{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T22:07:01Z","timestamp":1780524421510,"version":"3.54.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T00:00:00Z","timestamp":1656979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T00:00:00Z","timestamp":1656979200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100009780","name":"Region Sk\u00e5ne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007436","name":"Familjen Erling-Perssons Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007436","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2020-01491"],"award-info":[{"award-number":["2020-01491"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006738","name":"Medicinska Fakulteten, Lunds Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006738","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Governmental Funding of Clinical Research within the National Health Service","award":["ALF young researcher Ida Skarping"],"award-info":[{"award-number":["ALF young researcher Ida Skarping"]}]},{"DOI":"10.13039\/501100003252","name":"Lund University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003252","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The need for sentinel lymph node biopsy (SLNB) in clinically node-negative (cN0) patients is currently questioned. Our objective was to investigate the cost-effectiveness of a preoperative noninvasive lymph node staging (NILS) model (an artificial neural network model) for predicting pathological nodal status in patients with cN0 breast cancer (BC).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A health-economic decision-analytic model was developed to evaluate the utility of the NILS model in reducing the proportion of cN0 patients with low predicted risk undergoing SLNB. The model used information from a national registry and published studies, and three sensitivity\/specificity scenarios of the NILS model were evaluated. Subgroup analysis explored the outcomes of breast-conserving surgery (BCS) or mastectomy. The results are presented as cost (\u20ac) and quality-adjusted life years (QALYs) per 1000 patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>All three scenarios of the NILS model reduced total costs (\u2013\u20ac93,244 to \u2013\u20ac398,941 per 1000 patients). The overall health benefit allowing for the impact of SLNB complications was a net health gain (7.0\u201326.9 QALYs per 1000 patients). Sensitivity analyses disregarding reduced quality of life from lymphedema showed a small loss in total health benefits (0.4\u20134.0 QALYs per 1000 patients) because of the reduction in total life years (0.6\u20136.5 life years per 1000 patients) after reduced adjuvant treatment. Subgroup analyses showed greater cost reductions and QALY gains in patients undergoing BCS.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Implementing the NILS model to identify patients with low risk for nodal metastases was associated with substantial cost reductions and likely overall health gains, especially in patients undergoing BCS.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10549-022-06636-x","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T19:02:46Z","timestamp":1657047766000},"page":"577-586","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The implementation of a noninvasive lymph node staging (NILS) preoperative prediction model is cost effective in primary breast cancer"],"prefix":"10.1007","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1265-8649","authenticated-orcid":false,"given":"Ida","family":"Skarping","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3732-4522","authenticated-orcid":false,"given":"Kristoffer","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7932-3982","authenticated-orcid":false,"given":"Looket","family":"Dihge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3715-003X","authenticated-orcid":false,"given":"Adam","family":"Fridhammar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1145-4297","authenticated-orcid":false,"given":"Mattias","family":"Ohlsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8597-9224","authenticated-orcid":false,"given":"Linnea","family":"Huss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8862-1845","authenticated-orcid":false,"given":"P\u00e4r-Ola","family":"Bendahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2325-5634","authenticated-orcid":false,"given":"Katarina","family":"Steen Carlsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7515-3130","authenticated-orcid":false,"given":"Lisa","family":"Ryd\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,7,5]]},"reference":[{"issue":"12","key":"6636_CR1","doi-asserted-by":"publisher","first-page":"3615","DOI":"10.31557\/APJCP.2018.19.12.3615","volume":"19","author":"A Rezvani","year":"2018","unstructured":"Rezvani A, Zahergivar A, Iranpour P, Akrami M, Kazemi S (2018) Diagnostic accuracy of axillary ultrasonography compared with intra-operative pathological findings in patients with breast cancer. Asian Pac J Cancer Prev 19(12):3615\u20133621. https:\/\/doi.org\/10.31557\/APJCP.2018.19.12.3615","journal-title":"Asian Pac J Cancer Prev"},{"issue":"1","key":"6636_CR2","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s10549-021-06283-8","volume":"189","author":"I Skarping","year":"2021","unstructured":"Skarping I, Fornvik D, Zackrisson S, Borgquist S, Ryden L (2021) Predicting pathological axillary lymph node status with ultrasound following neoadjuvant therapy for breast cancer. Breast Cancer Res Treat 189(1):131\u2013144. https:\/\/doi.org\/10.1007\/s10549-021-06283-8","journal-title":"Breast Cancer Res Treat"},{"issue":"27","key":"6636_CR3","doi-asserted-by":"publisher","first-page":"3056","DOI":"10.1200\/JCO.21.00934","volume":"39","author":"M Brackstone","year":"2021","unstructured":"Brackstone M, Baldassarre FG, Perera FE, Cil T, Chavez Mac Gregor M, Dayes IS, Engel J, Horton JK, King TA, Kornecki A, George R, SenGupta SK, Spears PA, Eisen AF (2021) Management of the axilla in early-stage breast cancer: ontario health (Cancer Care Ontario) and ASCO guideline. J Clin Oncol 39(27):3056\u20133082. https:\/\/doi.org\/10.1200\/JCO.21.00934","journal-title":"J Clin Oncol"},{"issue":"11","key":"6636_CR4","doi-asserted-by":"publisher","first-page":"5950","DOI":"10.1245\/s10434-021-09839-6","volume":"28","author":"E McKevitt","year":"2021","unstructured":"McKevitt E, Cheifetz R, DeVries K, Laws A, Warburton R, Gondara L, Lohrisch C, Nichol A (2021) Sentinel node biopsy should not be routine in older patients with ER-Positive HER2-Negative breast cancer who are willing and able to take hormone therapy. Ann Surg Oncol 28(11):5950\u20135957. https:\/\/doi.org\/10.1245\/s10434-021-09839-6","journal-title":"Ann Surg Oncol"},{"issue":"10","key":"6636_CR5","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1002\/bjs.5052","volume":"92","author":"L Bergkvist","year":"2005","unstructured":"Bergkvist L, Frisell J, Swedish Breast Cancer G, Swedish Society of Breast Surgeons (2005) Multicentre validation study of sentinel node biopsy for staging in breast cancer. Br J Surg 92(10):1221\u20131224. https:\/\/doi.org\/10.1002\/bjs.5052","journal-title":"Br J Surg"},{"issue":"4","key":"6636_CR6","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1002\/bjs.9401","volume":"101","author":"H Sackey","year":"2014","unstructured":"Sackey H, Magnuson A, Sandelin K, Liljegren G, Bergkvist L, Fulep Z, Celebioglu F, Frisell J (2014) Arm lymphoedema after axillary surgery in women with invasive breast cancer. Br J Surg 101(4):390\u2013397. https:\/\/doi.org\/10.1002\/bjs.9401","journal-title":"Br J Surg"},{"issue":"13","key":"6636_CR7","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1001\/jama.2013.277804","volume":"310","author":"R Rao","year":"2013","unstructured":"Rao R, Euhus D, Mayo HG, Balch C (2013) Axillary node interventions in breast cancer: a systematic review. JAMA 310(13):1385\u20131394. https:\/\/doi.org\/10.1001\/jama.2013.277804","journal-title":"JAMA"},{"issue":"10","key":"6636_CR8","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1001\/jama.2017.11470","volume":"318","author":"AE Giuliano","year":"2017","unstructured":"Giuliano AE, Ballman KV, McCall L, Beitsch PD, Brennan MB, Kelemen PR, Ollila DW, Hansen NM, Whitworth PW, Blumencranz PW, Leitch AM, Saha S, Hunt KK, Morrow M (2017) Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis: The ACOSOG Z0011 (Alliance) randomized clinical trial. JAMA 318(10):918\u2013926. https:\/\/doi.org\/10.1001\/jama.2017.11470","journal-title":"JAMA"},{"issue":"2","key":"6636_CR9","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1055\/s-0042-122853","volume":"77","author":"T Reimer","year":"2017","unstructured":"Reimer T, Stachs A, Nekljudova V, Loibl S, Hartmann S, Wolter K, Hildebrandt G, Gerber B (2017) Restricted axillary staging in clinically and sonographically node-negative early invasive breast cancer (c\/iT1-2) in the context of breast conserving therapy: first results following commencement of the Intergroup-Sentinel-Mamma (INSEMA) trial. Geburtshilfe Frauenheilkd 77(2):149\u2013157. https:\/\/doi.org\/10.1055\/s-0042-122853","journal-title":"Geburtshilfe Frauenheilkd"},{"issue":"5","key":"6636_CR10","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1016\/j.breast.2012.06.013","volume":"21","author":"O Gentilini","year":"2012","unstructured":"Gentilini O, Veronesi U (2012) Abandoning sentinel lymph node biopsy in early breast cancer? A new trial in progress at the European Institute of Oncology of Milan (SOUND: Sentinel node vs Observation after axillary UltraSouND). Breast 21(5):678\u2013681. https:\/\/doi.org\/10.1016\/j.breast.2012.06.013","journal-title":"Breast"},{"issue":"1","key":"6636_CR11","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1186\/s12885-017-3443-x","volume":"17","author":"LM van Roozendaal","year":"2017","unstructured":"van Roozendaal LM, Vane MLG, van Dalen T, van der Hage JA, Strobbe LJA, Boersma LJ, Linn SC, Lobbes MBI, Poortmans PMP, Tjan-Heijnen VCG, Van de Vijver K, de Vries J, Westenberg AH, Kessels AGH, de Wilt JHW, Smidt ML (2017) Clinically node negative breast cancer patients undergoing breast conserving therapy, sentinel lymph node procedure versus follow-up: a Dutch randomized controlled multicentre trial (BOOG 2013\u201308). BMC Cancer 17(1):459. https:\/\/doi.org\/10.1186\/s12885-017-3443-x","journal-title":"BMC Cancer"},{"issue":"1","key":"6636_CR12","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1186\/s12885-019-5827-6","volume":"19","author":"L Dihge","year":"2019","unstructured":"Dihge L, Ohlsson M, Eden P, Bendahl PO, Ryden L (2019) Artificial neural network models to predict nodal status in clinically node-negative breast cancer. BMC Cancer 19(1):610. https:\/\/doi.org\/10.1186\/s12885-019-5827-6","journal-title":"BMC Cancer"},{"key":"6636_CR13","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12030582","author":"I Skarping","year":"2022","unstructured":"Skarping I, Dihge L, Bendahl PO, Huss L, Ellbrant J, Ohlsson M, Ryden L (2022) The NILS study protocol: a retrospective validation study of an artificial neural network based preoperative decision-making tool for noninvasive lymph node staging in women with primary breast cancer (ISRCTN14341750). Diagnostics (Basel). https:\/\/doi.org\/10.3390\/diagnostics12030582","journal-title":"Diagnostics (Basel)"},{"issue":"7","key":"6636_CR14","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1007\/s40273-017-0509-1","volume":"35","author":"MJ Ij","year":"2017","unstructured":"Ij MJ, Koffijberg H, Fenwick E, Krahn M (2017) Emerging use of early health technology assessment in medical product development: a scoping review of the literature. Pharmacoeconomics 35(7):727\u2013740. https:\/\/doi.org\/10.1007\/s40273-017-0509-1","journal-title":"Pharmacoeconomics"},{"issue":"4","key":"6636_CR15","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1017\/S0266462308080616","volume":"24","author":"S Hartz","year":"2008","unstructured":"Hartz S, John J (2008) Contribution of economic evaluation to decision making in early phases of product development: a methodological and empirical review. Int J Technol Assess Health Care 24(4):465\u2013472. https:\/\/doi.org\/10.1017\/S0266462308080616","journal-title":"Int J Technol Assess Health Care"},{"key":"6636_CR16","unstructured":"Br\u00f6stcancer - nationellt v\u00e5rdprogram (Clinical Practice Guidelines on Breast Cancer) (2020). Swedish Breast Cancer Group, 220121. https:\/\/kunskapsbanken.cancercentrum.se\/globalassets\/cancerdiagnoser\/brost\/vardprogram\/nationellt-vardprogram-brostcancer.pdf"},{"issue":"1","key":"6636_CR17","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/s00268-012-1788-5","volume":"37","author":"S Majid","year":"2013","unstructured":"Majid S, Tengrup I, Manjer J (2013) Clinical assessment of axillary lymph nodes and tumor size in breast cancer compared with histopathological examination: a population-based analysis of 2,537 women. World J Surg 37(1):67\u201371. https:\/\/doi.org\/10.1007\/s00268-012-1788-5","journal-title":"World J Surg"},{"issue":"6","key":"6636_CR18","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.1245\/s10434-018-6410-0","volume":"25","author":"BK Killelea","year":"2018","unstructured":"Killelea BK, Long JB, Dang W, Mougalian SS, Evans SB, Gross CP, Wang SY (2018) Associations between sentinel lymph node biopsy and complications for patients with ductal carcinoma in situ. Ann Surg Oncol 25(6):1521\u20131529. https:\/\/doi.org\/10.1245\/s10434-018-6410-0","journal-title":"Ann Surg Oncol"},{"issue":"1","key":"6636_CR19","doi-asserted-by":"publisher","first-page":"55","DOI":"10.3322\/caac.21253","volume":"65","author":"SF Shaitelman","year":"2015","unstructured":"Shaitelman SF, Cromwell KD, Rasmussen JC, Stout NL, Armer JM, Lasinski BB, Cormier JN (2015) Recent progress in the treatment and prevention of cancer-related lymphedema. CA Cancer J Clin 65(1):55\u201381. https:\/\/doi.org\/10.3322\/caac.21253","journal-title":"CA Cancer J Clin"},{"issue":"2","key":"6636_CR20","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1007\/s10549-018-4820-0","volume":"171","author":"Y Andersson","year":"2018","unstructured":"Andersson Y, Bergkvist L, Frisell J, de Boniface J (2018) Long-term breast cancer survival in relation to the metastatic tumor burden in axillary lymph nodes. Breast Cancer Res Treat 171(2):359\u2013369. https:\/\/doi.org\/10.1007\/s10549-018-4820-0","journal-title":"Breast Cancer Res Treat"},{"issue":"9503","key":"6636_CR21","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1016\/S0140-6736(05)67887-7","volume":"366","author":"M Clarke","year":"2005","unstructured":"Clarke M, Collins R, Darby S, Davies C, Elphinstone P, Evans V, Godwin J, Gray R, Hicks C, James S, MacKinnon E, McGale P, McHugh T, Peto R, Taylor C, Wang Y, Early Breast Cancer Trialists\u2019 Collaborative Group (2005) Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 366(9503):2087\u20132106. https:\/\/doi.org\/10.1016\/S0140-6736(05)67887-7","journal-title":"Lancet"},{"issue":"9814","key":"6636_CR22","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1016\/S0140-6736(11)61625-5","volume":"379","author":"R Peto","year":"2012","unstructured":"Peto R, Davies C, Godwin J, Gray R, Pan HC, Clarke M, Cutter D, Darby S, McGale P, Taylor C, Wang YC, Bergh J, Di Leo A, Albain K, Swain S, Piccart M, Pritchard K, Early Breast Cancer Trialists\u2019 Collaborative Group (2012) Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials. Lancet 379(9814):432\u2013444. https:\/\/doi.org\/10.1016\/S0140-6736(11)61625-5","journal-title":"Lancet"},{"issue":"9869","key":"6636_CR23","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1016\/S0140-6736(12)61963-1","volume":"381","author":"C Davies","year":"2013","unstructured":"Davies C, Pan H, Godwin J, Gray R, Arriagada R, Raina V, Abraham M, Medeiros Alencar VH, Badran A, Bonfill X, Bradbury J, Clarke M, Collins R, Davis SR, Delmestri A, Forbes JF, Haddad P, Hou MF, Inbar M, Khaled H, Kielanowska J, Kwan WH, Mathew BS, Mittra I, Muller B, Nicolucci A, Peralta O, Pernas F, Petruzelka L, Pienkowski T, Radhika R, Rajan B, Rubach MT, Tort S, Urrutia G, Valentini M, Wang Y, Peto R, Adjuvant Tamoxifen: Longer Against Shorter Collaborative Group (2013) Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial. Lancet 381(9869):805\u2013816. https:\/\/doi.org\/10.1016\/S0140-6736(12)61963-1","journal-title":"Lancet"},{"issue":"3","key":"6636_CR24","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","volume":"16","author":"G EuroQol","year":"1990","unstructured":"EuroQol G (1990) EuroQol\u2013a new facility for the measurement of health-related quality of life. Health Policy 16(3):199\u2013208. https:\/\/doi.org\/10.1016\/0168-8510(90)90421-9","journal-title":"Health Policy"},{"key":"6636_CR25","volume-title":"Health-related quality of life in Stockholm county 2002 [H\u00e4lsorelaterad livskvalitet i Stockholms l\u00e4n 2002]","author":"K Burstr\u00f6m","year":"2002","unstructured":"Burstr\u00f6m K, Rehnberg C (2002) Health-related quality of life in Stockholm county 2002 [H\u00e4lsorelaterad livskvalitet i Stockholms l\u00e4n 2002]. Stockholms l\u00e4ns landsting, Stockholm"},{"issue":"1","key":"6636_CR26","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1093\/jnci\/djr484","volume":"104","author":"PS Hall","year":"2012","unstructured":"Hall PS, McCabe C, Stein RC, Cameron D (2012) Economic evaluation of genomic test-directed chemotherapy for early-stage lymph node-positive breast cancer. J Natl Cancer Inst 104(1):56\u201366. https:\/\/doi.org\/10.1093\/jnci\/djr484","journal-title":"J Natl Cancer Inst"},{"issue":"3","key":"6636_CR27","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1111\/wrr.12529","volume":"25","author":"K Herberger","year":"2017","unstructured":"Herberger K, Blome C, Heyer K, Ellis F, Munter KC, Augustin M (2017) Quality of life in patients with primary and secondary lymphedema in the community. Wound Repair Regen 25(3):466\u2013473. https:\/\/doi.org\/10.1111\/wrr.12529","journal-title":"Wound Repair Regen"},{"issue":"15","key":"6636_CR28","doi-asserted-by":"publisher","first-page":"3722","DOI":"10.1002\/cncr.25068","volume":"116","author":"AL Cheville","year":"2010","unstructured":"Cheville AL, Almoza M, Courmier JN, Basford JR (2010) A prospective cohort study defining utilities using time trade-offs and the Euroqol-5D to assess the impact of cancer-related lymphedema. Cancer 116(15):3722\u20133731. https:\/\/doi.org\/10.1002\/cncr.25068","journal-title":"Cancer"},{"key":"6636_CR29","unstructured":"Tandv\u00e5rds- och l\u00e4kemedelsf\u00f6rm\u00e5nsverkets allm\u00e4nna r\u00e5d. The Dental and Pharmaceutical Benefits Agency, www.tlv.se 220121"},{"issue":"2","key":"6636_CR30","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1007\/s10549-020-05768-2","volume":"183","author":"AM McEvoy","year":"2020","unstructured":"McEvoy AM, Poplack S, Nickel K, Olsen MA, Ademuyiwa F, Zoberi I, Odom E, Yu J, Chang SH, Gillanders WE (2020) Cost-effectiveness analyses demonstrate that observation is superior to sentinel lymph node biopsy for postmenopausal women with HR + breast cancer and negative axillary ultrasound. Breast Cancer Res Treat 183(2):251\u2013262. https:\/\/doi.org\/10.1007\/s10549-020-05768-2","journal-title":"Breast Cancer Res Treat"},{"key":"6636_CR31","unstructured":"National Quality Register for Breast Cancer (INCA) Yearly report 2019 (interactive) (2020). 211115"},{"issue":"10","key":"6636_CR32","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1016\/S1470-2045(07)70278-4","volume":"8","author":"DN Krag","year":"2007","unstructured":"Krag DN, Anderson SJ, Julian TB, Brown AM, Harlow SP, Ashikaga T, Weaver DL, Miller BJ, Jalovec LM, Frazier TG, Noyes RD, Robidoux A, Scarth HM, Mammolito DM, McCready DR, Mamounas EP, Costantino JP, Wolmark N, National Surgical Adjuvant B, Bowel P (2007) Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial. Lancet Oncol 8(10):881\u2013888. https:\/\/doi.org\/10.1016\/S1470-2045(07)70278-4","journal-title":"Lancet Oncol"},{"issue":"9","key":"6636_CR33","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1007\/s00268-012-1623-z","volume":"36","author":"S Pesek","year":"2012","unstructured":"Pesek S, Ashikaga T, Krag LE, Krag D (2012) The false-negative rate of sentinel node biopsy in patients with breast cancer: a meta-analysis. World J Surg 36(9):2239\u20132251. https:\/\/doi.org\/10.1007\/s00268-012-1623-z","journal-title":"World J Surg"},{"issue":"2","key":"6636_CR34","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1159\/000360411","volume":"9","author":"T Reimer","year":"2014","unstructured":"Reimer T, Hartmann S, Stachs A, Gerber B (2014) Local treatment of the axilla in early breast cancer: concepts from the national surgical adjuvant breast and bowel project B-04 to the planned intergroup sentinel mamma trial. Breast Care (Basel) 9(2):87\u201395. https:\/\/doi.org\/10.1159\/000360411","journal-title":"Breast Care (Basel)"},{"issue":"1","key":"6636_CR35","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s11764-012-0247-5","volume":"7","author":"AL Pusic","year":"2013","unstructured":"Pusic AL, Cemal Y, Albornoz C, Klassen A, Cano S, Sulimanoff I, Hernandez M, Massey M, Cordeiro P, Morrow M, Mehrara B (2013) Quality of life among breast cancer patients with lymphedema: a systematic review of patient-reported outcome instruments and outcomes. J Cancer Surviv 7(1):83\u201392. https:\/\/doi.org\/10.1007\/s11764-012-0247-5","journal-title":"J Cancer Surviv"},{"issue":"3","key":"6636_CR36","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.critrevonc.2014.06.004","volume":"92","author":"NR Taghian","year":"2014","unstructured":"Taghian NR, Miller CL, Jammallo LS, O\u2019Toole J, Skolny MN (2014) Lymphedema following breast cancer treatment and impact on quality of life: a review. Crit Rev Oncol Hematol 92(3):227\u2013234. https:\/\/doi.org\/10.1016\/j.critrevonc.2014.06.004","journal-title":"Crit Rev Oncol Hematol"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-022-06636-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10549-022-06636-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-022-06636-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T04:27:00Z","timestamp":1657859220000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10549-022-06636-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,5]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["6636"],"URL":"https:\/\/doi.org\/10.1007\/s10549-022-06636-x","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,5]]},"assertion":[{"value":"21 January 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 July 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"N\/A.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"N\/A.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}