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Besic and B. Strazisar have received a research Grant Trial KCT 04\/2015-DORETAonko\/si from the pharmaceutical company Krka d.d. Novo mesto. J. Smrekar has received a honorarium for the statistical analysis of our study from the pharmaceutical company Krka d.d. Novo mesto.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study Trial KCT 04\/2015-DORETAonko\/si, EudraCT Number: 2015-000992-28 met the guidelines of their responsible governmental agency and was reviewed and approved by The National Medical Ethics Committee of the Republic of Slovenia (Approval number 32\/03\/15). Our study was approved by the Institutional Review Board of the Institute of Oncology Ljubljana.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}