{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T15:08:55Z","timestamp":1793718535324,"version":"4.6.1"},"reference-count":141,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"PureTech Health plc","id":[{"id":"https:\/\/ror.org\/056qtgk16","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Breast cancer-related lymphedema (BCRL) represents a lifelong risk for breast cancer survivors and once acquired becomes a lifelong burden. This review summarizes current BCRL prevention and treatment strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>Risk factors for BCRL have been extensively studied and their identification has affected breast cancer treatment practice, with sentinel lymph node removal now standard of care for patients with early stage breast cancer without sentinel lymph node metastases. Early surveillance and timely management aim to reduce BCRL incidence and progression, and are further facilitated by patient education, which many breast cancer survivors report not having adequately received. Surgical approaches to BCRL prevention include axillary reverse mapping, lymphatic microsurgical preventative healing (LYMPHA) and Simplified LYMPHA (SLYMPHA). Complete decongestive therapy (CDT) remains the standard of care for patients with BCRL. Among CDT components, facilitating manual lymphatic drainage (MLD) using indocyanine green fluorescence lymphography has been proposed. Intermittent pneumatic compression, nonpneumatic active compression devices, and low-level laser therapy appear promising in lymphedema management. Reconstructive microsurgical techniques such as lymphovenous anastomosis and vascular lymph node transfer are growing surgical considerations for patients as well as liposuction-based procedures for addressing fatty fibrosis formation from chronic lymphedema. Long-term self-management adherence remains problematic, and lack of diagnosis and measurement consensus precludes a comparison of outcomes. Currently, no pharmacological approaches have proven successful.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Progress in prevention and treatment of BCRL continues, requiring advances in early diagnosis, patient education, expert consensus and novel treatments designed for lymphatic rehabilitation following insults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10549-023-06947-7","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T01:02:53Z","timestamp":1682557373000},"page":"1-14","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":160,"title":["Advances in the prevention and treatment of breast cancer-related lymphedema"],"prefix":"10.1007","volume":"200","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4656-6539","authenticated-orcid":false,"given":"Paula M. C.","family":"Donahue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrien","family":"MacKenzie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Filipovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Koelmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"key":"6947_CR1","doi-asserted-by":"publisher","first-page":"1800","DOI":"10.1177\/0193945917744351","volume":"40","author":"PL Ostby","year":"2018","unstructured":"Ostby PL, Armer JM, Smith K, Stewart BR (2018) Patient perceptions of barriers to self-management of breast cancer-related lymphedema. West J Nurs Res 40:1800\u20131817. https:\/\/doi.org\/10.1177\/0193945917744351","journal-title":"West J Nurs Res"},{"key":"6947_CR2","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s10549-018-4902-z","volume":"172","author":"F Sun","year":"2018","unstructured":"Sun F, Hall A, Tighe MP, Brunelle CL, Sayegh HE, Gillespie TC, Daniell KM, Taghian AG (2018) Perometry versus simulated circumferential tape measurement for the detection of breast cancer-related lymphedema. Breast Cancer Res Treat 172:83\u201391. https:\/\/doi.org\/10.1007\/s10549-018-4902-z","journal-title":"Breast Cancer Res Treat"},{"key":"6947_CR3","doi-asserted-by":"publisher","first-page":"E18","DOI":"10.1097\/NCC.0b013e31821404c0","volume":"35","author":"SH Ridner","year":"2012","unstructured":"Ridner SH, Bonner CM, Deng J, Sinclair VG (2012) Voices from the shadows: living with lymphedema. Cancer Nurs 35:E18-26. https:\/\/doi.org\/10.1097\/NCC.0b013e31821404c0","journal-title":"Cancer Nurs"},{"key":"6947_CR4","doi-asserted-by":"publisher","first-page":"345","DOI":"10.2147\/BCTT.S87854","volume":"7","author":"MR Fu","year":"2015","unstructured":"Fu MR, Axelrod D, Cleland CM, Qiu Z, Guth AA, Kleinman R, Scagliola J, Haber J (2015) Symptom report in detecting breast cancer-related lymphedema. Breast Cancer (Dove Med Press) 7:345\u2013352. https:\/\/doi.org\/10.2147\/BCTT.S87854","journal-title":"Breast Cancer (Dove Med Press)"},{"key":"6947_CR5","doi-asserted-by":"publisher","first-page":"5689","DOI":"10.1200\/JCO.2008.16.4731","volume":"26","author":"RL Ahmed","year":"2008","unstructured":"Ahmed RL, Prizment A, Lazovich D, Schmitz KH, Folsom AR (2008) Lymphedema and quality of life in breast cancer survivors: the Iowa Women\u2019s Health Study. J Clin Oncol 26:5689\u20135696. https:\/\/doi.org\/10.1200\/JCO.2008.16.4731","journal-title":"J Clin Oncol"},{"key":"6947_CR6","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.soncn.2012.11.007","volume":"29","author":"MR Fu","year":"2013","unstructured":"Fu MR, Kang Y (2013) Psychosocial impact of living with cancer-related lymphedema. Semin Oncol Nurs 29:50\u201360. https:\/\/doi.org\/10.1016\/j.soncn.2012.11.007","journal-title":"Semin Oncol Nurs"},{"key":"6947_CR7","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1007\/s00520-019-05101-8","volume":"28","author":"T De Vrieze","year":"2020","unstructured":"De Vrieze T, Nevelsteen I, Thomis S, De Groef A, Tjalma WAA, Gebruers N, Devoogdt N (2020) What are the economic burden and costs associated with the treatment of breast cancer-related lymphoedema? A systematic review. Support Care Cancer 28:439\u2013449. https:\/\/doi.org\/10.1007\/s00520-019-05101-8","journal-title":"Support Care Cancer"},{"key":"6947_CR8","doi-asserted-by":"publisher","first-page":"5164","DOI":"10.1002\/cam4.3188","volume":"9","author":"SH Ridner","year":"2020","unstructured":"Ridner SH, Shah C, Boyages J, Koelmeyer L, Ajkay N, DeSnyder SM, McLaughlin SA, Dietrich MS (2020) L-Dex, arm volume, and symptom trajectories 24 months after breast cancer surgery. Cancer Med 9:5164\u20135173. https:\/\/doi.org\/10.1002\/cam4.3188","journal-title":"Cancer Med"},{"key":"6947_CR9","unstructured":"American Cancer Society (2022) Key statistics for breast cancer. https:\/\/www.cancer.org\/cancer\/breast-cancer\/about\/how-common-is-breast-cancer.html. Accessed 16 Jan 2023"},{"key":"6947_CR10","doi-asserted-by":"publisher","first-page":"55","DOI":"10.3322\/caac.21253","volume":"65","author":"SF Shaitelman","year":"2015","unstructured":"Shaitelman SF, Cromwell KD, Rasmussen JC, Stout NL, Armer JM, Lasinski BB, Cormier JN (2015) Recent progress in the treatment and prevention of cancer-related lymphedema. CA Cancer J Clin 65:55\u201381. https:\/\/doi.org\/10.3322\/caac.21253","journal-title":"CA Cancer J Clin"},{"key":"6947_CR11","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/S1470-2045(13)70076-7","volume":"14","author":"T DiSipio","year":"2013","unstructured":"DiSipio T, Rye S, Newman B, Hayes S (2013) Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis. Lancet Oncol 14:500\u2013515. https:\/\/doi.org\/10.1016\/S1470-2045(13)70076-7","journal-title":"Lancet Oncol"},{"key":"6947_CR12","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.breast.2016.04.011","volume":"28","author":"SL Kilbreath","year":"2016","unstructured":"Kilbreath SL, Refshauge KM, Beith JM, Ward LC, Ung OA, Dylke ES, French JR, Yee J, Koelmeyer L, Gaitatzis K (2016) Risk factors for lymphoedema in women with breast cancer: a large prospective cohort. Breast 28:29\u201336. https:\/\/doi.org\/10.1016\/j.breast.2016.04.011","journal-title":"Breast"},{"key":"6947_CR13","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1007\/s00520-018-4388-6","volume":"27","author":"IW Penn","year":"2019","unstructured":"Penn IW, Chang YC, Chuang E, Chen CM, Chung CF, Kuo CY, Chuang TY (2019) Risk factors and prediction model for persistent breast-cancer-related lymphedema: a 5-year cohort study. Support Care Cancer 27:991\u20131000. https:\/\/doi.org\/10.1007\/s00520-018-4388-6","journal-title":"Support Care Cancer"},{"key":"6947_CR14","doi-asserted-by":"publisher","first-page":"2734","DOI":"10.1158\/1055-9965.EPI-09-1245","volume":"19","author":"SA Norman","year":"2010","unstructured":"Norman SA, Localio AR, Kallan MJ, Weber AL, Torpey HA, Potashnik SL, Miller LT, Fox KR, DeMichele A, Solin LJ (2010) Risk factors for lymphedema after breast cancer treatment. Cancer Epidemiol Biomark Prev 19:2734\u20132746. https:\/\/doi.org\/10.1158\/1055-9965.EPI-09-1245","journal-title":"Cancer Epidemiol Biomark Prev"},{"key":"6947_CR15","doi-asserted-by":"publisher","first-page":"1959","DOI":"10.1245\/s10434-009-0452-2","volume":"16","author":"RJ Tsai","year":"2009","unstructured":"Tsai RJ, Dennis LK, Lynch CF, Snetselaar LG, Zamba GK, Scott-Conner C (2009) The risk of developing arm lymphedema among breast cancer survivors: a meta-analysis of treatment factors. Ann Surg Oncol 16:1959\u20131972. https:\/\/doi.org\/10.1245\/s10434-009-0452-2","journal-title":"Ann Surg Oncol"},{"key":"6947_CR16","doi-asserted-by":"publisher","first-page":"379","DOI":"10.21037\/gs.2017.11.04","volume":"7","author":"TC Gillespie","year":"2018","unstructured":"Gillespie TC, Sayegh HE, Brunelle CL, Daniell KM, Taghian AG (2018) Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments. Gland Surg 7:379\u2013403. https:\/\/doi.org\/10.21037\/gs.2017.11.04","journal-title":"Gland Surg"},{"key":"6947_CR17","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1001\/archsurg.2010.231","volume":"145","author":"ML Kwan","year":"2010","unstructured":"Kwan ML, Darbinian J, Schmitz KH, Citron R, Partee P, Kutner SE, Kushi LH (2010) Risk factors for lymphedema in a prospective breast cancer survivorship study: the Pathways Study. Arch Surg (Chicago, Ill.: 1950) 145:1055\u20131063. https:\/\/doi.org\/10.1001\/archsurg.2010.231","journal-title":"Arch Surg (Chicago, Ill.: 1950)"},{"key":"6947_CR18","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1007\/s12609-013-0105-0","volume":"5","author":"JM Armer","year":"2013","unstructured":"Armer JM, Hulett JM, Bernas M, Ostby P, Stewart BR, Cormier JN (2013) Best practice guidelines in assessment, risk reduction, management, and surveillance for post-breast cancer lymphedema. Curr Breast Cancer Rep 5:134\u2013144. https:\/\/doi.org\/10.1007\/s12609-013-0105-0","journal-title":"Curr Breast Cancer Rep"},{"key":"6947_CR19","doi-asserted-by":"publisher","first-page":"e2024373","DOI":"10.1001\/jamanetworkopen.2020.24373","volume":"3","author":"JYY Kwan","year":"2020","unstructured":"Kwan JYY, Famiyeh P, Su J, Xu W, Kwan BYM, Jones JM, Chang E, Yip KW, Liu FF (2020) Development and validation of a risk model for breast cancer-related lymphedema. JAMA Netw Open 3:e2024373. https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.24373","journal-title":"JAMA Netw Open"},{"key":"6947_CR20","doi-asserted-by":"publisher","first-page":"3408","DOI":"10.1002\/cncr.34377","volume":"128","author":"LA Koelmeyer","year":"2022","unstructured":"Koelmeyer LA, Gaitatzis K, Dietrich MS, Shah CS, Boyages J, McLaughlin SA, Taback B, Stolldorf DP, Elder E, Hughes TM, French JR, Ngui N, Hsu JM, Moore A, Ridner SH (2022) Risk factors for breast cancer-related lymphedema in patients undergoing 3 years of prospective surveillance with intervention. Cancer 128:3408\u20133415. https:\/\/doi.org\/10.1002\/cncr.34377","journal-title":"Cancer"},{"key":"6947_CR21","doi-asserted-by":"publisher","first-page":"2341","DOI":"10.1200\/JCO.19.02896","volume":"38","author":"SA McLaughlin","year":"2020","unstructured":"McLaughlin SA, Brunelle CL, Taghian A (2020) Breast cancer-related lymphedema: risk factors, ccreening, management, and the impact of locoregional treatment. J Clin Oncol 38:2341\u20132350. https:\/\/doi.org\/10.1200\/JCO.19.02896","journal-title":"J Clin Oncol"},{"key":"6947_CR22","doi-asserted-by":"publisher","first-page":"3430","DOI":"10.1200\/JCO.20.00459","volume":"38","author":"GE Naoum","year":"2020","unstructured":"Naoum GE, Roberts S, Brunelle CL, Shui AM, Salama L, Daniell K, Gillespie T, Bucci L, Smith BL, Ho AY, Taghian AG (2020) Quantifying the impact of axillary surgery and nodal irradiation on breast cancer-related lymphedema and local tumor control: long-term results from a prospective screening trial. J Clin Oncol 38:3430\u20133438. https:\/\/doi.org\/10.1200\/JCO.20.00459","journal-title":"J Clin Oncol"},{"key":"6947_CR23","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1097\/PRS.0b013e31826d0faa","volume":"130","author":"A Card","year":"2012","unstructured":"Card A, Crosby MA, Liu J, Lindstrom WA, Lucci A, Chang DW (2012) Reduced incidence of breast cancer-related lymphedema following mastectomy and breast reconstruction versus mastectomy alone. Plast Reconstr Surg 130:1169\u20131178. https:\/\/doi.org\/10.1097\/PRS.0b013e31826d0faa","journal-title":"Plast Reconstr Surg"},{"key":"6947_CR24","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1097\/SLA.0000000000001128","volume":"263","author":"CL Miller","year":"2016","unstructured":"Miller CL, Colwell AS, Horick N, Skolny MN, Jammallo LS, O\u2019Toole JA, Shenouda MN, Sadek BT, Swaroop MN, Ferguson CM, Smith BL, Specht MC, Taghian AG (2016) Immediate implant reconstruction is associated with a reduced risk of lymphedema compared to mastectomy alone: a prospective cohort study. Ann Surg 263:399\u2013405. https:\/\/doi.org\/10.1097\/SLA.0000000000001128","journal-title":"Ann Surg"},{"key":"6947_CR25","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1200\/JCO.2016.71.0947","volume":"35","author":"GH Lyman","year":"2017","unstructured":"Lyman GH, Somerfield MR, Bosserman LD, Perkins CL, Weaver DL, Giuliano AE (2017) Sentinel lymph node biopsy for patients with early-stage breast cancer: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol 35:561\u2013564. https:\/\/doi.org\/10.1200\/JCO.2016.71.0947","journal-title":"J Clin Oncol"},{"key":"6947_CR26","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1093\/jnci\/93.2.96","volume":"93","author":"VS Erickson","year":"2001","unstructured":"Erickson VS, Pearson ML, Ganz PA, Adams J, Kahn KL (2001) Arm edema in breast cancer patients. J Natl Cancer Inst 93:96\u2013111. https:\/\/doi.org\/10.1093\/jnci\/93.2.96","journal-title":"J Natl Cancer Inst"},{"key":"6947_CR27","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1056\/NEJMoa1415340","volume":"373","author":"TJ Whelan","year":"2015","unstructured":"Whelan TJ, Olivotto IA, Parulekar WR, Ackerman I, Chua BH, Nabid A, Vallis KA, White JR, Rousseau P, Fortin A, Pierce LJ, Manchul L, Chafe S, Nolan MC, Craighead P, Bowen J, McCready DR, Pritchard KI, Gelmon K, Murray Y, Chapman JA, Chen BE, Levine MN, Investigators MAS (2015) Regional nodal irradiation in early-stage breast cancer. N Engl J Med 373:307\u2013316. https:\/\/doi.org\/10.1056\/NEJMoa1415340","journal-title":"N Engl J Med"},{"key":"6947_CR28","doi-asserted-by":"publisher","first-page":"2580","DOI":"10.1245\/s10434-012-2290-x","volume":"19","author":"JL Bevilacqua","year":"2012","unstructured":"Bevilacqua JL, Kattan MW, Changhong Y, Koifman S, Mattos IE, Koifman RJ, Bergmann A (2012) Nomograms for predicting the risk of arm lymphedema after axillary dissection in breast cancer. Ann Surg Oncol 19:2580\u20132589. https:\/\/doi.org\/10.1245\/s10434-012-2290-x","journal-title":"Ann Surg Oncol"},{"key":"6947_CR29","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.ijrobp.2018.08.036","volume":"103","author":"SGR McDuff","year":"2019","unstructured":"McDuff SGR, Mina AI, Brunelle CL, Salama L, Warren LEG, Abouegylah M, Swaroop M, Skolny MN, Asdourian M, Gillespie T, Daniell K, Sayegh HE, Naoum GE, Zheng H, Taghian AG (2019) Timing of lymphedema after treatment for breast cancer: when are patients most at risk? Int J Radiat Oncol Biol Phys 103:62\u201370. https:\/\/doi.org\/10.1016\/j.ijrobp.2018.08.036","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"6947_CR30","doi-asserted-by":"publisher","first-page":"e60164","DOI":"10.1371\/journal.pone.0060164","volume":"8","author":"C Miaskowski","year":"2013","unstructured":"Miaskowski C, Dodd M, Paul SM, West C, Hamolsky D, Abrams G, Cooper BA, Elboim C, Neuhaus J, Schmidt BL, Smoot B, Aouizerat BE (2013) Lymphatic and angiogenic candidate genes predict the development of secondary lymphedema following breast cancer surgery. PLoS ONE 8:e60164. https:\/\/doi.org\/10.1371\/journal.pone.0060164","journal-title":"PLoS ONE"},{"key":"6947_CR31","doi-asserted-by":"publisher","first-page":"5213","DOI":"10.1200\/JCO.2008.16.3725","volume":"26","author":"SA McLaughlin","year":"2008","unstructured":"McLaughlin SA, Wright MJ, Morris KT, Giron GL, Sampson MR, Brockway JP, Hurley KE, Riedel ER, Van Zee KJ (2008) Prevalence of lymphedema in women with breast cancer 5 years after sentinel lymph node biopsy or axillary dissection: objective measurements. J Clin Oncol 26:5213\u20135219. https:\/\/doi.org\/10.1200\/JCO.2008.16.3725","journal-title":"J Clin Oncol"},{"key":"6947_CR32","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1001\/jamaoncol.2022.1628","volume":"8","author":"G Montagna","year":"2022","unstructured":"Montagna G, Zhang J, Sevilimedu V, Charyn J, Abbate K, Gomez EA, Mehrara B, Morrow M, Barrio AV (2022) Risk factors and racial and ethnic disparities in patients with breast cancer-related lymphedema. JAMA Oncol 8:1195\u20131200. https:\/\/doi.org\/10.1001\/jamaoncol.2022.1628","journal-title":"JAMA Oncol"},{"key":"6947_CR33","doi-asserted-by":"publisher","first-page":"8624","DOI":"10.1245\/s10434-021-10173-0","volume":"28","author":"LK Bucci","year":"2021","unstructured":"Bucci LK, Brunelle CL, Bernstein MC, Shui AM, Gillespie TC, Roberts SA, Naoum GE, Taghian AG (2021) Subclinical lymphedema after treatment for breast cancer: risk of progression and considerations for early intervention. Ann Surg Oncol 28:8624\u20138633. https:\/\/doi.org\/10.1245\/s10434-021-10173-0","journal-title":"Ann Surg Oncol"},{"key":"6947_CR34","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-022-01242-8","author":"P Whitworth","year":"2022","unstructured":"Whitworth P, Vicini F, Valente SA, Brownson K, DuPree B, Kohli M, Lawson L, Shah C (2022) Reducing rates of chronic breast cancer-related lymphedema with screening and early intervention: an update of recent data. J Cancer Surviv. https:\/\/doi.org\/10.1007\/s11764-022-01242-8","journal-title":"J Cancer Surviv"},{"key":"6947_CR35","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1002\/cncr.31873","volume":"125","author":"LA Koelmeyer","year":"2019","unstructured":"Koelmeyer LA, Borotkanics RJ, Alcorso J, Prah P, Winch CJ, Nakhel K, Dean CM, Boyages J (2019) Early surveillance is associated with less incidence and severity of breast cancer-related lymphedema compared with a traditional referral model of care. Cancer 125:854\u2013862. https:\/\/doi.org\/10.1002\/cncr.31873","journal-title":"Cancer"},{"key":"6947_CR36","doi-asserted-by":"publisher","DOI":"10.1089\/lrb.2021.0084","author":"SH Ridner","year":"2022","unstructured":"Ridner SH, Dietrich MS, Boyages J, Koelmeyer L, Elder E, Hughes TM, French J, Ngui N, Hsu J, Abramson VG, Moore A, Shah C (2022) A comparison of bioimpedance spectroscopy or tape measure triggered compression intervention in chronic breast cancer lymphedema prevention. Lymphat Res Biol. https:\/\/doi.org\/10.1089\/lrb.2021.0084","journal-title":"Lymphat Res Biol"},{"key":"6947_CR37","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s10549-022-06667-4","volume":"195","author":"MB Aldrich","year":"2022","unstructured":"Aldrich MB, Rasmussen JC, DeSnyder SM, Woodward WA, Chan W, Sevick-Muraca EM, Mittendorf EA, Smith BD, Stauder MC, Strom EA, Perkins GH, Hoffman KE, Mitchell MP, Barcenas CH, Isales LE, Shaitelman SF (2022) Prediction of breast cancer-related lymphedema by dermal backflow detected with near-infrared fluorescence lymphatic imaging. Breast Cancer Res Treat 195:33\u201341. https:\/\/doi.org\/10.1007\/s10549-022-06667-4","journal-title":"Breast Cancer Res Treat"},{"key":"6947_CR38","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1089\/lrb.2014.0035","volume":"12","author":"A Soran","year":"2014","unstructured":"Soran A, Ozmen T, McGuire KP, Diego EJ, McAuliffe PF, Bonaventura M, Ahrendt GM, DeGore L, Johnson R (2014) The importance of detection of subclinical lymphedema for the prevention of breast cancer-related clinical lymphedema after axillary lymph node dissection; a prospective observational study. Lymphat Res Biol 12:289\u2013294. https:\/\/doi.org\/10.1089\/lrb.2014.0035","journal-title":"Lymphat Res Biol"},{"key":"6947_CR39","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3389\/fonc.2018.00197","volume":"8","author":"PW Whitworth","year":"2018","unstructured":"Whitworth PW, Shah C, Vicini F, Cooper A (2018) Preventing breast cancer-related lymphedema in high-risk patients: the impact of a structured surveillance protocol using bioimpedance spectroscopy. Front Oncol 8:197. https:\/\/doi.org\/10.3389\/fonc.2018.00197","journal-title":"Front Oncol"},{"key":"6947_CR40","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1111\/tbj.12939","volume":"24","author":"PW Whitworth","year":"2018","unstructured":"Whitworth PW, Cooper A (2018) Reducing chronic breast cancer-related lymphedema utilizing a program of prospective surveillance with bioimpedance spectroscopy. Breast J 24:62\u201365. https:\/\/doi.org\/10.1111\/tbj.12939","journal-title":"Breast J"},{"key":"6947_CR41","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1023\/a:1016591121762","volume":"75","author":"RC Box","year":"2002","unstructured":"Box RC, Reul-Hirche HM, Bullock-Saxton JE, Furnival CM (2002) Physiotherapy after breast cancer surgery: results of a randomised controlled study to minimise lymphoedema. Breast Cancer Res Treat 75:51\u201364. https:\/\/doi.org\/10.1023\/a:1016591121762","journal-title":"Breast Cancer Res Treat"},{"key":"6947_CR42","doi-asserted-by":"publisher","first-page":"2948","DOI":"10.1245\/s10434-018-6601-8","volume":"25","author":"LJ Kilgore","year":"2018","unstructured":"Kilgore LJ, Korentager SS, Hangge AN, Amin AL, Balanoff CR, Larson KE, Mitchell MP, Chen JG, Burgen E, Khan QJ, O\u2019Dea AP, Nye L, Sharma P, Wagner JL (2018) Reducing breast cancer-related lymphedema (BCRL) through prospective surveillance monitoring using bioimpedance spectroscopy (BIS) and patient directed self-interventions. Ann Surg Oncol 25:2948\u20132952. https:\/\/doi.org\/10.1245\/s10434-018-6601-8","journal-title":"Ann Surg Oncol"},{"key":"6947_CR43","doi-asserted-by":"publisher","first-page":"b5396","DOI":"10.1136\/bmj.b5396","volume":"340","author":"M Torres Lacomba","year":"2010","unstructured":"Torres Lacomba M, Yuste Sanchez MJ, Zapico Goni A, Prieto Merino D, Mayoral del Moral O, Cerezo Tellez E, Minayo Mogollon E (2010) Effectiveness of early physiotherapy to prevent lymphoedema after surgery for breast cancer: randomised, single blinded, clinical trial. BMJ 340:b5396. https:\/\/doi.org\/10.1136\/bmj.b5396","journal-title":"BMJ"},{"key":"6947_CR44","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.02567","author":"VS Paramanandam","year":"2022","unstructured":"Paramanandam VS, Dylke E, Clark GM, Daptardar AA, Kulkarni AM, Nair NS, Badwe RA, Kilbreath SL (2022) Prophylactic use of compression sleeves reduces the incidence of arm swelling in women at high risk of breast cancer-related lymphedema: a randomized controlled trial. J Clin Oncol. https:\/\/doi.org\/10.1200\/JCO.21.02567","journal-title":"J Clin Oncol"},{"key":"6947_CR45","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1097\/00006199-200311000-00004","volume":"52","author":"JM Armer","year":"2003","unstructured":"Armer JM, Radina ME, Porock D, Culbertson SD (2003) Predicting breast cancer-related lymphedema using self-reported symptoms. Nurs Res 52:370\u2013379. https:\/\/doi.org\/10.1097\/00006199-200311000-00004","journal-title":"Nurs Res"},{"key":"6947_CR46","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1200\/JCO.2008.17.9291","volume":"27","author":"SA Norman","year":"2009","unstructured":"Norman SA, Localio AR, Potashnik SL, Simoes Torpey HA, Kallan MJ, Weber AL, Miller LT, Demichele A, Solin LJ (2009) Lymphedema in breast cancer survivors: incidence, degree, time course, treatment, and symptoms. J Clin Oncol 27:390\u2013397. https:\/\/doi.org\/10.1200\/JCO.2008.17.9291","journal-title":"J Clin Oncol"},{"key":"6947_CR47","doi-asserted-by":"publisher","first-page":"1937","DOI":"10.1056\/NEJMcp1803290","volume":"379","author":"SG Rockson","year":"2018","unstructured":"Rockson SG (2018) Lymphedema after breast cancer treatment. N Engl J Med 379:1937\u20131944. https:\/\/doi.org\/10.1056\/NEJMcp1803290","journal-title":"N Engl J Med"},{"key":"6947_CR48","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.breast.2018.12.009","volume":"44","author":"A Michelotti","year":"2019","unstructured":"Michelotti A, Invernizzi M, Lopez G, Lorenzini D, Nesa F, De Sire A, Fusco N (2019) Tackling the diversity of breast cancer related lymphedema: perspectives on diagnosis, risk assessment, and clinical management. Breast 44:15\u201323. https:\/\/doi.org\/10.1016\/j.breast.2018.12.009","journal-title":"Breast"},{"key":"6947_CR49","unstructured":"National Lymphedema Network (2012) NLN Position Paper: Lymphedema Risk Reduction Practices. https:\/\/static1.squarespace.com\/static\/5b741fa71aef1d1e6500b325\/t\/621c4aa760809f553732d386\/1646021287719\/risk_reduction_summary+.pdf. Accessed 16 Jan 2023"},{"key":"6947_CR50","doi-asserted-by":"publisher","first-page":"2312","DOI":"10.1002\/cncr.27461","volume":"118","author":"SR Harris","year":"2012","unstructured":"Harris SR, Schmitz KH, Campbell KL, McNeely ML (2012) Clinical practice guidelines for breast cancer rehabilitation: syntheses of guideline recommendations and qualitative appraisals. Cancer 118:2312\u20132324. https:\/\/doi.org\/10.1002\/cncr.27461","journal-title":"Cancer"},{"key":"6947_CR51","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1007\/s13187-016-1026-1","volume":"32","author":"P Borman","year":"2017","unstructured":"Borman P, Yaman A, Yasrebi S, Ozdemir O (2017) The importance of awareness and education in patients with breast cancer-related lymphedema. J Cancer Educ 32:629\u2013633. https:\/\/doi.org\/10.1007\/s13187-016-1026-1","journal-title":"J Cancer Educ"},{"key":"6947_CR52","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.pec.2005.02.009","volume":"61","author":"SH Ridner","year":"2006","unstructured":"Ridner SH (2006) Pretreatment lymphedema education and identified educational resources in breast cancer patients. Patient Educ Couns 61:72\u201379. https:\/\/doi.org\/10.1016\/j.pec.2005.02.009","journal-title":"Patient Educ Couns"},{"key":"6947_CR53","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.13704","author":"P Martinez-Jaimez","year":"2022","unstructured":"Martinez-Jaimez P, Fuster Linares P, Piller N, Masia J, Yamamoto T, Lopez-Montoya L, Monforte-Royo C (2022) Multidisciplinary preventive intervention for breast cancer-related lymphedema: an international consensus. Eur J Cancer Care (Engl). https:\/\/doi.org\/10.1111\/ecc.13704","journal-title":"Eur J Cancer Care (Engl)"},{"key":"6947_CR54","doi-asserted-by":"publisher","first-page":"2191","DOI":"10.1002\/cncr.27476","volume":"118","author":"NL Stout","year":"2012","unstructured":"Stout NL, Binkley JM, Schmitz KH, Andrews K, Hayes SC, Campbell KL, McNeely ML, Soballe PW, Berger AM, Cheville AL, Fabian C, Gerber LH, Harris SR, Johansson K, Pusic AL, Prosnitz RG, Smith RA (2012) A prospective surveillance model for rehabilitation for women with breast cancer. Cancer 118:2191\u20132200. https:\/\/doi.org\/10.1002\/cncr.27476","journal-title":"Cancer"},{"key":"6947_CR55","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1200\/EDBK_280471","volume":"40","author":"SA McLaughlin","year":"2020","unstructured":"McLaughlin SA, Stout NL, Schaverien MV (2020) Avoiding the swell: advances in lymphedema prevention, detection, and management. Am Soc Clin Oncol Educ Book 40:1\u201310. https:\/\/doi.org\/10.1200\/EDBK_280471","journal-title":"Am Soc Clin Oncol Educ Book"},{"key":"6947_CR56","doi-asserted-by":"publisher","first-page":"152","DOI":"10.2522\/ptj.20100167","volume":"92","author":"NL Stout","year":"2012","unstructured":"Stout NL, Pfalzer LA, Springer B, Levy E, McGarvey CL, Danoff JV, Gerber LH, Soballe PW (2012) Breast cancer-related lymphedema: comparing direct costs of a prospective surveillance model and a traditional model of care. Phys Ther 92:152\u2013163. https:\/\/doi.org\/10.2522\/ptj.20100167","journal-title":"Phys Ther"},{"key":"6947_CR57","doi-asserted-by":"publisher","first-page":"153","DOI":"10.3390\/jpm5020153","volume":"5","author":"C Brunelle","year":"2015","unstructured":"Brunelle C, Skolny M, Ferguson C, Swaroop M, O\u2019Toole J, Taghian AG (2015) Establishing and sustaining a prospective screening program for breast cancer-related lymphedema at the massachusetts general hospital: lessons learned. J Pers Med 5:153\u2013164. https:\/\/doi.org\/10.3390\/jpm5020153","journal-title":"J Pers Med"},{"key":"6947_CR58","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1007\/s00520-020-05597-5","volume":"29","author":"L Koelmeyer","year":"2021","unstructured":"Koelmeyer L, Gaitatzis K, Ridner SH, Boyages J, Nelms J, Hughes TM, Elder E, French J, Ngui N, Hsu J, Stolldorf D (2021) Implementing a prospective surveillance and early intervention model of care for breast cancer-related lymphedema into clinical practice: application of the RE-AIM framework. Support Care Cancer 29:1081\u20131089. https:\/\/doi.org\/10.1007\/s00520-020-05597-5","journal-title":"Support Care Cancer"},{"key":"6947_CR59","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s10549-020-05953-3","volume":"185","author":"LA Koelmeyer","year":"2021","unstructured":"Koelmeyer LA, Moloney E, Boyages J, Sherman KA, Dean CM (2021) Prospective surveillance model in the home for breast cancer-related lymphoedema: a feasibility study. Breast Cancer Res Treat 185:401\u2013412. https:\/\/doi.org\/10.1007\/s10549-020-05953-3","journal-title":"Breast Cancer Res Treat"},{"key":"6947_CR60","doi-asserted-by":"publisher","first-page":"1890","DOI":"10.1245\/s10434-007-9412-x","volume":"14","author":"M Thompson","year":"2007","unstructured":"Thompson M, Korourian S, Henry-Tillman R, Adkins L, Mumford S, Westbrook KC, Klimberg VS (2007) Axillary reverse mapping (ARM): a new concept to identify and enhance lymphatic preservation. Ann Surg Oncol 14:1890\u20131895. https:\/\/doi.org\/10.1245\/s10434-007-9412-x","journal-title":"Ann Surg Oncol"},{"key":"6947_CR61","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1097\/SLA.0000000000001778","volume":"265","author":"E Tummel","year":"2017","unstructured":"Tummel E, Ochoa D, Korourian S, Betzold R, Adkins L, McCarthy M, Hung S, Kalkwarf K, Gallagher K, Lee JY, Klimberg VS (2017) Does axillary reverse mapping prevent lymphedema after lymphadenectomy? Ann Surg 265:987\u2013992. https:\/\/doi.org\/10.1097\/SLA.0000000000001778","journal-title":"Ann Surg"},{"key":"6947_CR62","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1002\/bjs.10041","volume":"103","author":"M Ahmed","year":"2016","unstructured":"Ahmed M, Rubio IT, Kovacs T, Klimberg VS, Douek M (2016) Systematic review of axillary reverse mapping in breast cancer. Br J Surg 103:170\u2013178. https:\/\/doi.org\/10.1002\/bjs.10041","journal-title":"Br J Surg"},{"key":"6947_CR63","doi-asserted-by":"publisher","first-page":"e0150285","DOI":"10.1371\/journal.pone.0150285","volume":"11","author":"C Han","year":"2016","unstructured":"Han C, Yang B, Zuo WS, Zheng G, Yang L, Zheng MZ (2016) The feasibility and oncological safety of axillary reverse mapping in patients with breast cancer: a systematic review and meta-analysis of prospective studies. PLoS ONE 11:e0150285. https:\/\/doi.org\/10.1371\/journal.pone.0150285","journal-title":"PLoS ONE"},{"key":"6947_CR64","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1245\/s10434-008-0270-y","volume":"16","author":"F Boccardo","year":"2009","unstructured":"Boccardo F, Casabona F, De Cian F, Friedman D, Villa G, Bogliolo S, Ferrero S, Murelli F, Campisi C (2009) Lymphedema microsurgical preventive healing approach: a new technique for primary prevention of arm lymphedema after mastectomy. Ann Surg Oncol 16:703\u2013708. https:\/\/doi.org\/10.1245\/s10434-008-0270-y","journal-title":"Ann Surg Oncol"},{"key":"6947_CR65","doi-asserted-by":"publisher","first-page":"2827","DOI":"10.1245\/s10434-017-5964-6","volume":"24","author":"SA McLaughlin","year":"2017","unstructured":"McLaughlin SA, DeSnyder SM, Klimberg S, Alatriste M, Boccardo F, Smith ML, Staley AC, Thiruchelvam PTR, Hutchison NA, Mendez J, MacNeill F, Vicini F, Rockson SG, Feldman SM (2017) Considerations for clinicians in the diagnosis, prevention, and treatment of breast cancer-related lymphedema, recommendations from an expert panel: part 2: preventive and therapeutic options. Ann Surg Oncol 24:2827\u20132835. https:\/\/doi.org\/10.1245\/s10434-017-5964-6","journal-title":"Ann Surg Oncol"},{"key":"6947_CR66","doi-asserted-by":"publisher","first-page":"2500","DOI":"10.1245\/s10434-011-1624-4","volume":"18","author":"FM Boccardo","year":"2011","unstructured":"Boccardo FM, Casabona F, Friedman D, Puglisi M, De Cian F, Ansaldi F, Campisi C (2011) Surgical prevention of arm lymphedema after breast cancer treatment. Ann Surg Oncol 18:2500\u20132505. https:\/\/doi.org\/10.1245\/s10434-011-1624-4","journal-title":"Ann Surg Oncol"},{"key":"6947_CR67","doi-asserted-by":"publisher","first-page":"3284","DOI":"10.1002\/cncr.34374","volume":"128","author":"CJ Hyland","year":"2022","unstructured":"Hyland CJ, Manrique OJ, Weiss A, Broyles JM (2022) Preventive strategies for breast cancer-related lymphedema: working toward optimal patient selection. Cancer 128:3284\u20133286. https:\/\/doi.org\/10.1002\/cncr.34374","journal-title":"Cancer"},{"key":"6947_CR68","doi-asserted-by":"publisher","first-page":"5742","DOI":"10.1245\/s10434-021-10494-0","volume":"28","author":"SM DeSnyder","year":"2021","unstructured":"DeSnyder SM, Yi M, Boccardo F, Feldman S, Klimberg VS, Smith M, Thiruchelvam PTR, McLaughlin S (2021) American Society of Breast Surgeons\u2019 practice patterns for patients at risk and affected by breast cancer-related lymphedema. Ann Surg Oncol 28:5742\u20135751. https:\/\/doi.org\/10.1245\/s10434-021-10494-0","journal-title":"Ann Surg Oncol"},{"key":"6947_CR69","doi-asserted-by":"publisher","first-page":"1713","DOI":"10.1016\/j.ejso.2022.04.023","volume":"48","author":"T Ozmen","year":"2022","unstructured":"Ozmen T, Layton C, Friedman-Eldar O, Melnikau S, Kesmodel S, Moller MG, Avisar E (2022) Evaluation of simplified lymphatic microsurgical preventing healing approach (SLYMPHA) for the prevention of breast cancer-related lymphedema after axillary lymph node dissection using bioimpedance spectroscopy. Eur J Surg Oncol 48:1713\u20131717. https:\/\/doi.org\/10.1016\/j.ejso.2022.04.023","journal-title":"Eur J Surg Oncol"},{"key":"6947_CR70","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1038\/s41572-019-0072-5","volume":"5","author":"SG Rockson","year":"2019","unstructured":"Rockson SG, Keeley V, Kilbreath S, Szuba A, Towers A (2019) Cancer-associated secondary lymphoedema. Nat Rev Dis Primers 5:22. https:\/\/doi.org\/10.1038\/s41572-019-0072-5","journal-title":"Nat Rev Dis Primers"},{"key":"6947_CR71","first-page":"3","volume":"53","author":"Executive Committee of the International Society of L","year":"2020","unstructured":"Executive Committee of the International Society of L (2020) The diagnosis and treatment of peripheral lymphedema: 2020 Consensus Document of the International Society of Lymphology. Lymphology 53:3\u201319","journal-title":"Lymphology"},{"key":"6947_CR72","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/j.pmrj.2012.05.003","volume":"4","author":"BB Lasinski","year":"2012","unstructured":"Lasinski BB, McKillip Thrift K, Squire D, Austin MK, Smith KM, Wanchai A, Green JM, Stewart BR, Cormier JN, Armer JM (2012) A systematic review of the evidence for complete decongestive therapy in the treatment of lymphedema from 2004 to 2011. PM R 4:580\u2013601. https:\/\/doi.org\/10.1016\/j.pmrj.2012.05.003","journal-title":"PM R"},{"key":"6947_CR73","volume-title":"Foldi\u2019s textbook of lymphology for physicians and lymphedema therapiests","author":"M Foldi","year":"2006","unstructured":"Foldi M (2006) Chapter 11. Complete decongestive therapy. In: Foldi MF, Strossenreuther E, Kubiks RS (eds) Foldi\u2019s textbook of lymphology for physicians and lymphedema therapiests. Elsevier, Munich"},{"key":"6947_CR74","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1093\/ptj\/pzaa087","volume":"100","author":"C Davies","year":"2020","unstructured":"Davies C, Levenhagen K, Ryans K, Perdomo M, Gilchrist L (2020) Interventions for breast cancer-related lymphedema: clinical practice guideline from the academy of oncologic physical therapy of APTA. Phys Ther 100:1163\u20131179. https:\/\/doi.org\/10.1093\/ptj\/pzaa087","journal-title":"Phys Ther"},{"key":"6947_CR75","doi-asserted-by":"publisher","first-page":"461","DOI":"10.2165\/00007256-200535060-00001","volume":"35","author":"K Lane","year":"2005","unstructured":"Lane K, Worsley D, McKenzie D (2005) Exercise and the lymphatic system: implications for breast-cancer survivors. Sports Med 35:461\u2013471. https:\/\/doi.org\/10.2165\/00007256-200535060-00001","journal-title":"Sports Med"},{"key":"6947_CR76","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.ejogrb.2009.11.016","volume":"149","author":"N Devoogdt","year":"2010","unstructured":"Devoogdt N, Van Kampen M, Geraerts I, Coremans T, Christiaens MR (2010) Different physical treatment modalities for lymphoedema developing after axillary lymph node dissection for breast cancer: a review. Eur J Obstet Gynecol Reprod Biol 149:3\u20139. https:\/\/doi.org\/10.1016\/j.ejogrb.2009.11.016","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"6947_CR77","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1186\/s12885-019-6192-1","volume":"19","author":"H Suami","year":"2019","unstructured":"Suami H, Heydon-White A, Mackie H, Czerniec S, Koelmeyer L, Boyages J (2019) A new indocyanine green fluorescence lymphography protocol for identification of the lymphatic drainage pathway for patients with breast cancer-related lymphoedema. BMC Cancer 19:985. https:\/\/doi.org\/10.1186\/s12885-019-6192-1","journal-title":"BMC Cancer"},{"key":"6947_CR78","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1089\/lrb.2020.0090","volume":"19","author":"LA Koelmeyer","year":"2021","unstructured":"Koelmeyer LA, Thompson BM, Mackie H, Blackwell R, Heydon-White A, Moloney E, Gaitatzis K, Boyages J, Suami H (2021) Personalizing conservative lymphedema management using indocyanine green-guided manual lymphatic drainage. Lymphat Res Biol 19:56\u201365. https:\/\/doi.org\/10.1089\/lrb.2020.0090","journal-title":"Lymphat Res Biol"},{"key":"6947_CR79","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-022-01262-4","author":"M Perdomo","year":"2022","unstructured":"Perdomo M, Davies C, Levenhagen K, Ryans K, Gilchrist L (2022) Patient education for breast cancer-related lymphedema: a systematic review. J Cancer Surviv. https:\/\/doi.org\/10.1007\/s11764-022-01262-4","journal-title":"J Cancer Surviv"},{"key":"6947_CR80","doi-asserted-by":"publisher","first-page":"3593","DOI":"10.1007\/s00520-020-05521-x","volume":"28","author":"T Hasenoehrl","year":"2020","unstructured":"Hasenoehrl T, Palma S, Ramazanova D, Kolbl H, Dorner TE, Keilani M, Crevenna R (2020) Resistance exercise and breast cancer-related lymphedema-a systematic review update and meta-analysis. Support Care Cancer 28:3593\u20133603. https:\/\/doi.org\/10.1007\/s00520-020-05521-x","journal-title":"Support Care Cancer"},{"key":"6947_CR81","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10549-016-3919-4","volume":"159","author":"S Rogan","year":"2016","unstructured":"Rogan S, Taeymans J, Luginbuehl H, Aebi M, Mahnig S, Gebruers N (2016) Therapy modalities to reduce lymphoedema in female breast cancer patients: a systematic review and meta-analysis. Breast Cancer Res Treat 159:1\u201314. https:\/\/doi.org\/10.1007\/s10549-016-3919-4","journal-title":"Breast Cancer Res Treat"},{"key":"6947_CR82","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s10549-006-9297-6","volume":"101","author":"S Vignes","year":"2007","unstructured":"Vignes S, Porcher R, Arrault M, Dupuy A (2007) Long-term management of breast cancer-related lymphedema after intensive decongestive physiotherapy. Breast Cancer Res Treat 101:285\u2013290. https:\/\/doi.org\/10.1007\/s10549-006-9297-6","journal-title":"Breast Cancer Res Treat"},{"key":"6947_CR83","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1002\/cncr.33183","volume":"127","author":"ED Paskett","year":"2021","unstructured":"Paskett ED, Le-Rademacher J, Oliveri JM, Liu H, Seisler DK, Sloan JA, Armer JM, Naughton MJ, Hock K, Schwartz M, Unzeitig G, Melnik M, Yee LD, Fleming GF, Taylor JR, Loprinzi C (2021) A randomized study to prevent lymphedema in women treated for breast cancer: CALGB 70305 (Alliance). Cancer 127:291\u2013299. https:\/\/doi.org\/10.1002\/cncr.33183","journal-title":"Cancer"},{"key":"6947_CR84","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003475.pub2","author":"J Ezzo","year":"2015","unstructured":"Ezzo J, Manheimer E, McNeely ML, Howell DM, Weiss R, Johansson KI, Bao T, Bily L, Tuppo CM, Williams AF, Karadibak D (2015) Manual lymphatic drainage for lymphedema following breast cancer treatment. Cochrane Database Syst Rev. https:\/\/doi.org\/10.1002\/14651858.CD003475.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"6947_CR85","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1007\/s11764-020-00928-1","volume":"15","author":"B Thompson","year":"2021","unstructured":"Thompson B, Gaitatzis K, Janse de Jonge X, Blackwell R, Koelmeyer LA (2021) Manual lymphatic drainage treatment for lymphedema: a systematic review of the literature. J Cancer Surviv 15:244\u2013258. https:\/\/doi.org\/10.1007\/s11764-020-00928-1","journal-title":"J Cancer Surviv"},{"key":"6947_CR86","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1038\/s41416-018-0306-4","volume":"119","author":"M Tambour","year":"2018","unstructured":"Tambour M, Holt M, Speyer A, Christensen R, Gram B (2018) Manual lymphatic drainage adds no further volume reduction to Complete Decongestive Therapy on breast cancer-related lymphoedema: a multicentre, randomised, single-blind trial. Br J Cancer 119:1215\u20131222. https:\/\/doi.org\/10.1038\/s41416-018-0306-4","journal-title":"Br J Cancer"},{"key":"6947_CR87","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1080\/028418600750013186","volume":"39","author":"L Andersen","year":"2000","unstructured":"Andersen L, Hojris I, Erlandsen M, Andersen J (2000) Treatment of breast-cancer-related lymphedema with or without manual lymphatic drainage\u2014a randomized study. Acta Oncol 39:399\u2013405. https:\/\/doi.org\/10.1080\/028418600750013186","journal-title":"Acta Oncol"},{"key":"6947_CR88","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1016\/j.jpainsymman.2015.06.017","volume":"50","author":"T Gradalski","year":"2015","unstructured":"Gradalski T, Ochalek K, Kurpiewska J (2015) Complex Decongestive Lymphatic Therapy with or without Vodder II manual lymph drainage in more severe chronic postmastectomy upper limb lymphedema: a randomized noninferiority prospective study. J Pain Symptom Manag 50:750\u2013757. https:\/\/doi.org\/10.1016\/j.jpainsymman.2015.06.017","journal-title":"J Pain Symptom Manag"},{"key":"6947_CR89","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/1477-7819-11-15","volume":"11","author":"TW Huang","year":"2013","unstructured":"Huang TW, Tseng SH, Lin CC, Bai CH, Chen CS, Hung CS, Wu CH, Tam KW (2013) Effects of manual lymphatic drainage on breast cancer-related lymphedema: a systematic review and meta-analysis of randomized controlled trials. World J Surg Oncol 11:15. https:\/\/doi.org\/10.1186\/1477-7819-11-15","journal-title":"World J Surg Oncol"},{"key":"6947_CR90","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2022.01.013","author":"Y Lin","year":"2022","unstructured":"Lin Y, Yang Y, Zhang X, Li W, Li H, Mu D (2022) Manual lymphatic drainage for breast cancer-related lymphedema: a systematic review and meta-analysis of randomized controlled trials. Clin Breast Cancer. https:\/\/doi.org\/10.1016\/j.clbc.2022.01.013","journal-title":"Clin Breast Cancer"},{"key":"6947_CR91","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzac137","author":"T De Vrieze","year":"2022","unstructured":"De Vrieze T, Gebruers N, Nevelsteen I, Thomis S, De Groef A, Tjalma WAA, Belgrado JP, Vandermeeren L, Monten C, Hanssens M, Asnong A, Dams L, Van der Gucht E, Heroes AK, Devoogdt N (2022) Does manual lymphatic drainage add value in reducing arm volume in patients with breast cancer-related lymphedema? Phys Ther. https:\/\/doi.org\/10.1093\/ptj\/pzac137","journal-title":"Phys Ther"},{"key":"6947_CR92","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3322\/caac.20001","volume":"59","author":"BD Lawenda","year":"2009","unstructured":"Lawenda BD, Mondry TE, Johnstone PA (2009) Lymphedema: a primer on the identification and management of a chronic condition in oncologic treatment. CA Cancer J Clin 59:8\u201324. https:\/\/doi.org\/10.3322\/caac.20001","journal-title":"CA Cancer J Clin"},{"key":"6947_CR93","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11050402","author":"M Pappalardo","year":"2021","unstructured":"Pappalardo M, Starnoni M, Franceschini G, Baccarani A, De Santis G (2021) Breast cancer-related lymphedema: recent updates on diagnosis, severity and available treatments. J Pers Med. https:\/\/doi.org\/10.3390\/jpm11050402","journal-title":"J Pers Med"},{"key":"6947_CR94","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2022.03.008","author":"ER Finkelstein","year":"2022","unstructured":"Finkelstein ER, Ha M, Hanwright P, Ngaage LM, Yoon JS, Liang F, Nam AJ, Rasko YM (2022) A review of American insurance coverage and criteria for the conservative management of lymphedema. J Vasc Surg Venous Lymphat Disord. https:\/\/doi.org\/10.1016\/j.jvsv.2022.03.008","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"6947_CR95","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1097\/COC.0000000000000355","volume":"41","author":"TD Smile","year":"2018","unstructured":"Smile TD, Tendulkar R, Schwarz G, Arthur D, Grobmyer S, Valente S, Vicini F, Shah C (2018) A review of treatment for breast cancer-related lymphedema: paradigms for clinical practice. Am J Clin Oncol 41:178\u2013190. https:\/\/doi.org\/10.1097\/COC.0000000000000355","journal-title":"Am J Clin Oncol"},{"key":"6947_CR96","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.soncn.2012.11.004","volume":"29","author":"BB Lasinski","year":"2013","unstructured":"Lasinski BB (2013) Complete decongestive therapy for treatment of lymphedema. Semin Oncol Nurs 29:20\u201327. https:\/\/doi.org\/10.1016\/j.soncn.2012.11.004","journal-title":"Semin Oncol Nurs"},{"key":"6947_CR97","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/j.ijrobp.2006.09.024","volume":"67","author":"R Koul","year":"2007","unstructured":"Koul R, Dufan T, Russell C, Guenther W, Nugent Z, Sun X, Cooke AL (2007) Efficacy of complete decongestive therapy and manual lymphatic drainage on treatment-related lymphedema in breast cancer. Int J Radiat Oncol Biol Phys 67:841\u2013846. https:\/\/doi.org\/10.1016\/j.ijrobp.2006.09.024","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"6947_CR98","doi-asserted-by":"publisher","first-page":"3758","DOI":"10.1200\/JCO.2012.45.7192","volume":"31","author":"IS Dayes","year":"2013","unstructured":"Dayes IS, Whelan TJ, Julian JA, Parpia S, Pritchard KI, D\u2019Souza DP, Kligman L, Reise D, LeBlanc L, McNeely ML, Manchul L, Wiernikowski J, Levine MN (2013) Randomized trial of decongestive lymphatic therapy for the treatment of lymphedema in women with breast cancer. J Clin Oncol 31:3758\u20133763. https:\/\/doi.org\/10.1200\/JCO.2012.45.7192","journal-title":"J Clin Oncol"},{"key":"6947_CR99","first-page":"8","volume":"4","author":"K Godette","year":"2006","unstructured":"Godette K, Mondry TE, Johnstone PA (2006) Can manual treatment of lymphedema promote metastasis? J Soc Integr Oncol 4:8\u201312","journal-title":"J Soc Integr Oncol"},{"key":"6947_CR100","doi-asserted-by":"publisher","first-page":"2260","DOI":"10.1002\/cncr.10976","volume":"95","author":"A Szuba","year":"2002","unstructured":"Szuba A, Achalu R, Rockson SG (2002) Decongestive lymphatic therapy for patients with breast carcinoma-associated lymphedema. A randomized, prospective study of a role for adjunctive intermittent pneumatic compression. Cancer 95:2260\u20132267. https:\/\/doi.org\/10.1002\/cncr.10976","journal-title":"Cancer"},{"key":"6947_CR101","first-page":"13","volume":"45","author":"JL Feldman","year":"2012","unstructured":"Feldman JL, Stout NL, Wanchai A, Stewart BR, Cormier JN, Armer JM (2012) Intermittent pneumatic compression therapy: a systematic review. Lymphology 45:13\u201325","journal-title":"Lymphology"},{"key":"6947_CR102","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2022.06.016","author":"SG Rockson","year":"2022","unstructured":"Rockson SG, Whitworth PW, Cooper A, Kania S, Karnofel H, Nguyen M, Shadduck K, Gingerich P, Armer J (2022) Safety and effectiveness of a novel nonpneumatic active compression device for treating breast cancer-related lymphedema: a multicenter randomized, crossover trial (NILE). J Vasc Surg Venous Lymphat Disord. https:\/\/doi.org\/10.1016\/j.jvsv.2022.06.016","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"6947_CR103","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1186\/s12885-017-3852-x","volume":"17","author":"GD Baxter","year":"2017","unstructured":"Baxter GD, Liu L, Petrich S, Gisselman AS, Chapple C, Anders JJ, Tumilty S (2017) Low level laser therapy (photobiomodulation therapy) for breast cancer-related lymphedema: a systematic review. BMC Cancer 17:833. https:\/\/doi.org\/10.1186\/s12885-017-3852-x","journal-title":"BMC Cancer"},{"key":"6947_CR104","first-page":"168","volume":"44","author":"HN Mayrovitz","year":"2011","unstructured":"Mayrovitz HN, Davey S (2011) Changes in tissue water and indentation resistance of lymphedematous limbs accompanying low level laser therapy (LLLT) of fibrotic skin. Lymphology 44:168\u2013177","journal-title":"Lymphology"},{"key":"6947_CR105","first-page":"74","volume":"31","author":"NB Piller","year":"1998","unstructured":"Piller NB, Thelander A (1998) Treatment of chronic postmastectomy lymphedema with low level laser therapy: a 2.5 year follow-up. Lymphology 31:74\u201386","journal-title":"Lymphology"},{"key":"6947_CR106","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1002\/cncr.11641","volume":"98","author":"CJ Carati","year":"2003","unstructured":"Carati CJ, Anderson SN, Gannon BJ, Piller NB (2003) Treatment of postmastectomy lymphedema with low-level laser therapy: a double blind, placebo-controlled trial. Cancer 98:1114\u20131122. https:\/\/doi.org\/10.1002\/cncr.11641","journal-title":"Cancer"},{"key":"6947_CR107","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1089\/pho.2008.2330","volume":"27","author":"RW Lau","year":"2009","unstructured":"Lau RW, Cheing GL (2009) Managing postmastectomy lymphedema with low-level laser therapy. Photomed Laser Surg 27:763\u2013769. https:\/\/doi.org\/10.1089\/pho.2008.2330","journal-title":"Photomed Laser Surg"},{"key":"6947_CR108","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.jss.2010.03.050","volume":"165","author":"MT Ahmed Omar","year":"2011","unstructured":"Ahmed Omar MT, Abd-El-Gayed Ebid A, El Morsy AM (2011) Treatment of post-mastectomy lymphedema with laser therapy: double blind placebo control randomized study. J Surg Res 165:82\u201390. https:\/\/doi.org\/10.1016\/j.jss.2010.03.050","journal-title":"J Surg Res"},{"key":"6947_CR109","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1188\/13.ONF.383-393","volume":"40","author":"SH Ridner","year":"2013","unstructured":"Ridner SH, Poage-Hooper E, Kanar C, Doersam JK, Bond SM, Dietrich MS (2013) A pilot randomized trial evaluating low-level laser therapy as an alternative treatment to manual lymphatic drainage for breast cancer-related lymphedema. Oncol Nurs Forum 40:383\u2013393. https:\/\/doi.org\/10.1188\/13.ONF.383-393","journal-title":"Oncol Nurs Forum"},{"key":"6947_CR110","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1186\/s12885-022-10021-8","volume":"22","author":"D Mahmood","year":"2022","unstructured":"Mahmood D, Ahmad A, Sharif F, Arslan SA (2022) Clinical application of low-level laser therapy (photo-biomodulation therapy) in the management of breast cancer-related lymphedema: a systematic review. BMC Cancer 22:937. https:\/\/doi.org\/10.1186\/s12885-022-10021-8","journal-title":"BMC Cancer"},{"key":"6947_CR111","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s11764-014-0411-1","volume":"9","author":"B Smoot","year":"2015","unstructured":"Smoot B, Chiavola-Larson L, Lee J, Manibusan H, Allen DD (2015) Effect of low-level laser therapy on pain and swelling in women with breast cancer-related lymphedema: a systematic review and meta-analysis. J Cancer Surviv 9:287\u2013304. https:\/\/doi.org\/10.1007\/s11764-014-0411-1","journal-title":"J Cancer Surviv"},{"key":"6947_CR112","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1007\/s10103-012-1240-y","volume":"29","author":"EL Mt","year":"2014","unstructured":"Mt EL, Jg EL, de Andrade MF, Bergmann A (2014) Low-level laser therapy in secondary lymphedema after breast cancer: systematic review. Lasers Med Sci 29:1289\u20131295. https:\/\/doi.org\/10.1007\/s10103-012-1240-y","journal-title":"Lasers Med Sci"},{"key":"6947_CR113","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1055\/s-0038-1636510","volume":"32","author":"EI Chang","year":"2018","unstructured":"Chang EI, Skoracki RJ, Chang DW (2018) Lymphovenous anastomosis bypass surgery. Semin Plast Surg 32:22\u201327. https:\/\/doi.org\/10.1055\/s-0038-1636510","journal-title":"Semin Plast Surg"},{"key":"6947_CR114","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1097\/PRS.0b013e3182a4d626","volume":"132","author":"DW Chang","year":"2013","unstructured":"Chang DW, Suami H, Skoracki R (2013) A prospective analysis of 100 consecutive lymphovenous bypass cases for treatment of extremity lymphedema. Plast Reconstr Surg 132:1305\u20131314. https:\/\/doi.org\/10.1097\/PRS.0b013e3182a4d626","journal-title":"Plast Reconstr Surg"},{"key":"6947_CR115","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1097\/PRS.0000000000005870","volume":"144","author":"FK AlJindan","year":"2019","unstructured":"AlJindan FK, Lin CY, Cheng MH (2019) Comparison of outcomes between side-to-end and end-to-end lymphovenous anastomoses for early-grade extremity lymphedema. Plast Reconstr Surg 144:486\u2013496. https:\/\/doi.org\/10.1097\/PRS.0000000000005870","journal-title":"Plast Reconstr Surg"},{"key":"6947_CR116","unstructured":"Suami H, Chang DW (2012) New developments in microsurgery. In: Moffat C (ed) Lymphedema framework: best practice for the management of Lymphoedema. Surgical intervention. A position document on surgery for Lymphedema, 2 edn. The International Lymphoedema Framework and World Alliance for Wound and Lymphedema Care, Saint \u00c9tienne, pp 34\u201335"},{"key":"6947_CR117","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1016\/j.jamcollsurg.2021.03.002","volume":"232","author":"MV Schaverien","year":"2021","unstructured":"Schaverien MV, Asaad M, Selber JC, Liu J, Chen DN, Hall MS, Butler CE (2021) Outcomes of vascularized lymph node transplantation for treatment of lymphedema. J Am Coll Surg 232:982\u2013994. https:\/\/doi.org\/10.1016\/j.jamcollsurg.2021.03.002","journal-title":"J Am Coll Surg"},{"key":"6947_CR118","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1245\/s10434-014-3518-8","volume":"21","author":"JW Granzow","year":"2014","unstructured":"Granzow JW, Soderberg JM, Kaji AH, Dauphine C (2014) Review of current surgical treatments for lymphedema. Ann Surg Oncol 21:1195\u20131201. https:\/\/doi.org\/10.1245\/s10434-014-3518-8","journal-title":"Ann Surg Oncol"},{"key":"6947_CR119","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.1016\/j.bjps.2016.06.022","volume":"69","author":"CN Ozturk","year":"2016","unstructured":"Ozturk CN, Ozturk C, Glasgow M, Platek M, Ashary Z, Kuhn J, Aronoff N, Lohman R, Djohan R, Gurunluoglu R (2016) Free vascularized lymph node transfer for treatment of lymphedema: a systematic evidence based review. J Plast Reconstr Aesthet Surg 69:1234\u20131247. https:\/\/doi.org\/10.1016\/j.bjps.2016.06.022","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"6947_CR120","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1016\/j.jvsv.2021.08.023","volume":"10","author":"H Winters","year":"2022","unstructured":"Winters H, Tielemans HJP, Paulus V, Hummelink S, Slater NJ, Ulrich DJO (2022) A systematic review and meta-analysis of vascularized lymph node transfer for breast cancer-related lymphedema. J Vasc Surg Venous Lymphat Disord 10:786-797e781. https:\/\/doi.org\/10.1016\/j.jvsv.2021.08.023","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"6947_CR121","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1089\/lrb.2019.0048","volume":"18","author":"QD Ngo","year":"2020","unstructured":"Ngo QD, Munot S, Mackie H, Czerniec S, Koelmeyer LA, Lam T, Heydon-White A, Suami H, Boyages J (2020) Vascularized lymph node transfer for patients with breast cancer-related lymphedema can potentially reduce the burden of ongoing conservative management. Lymphat Res Biol 18:357\u2013364. https:\/\/doi.org\/10.1089\/lrb.2019.0048","journal-title":"Lymphat Res Biol"},{"key":"6947_CR122","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1186\/s40064-016-2300-8","volume":"5","author":"J Boyages","year":"2016","unstructured":"Boyages J, Kalfa S, Xu Y, Koelmeyer L, Mackie H, Viveros H, Taksa L, Gollan P (2016) Worse and worse off: the impact of lymphedema on work and career after breast cancer. Springerplus 5:657. https:\/\/doi.org\/10.1186\/s40064-016-2300-8","journal-title":"Springerplus"},{"key":"6947_CR123","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1002\/pon.4239","volume":"26","author":"J Boyages","year":"2017","unstructured":"Boyages J, Xu Y, Kalfa S, Koelmeyer L, Parkinson B, Mackie H, Viveros H, Gollan P, Taksa L (2017) Financial cost of lymphedema borne by women with breast cancer. Psychooncology 26:849\u2013855. https:\/\/doi.org\/10.1002\/pon.4239","journal-title":"Psychooncology"},{"key":"6947_CR124","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1016\/j.ejvs.2012.11.026","volume":"45","author":"S Vignes","year":"2013","unstructured":"Vignes S, Blanchard M, Yannoutsos A, Arrault M (2013) Complications of autologous lymph-node transplantation for limb lymphoedema. Eur J Vasc Endovasc Surg 45:516\u2013520. https:\/\/doi.org\/10.1016\/j.ejvs.2012.11.026","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"6947_CR125","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1177\/145749690309200409","volume":"92","author":"H Brorson","year":"2003","unstructured":"Brorson H (2003) Liposuction in arm lymphedema treatment. Scand J Surg 92:287\u2013295. https:\/\/doi.org\/10.1177\/145749690309200409","journal-title":"Scand J Surg"},{"key":"6947_CR126","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1055\/s-0038-1635116","volume":"32","author":"MV Schaverien","year":"2018","unstructured":"Schaverien MV, Munnoch DA, Brorson H (2018) Liposuction treatment of lymphedema. Semin Plast Surg 32:42\u201347. https:\/\/doi.org\/10.1055\/s-0038-1635116","journal-title":"Semin Plast Surg"},{"issue":"Suppl 3","key":"6947_CR127","doi-asserted-by":"publisher","first-page":"S1263","DOI":"10.1245\/s10434-015-4700-3","volume":"22","author":"J Boyages","year":"2015","unstructured":"Boyages J, Kastanias K, Koelmeyer LA, Winch CJ, Lam TC, Sherman KA, Munnoch DA, Brorson H, Ngo QD, Heydon-White A, Magnussen JS, Mackie H (2015) Liposuction for advanced lymphedema: a multidisciplinary approach for complete reduction of arm and leg swelling. Ann Surg Oncol 22(Suppl 3):S1263-1270. https:\/\/doi.org\/10.1245\/s10434-015-4700-3","journal-title":"Ann Surg Oncol"},{"key":"6947_CR128","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1080\/028418600750013195","volume":"39","author":"H Brorson","year":"2000","unstructured":"Brorson H (2000) Liposuction gives complete reduction of chronic large arm lymphedema after breast cancer. Acta Oncol 39:407\u2013420. https:\/\/doi.org\/10.1080\/028418600750013195","journal-title":"Acta Oncol"},{"key":"6947_CR129","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/j.bjps.2012.01.021","volume":"65","author":"MV Schaverien","year":"2012","unstructured":"Schaverien MV, Munro KJ, Baker PA, Munnoch DA (2012) Liposuction for chronic lymphoedema of the upper limb: 5 years of experience. J Plast Reconstr Aesthet Surg 65:935\u2013942. https:\/\/doi.org\/10.1016\/j.bjps.2012.01.021","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"6947_CR130","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1002\/bjs.6658","volume":"96","author":"RJ Damstra","year":"2009","unstructured":"Damstra RJ, Voesten HG, Klinkert P, Brorson H (2009) Circumferential suction-assisted lipectomy for lymphoedema after surgery for breast cancer. Br J Surg 96:859\u2013864. https:\/\/doi.org\/10.1002\/bjs.6658","journal-title":"Br J Surg"},{"key":"6947_CR131","first-page":"85","volume":"49","author":"D Lee","year":"2016","unstructured":"Lee D, Piller N, Hoffner M, Manjer J, Brorson H (2016) Liposuction of postmastectomy arm lymphedema decreases the incidence of erysipelas. Lymphology 49:85\u201392","journal-title":"Lymphology"},{"key":"6947_CR132","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1089\/lrb.2016.0035","volume":"15","author":"M Hoffner","year":"2017","unstructured":"Hoffner M, Bagheri S, Hansson E, Manjer J, Troeng T, Brorson H (2017) SF-36 shows increased quality of life following complete reduction of postmastectomy lymphedema with liposuction. Lymphat Res Biol 15:87\u201398. https:\/\/doi.org\/10.1089\/lrb.2016.0035","journal-title":"Lymphat Res Biol"},{"key":"6947_CR133","first-page":"118","volume":"43","author":"JM Armer","year":"2010","unstructured":"Armer JM, Stewart BR (2010) Post-breast cancer lymphedema: incidence increases from 12 to 30 to 60 months. Lymphology 43:118\u2013127","journal-title":"Lymphology"},{"key":"6947_CR134","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1002\/jso.25513","volume":"120","author":"GS Schwarz","year":"2019","unstructured":"Schwarz GS, Grobmyer SR, Djohan RS, Cakmakoglu C, Bernard SL, Radford D, Al-Hilli Z, Knackstedt R, Djohan M, Valente SA (2019) Axillary reverse mapping and lymphaticovenous bypass: lymphedema prevention through enhanced lymphatic visualization and restoration of flow. J Surg Oncol 120:160\u2013167. https:\/\/doi.org\/10.1002\/jso.25513","journal-title":"J Surg Oncol"},{"key":"6947_CR135","doi-asserted-by":"publisher","first-page":"4695","DOI":"10.1245\/s10434-020-08890-z","volume":"27","author":"K Shaffer","year":"2020","unstructured":"Shaffer K, Cakmakoglu C, Schwarz GS, ElSherif A, Al-Hilli Z, Djohan R, Radford DM, Grobmyer S, Bernard S, Moreira A, Fanning A, Tu C, Valente SA (2020) Lymphedema prevention surgery: improved operating efficiency over time. Ann Surg Oncol 27:4695\u20134701. https:\/\/doi.org\/10.1245\/s10434-020-08890-z","journal-title":"Ann Surg Oncol"},{"key":"6947_CR136","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.123775","author":"SG Rockson","year":"2018","unstructured":"Rockson SG, Tian W, Jiang X, Kuznetsova T, Haddad F, Zampell J, Mehrara B, Sampson JP, Roche L, Kim J, Nicolls MR (2018) Pilot studies demonstrate the potential benefits of antiinflammatory therapy in human lymphedema. JCI Insight. https:\/\/doi.org\/10.1172\/jci.insight.123775","journal-title":"JCI Insight"},{"key":"6947_CR137","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1002\/cpdd.1040","volume":"11","author":"MC Chen","year":"2022","unstructured":"Chen MC, Korth CC, Harnett MD, Elenko E, Lickliter JD (2022) A randomized phase 1 evaluation of deupirfenidone, a novel deuterium-containing drug candidate for interstitial lung disease and other inflammatory and fibrotic diseases. Clin Pharmacol Drug Dev 11:220\u2013234. https:\/\/doi.org\/10.1002\/cpdd.1040","journal-title":"Clin Pharmacol Drug Dev"},{"key":"6947_CR138","doi-asserted-by":"publisher","first-page":"1612","DOI":"10.1016\/j.bjps.2020.05.009","volume":"73","author":"P Hartiala","year":"2020","unstructured":"Hartiala P, Suominen S, Suominen E, Kaartinen I, Kiiski J, Viitanen T, Alitalo K, Saarikko AM (2020) Phase 1 Lymfactin(\u00ae) study: short-term safety of combined adenoviral VEGF-C and lymph node transfer treatment for upper extremity lymphedema. J Plast Reconstr Aesthet Surg 73:1612\u20131621. https:\/\/doi.org\/10.1016\/j.bjps.2020.05.009","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"6947_CR139","doi-asserted-by":"publisher","first-page":"OT1-06-01-OT01-","DOI":"10.1158\/1538-7445.Sabcs19-ot1-06-01","volume":"80","author":"P Hartiala","year":"2020","unstructured":"Hartiala P, Lahdenper\u00e4 O, Vuolanto A, Saarikko A (2020) Abstract OT1-06-01: Lymfactin, an investigational adenoviral gene therapy expressing VEGF-C, is currently studied in a double-blind, randomized, placebo-controlled, multicenter, phase 2 clinical study in patients suffering from breast cancer associated secondary lymphedema (BCAL). Cancer Res 80:OT1-06-01-OT01-06\u201301. https:\/\/doi.org\/10.1158\/1538-7445.Sabcs19-ot1-06-01","journal-title":"Cancer Res"},{"key":"6947_CR140","unstructured":"Herantis Pharma Plc (2021) Herantis announces inconclusive results from phase II study with Lymfactin in breast cancer related lymphedema. https:\/\/herantis.com\/press-releases\/herantis-announces-inconclusive-results-from-phase-ii-study-with-lymfactin-in-breast-cancer-related-lymphedema\/. Accessed 16 Jan 2023"},{"key":"6947_CR141","doi-asserted-by":"publisher","DOI":"10.3390\/biology10090934","author":"BJ Mehrara","year":"2021","unstructured":"Mehrara BJ, Park HJ, Kataru RP, Bromberg J, Coriddi M, Baik JE, Shin J, Li C, Cavalli MR, Encarnacion EM, Lee M, Van Zee KJ, Riedel E, Dayan JH (2021) Pilot study of anti-Th2 immunotherapy for the treatment of breast cancer-related upper extremity lymphedema. Biology (Basel). https:\/\/doi.org\/10.3390\/biology10090934","journal-title":"Biology (Basel)"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-023-06947-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10549-023-06947-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-023-06947-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T15:01:52Z","timestamp":1685199712000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10549-023-06947-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,27]]},"references-count":141,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["6947"],"URL":"https:\/\/doi.org\/10.1007\/s10549-023-06947-7","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,27]]},"assertion":[{"value":"30 January 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 April 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 April 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Financial Interests: P.M.C.D. is a paid consultant for PureTech Health and Tactile Medical and has received clinical and imaging grants from LymphaTouch, Inc. A.M. is a paid clinical advisor to AIROS Medical, Inc. and a paid consultant for PureTech Health. A.F. is a full-time employee of PureTech Health. L.K. has received research support from PureTech Health.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}