{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T09:07:00Z","timestamp":1784020020659,"version":"3.55.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"The \"National Administration of Traditional Chinese Medicine High-level Construction and Double First-Class\" Discipline Development Support Fund of Heilongjiang University of Chinese Medicine","award":["GJJGSPZDXK31015"],"award-info":[{"award-number":["GJJGSPZDXK31015"]}]},{"name":"Exploration Project on the 'Integrated Two-Wing\u2019 Operation Model of the Provincial TCM Oncology Diagnosis and Treatment Center","award":["2020GSP07"],"award-info":[{"award-number":["2020GSP07"]}]},{"name":"Research Project on Inheriting Academic Experience of National TCM Master Duan Fujin in Treating Malignant Tumors Based on Intelligent TCM Technology","award":["GY2022-05"],"award-info":[{"award-number":["GY2022-05"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Breast Cancer Res Treat"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s10549-026-07980-y","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T09:48:52Z","timestamp":1778233732000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative efficacy of prevention strategies for oral mucositis in breast cancer patients: a network meta-analysis"],"prefix":"10.1007","volume":"217","author":[{"given":"Qianxi","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruhuai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luyi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songjiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,8]]},"reference":[{"key":"7980_CR1","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.breast.2022.08.010","volume":"66","author":"M Arnold","year":"2022","unstructured":"Arnold M, Morgan E, Rumgay H, Mafra A, Singh D, Laversanne M et al (2022) Current and future burden of breast cancer: Global statistics for 2020 and 2040. Breast 66:15\u201323. https:\/\/doi.org\/10.1016\/j.breast.2022.08.010","journal-title":"Breast"},{"issue":"1","key":"7980_CR2","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1038\/s41392-024-02108-4","volume":"10","author":"X Xiong","year":"2025","unstructured":"Xiong X, Zheng LW, Ding Y, Chen YF, Cai YW, Wang LP et al (2025) Breast cancer: pathogenesis and treatments. Signal Transduct Target Ther 10(1):49. https:\/\/doi.org\/10.1038\/s41392-024-02108-4","journal-title":"Signal Transduct Target Ther"},{"key":"7980_CR3","doi-asserted-by":"publisher","first-page":"107534","DOI":"10.1016\/j.phrs.2024.107534","volume":"210","author":"R Roskoski","year":"2024","unstructured":"Roskoski R (2024) Jr. Targeted and cytotoxic inhibitors used in the treatment of breast cancer. Pharmacol Res 210:107534. https:\/\/doi.org\/10.1016\/j.phrs.2024.107534","journal-title":"Pharmacol Res"},{"key":"7980_CR4","doi-asserted-by":"publisher","first-page":"956464","DOI":"10.3389\/fonc.2022.956464","volume":"12","author":"H Xu","year":"2022","unstructured":"Xu H, Wang Y, Han Y, Wu Y, Wang J, Xu B (2022) CDK4\/6 inhibitors versus PI3K\/AKT\/mTOR inhibitors in women with hormone receptor-positive, HER2-negative metastatic breast cancer: An updated systematic review and network meta-analysis of 28 randomized controlled trials. Front Oncol 12:956464. https:\/\/doi.org\/10.3389\/fonc.2022.956464","journal-title":"Front Oncol"},{"key":"7980_CR5","doi-asserted-by":"publisher","first-page":"949071","DOI":"10.3389\/fonc.2022.949071","volume":"12","author":"I Klymiuk","year":"2022","unstructured":"Klymiuk I, Bilgilier C, Mahnert A, Prokesch A, Heininger C, Brandl I et al (2022) Chemotherapy-associated oral microbiome changes in breast cancer patients. Front Oncol 12:949071. https:\/\/doi.org\/10.3389\/fonc.2022.949071","journal-title":"Front Oncol"},{"issue":"9","key":"7980_CR6","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1007\/s00520-025-09805-y","volume":"33","author":"H Rugo","year":"2025","unstructured":"Rugo H, Bardia A, Bruno DS, Ernani V, Hamilton E, Heist R et al (2025) US expert Delphi consensus on the prevention and management of stomatitis in patients treated with datopotamab deruxtecan. Support Care Cancer 33(9):756. https:\/\/doi.org\/10.1007\/s00520-025-09805-y","journal-title":"Support Care Cancer"},{"issue":"3","key":"7980_CR7","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1093\/annonc\/mdv595","volume":"27","author":"HS Rugo","year":"2016","unstructured":"Rugo HS, Hortobagyi GN, Yao J, Pavel M, Ravaud A, Franz D et al (2016) Meta-analysis of stomatitis in clinical studies of everolimus: incidence and relationship with efficacy. Ann Oncol 27(3):519\u2013525. https:\/\/doi.org\/10.1093\/annonc\/mdv595","journal-title":"Ann Oncol"},{"key":"7980_CR8","doi-asserted-by":"publisher","unstructured":"Parra-Rojas S, Vel\u00e1zquez-Cay\u00f3n RT, Ciortan-Pop ME, Martins MD, Cassol Spanemberg J (2025) Preventive photobiomodulation for chemotherapy-induced oral mucositis: a systematic review of randomized clinical trials. Biomedicines 13(2). https:\/\/doi.org\/10.3390\/biomedicines13020268","DOI":"10.3390\/biomedicines13020268"},{"issue":"9","key":"7980_CR9","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1634\/theoncologist.2018-0340","volume":"24","author":"VE Jones","year":"2019","unstructured":"Jones VE, McIntyre KJ, Paul D, Wilks ST, Ondreyco SM, Sedlacek S et al (2019) Evaluation of Miracle Mouthwash plus Hydrocortisone Versus Prednisolone Mouth Rinses as Prophylaxis for Everolimus-Associated Stomatitis: A Randomized Phase II Study. Oncologist 24(9):1153\u20131158. https:\/\/doi.org\/10.1634\/theoncologist.2018-0340","journal-title":"Oncologist"},{"key":"7980_CR10","doi-asserted-by":"publisher","unstructured":"Kuba S, Maeda S, Shibata K, Soutome S, Yamanouchi K, Matsumoto M (2023) Efficacy and, safety of a dexamethasone-based mouthwash, to prevent chemotherapy-induced stomatitis in women with breast cancer: a multicentre, open-label, randomised phase 2 study. J Evid Based Dent Pract 23(3):101896. https:\/\/doi.org\/10.1016\/j.jebdp.2023.101896","DOI":"10.1016\/j.jebdp.2023.101896"},{"key":"7980_CR11","doi-asserted-by":"publisher","first-page":"104751","DOI":"10.1016\/j.oraloncology.2020.104751","volume":"107","author":"X Zhang","year":"2020","unstructured":"Zhang X, Sun D, Qin N, Liu M, Zhang J, Li X (2020) Comparative prevention potential of 10 mouthwashes on intolerable oral mucositis in cancer patients: A Bayesian network analysis. Oral Oncol 107:104751. https:\/\/doi.org\/10.1016\/j.oraloncology.2020.104751","journal-title":"Oral Oncol"},{"issue":"1","key":"7980_CR12","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1186\/s12903-018-0696-y","volume":"18","author":"C Yang","year":"2018","unstructured":"Yang C, Liu L, Shi H, Zhang Y (2018) Psychological problems and quality of life of patients with oral mucosal diseases: a preliminary study in Chinese population. BMC Oral Health 18(1):226. https:\/\/doi.org\/10.1186\/s12903-018-0696-y","journal-title":"BMC Oral Health"},{"issue":"3","key":"7980_CR13","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1200\/jop.19.00652","volume":"16","author":"TJ Brown","year":"2020","unstructured":"Brown TJ, Gupta A (2020) Management of Cancer Therapy-Associated Oral Mucositis. JCO Oncol Pract 16(3):103\u2013109. https:\/\/doi.org\/10.1200\/jop.19.00652","journal-title":"JCO Oncol Pract"},{"key":"7980_CR14","doi-asserted-by":"publisher","first-page":"695","DOI":"10.2147\/imcrj.S476377","volume":"17","author":"ASW Rajasa","year":"2024","unstructured":"Rajasa ASW, Hidayat W (2024) Oral Lesion Management in Juvenile SLE with Hepatosplenomegaly. Int Med Case Rep J 17:695\u2013702. https:\/\/doi.org\/10.2147\/imcrj.S476377","journal-title":"Int Med Case Rep J"},{"key":"7980_CR15","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/j.actbio.2025.01.013","volume":"194","author":"Y Chen","year":"2025","unstructured":"Chen Y, Lei K, Li Y, Mu Z, Chu T, Hu J et al (2025) Synergistic effects of NO\/H(2)S gases on antibacterial, anti-inflammatory, and analgesic properties in oral ulcers using a gas-releasing nanoplatform. Acta Biomater 194:288\u2013304. https:\/\/doi.org\/10.1016\/j.actbio.2025.01.013","journal-title":"Acta Biomater"},{"issue":"1","key":"7980_CR16","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3322\/caac.21704","volume":"72","author":"S Elad","year":"2022","unstructured":"Elad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST (2022) The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies. CA Cancer J Clin 72(1):57\u201377. https:\/\/doi.org\/10.3322\/caac.21704","journal-title":"CA Cancer J Clin"},{"key":"7980_CR17","doi-asserted-by":"publisher","unstructured":"Meric-Bernstam F, Bardia A, Bossi P, Bianchini G, Gatlin F, Lalla RV et al (2025) Prophylaxis, clinical management, and monitoring of datopotamab deruxtecan-associated oral mucositis\/stomatitis. Oncologist 30(3). https:\/\/doi.org\/10.1093\/oncolo\/oyaf031","DOI":"10.1093\/oncolo\/oyaf031"},{"issue":"2","key":"7980_CR18","doi-asserted-by":"publisher","first-page":"2018","DOI":"10.1097\/js9.0000000000002147","volume":"111","author":"Z Juan","year":"2025","unstructured":"Juan Z, Chen J, Ding B, Yongping L, Cai H, Chen H et al (2025) Probiotics prevent pegylated liposomal doxorubicin-associated hand-foot syndrome and oral mucositis of breast cancer patients following surgery and chemotherapy: a randomized placebo-controlled trial. Int J Surg 111(2):2018\u20132030. https:\/\/doi.org\/10.1097\/js9.0000000000002147","journal-title":"Int J Surg"},{"key":"7980_CR19","doi-asserted-by":"publisher","unstructured":"Piredda M, Facchinetti G, Biagioli V, Giannarelli D, Armento G, Tonini G et al (2017) Propolis in the prevention of oral mucositis in breast cancer patients receiving adjuvant chemotherapy: a pilot randomised controlled trial. Eur J Cancer Care (Engl) 26(6). https:\/\/doi.org\/10.1111\/ecc.12757","DOI":"10.1111\/ecc.12757"},{"key":"7980_CR20","doi-asserted-by":"publisher","unstructured":"Peterson DE, Jones JB, Petit RG 2 (2007) Randomized, placebo-controlled trial of Saforis for prevention and treatment of oral mucositis in breast cancer patients receiving anthracycline-based chemotherapy. Cancer 109(2):322\u2013331. https:\/\/doi.org\/10.1002\/cncr.22384","DOI":"10.1002\/cncr.22384"},{"issue":"1","key":"7980_CR21","doi-asserted-by":"publisher","first-page":"e10533","DOI":"10.34172\/npj.2022.10533","volume":"12","author":"M Roayaei","year":"2023","unstructured":"Roayaei M, Andalib Z, Akhavan A (2023) The effect of oral zinc sulfate on prevention of chemotherapy-induced oral mucositis in breast cancer patients treated with adriamycin and cyclophosphamide; a double-blind randomized clinical trial. J Nephropharmacol 12(1):e10533\u2013e. https:\/\/doi.org\/10.34172\/npj.2022.10533","journal-title":"J Nephropharmacol"},{"issue":"4Supplement","key":"7980_CR22","first-page":"P1","volume":"79","author":"N Niikura","year":"2019","unstructured":"Niikura N, Nakatukasa K, Amamiya T, Watanabe K-i, Hata H, Kikawa Y et al (2019) Abstract P1-11-01: Oral care evaluation to prevent oral mucositis in estrogen receptor positive metastatic breast cancer patients treated with everolimus (Oral Care-BC): A randomized controlled phase III trial. Cancer Res 79(4Supplement):P1. 11-01-P1-11-01","journal-title":"Cancer Res"},{"key":"7980_CR23","doi-asserted-by":"publisher","first-page":"105906","DOI":"10.1016\/j.ijsu.2021.105906","volume":"88","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. Int J Surg 88:105906. https:\/\/doi.org\/10.1016\/j.ijsu.2021.105906","journal-title":"Int J Surg"},{"issue":"11","key":"7980_CR24","doi-asserted-by":"publisher","first-page":"777","DOI":"10.7326\/m14-2385","volume":"162","author":"B Hutton","year":"2015","unstructured":"Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C et al (2015) The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Ann Intern Med 162(11):777\u2013784. https:\/\/doi.org\/10.7326\/m14-2385","journal-title":"Ann Intern Med"},{"issue":"9","key":"7980_CR25","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1093\/jjco\/hyw077","volume":"46","author":"N Niikura","year":"2016","unstructured":"Niikura N, Ota Y, Hayashi N, Naito M, Kashiwabara K, Watanabe K et al (2016) Evaluation of oral care to prevent oral mucositis in estrogen receptor-positive metastatic breast cancer patients treated with everolimus (Oral Care-BC): randomized controlled phase III trial. Jpn J Clin Oncol 46(9):879\u2013882. https:\/\/doi.org\/10.1093\/jjco\/hyw077","journal-title":"Jpn J Clin Oncol"},{"issue":"9","key":"7980_CR26","first-page":"655","volume":"8","author":"W Van der Vliet","year":"1989","unstructured":"Van der Vliet W, Erlichman C, Elhakim T (1989) Allopurinol mouthwash for prevention of fluorouracil-induced stomatitis. Clin Pharm 8(9):655\u2013658","journal-title":"Clin Pharm"},{"key":"7980_CR27","doi-asserted-by":"crossref","unstructured":"Iwamoto M, NU, Matsuda J, Kawaguchi K, Terasawa R, Sato N (2016) Randomized phase II study of Hangeshashinto (TJ-14) for chemotherapy induced oral mucositis in patients with breast cancer (Hangesha-B study). Cancer Res 76(4):Suppl1","DOI":"10.1158\/1538-7445.SABCS15-OT3-02-01"},{"key":"7980_CR28","unstructured":"Ajmera A DWaSL. (2014) Stomatitis prevention during everolimus\/exemestane treatment for metastatic breast cancer: a phase 2 study of steroid-based mouthwash. Oncol Nurs Forum 41(2):E96\u2013E7"},{"key":"7980_CR29","unstructured":"Petit RGPD (2004) AES-14 (SaforisT) treatment reduces the severity and duration of oral mucositis in three common breast cancer chemotherapy regimens. 8:S230"},{"issue":"2","key":"7980_CR30","doi-asserted-by":"publisher","first-page":"e033446","DOI":"10.1136\/bmjopen-2019-033446","volume":"10","author":"S Kuba","year":"2020","unstructured":"Kuba S, Yamanouchi K, Matsumoto M, Maeda S, Hatachi T, Sakiko S et al (2020) Study protocol for efficacy and safety of steroid-containing mouthwash to prevent chemotherapy-induced stomatitis in women with breast cancer: a multicentre, open-label, randomised phase 2 study. BMJ Open 10(2):e033446. https:\/\/doi.org\/10.1136\/bmjopen-2019-033446","journal-title":"BMJ Open"},{"issue":"2","key":"7980_CR31","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1093\/jjco\/hyae136","volume":"55","author":"S Kuba","year":"2025","unstructured":"Kuba S, Soutome S, Hagiwara Y, Kikawa Y, Iwamoto T, Sangai T et al (2025) A randomized phase III study evaluating dexamethasone-based mouthwash to prevent chemotherapy-induced stomatitis in patients with breast cancer. Jpn J Clin Oncol 55(2):172\u2013175. https:\/\/doi.org\/10.1093\/jjco\/hyae136","journal-title":"Jpn J Clin Oncol"},{"key":"7980_CR32","doi-asserted-by":"crossref","unstructured":"de F\u00e1tima L, Ferreira M, de Carvalho FB, de Oliveira SCPS, Monteiro J, Santos G, Gesteira M et al (2013) Use of laser photomodulation in the evolution of oral mucositis associated to cyclophosphamide, Methotrexate, 5-Fluouracil - CMF in 5 Fluouracil\u2009+\u2009Adriamycin\u2009+\u2009Cyclophosphamide - FAC chemotherapy protocols in patients with breast cancer. SPIE BiOS. SPIE","DOI":"10.1117\/12.2005274"},{"issue":"3","key":"7980_CR33","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1159\/000242593","volume":"50","author":"RJ Frampton","year":"1986","unstructured":"Frampton RJ, Yardley RW, MacMahon RA (1986) Changes in plasma amino acids in the developing chick. Biol Neonate 50(3):154\u2013159. https:\/\/doi.org\/10.1159\/000242593","journal-title":"Biol Neonate"},{"issue":"2","key":"7980_CR34","doi-asserted-by":"publisher","first-page":"e223","DOI":"10.1634\/theoncologist.2019-0382","volume":"25","author":"N Niikura","year":"2020","unstructured":"Niikura N, Nakatukasa K, Amemiya T, Watanabe KI, Hata H, Kikawa Y et al (2020) Oral Care Evaluation to Prevent Oral Mucositis in Estrogen Receptor-Positive Metastatic Breast Cancer Patients Treated with Everolimus (Oral Care-BC): A Randomized Controlled Phase III Trial. Oncologist 25(2):e223\u2013e30. https:\/\/doi.org\/10.1634\/theoncologist.2019-0382","journal-title":"Oncologist"},{"issue":"1","key":"7980_CR35","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/s13643-020-01318-5","volume":"9","author":"C Benea","year":"2020","unstructured":"Benea C, Turner KA, Roseman M, Bero LA, Lexchin J, Turner EH et al (2020) Reporting of financial conflicts of interest in meta-analyses of drug trials published in high-impact medical journals: comparison of results from 2017 to 2018 and 2009. Syst Rev 9(1):77. https:\/\/doi.org\/10.1186\/s13643-020-01318-5","journal-title":"Syst Rev"},{"issue":"7","key":"7980_CR36","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1111\/j.1753-4887.2008.00049.x","volume":"66","author":"UC Natchu","year":"2008","unstructured":"Natchu UC, Fataki MR, Fawzi WW (2008) Zinc as an adjunct for childhood pneumonia - interpreting early results. Nutr Rev 66(7):398\u2013405. https:\/\/doi.org\/10.1111\/j.1753-4887.2008.00049.x","journal-title":"Nutr Rev"},{"key":"7980_CR37","doi-asserted-by":"publisher","unstructured":"Ahmad R, Shaju R, Atfi A, Razzaque MS (2024) Zinc and diabetes: a connection between micronutrient and metabolism. Cells 13(16). https:\/\/doi.org\/10.3390\/cells13161359","DOI":"10.3390\/cells13161359"},{"key":"7980_CR38","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1186\/1479-5876-8-118","volume":"8","author":"E John","year":"2010","unstructured":"John E, Laskow TC, Buchser WJ, Pitt BR, Basse PH, Butterfield LH et al (2010) Zinc in innate and adaptive tumor immunity. J Transl Med 8:118. https:\/\/doi.org\/10.1186\/1479-5876-8-118","journal-title":"J Transl Med"},{"key":"7980_CR39","doi-asserted-by":"publisher","unstructured":"Hewlings S, Kalman D (2020) A Review of Zinc-L-carnosine and its positive effects on oral mucositis, taste disorders, and gastrointestinal disorders. Nutrients 12(3) https:\/\/doi.org\/10.3390\/nu12030665","DOI":"10.3390\/nu12030665"}],"container-title":["Breast Cancer Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-026-07980-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10549-026-07980-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10549-026-07980-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T08:30:18Z","timestamp":1784017818000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10549-026-07980-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,8]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["7980"],"URL":"https:\/\/doi.org\/10.1007\/s10549-026-07980-y","relation":{},"ISSN":["0167-6806","1573-7217"],"issn-type":[{"value":"0167-6806","type":"print"},{"value":"1573-7217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,8]]},"assertion":[{"value":"10 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"31"}}