{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T17:33:45Z","timestamp":1778693625136,"version":"3.51.4"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,5,12]],"date-time":"2020-05-12T00:00:00Z","timestamp":1589241600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,5,12]],"date-time":"2020-05-12T00:00:00Z","timestamp":1589241600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"None"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1007\/s10549-020-05666-7","type":"journal-article","created":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T10:33:43Z","timestamp":1589884423000},"page":"79-83","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The natural history of untreated estrogen receptor-positive, Her2-negative invasive breast cancer"],"prefix":"10.1007","volume":"182","author":[{"given":"Kristin E.","family":"Rojas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna-Marie","family":"Manasseh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Rojas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Mattocks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leah","family":"Portnow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Kantharia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Zelenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Giuliano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick I.","family":"Borgen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,5,12]]},"reference":[{"key":"5666_CR1","doi-asserted-by":"publisher","first-page":"20140379","DOI":"10.1098\/rstb.2014.0379","volume":"370","author":"T Kirkwood","year":"2015","unstructured":"Kirkwood T (2015) Deciphering death: a commentary on Gompertz (1825) \u2018On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies\u2019. Phil Trans R Soc B 370:20140379","journal-title":"Phil Trans R Soc B"},{"key":"5666_CR2","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1002\/jso.2930600216","volume":"60","author":"JS Spratt","year":"1995","unstructured":"Spratt JS, Meyer JS, Spratt JA (1995) Rates of growth of human solid neoplasms: part I. J Surg Oncol 60:137\u2013146. https:\/\/doi.org\/10.1002\/jso.2930600216","journal-title":"J Surg Oncol"},{"key":"5666_CR3","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1002\/1096-9098(199601)61:1<68::AID-JSO2930610102>3.0.CO;2-E","volume":"61","author":"JS Spratt","year":"1996","unstructured":"Spratt JS, Meyer JS, Spratt JA (1996) Rates of growth of human neoplasms: part II. J Surg Oncol 61:68\u201383","journal-title":"J Surg Oncol"},{"issue":"9","key":"5666_CR4","doi-asserted-by":"publisher","first-page":"2227","DOI":"10.1007\/s00330-014-3256-0","volume":"24","author":"E Ryu","year":"2014","unstructured":"Ryu E, Change J, Seo M et al (2014) Tumour volume doubling time of molecular breast cancer subtypes assessed by serial breast ultrasound. Eur Radiol 24(9):2227\u20132235","journal-title":"Eur Radiol"},{"key":"5666_CR5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0143811.g004","author":"HG Moon","year":"2015","unstructured":"Moon HG, Kim N, Jeong S, Lee M, Moon H et al (2015) The clinical significance and molecular features of the spatial tumor shapes in breast cancers. PLoS ONE. https:\/\/doi.org\/10.1371\/journal.pone.0143811.g004","journal-title":"PLoS ONE"},{"issue":"5","key":"5666_CR6","doi-asserted-by":"publisher","first-page":"1888","DOI":"10.1002\/1097-0142(197905)43:5<1888::AID-CNCR2820430545>3.0.CO;2-M","volume":"43","author":"L Heuser","year":"1979","unstructured":"Heuser L, Spratt JS, Polk HC (1979) Growth rates of primary breast cancers. Cancer 43(5):1888\u20131894","journal-title":"Cancer"},{"issue":"8","key":"5666_CR7","doi-asserted-by":"publisher","first-page":"2198","DOI":"10.1002\/1097-0142(19800415)45:8<2198::AID-CNCR2820450832>3.0.CO;2-7","volume":"45","author":"D von Fournier","year":"1980","unstructured":"von Fournier D, Weber E, Hoeffken W et al (1980) Growth rate of 147 mammary carcinomas. Cancer 45(8):2198\u20132207","journal-title":"Cancer"},{"issue":"2","key":"5666_CR8","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1007\/s12282-018-0914-0","volume":"26","author":"K Nakashima","year":"2019","unstructured":"Nakashima K, Uematsu T, Takahashi K et al (2019) Does breast cancer growth rate really depend on tumor subtype? Measurement of tumor doubling time using serial ultrasonography between diagnosis and surgery. Breast Cancer 26(2):206\u2013214","journal-title":"Breast Cancer"},{"key":"5666_CR9","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3233\/BD-2001-12115","volume":"12","author":"K Kern","year":"2001","unstructured":"Kern K (2001) The delayed diagnosis of breast cancer: medicolegal implications and risk prevention for surgeons. Breast Dis 12:145\u2013158","journal-title":"Breast Dis"},{"key":"5666_CR10","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1001\/archsurg.1994.01420280073009","volume":"129","author":"K Kern","year":"1994","unstructured":"Kern K (1994) Medicolegal analysis of the delayed diagnosis of cancer in 338 cases in the United States. Arch Surg 129:397\u2013404","journal-title":"Arch Surg"},{"issue":"4","key":"5666_CR11","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1097\/SLA.0000000000000924","volume":"260","author":"JC Boughey","year":"2014","unstructured":"Boughey JC, McCall LM, Ballman KV et al (2014) Tumor biology correlates with rates of breasy conserving surgery and pathologic complete response after neoadjuvant chemotherapy for breast cancer findings from the ACOSOG Z1071 (Alliance) prospective multicenter clinical trial. Ann Surg 260(4):608\u2013616","journal-title":"Ann Surg"},{"issue":"11","key":"5666_CR12","doi-asserted-by":"publisher","first-page":"3467","DOI":"10.1245\/s10434-016-5246-8","volume":"23","author":"A Mamtani","year":"2016","unstructured":"Mamtani A, Barrio A, King T et al (2016) How often does neoadjuvant chemotherapy avoid axillary dissection in patients with histologically confirmed nodal metastases: results of a prospective study. Ann Surg Oncol 23(11):3467\u20133474","journal-title":"Ann Surg Oncol"},{"key":"5666_CR13","doi-asserted-by":"publisher","first-page":"2817","DOI":"10.1056\/NEJMoa041588","volume":"351","author":"S Paik","year":"2004","unstructured":"Paik S, Shak S, Tang G et al (2004) A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. New Engl J Med 351:2817\u20132826","journal-title":"New Engl J Med"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-020-05666-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10549-020-05666-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-020-05666-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T00:46:21Z","timestamp":1620780381000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10549-020-05666-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,12]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["5666"],"URL":"https:\/\/doi.org\/10.1007\/s10549-020-05666-7","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,12]]},"assertion":[{"value":"15 November 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors report no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}