{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T12:08:38Z","timestamp":1782389318485,"version":"3.54.5"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T00:00:00Z","timestamp":1651536000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30CA15083-45"],"award-info":[{"award-number":["P30CA15083-45"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1007\/s10549-022-06600-9","type":"journal-article","created":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T05:02:40Z","timestamp":1651554160000},"page":"149-158","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Serum hormone levels and normal breast histology among premenopausal women"],"prefix":"10.1007","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9222-8808","authenticated-orcid":false,"given":"Mark E.","family":"Sherman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"de Bel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Heckman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Launia J.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Ogony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melody","family":"Stallings-Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"Hilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy C.","family":"Degnim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Vierkant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"Hoskin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Pacheco-Spann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill E.","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Maria","family":"Storniolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodi M.","family":"Carter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey J.","family":"Winham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek C.","family":"Radisky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"van der Laak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,3]]},"reference":[{"issue":"2","key":"6600_CR1","first-page":"231","volume":"55","author":"SR Wellings","year":"1975","unstructured":"Wellings SR, Jensen HM, Marcum RG (1975) An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst 55(2):231\u2013273","journal-title":"J Natl Cancer Inst"},{"key":"6600_CR2","doi-asserted-by":"publisher","DOI":"10.20517\/2394-4722.2019.01","author":"TR Wallace","year":"2019","unstructured":"Wallace TR, Tarullo SE, Crump LS et al (2019) Studies of postpartum mammary gland involution reveal novel pro-metastatic mechanisms. J Cancer Metastasis Treat. https:\/\/doi.org\/10.20517\/2394-4722.2019.01","journal-title":"J Cancer Metastasis Treat"},{"issue":"2","key":"6600_CR3","doi-asserted-by":"publisher","first-page":"R31","DOI":"10.1186\/bcr3633","volume":"16","author":"S Jindal","year":"2014","unstructured":"Jindal S, Gao D, Bell P et al (2014) Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling. Breast Cancer Res 16(2):R31. https:\/\/doi.org\/10.1186\/bcr3633","journal-title":"Breast Cancer Res"},{"issue":"8","key":"6600_CR4","doi-asserted-by":"publisher","first-page":"1803","DOI":"10.1002\/ijc.29181","volume":"136","author":"HA Martinson","year":"2015","unstructured":"Martinson HA, Jindal S, Durand-Rougely C et al (2015) Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progression. Int J Cancer 136(8):1803\u20131813. https:\/\/doi.org\/10.1002\/ijc.29181","journal-title":"Int J Cancer"},{"issue":"1","key":"6600_CR5","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s10911-007-9039-3","volume":"12","author":"P Schedin","year":"2007","unstructured":"Schedin P, O\u2019Brien J, Rudolph M et al (2007) Microenvironment of the involuting mammary gland mediates mammary cancer progression. J Mammary Gland Biol Neoplasia 12(1):71\u201382. https:\/\/doi.org\/10.1007\/s10911-007-9039-3","journal-title":"J Mammary Gland Biol Neoplasia"},{"issue":"9","key":"6600_CR6","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1038\/nm.2416","volume":"17","author":"TR Lyons","year":"2011","unstructured":"Lyons TR, O\u2019Brien J, Borges VF et al (2011) Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. Nat Med 17(9):1109\u20131115. https:\/\/doi.org\/10.1038\/nm.2416","journal-title":"Nat Med"},{"issue":"3","key":"6600_CR7","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1093\/jnci\/djs505","volume":"105","author":"JM Faupel-Badger","year":"2013","unstructured":"Faupel-Badger JM, Arcaro KF, Balkam JJ et al (2013) Postpartum remodeling, lactation, and breast cancer risk: summary of a National Cancer Institute-sponsored workshop. J Natl Cancer Inst 105(3):166\u2013174. https:\/\/doi.org\/10.1093\/jnci\/djs505","journal-title":"J Natl Cancer Inst"},{"issue":"22","key":"6600_CR8","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1093\/jnci\/djj439","volume":"98","author":"TR Milanese","year":"2006","unstructured":"Milanese TR, Hartmann LC, Sellers TA et al (2006) Age-related lobular involution and risk of breast cancer. J Natl Cancer Inst 98(22):1600\u20131607. https:\/\/doi.org\/10.1093\/jnci\/djj439","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"6600_CR9","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/s10549-016-3908-7","volume":"159","author":"JD Figueroa","year":"2016","unstructured":"Figueroa JD, Pfeiffer RM, Brinton LA et al (2016) Standardized measures of lobular involution and subsequent breast cancer risk among women with benign breast disease: a nested case-control study. Breast Cancer Res Treat 159(1):163\u2013172. https:\/\/doi.org\/10.1007\/s10549-016-3908-7","journal-title":"Breast Cancer Res Treat"},{"key":"6600_CR10","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dju286","author":"JD Figueroa","year":"2014","unstructured":"Figueroa JD, Pfeiffer RM, Patel DA et al (2014) Terminal duct lobular unit involution of the normal breast: implications for breast cancer etiology. J Natl Cancer Inst. https:\/\/doi.org\/10.1093\/jnci\/dju286","journal-title":"J Natl Cancer Inst"},{"issue":"11","key":"6600_CR11","doi-asserted-by":"publisher","first-page":"2358","DOI":"10.1158\/1055-9965.EPI-20-0723","volume":"29","author":"KH Kensler","year":"2020","unstructured":"Kensler KH, Liu EZF, Wetstein SC et al (2020) Automated quantitative measures of terminal duct lobular unit involution and breast cancer risk. Cancer Epidemiol Biomarkers Prev 29(11):2358\u20132368. https:\/\/doi.org\/10.1158\/1055-9965.EPI-20-0723","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"7","key":"6600_CR12","doi-asserted-by":"publisher","first-page":"1404","DOI":"10.1002\/cncr.24167","volume":"115","author":"HJ Baer","year":"2009","unstructured":"Baer HJ, Collins LC, Connolly JL et al (2009) Lobule type and subsequent breast cancer risk: results from the Nurses\u2019 Health Studies. Cancer 115(7):1404\u20131411. https:\/\/doi.org\/10.1002\/cncr.24167","journal-title":"Cancer"},{"issue":"1","key":"6600_CR13","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s13058-019-1128-x","volume":"21","author":"J Santucci-Pereira","year":"2019","unstructured":"Santucci-Pereira J, Zeleniuch-Jacquotte A, Afanasyeva Y et al (2019) Genomic signature of parity in the breast of premenopausal women. Breast Cancer Res 21(1):46. https:\/\/doi.org\/10.1186\/s13058-019-1128-x","journal-title":"Breast Cancer Res"},{"issue":"1","key":"6600_CR14","doi-asserted-by":"publisher","first-page":"22","DOI":"10.7326\/M18-1323","volume":"170","author":"HB Nichols","year":"2019","unstructured":"Nichols HB, Schoemaker MJ, Cai J et al (2019) Breast cancer risk after recent childbirth: a pooled analysis of 15 prospective studies. Ann Intern Med 170(1):22\u201330. https:\/\/doi.org\/10.7326\/M18-1323","journal-title":"Ann Intern Med"},{"key":"6600_CR15","doi-asserted-by":"publisher","unstructured":"Endogenous H, Breast Cancer Collaborative G, Key TJ et al (2013) Sex hormones and risk of breast cancer in premenopausal women: a collaborative reanalysis of individual participant data from seven prospective studies. Lancet Oncol 14(10):1009\u20131019. https:\/\/doi.org\/10.1016\/S1470-2045(13)70301-2","DOI":"10.1016\/S1470-2045(13)70301-2"},{"issue":"1","key":"6600_CR16","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1038\/s41416-021-01392-z","volume":"125","author":"S Tin Tin","year":"2021","unstructured":"Tin Tin S, Reeves GK, Key TJ (2021) Endogenous hormones and risk of invasive breast cancer in pre- and post-menopausal women: findings from the UK Biobank. Br J Cancer 125(1):126\u2013134. https:\/\/doi.org\/10.1038\/s41416-021-01392-z","journal-title":"Br J Cancer"},{"issue":"8","key":"6600_CR17","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1093\/jnci\/94.8.606","volume":"94","author":"T Key","year":"2002","unstructured":"Key T, Appleby P, Barnes I et al (2002) Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies. J Natl Cancer Inst 94(8):606\u2013616. https:\/\/doi.org\/10.1093\/jnci\/94.8.606","journal-title":"J Natl Cancer Inst"},{"key":"6600_CR18","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.canlet.2021.01.012","volume":"503","author":"KA O'Leary","year":"2021","unstructured":"O\u2019Leary KA, Rugowski DE, Shea MP et al (2021) Prolactin synergizes with canonical Wnt signals to drive development of ER+ mammary tumors via activation of the Notch pathway. Cancer Lett 503:231\u2013239. https:\/\/doi.org\/10.1016\/j.canlet.2021.01.012","journal-title":"Cancer Lett"},{"issue":"12","key":"6600_CR19","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1200\/JCO.2006.07.6356","volume":"25","author":"SS Tworoger","year":"2007","unstructured":"Tworoger SS, Eliassen AH, Sluss P et al (2007) A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer. J Clin Oncol 25(12):1482\u20131488. https:\/\/doi.org\/10.1200\/JCO.2006.07.6356","journal-title":"J Clin Oncol"},{"issue":"4","key":"6600_CR20","doi-asserted-by":"publisher","first-page":"pky055","DOI":"10.1093\/jncics\/pky055","volume":"2","author":"M Gabrielson","year":"2018","unstructured":"Gabrielson M, Ubhayasekera K, Ek B et al (2018) Inclusion of Plasma prolactin levels in current risk prediction models of premenopausal and postmenopausal breast cancer. JNCI Cancer Spectr 2(4):pky055. https:\/\/doi.org\/10.1093\/jncics\/pky055","journal-title":"JNCI Cancer Spectr"},{"issue":"15","key":"6600_CR21","doi-asserted-by":"publisher","first-page":"4810","DOI":"10.1158\/0008-5472.CAN-13-0665","volume":"73","author":"SS Tworoger","year":"2013","unstructured":"Tworoger SS, Eliassen AH, Zhang X et al (2013) A 20-year prospective study of plasma prolactin as a risk marker of breast cancer development. Cancer Res 73(15):4810\u20134819. https:\/\/doi.org\/10.1158\/0008-5472.CAN-13-0665","journal-title":"Cancer Res"},{"key":"6600_CR22","doi-asserted-by":"publisher","unstructured":"Endogenous H, Breast Cancer Collaborative G, Key TJ et al (2010) Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies. Lancet Oncol 11(6):530\u2013542. https:\/\/doi.org\/10.1016\/S1470-2045(10)70095-4","DOI":"10.1016\/S1470-2045(10)70095-4"},{"issue":"12","key":"6600_CR23","doi-asserted-by":"publisher","first-page":"2765","DOI":"10.1158\/1055-9965.EPI-14-0667","volume":"23","author":"ZG Khodr","year":"2014","unstructured":"Khodr ZG, Sherman ME, Pfeiffer RM et al (2014) Circulating sex hormones and terminal duct lobular unit involution of the normal breast. Cancer Epidemiol Biomarkers Prev 23(12):2765\u20132773. https:\/\/doi.org\/10.1158\/1055-9965.EPI-14-0667","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"3","key":"6600_CR24","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1002\/ijc.31333","volume":"143","author":"H Oh","year":"2018","unstructured":"Oh H, Pfeiffer RM, Falk RT et al (2018) Serum insulin-like growth factor (IGF)-I and IGF binding protein-3 in relation to terminal duct lobular unit involution of the normal breast in Caucasian and African American women: the Susan G. Komen. Tissue Bank Int J Cancer 143(3):496\u2013507. https:\/\/doi.org\/10.1002\/ijc.31333","journal-title":"Tissue Bank Int J Cancer"},{"issue":"7","key":"6600_CR25","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1002\/ijc.22482","volume":"120","author":"AH Eliassen","year":"2007","unstructured":"Eliassen AH, Tworoger SS, Hankinson SE (2007) Reproductive factors and family history of breast cancer in relation to plasma prolactin levels in premenopausal and postmenopausal women. Int J Cancer 120(7):1536\u20131541. https:\/\/doi.org\/10.1002\/ijc.22482","journal-title":"Int J Cancer"},{"issue":"1","key":"6600_CR26","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s12672-009-0003-0","volume":"1","author":"SE Hankinson","year":"2010","unstructured":"Hankinson SE, Eliassen AH (2010) Circulating sex steroids and breast cancer risk in premenopausal women. Horm Cancer 1(1):2\u201310. https:\/\/doi.org\/10.1007\/s12672-009-0003-0","journal-title":"Horm Cancer"},{"key":"6600_CR27","doi-asserted-by":"publisher","DOI":"10.1210\/endrev\/bnz001","author":"B Trabert","year":"2020","unstructured":"Trabert B, Sherman ME, Kannan N et al (2020) Progesterone and Breast Cancer. Endocr Rev. https:\/\/doi.org\/10.1210\/endrev\/bnz001","journal-title":"Endocr Rev"},{"issue":"Pt A","key":"6600_CR28","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.steroids.2014.12.011","volume":"99","author":"FZ Stanczyk","year":"2015","unstructured":"Stanczyk FZ, Mathews BW, Sherman ME (2015) Relationships of sex steroid hormone levels in benign and cancerous breast tissue and blood: a critical appraisal of current science. Steroids 99(Pt A):91\u2013102. https:\/\/doi.org\/10.1016\/j.steroids.2014.12.011","journal-title":"Steroids"},{"key":"6600_CR29","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1038\/s41523-021-00378-7","volume":"8","author":"TLG de Bel","year":"2022","unstructured":"de Bel TLG, Ogony J, Stallings-Mann M, Carter JM, Hilton T, Radisky DC, Vierkant RA, Broderick B, Hoskin TL, Winham SJ, Frost MH, Visscher DW, Allers T, Degnim AC, Sherman ME, van der Lakk JAWM (2022) Automated quantification of levels of breast terminal duct lobular (TDLU) involution using deep learning. NPJ Breast Cancer 8:13","journal-title":"NPJ Breast Cancer"},{"key":"6600_CR30","doi-asserted-by":"publisher","unstructured":"Sherman ME, Figueroa JD, Henry JE et al (2012) The Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center: a unique resource for defining the \u201cmolecular histology\u201d of the breast. Cancer Prev Res (Phila) 5(4):528\u2013535. https:\/\/doi.org\/10.1158\/1940-6207.CAPR-11-0234","DOI":"10.1158\/1940-6207.CAPR-11-0234"},{"key":"6600_CR31","doi-asserted-by":"publisher","first-page":"25998","DOI":"10.1038\/srep25998","volume":"6","author":"M Wang","year":"2016","unstructured":"Wang M, Wu X, Chai F et al (2016) Plasma prolactin and breast cancer risk: a meta- analysis. Sci Rep 6:25998. https:\/\/doi.org\/10.1038\/srep25998","journal-title":"Sci Rep"},{"issue":"1","key":"6600_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1677\/JOE-10-0069","volume":"206","author":"S Bernichtein","year":"2010","unstructured":"Bernichtein S, Touraine P, Goffin V (2010) New concepts in prolactin biology. J Endocrinol 206(1):1\u201311. https:\/\/doi.org\/10.1677\/JOE-10-0069","journal-title":"J Endocrinol"},{"key":"6600_CR33","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.pharmthera.2017.05.009","volume":"179","author":"V Goffin","year":"2017","unstructured":"Goffin V (2017) Prolactin receptor targeting in breast and prostate cancers: new insights into an old challenge. Pharmacol Ther 179:111\u2013126. https:\/\/doi.org\/10.1016\/j.pharmthera.2017.05.009","journal-title":"Pharmacol Ther"},{"key":"6600_CR34","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.00996","volume":"2","author":"S Haricharan","year":"2013","unstructured":"Haricharan S, Dong J, Hein S et al (2013) Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy. Elife 2:e00996. https:\/\/doi.org\/10.7554\/eLife.00996","journal-title":"Elife"},{"issue":"2","key":"6600_CR35","doi-asserted-by":"publisher","first-page":"R81","DOI":"10.1530\/ERC-18-0429","volume":"26","author":"G Secreto","year":"2019","unstructured":"Secreto G, Girombelli A, Krogh V (2019) Androgen excess in breast cancer development: implications for prevention and treatment. Endocr Relat Cancer 26(2):R81\u2013R94. https:\/\/doi.org\/10.1530\/ERC-18-0429","journal-title":"Endocr Relat Cancer"},{"issue":"7","key":"6600_CR36","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1158\/1940-6207.CAPR-11-0110","volume":"4","author":"PG Morris","year":"2011","unstructured":"Morris PG, Hudis CA, Giri D et al (2011) Inflammation and increased aromatase expression occur in the breast tissue of obese women with breast cancer. Cancer Prev Res (Phila) 4(7):1021\u20131029. https:\/\/doi.org\/10.1158\/1940-6207.CAPR-11-0110","journal-title":"Cancer Prev Res (Phila)"},{"issue":"1","key":"6600_CR37","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s13058-016-0791-4","volume":"19","author":"M Mullooly","year":"2017","unstructured":"Mullooly M, Yang HP, Falk RT et al (2017) Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients. Breast Cancer Res 19(1):8. https:\/\/doi.org\/10.1186\/s13058-016-0791-4","journal-title":"Breast Cancer Res"},{"issue":"2","key":"6600_CR38","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1158\/1940-6207.CAPR-17-0245","volume":"11","author":"JM Carter","year":"2018","unstructured":"Carter JM, Hoskin TL, Pena MA et al (2018) Macrophagic \u201ccrown-like structures\u201d are associated with an increased risk of breast cancer in benign breast disease. Cancer Prev Res (Phila) 11(2):113\u2013119. https:\/\/doi.org\/10.1158\/1940-6207.CAPR-17-0245","journal-title":"Cancer Prev Res (Phila)"},{"key":"6600_CR39","doi-asserted-by":"publisher","first-page":"573","DOI":"10.3389\/fendo.2020.00573","volume":"11","author":"M Chen","year":"2020","unstructured":"Chen M, Yang Y, Xu K et al (2020) androgen receptor in breast cancer: from bench to bedside. Front Endocrinol (Lausanne) 11:573. https:\/\/doi.org\/10.3389\/fendo.2020.00573","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5\u20136","key":"6600_CR40","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/s12672-016-0265-2","volume":"7","author":"H Oh","year":"2016","unstructured":"Oh H, Khodr ZG, Sherman ME et al (2016) Relation of serum estrogen metabolites with terminal duct lobular unit involution among women undergoing diagnostic image-guided breast biopsy. Horm Cancer 7(5\u20136):305\u2013315. https:\/\/doi.org\/10.1007\/s12672-016-0265-2","journal-title":"Horm Cancer"},{"issue":"2","key":"6600_CR41","doi-asserted-by":"publisher","first-page":"R34","DOI":"10.1186\/bcr3416","volume":"15","author":"RT Falk","year":"2013","unstructured":"Falk RT, Brinton LA, Dorgan JF et al (2013) Relationship of serum estrogens and estrogen metabolites to postmenopausal breast cancer risk: a nested case-control study. Breast Cancer Res 15(2):R34. https:\/\/doi.org\/10.1186\/bcr3416","journal-title":"Breast Cancer Res"},{"issue":"5","key":"6600_CR42","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1038\/s41591-021-01343-4","volume":"27","author":"J van der Laak","year":"2021","unstructured":"van der Laak J, Litjens G, Ciompi F (2021) Deep learning in histopathology: the path to the clinic. Nat Med 27(5):775\u2013784. https:\/\/doi.org\/10.1038\/s41591-021-01343-4","journal-title":"Nat Med"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-022-06600-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10549-022-06600-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-022-06600-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T15:08:00Z","timestamp":1654355280000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10549-022-06600-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,3]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["6600"],"URL":"https:\/\/doi.org\/10.1007\/s10549-022-06600-9","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,3]]},"assertion":[{"value":"17 January 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}