{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T22:52:23Z","timestamp":1789426343495,"version":"build-2803163510"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["21-75-30015"],"award-info":[{"award-number":["21-75-30015"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1007\/s10549-023-07135-3","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T08:02:19Z","timestamp":1697616139000},"page":"307-315","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Ethnicity-specific BRCA1, BRCA2, PALB2, and ATM pathogenic alleles in breast and ovarian cancer patients from the North Caucasus"],"prefix":"10.1007","volume":"203","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6304-1609","authenticated-orcid":false,"given":"Anna P.","family":"Sokolenko","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvina Kh.","family":"Bakaeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6504-8636","authenticated-orcid":false,"given":"Aigul R.","family":"Venina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2396-6540","authenticated-orcid":false,"given":"Ekaterina Sh.","family":"Kuligina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6549-8378","authenticated-orcid":false,"given":"Alexandr A.","family":"Romanko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2149-7728","authenticated-orcid":false,"given":"Svetlana N.","family":"Aleksakhina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yana V.","family":"Belysheva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2658-3860","authenticated-orcid":false,"given":"Evgeniya V.","family":"Belogubova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilya A.","family":"Stepanov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga A.","family":"Zaitseva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga S.","family":"Yatsuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3830-8364","authenticated-orcid":false,"given":"Alexandr V.","family":"Togo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaur M.","family":"Khamgokov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azinat O.","family":"Kadyrova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert Sh.","family":"Pirmagomedov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina B.","family":"Bolieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandr A.","family":"Epkhiev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aslan K.","family":"Tsutsaev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madina D.","family":"Chakhieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalimat M.","family":"Khabrieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idris M.","family":"Khabriev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirza A.","family":"Murachuev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bella N.","family":"Buttaeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliya S.","family":"Baboshkina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima I.","family":"Bayramkulova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Islam R.","family":"Katchiev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina Kh.","family":"Alieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grigory A.","family":"Raskin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey V.","family":"Orlov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zarema K.","family":"Khachmamuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine R.","family":"Levonyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariya M.","family":"Gichko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitriy V.","family":"Kirtbaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey M.","family":"Degtyariov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa V.","family":"Sultanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hedi S.","family":"Musayeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey M.","family":"Belyaev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4529-7891","authenticated-orcid":false,"given":"Evgeny N.","family":"Imyanitov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,18]]},"reference":[{"issue":"5182","key":"7135_CR1","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1126\/science.7545954","volume":"266","author":"Y Miki","year":"1994","unstructured":"Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Liu Q, Cochran C, Bennett LM, Ding W et al (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266(5182):66\u201371. https:\/\/doi.org\/10.1126\/science.7545954","journal-title":"Science"},{"issue":"6559","key":"7135_CR2","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1038\/378789a0","volume":"378","author":"R Wooster","year":"1995","unstructured":"Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, Gregory S, Gumbs C, Micklem G (1995) Identification of the breast cancer susceptibility gene BRCA2. Nature 378(6559):789\u2013792. https:\/\/doi.org\/10.1038\/378789a0","journal-title":"Nature"},{"issue":"3","key":"7135_CR3","first-page":"547","volume":"59","author":"TR Rebbeck","year":"1996","unstructured":"Rebbeck TR, Couch FJ, Kant J, Calzone K, DeShano M, Peng Y, Chen K, Garber JE, Weber BL (1996) Genetic heterogeneity in hereditary breast cancer: role of BRCA1 and BRCA2. Am J Hum Genet 59(3):547\u2013553","journal-title":"Am J Hum Genet"},{"issue":"5","key":"7135_CR4","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1038\/ng.569","volume":"42","author":"A Meindl","year":"2010","unstructured":"Meindl A, Hellebrand H, Wiek C, Erven V, Wappenschmidt B, Niederacher D, Freund M, Lichtner P, Hartmann L, Schaal H, Ramser J, Honisch E, Kubisch C, Wichmann HE, Kast K, Deissler H, Engel C, M\u00fcller-Myhsok B, Neveling K, Kiechle M, Mathew CG, Schindler D, Schmutzler RK, Hanenberg H (2010) Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat Genet 42(5):410\u2013414. https:\/\/doi.org\/10.1038\/ng.569","journal-title":"Nat Genet"},{"issue":"26","key":"7135_CR5","doi-asserted-by":"publisher","first-page":"2901","DOI":"10.1200\/JCO.2015.61.2408","volume":"33","author":"H Song","year":"2015","unstructured":"Song H, Dicks E, Ramus SJ, Tyrer JP, Intermaggio MP, Hayward J, Edlund CK, Conti D, Harrington P, Fraser L, Philpott S et al (2015) Contribution of germline mutations in the RAD51B, RAD51C, and RAD51D genes to ovarian cancer in the population. J Clin Oncol 33(26):2901\u20132907. https:\/\/doi.org\/10.1200\/JCO.2015.61.2408","journal-title":"J Clin Oncol"},{"issue":"12","key":"7135_CR6","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1038\/s41431-017-0021-2","volume":"25","author":"L Golmard","year":"2017","unstructured":"Golmard L, Cast\u00e9ra L, Krieger S, Moncoutier V, Abidallah K, Tenreiro H, Laug\u00e9 A, Tarabeux J, Millot GA, Nicolas A, La\u00e9 M, Abadie C, Berthet P, Polycarpe F, Fr\u00e9bourg T, Elan C, de Pauw A, Gauthier-Villars M, Buecher B, Stern MH, Stoppa-Lyonnet D, Vaur D, Houdayer C (2017) Contribution of germline deleterious variants in the RAD51 paralogs to breast and ovarian cancers. Eur J Hum Genet 25(12):1345\u20131353. https:\/\/doi.org\/10.1038\/s41431-017-0021-2","journal-title":"Eur J Hum Genet"},{"issue":"1","key":"7135_CR7","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/s13048-020-00654-3","volume":"13","author":"M Suszynska","year":"2020","unstructured":"Suszynska M, Ratajska M, Kozlowski P (2020) BRIP1, RAD51C, and RAD51D mutations are associated with high susceptibility to ovarian cancer: mutation prevalence and precise risk estimates based on a pooled analysis of ~30,000 cases. J Ovarian Res 13(1):50. https:\/\/doi.org\/10.1186\/s13048-020-00654-3","journal-title":"J Ovarian Res"},{"issue":"6","key":"7135_CR8","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1056\/NEJMoa1400382","volume":"371","author":"AC Antoniou","year":"2014","unstructured":"Antoniou AC, Casadei S, Heikkinen T, Barrowdale D, Pylk\u00e4s K, Roberts J, Lee A, Subramanian D, De Leeneer K, Fostira F et al (2014) Breast-cancer risk in families with mutations in PALB2. N Engl J Med 371(6):497\u2013506. https:\/\/doi.org\/10.1056\/NEJMoa1400382","journal-title":"N Engl J Med"},{"issue":"19","key":"7135_CR9","doi-asserted-by":"publisher","first-page":"11790","DOI":"10.3390\/ijms231911790","volume":"23","author":"A Abe","year":"2022","unstructured":"Abe A, Imoto I, Ueki A, Nomura H, Kanao H (2022) Moderate-risk genes for hereditary ovarian cancers involved in the homologous recombination repair pathway. Int J Mol Sci 23(19):11790. https:\/\/doi.org\/10.3390\/ijms231911790","journal-title":"Int J Mol Sci"},{"issue":"2","key":"7135_CR10","doi-asserted-by":"publisher","first-page":"40","DOI":"10.5306\/wjco.v14.i2.40","volume":"14","author":"EN Imyanitov","year":"2023","unstructured":"Imyanitov EN, Kuligina ES, Sokolenko AP, Suspitsin EN, Yanus GA, Iyevleva AG, Ivantsov AO, Aleksakhina SN (2023) Hereditary cancer syndromes. World J Clin Oncol 14(2):40\u201368. https:\/\/doi.org\/10.5306\/wjco.v14.i2.40","journal-title":"World J Clin Oncol"},{"key":"7135_CR11","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672320000075","volume":"102","author":"T Nguyen-Dumont","year":"2020","unstructured":"Nguyen-Dumont T, Karpinski P, Sasiadek MM, Akopyan H, Steen JA, Theys D, Hammet F, Tsimiklis H, Park DJ, Pope BJ, Slezak R, Stembalska A, Pesz K, Kitsera N, Siekierzynska A, Southey MC, Myszka A (2020) Genetic testing in Poland and Ukraine: should comprehensive germline testing of BRCA1 and BRCA2 be recommended for women with breast and ovarian cancer? Genet Res (Camb) 102:e6. https:\/\/doi.org\/10.1017\/S0016672320000075","journal-title":"Genet Res (Camb)"},{"issue":"1","key":"7135_CR12","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1007\/s10549-020-05827-8","volume":"184","author":"AP Sokolenko","year":"2020","unstructured":"Sokolenko AP, Sokolova TN, Ni VI, Preobrazhenskaya EV, Iyevleva AG, Aleksakhina SN, Romanko AA, Bessonov AA, Gorodnova TV, Anisimova EI, Savonevich EL, Bizin IV, Stepanov IA, Krivorotko PV, Berlev IV, Belyaev AM, Togo AV, Imyanitov EN (2020) Frequency and spectrum of founder and non-founder BRCA1 and BRCA2 mutations in a large series of Russian breast cancer and ovarian cancer patients. Breast Cancer Res Treat 184(1):229\u2013235. https:\/\/doi.org\/10.1007\/s10549-020-05827-8","journal-title":"Breast Cancer Res Treat"},{"issue":"1","key":"7135_CR13","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s10689-022-00296-y","volume":"22","author":"GA Yanus","year":"2023","unstructured":"Yanus GA, Savonevich EL, Sokolenko AP, Romanko AA, Ni VI, Bakaeva EK, Gorustovich OA, Bizin IV, Imyanitov EN (2023) Founder vs. non-founder BRCA1\/2 pathogenic alleles: the analysis of Belarusian breast and ovarian cancer patients and review of other studies on ethnically homogenous populations. Fam Cancer 22(1):19\u201330. https:\/\/doi.org\/10.1007\/s10689-022-00296-y","journal-title":"Fam Cancer"},{"issue":"18","key":"7135_CR14","doi-asserted-by":"publisher","first-page":"2788","DOI":"10.1016\/j.ejca.2004.09.008","volume":"40","author":"T Rafnar","year":"2004","unstructured":"Rafnar T, Benediktsdottir KR, Eldon BJ, Gestsson T, Saemundsson H, Olafsson K, Salvarsdottir A, Steingrimsson E, Thorlacius S (2004) BRCA2, but not BRCA1, mutations account for familial ovarian cancer in Iceland: a population-based study. Eur J Cancer 40(18):2788\u20132793. https:\/\/doi.org\/10.1016\/j.ejca.2004.09.008","journal-title":"Eur J Cancer"},{"issue":"13","key":"7135_CR15","doi-asserted-by":"publisher","first-page":"2309","DOI":"10.1093\/hmg\/6.13.2309","volume":"6","author":"P Vehmanen","year":"1997","unstructured":"Vehmanen P, Friedman LS, Eerola H, McClure M, Ward B, Sarantaus L, Kainu T, Syrj\u00e4koski K, Pyrh\u00f6nen S, Kallioniemi OP, Muhonen T, Luce M, Frank TS, Nevanlinna H (1997) Low proportion of BRCA1 and BRCA2 mutations in Finnish breast cancer families: evidence for additional susceptibility genes. Hum Mol Genet 6(13):2309\u20132315. https:\/\/doi.org\/10.1093\/hmg\/6.13.2309","journal-title":"Hum Mol Genet"},{"key":"7135_CR16","unstructured":"2021 Russian Census (2021) https:\/\/rosstat.gov.ru\/storage\/mediabank\/Tom5_tab1_VPN-2020.xlsx. Accessed 16 June 2023"},{"key":"7135_CR17","volume-title":"The North Caucasus: Minorities at a Crossroads","author":"H Krag","year":"1994","unstructured":"Krag H, Funch L (1994) The North Caucasus: Minorities at a Crossroads. Minority Rights Group, London"},{"issue":"10","key":"7135_CR18","doi-asserted-by":"publisher","first-page":"2905","DOI":"10.1093\/molbev\/msr126","volume":"28","author":"O Balanovsky","year":"2011","unstructured":"Balanovsky O, Dibirova K, Dybo A, Mudrak O, Frolova S, Pocheshkhova E, Haber M, Platt D, Schurr T, Haak W, Kuznetsova M, Radzhabov M, Balaganskaya O, Romanov A, Zakharova T, Soria Hernanz DF, Zalloua P, Koshel S, Ruhlen M, Renfrew C, Wells RS, Tyler-Smith C, Balanovska E, Genographic Consortium (2011) Parallel evolution of genes and languages in the Caucasus region. Mol Biol Evol 28(10):2905\u20132920. https:\/\/doi.org\/10.1093\/molbev\/msr126","journal-title":"Mol Biol Evol"},{"issue":"3","key":"7135_CR19","doi-asserted-by":"publisher","first-page":"3167","DOI":"10.1002\/cam4.5159","volume":"12","author":"AP Sokolenko","year":"2023","unstructured":"Sokolenko AP, Sultanova LV, Stepanov IA, Romanko AA, Venina AR, Sokolova TN, Musayeva HS, Tovgereeva MY, Magomedova MK, Akhmatkhanov KU, Vagapova EI, Suleymanov EA, Vasilyeva EV, Bakaeva EK, Bizin IV, Aleksakhina SN, Imyanitov EN (2023) Strong founder effect for BRCA1 c.3629_3630delAG pathogenic variant in Chechen patients with breast or ovarian cancer. Cancer Med 12(3):3167\u20133171. https:\/\/doi.org\/10.1002\/cam4.5159","journal-title":"Cancer Med"},{"issue":"7","key":"7135_CR20","doi-asserted-by":"publisher","first-page":"e0201086","DOI":"10.1371\/journal.pone.0201086","volume":"13","author":"A Kowalik","year":"2018","unstructured":"Kowalik A, Sio\u0142ek M, Kopczy\u0144ski J, Krawiec K, Kalisz J, Zi\u0119ba S, Kozak-Klonowska B, Wypi\u00f3rkiewicz E, Furma\u0144czyk J, Nowak-Ozimek E, Ch\u0142opek M, Macek P, Smok-Kalwat J, G\u00f3\u017ad\u017a S (2018) BRCA1 founder mutations and beyond in the Polish population: a single-institution BRCA1\/2 next-generation sequencing study. PloS one 13(7):e0201086. https:\/\/doi.org\/10.1371\/journal.pone.0201086","journal-title":"PloS one"},{"issue":"1","key":"7135_CR21","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s13053-021-00169-y","volume":"19","author":"A Savanevich","year":"2021","unstructured":"Savanevich A, Ashuryk O, Cybulski C, Lubi\u0144ski J, Gronwald J (2021) BRCA1 and BRCA2 mutations in ovarian cancer patients from Belarus: update. Hered Cancer Clin Pract 19(1):13. https:\/\/doi.org\/10.1186\/s13053-021-00169-y","journal-title":"Hered Cancer Clin Pract"},{"issue":"2","key":"7135_CR22","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1007\/s10549-022-06782-2","volume":"197","author":"A Kechin","year":"2023","unstructured":"Kechin A, Boyarskikh U, Barinov A, Tanas A, Kazakova S, Zhevlova A, Khrapov E, Subbotin S, Mishukova O, Kekeeva T, Demidova I, Filipenko M (2023) A spectrum of BRCA1 and BRCA2 germline deleterious variants in ovarian cancer in Russia. Breast Cancer Res Treat 197(2):387\u2013395. https:\/\/doi.org\/10.1007\/s10549-022-06782-2","journal-title":"Breast Cancer Res Treat"},{"issue":"5","key":"7135_CR23","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1002\/humu.23406","volume":"39","author":"TR Rebbeck","year":"2018","unstructured":"Rebbeck TR, Friebel TM, Friedman E, Hamann U, Huo D, Kwong A, Olah E, Olopade OI, Solano AR, Teo SH et al (2018) Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. Hum Mutat 39(5):593\u2013620. https:\/\/doi.org\/10.1002\/humu.23406","journal-title":"Hum Mutat"},{"issue":"11","key":"7135_CR24","doi-asserted-by":"publisher","first-page":"2505","DOI":"10.1093\/carcin\/bgt272","volume":"34","author":"M Infante","year":"2013","unstructured":"Infante M, Dur\u00e1n M, Acedo A, S\u00e1nchez-Tapia EM, D\u00edez-G\u00f3mez B, Barroso A, Garc\u00eda-Gonz\u00e1lez M, Feliubadal\u00f3 L, Lasa A, de la Hoya M, Esteban-Carde\u00f1osa E, D\u00edez O, Mart\u00ednez-Bouzas C, Godino J, Teul\u00e9 A, Osorio A, Lastra E, Gonz\u00e1lez-Sarmiento R, Miner C, Velasco EA (2013) The highly prevalent BRCA2 mutation c.2808_2811del (3036delACAA) is located in a mutational hotspot and has multiple origins. Carcinogenesis 34(11):2505\u20132511. https:\/\/doi.org\/10.1093\/carcin\/bgt272","journal-title":"Carcinogenesis"},{"issue":"5","key":"7135_CR25","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1086\/375033","volume":"72","author":"A Antoniou","year":"2003","unstructured":"Antoniou A, Pharoah PD, Narod S, Risch HA, Eyfjord JE, Hopper JL, Loman N, Olsson H, Johannsson O, Borg A, Pasini B, Radice P, Manoukian S, Eccles DM, Tang N, Olah E, Anton-Culver H, Warner E, Lubinski J, Gronwald J, Gorski B, Tulinius H, Thorlacius S, Eerola H, Nevanlinna H, Syrj\u00e4koski K, Kallioniemi OP, Thompson D, Evans C, Peto J, Lalloo F, Evans DG, Easton DF (2003) Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies. Am J Hum Genet 72(5):1117\u20131130. https:\/\/doi.org\/10.1086\/375033","journal-title":"Am J Hum Genet"},{"issue":"11","key":"7135_CR26","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1200\/JCO.2006.09.1066","volume":"25","author":"S Chen","year":"2007","unstructured":"Chen S, Parmigiani G (2007) Meta-analysis of BRCA1 and BRCA2 penetrance. J Clin Oncol 25(11):1329\u20131333. https:\/\/doi.org\/10.1200\/JCO.2006.09.1066","journal-title":"J Clin Oncol"},{"issue":"13","key":"7135_CR27","doi-asserted-by":"publisher","first-page":"1347","DOI":"10.1001\/jama.2014.5985","volume":"313","author":"TR Rebbeck","year":"2015","unstructured":"Rebbeck TR, Mitra N, Wan F, Sinilnikova OM, Healey S, McGuffog L, Mazoyer S, Chenevix-Trench G, Easton DF, Antoniou AC et al (2015) Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. JAMA 313(13):1347\u20131361. https:\/\/doi.org\/10.1001\/jama.2014.5985","journal-title":"JAMA"},{"issue":"1","key":"7135_CR28","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/s41439-021-00140-2","volume":"8","author":"MM Moradian","year":"2021","unstructured":"Moradian MM, Babikyan DT, Markarian S, Petrosyan JG, Avanesian N, Arutunyan T, Sarkisian TF (2021) Germline mutational spectrum in Armenian breast cancer patients suspected of hereditary breast and ovarian cancer. Hum Genome Var 8(1):9. https:\/\/doi.org\/10.1038\/s41439-021-00140-2","journal-title":"Hum Genome Var"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-023-07135-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10549-023-07135-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-023-07135-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T14:04:40Z","timestamp":1705154680000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10549-023-07135-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,18]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["7135"],"URL":"https:\/\/doi.org\/10.1007\/s10549-023-07135-3","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3200216\/v1","asserted-by":"object"}]},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,18]]},"assertion":[{"value":"26 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Ethics Committee in the N.N. Petrov Institute of Oncology conducted in accordance with the Declaration of Helsinki protocol. All patients gave informed consent for the collection and use of their data for a scientific purpose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from the parents.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}