.17.7559-7566.2004","volume":"24","author":"M Kajita","year":"2004","unstructured":"Kajita M, McClinic KN, Wade PA (2004) Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress. Mol Cell Biol 24(17):7559\u20137566","journal-title":"Mol Cell Biol"},{"issue":"2","key":"5161_CR35","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.stem.2010.12.007","volume":"8","author":"TA Proia","year":"2011","unstructured":"Proia TA et al (2011) Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. Cell Stem Cell 8(2):149\u2013163","journal-title":"Cell Stem Cell"},{"issue":"4","key":"5161_CR36","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1002\/path.4668","volume":"238","author":"AE McCart Reed","year":"2016","unstructured":"McCart Reed AE et al (2016) An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas. J Pathol 238(4):489\u2013494","journal-title":"J Pathol"},{"issue":"2","key":"5161_CR37","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1007\/s10549-011-1860-0","volume":"132","author":"M Morrogh","year":"2012","unstructured":"Morrogh M et al (2012) Cadherin-catenin complex dissociation in lobular neoplasia of the breast. Breast Cancer Res Treat 132(2):641\u2013652","journal-title":"Breast Cancer Res Treat"},{"issue":"2","key":"5161_CR38","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1007\/s10549-012-2377-x","volume":"137","author":"P Jambal","year":"2013","unstructured":"Jambal P et al (2013) Estrogen switches pure mucinous breast cancer to invasive lobular carcinoma with mucinous features. Breast Cancer Res Treat 137(2):431\u2013448","journal-title":"Breast Cancer Res Treat"},{"issue":"21","key":"5161_CR39","doi-asserted-by":"publisher","first-page":"6209","DOI":"10.1158\/0008-5472.CAN-18-1416","volume":"78","author":"N Tasdemir","year":"2018","unstructured":"Tasdemir N et al (2018) Comprehensive phenotypic characterization of human invasive lobular carcinoma cell lines in 2D and 3D cultures. Cancer Res 78(21):6209\u20136222","journal-title":"Cancer Res"},{"issue":"9","key":"5161_CR40","doi-asserted-by":"publisher","first-page":"3665","DOI":"10.1073\/pnas.1019736108","volume":"108","author":"KL Meerbrey","year":"2011","unstructured":"Meerbrey KL et al (2011) The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc Natl Acad Sci USA 108(9):3665\u20133670","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"5161_CR41","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/s13058-016-0748-7","volume":"18","author":"MJ Sikora","year":"2016","unstructured":"Sikora MJ et al (2016) WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines. Breast Cancer Res 18(1):92","journal-title":"Breast Cancer Res"},{"issue":"2","key":"5161_CR42","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/s10911-012-9255-3","volume":"17","author":"FL Shaw","year":"2012","unstructured":"Shaw FL et al (2012) A detailed mammosphere assay protocol for the quantification of breast stem cell activity. J Mammary Gland Biol Neoplasia 17(2):111\u2013117","journal-title":"J Mammary Gland Biol Neoplasia"},{"issue":"11","key":"5161_CR43","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1038\/s41389-017-0002-x","volume":"6","author":"JC Harrell","year":"2017","unstructured":"Harrell JC, Shroka TM, Jacobsen BM (2017) Estrogen induces c-Kit and an aggressive phenotype in a model of invasive lobular breast cancer. Oncogenesis 6(11):396","journal-title":"Oncogenesis"},{"issue":"6","key":"5161_CR44","doi-asserted-by":"publisher","first-page":"2147","DOI":"10.1002\/jcb.24087","volume":"113","author":"AM Scherbakov","year":"2012","unstructured":"Scherbakov AM et al (2012) The relationships between snail1 and estrogen receptor signaling in breast cancer cells. J Cell Biochem 113(6):2147\u20132155","journal-title":"J Cell Biochem"},{"issue":"6","key":"5161_CR45","doi-asserted-by":"publisher","first-page":"e65556","DOI":"10.1371\/journal.pone.0065556","volume":"8","author":"M Wang","year":"2013","unstructured":"Wang M et al (2013) AIB1 cooperates with ERalpha to promote epithelial mesenchymal transition in breast cancer through SNAI1 activation. PLoS ONE 8(6):e65556","journal-title":"PLoS ONE"},{"issue":"7381","key":"5161_CR46","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1038\/nature10730","volume":"481","author":"CS Ross-Innes","year":"2012","unstructured":"Ross-Innes CS et al (2012) Differential oestrogen receptor binding is associated with clinical outcome in breast cancer. Nature 481(7381):389\u2013393","journal-title":"Nature"},{"key":"5161_CR47","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s13058-015-0517-z","volume":"17","author":"M Christgen","year":"2015","unstructured":"Christgen M, Derksen P (2015) Lobular breast cancer: molecular basis, mouse and cellular models. Breast Cancer Res 17:16","journal-title":"Breast Cancer Res"},{"issue":"10","key":"5161_CR48","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1038\/ncb1173","volume":"6","author":"BP Zhou","year":"2004","unstructured":"Zhou BP et al (2004) Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol 6(10):931\u2013940","journal-title":"Nat Cell Biol"},{"issue":"10","key":"5161_CR49","doi-asserted-by":"publisher","first-page":"1769","DOI":"10.1038\/sj.bjc.6605369","volume":"101","author":"K Lundgren","year":"2009","unstructured":"Lundgren K, Nordenskjold B, Landberg G, Hypoxia (2009) Snail and incomplete epithelial-mesenchymal transition in breast cancer. Br J Cancer 101(10):1769\u20131781","journal-title":"Br J Cancer"},{"issue":"10","key":"5161_CR50","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1101\/gad.294104","volume":"18","author":"S Vega","year":"2004","unstructured":"Vega S et al (2004) Snail blocks the cell cycle and confers resistance to cell death. Genes Dev 18(10):1131\u20131143","journal-title":"Genes Dev"},{"issue":"4","key":"5161_CR51","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/j.cell.2008.03.027","volume":"133","author":"SA Mani","year":"2008","unstructured":"Mani SA et al (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133(4):704\u2013715","journal-title":"Cell"},{"issue":"25","key":"5161_CR52","doi-asserted-by":"publisher","first-page":"2772","DOI":"10.1200\/JCO.2015.60.8133","volume":"33","author":"O Metzger Filho","year":"2015","unstructured":"Metzger Filho O et al (2015) Relative effectiveness of letrozole compared with tamoxifen for patients with lobular carcinoma in the BIG 1\u201398 trial. J Clin Oncol 33(25):2772\u20132779","journal-title":"J Clin Oncol"},{"issue":"21","key":"5161_CR53","doi-asserted-by":"publisher","first-page":"8908","DOI":"10.1158\/0008-5472.CAN-08-2669","volume":"68","author":"RB Riggins","year":"2008","unstructured":"Riggins RB et al (2008) ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer. Cancer Res 68(21):8908\u20138917","journal-title":"Cancer Res"},{"key":"5161_CR54","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.mce.2017.09.024","volume":"471","author":"H Stires","year":"2018","unstructured":"Stires H et al (2018) Integrated molecular analysis of Tamoxifen-resistant invasive lobular breast cancer cells identifies MAPK and GRM\/mGluR signaling as therapeutic vulnerabilities. Mol Cell Endocrinol 471:105\u2013117","journal-title":"Mol Cell Endocrinol"},{"issue":"8","key":"5161_CR55","doi-asserted-by":"publisher","first-page":"e0136845","DOI":"10.1371\/journal.pone.0136845","volume":"10","author":"T van Agthoven","year":"2015","unstructured":"van Agthoven T et al (2015) Breast cancer anti-estrogen resistance 4 (BCAR4) drives proliferation of IPH-926 lobular carcinoma cells. PLoS ONE 10(8):e0136845","journal-title":"PLoS ONE"},{"issue":"9","key":"5161_CR56","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1038\/nrc3793","volume":"14","author":"MS Sosa","year":"2014","unstructured":"Sosa MS, Bragado P, Aguirre-Ghiso JA (2014) Mechanisms of disseminated cancer cell dormancy: an awakening field. Nat Rev Cancer 14(9):611\u2013622","journal-title":"Nat Rev Cancer"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10549-019-05161-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-019-05161-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-019-05161-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T22:14:40Z","timestamp":1694643280000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10549-019-05161-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,23]]},"references-count":56,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["5161"],"URL":"https:\/\/doi.org\/10.1007\/s10549-019-05161-8","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,23]]},"assertion":[{"value":"21 December 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 February 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 February 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Dr. Timothy F. Burns serves on an Advisory Board for AbbVie, Inc., and Dr. Oesterreich is a member of the External Scientific Advisory Board Panel of NSABP. The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Research involving human and animal rights"}}]}}