{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:49:27Z","timestamp":1788778167691,"version":"build-2803163510"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,9,30]],"date-time":"2007-09-30T00:00:00Z","timestamp":1191110400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1007\/s10552-007-9067-8","type":"journal-article","created":{"date-parts":[[2007,9,29]],"date-time":"2007-09-29T07:56:47Z","timestamp":1191052607000},"page":"33-41","source":"Crossref","is-referenced-by-count":58,"title":["Risk factors of biliary tract cancer in a large-scale population-based cohort study in Japan (JPHC study); with special focus on cholelithiasis, body mass index, and their effect modification"],"prefix":"10.1007","volume":"19","author":[{"given":"Seiji","family":"Ishiguro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manami","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norie","family":"Kurahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoki","family":"Iwasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shizuka","family":"Sasazuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichiro","family":"Tsugane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,9,30]]},"reference":[{"key":"9067_CR1","first-page":"125","volume":"32","author":"I Plesko","year":"1985","unstructured":"Plesko I, Somogyi J, Dimitrova E, Kiss J, Vlasak V (1985) Epidemiological features of biliary tract cancer incidence in Slovakia. Neoplasma 32:125\u2013134","journal-title":"Neoplasma"},{"key":"9067_CR2","first-page":"113","volume":"41","author":"J Nectoux","year":"1993","unstructured":"Nectoux J, Coleman MP (1993) Trends in biliary tract cancer. Rev Epidemiol Sante Publique 41:113\u2013122","journal-title":"Rev Epidemiol Sante Publique"},{"key":"9067_CR3","first-page":"125","volume":"19\u201320","author":"S Tominaga","year":"1994","unstructured":"Tominaga S, Kuroishi T (1994) Biliary tract cancer. Cancer Surv 19\u201320:125\u2013137","journal-title":"Cancer Surv"},{"key":"9067_CR4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1053\/sonc.2002.37377","volume":"29","author":"T Okusaka","year":"2002","unstructured":"Okusaka T (2002) Chemotherapy for biliary tract cancer in Japan. Semin Oncol 29:51\u201353","journal-title":"Semin Oncol"},{"key":"9067_CR5","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1038\/sj.bjc.6602208","volume":"91","author":"H Ueno","year":"2004","unstructured":"Ueno H, Okusaka T, Ikeda M, Takezako Y, Morizane C (2004) Phase II study of S-1 in patients with advanced biliary tract cancer. Br J Cancer 91:1769\u20131774","journal-title":"Br J Cancer"},{"key":"9067_CR6","unstructured":"http:\/\/www.mhlw.go.jp\/toukei\/saikin\/hw\/jinkou\/suii04\/deth11.html"},{"key":"9067_CR7","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1111\/j.1349-7006.1989.tb01629.x","volume":"80","author":"K Kato","year":"1989","unstructured":"Kato K, Akai S, Tominaga S, Kato I (1989) A case\u2013control study of biliary tract cancer in Niigata Prefecture, Japan. Jpn J Cancer Res 80:932\u2013938","journal-title":"Jpn J Cancer Res"},{"key":"9067_CR8","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1093\/jnci\/89.15.1132","volume":"89","author":"WA Zatonski","year":"1997","unstructured":"Zatonski WA, Lowenfels AB, Boyle P et al (1997) Epidemiologic aspects of gallbladder cancer: a case\u2013control study of the SEARCH Program of the International Agency for Research on Cancer. J Natl Cancer Inst 89:1132\u20131138","journal-title":"J Natl Cancer Inst"},{"key":"9067_CR9","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1572-0241.1999.00786.x","volume":"94","author":"ZR Khan","year":"1999","unstructured":"Khan ZR, Neugut AI, Ahsan H, Chabot JA (1999) Risk factors for biliary tract cancers. Am J Gastroenterol 94:149\u2013152","journal-title":"Am J Gastroenterol"},{"key":"9067_CR10","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/BF01830247","volume":"5","author":"WH Chow","year":"1994","unstructured":"Chow WH, McLaughlin JK, Menck HR, Mack TM (1994) Risk factors for extrahepatic bile duct cancers: Los Angeles County, California (USA). Cancer Causes Control 5:267\u2013272","journal-title":"Cancer Causes Control"},{"key":"9067_CR11","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1023\/A:1026627129702","volume":"44","author":"FX Caroli-Bosc","year":"1999","unstructured":"Caroli-Bosc FX, Deveau C, Harris A et al (1999) Prevalence of cholelithiasis: results of an epidemiologic investigation in Vidauban, southeast France. General Practitioner\u2019s Group of Vidauban. Dig Dis Sci 44:1322\u20131329","journal-title":"Dig Dis Sci"},{"key":"9067_CR12","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/sj.ijo.0801961","volume":"26","author":"S Tsugane","year":"2002","unstructured":"Tsugane S, Sasaki S, Tsubono Y (2002) Under- and overweight impact on mortality among middle-aged Japanese men and women: a 10-y follow-up of JPHC study cohort I. Int J Obes Relat Metab Disord 26:529\u2013537","journal-title":"Int J Obes Relat Metab Disord"},{"key":"9067_CR13","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1023\/B:CACO.0000036177.77953.47","volume":"15","author":"M Inoue","year":"2004","unstructured":"Inoue M, Sobue T, Tsugane S (2004) Impact of body mass index on the risk of total cancer incidence and mortality among middle-aged Japanese: data from a large-scale population-based cohort study\u2014the JPHC study. Cancer Causes Control 15:671\u2013680","journal-title":"Cancer Causes Control"},{"key":"9067_CR14","volume-title":"International classification of diseases for oncology","author":"World Health Organization","year":"2000","unstructured":"World Health Organization (2000) International classification of diseases for oncology, 3rd edn. WHO, Geneva","edition":"3"},{"key":"9067_CR15","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1111\/j.1572-0241.2007.01104.x","volume":"102","author":"YH Shaib","year":"2007","unstructured":"Shaib YH, El-Serag HB, Nooka AK et al (2007) Risk factors for intrahepatic and extrahepatic cholangiocarcinoma: a hospital-based case\u2013control study. Am J Gastroenterol 102:1016\u20131021","journal-title":"Am J Gastroenterol"},{"key":"9067_CR16","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1002\/ijc.22375","volume":"120","author":"AW Hsing","year":"2007","unstructured":"Hsing AW, Gao YT, McGlynn KA et al (2007) Biliary tract cancer and stones in relation to chronic liver conditions: a population-based study in Shanghai, China. Int J Cancer 120:1981\u20131985","journal-title":"Int J Cancer"},{"key":"9067_CR17","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1093\/jnci\/djj234","volume":"98","author":"TM Welzel","year":"2006","unstructured":"Welzel TM, McGlynn KA, Hsing AW, O\u2019Brien TR, Pfeiffer RM (2006) Impact of classification of hilar cholangiocarcinomas (Klatskin tumors) on the incidence of intra- and extrahepatic cholangiocarcinoma in the United States. J Natl Cancer Inst 98:873\u2013875","journal-title":"J Natl Cancer Inst"},{"key":"9067_CR18","volume-title":"Stata statistical software VCS","author":"Stata Corporation","year":"2005","unstructured":"Stata Corporation (2005) Stata statistical software VCS. Stata Corporation, Tx"},{"key":"9067_CR19","first-page":"5165","volume":"45","author":"BL Strom","year":"1985","unstructured":"Strom BL, Hibberd PL, Soper KA, Stolley PD, Nelson WL (1985) International variations in epidemiology of cancers of the extrahepatic biliary tract. Cancer Res 45:5165\u20135168","journal-title":"Cancer Res"},{"key":"9067_CR20","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1136\/jech.41.4.344","volume":"41","author":"P Renard","year":"1987","unstructured":"Renard P, Boutron MC, Faivre J et al (1987) Biliary tract cancers in Cote-d\u2019Or (France): incidence and natural history. J Epidemiol Community Health 41:344\u2013348","journal-title":"J Epidemiol Community Health"},{"key":"9067_CR21","doi-asserted-by":"crossref","first-page":"30","DOI":"10.7326\/0003-4819-107-1-30","volume":"107","author":"A Maringhini","year":"1987","unstructured":"Maringhini A, Moreau JA, Melton LJ 3rd, Hench VS, Zinsmeister AR, DiMagno EP (1987) Gallstones, gallbladder cancer, and other gastrointestinal malignancies. An epidemiologic study in Rochester, Minnesota. Ann Intern Med 107:30\u201335","journal-title":"Ann Intern Med"},{"key":"9067_CR22","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1002\/ijc.2910510508","volume":"51","author":"WA Zatonski","year":"1992","unstructured":"Zatonski WA, La Vecchia C, Przewozniak K, Maisonneuve P, Lowenfels AB, Boyle P (1992) Risk factors for gallbladder cancer: a Polish case\u2013control study. Int J Cancer 51:707\u2013711","journal-title":"Int J Cancer"},{"key":"9067_CR23","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1038\/sj.bjc.6690101","volume":"79","author":"WH Chow","year":"1999","unstructured":"Chow WH, Johansen C, Gridley G, Mellemkjaer L, Olsen JH, Fraumeni JF Jr (1999) Gallstones, cholecystectomy and risk of cancers of the liver, biliary tract and pancreas. Br J Cancer 79:640\u2013644","journal-title":"Br J Cancer"},{"key":"9067_CR24","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1349-7006.1989.tb02299.x","volume":"80","author":"H Yamagiwa","year":"1989","unstructured":"Yamagiwa H (1989) Mucosal dysplasia of gallbladder: isolated and adjacent lesions to carcinoma. Jpn J Cancer Res 80:238\u2013243","journal-title":"Jpn J Cancer Res"},{"key":"9067_CR25","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1002\/1097-0142(19861015)58:8<1702::AID-CNCR2820580821>3.0.CO;2-Z","volume":"58","author":"GP Dowling","year":"1986","unstructured":"Dowling GP, Kelly JK (1986) The histogenesis of adenocarcinoma of the gallbladder. Cancer 58:1702\u20131708","journal-title":"Cancer"},{"key":"9067_CR26","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1002\/1097-0142(19930915)72:6<1878::AID-CNCR2820720615>3.0.CO;2-2","volume":"72","author":"I Duarte","year":"1993","unstructured":"Duarte I, Llanos O, Domke H, Harz C, Valdivieso V (1993) Metaplasia and precursor lesions of gallbladder carcinoma. Frequency, distribution, and probability of detection in routine histologic samples. Cancer 72:1878\u20131884","journal-title":"Cancer"},{"key":"9067_CR27","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S0344-0338(82)80034-4","volume":"174","author":"U Ziegler","year":"1982","unstructured":"Ziegler U, Palme G, Merker HJ (1982) Morphological alterations in epithelial cells of the mouse gallbladder 30\u00a0hours after treatment with lithogenic diet. Pathol Res Pract 174:116\u2013130","journal-title":"Pathol Res Pract"},{"key":"9067_CR28","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3109\/00365528809093853","volume":"23","author":"V Skar","year":"1988","unstructured":"Skar V, Skar AG, Stromme JH (1988) Beta-glucuronidase activity related to bacterial growth in common bile duct bile in gallstone patients. Scand J Gastroenterol 23:83\u201390","journal-title":"Scand J Gastroenterol"},{"key":"9067_CR29","first-page":"134","volume":"39","author":"B Abayli","year":"2005","unstructured":"Abayli B, Colakoglu S, Serin M et al (2005) Helicobacter pylori in the etiology of cholesterol gallstones. J Clin Gastroenterol 39:134\u2013137","journal-title":"J Clin Gastroenterol"},{"key":"9067_CR30","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1002\/cncr.10893","volume":"95","author":"M Bulajic","year":"2002","unstructured":"Bulajic M, Maisonneuve P, Schneider-Brachert W et al (2002) Helicobacter pylori and the risk of benign and malignant biliary tract disease. Cancer 95:1946\u20131953","journal-title":"Cancer"},{"key":"9067_CR31","doi-asserted-by":"crossref","first-page":"3089","DOI":"10.1002\/ijc.21748","volume":"118","author":"XH Zhang","year":"2006","unstructured":"Zhang XH, Andreotti G, Gao YT et al (2006) Tea drinking and the risk of biliary tract cancers and biliary stones: a population-based case\u2013control study in Shanghai, China. Int J Cancer 118:3089\u20133094","journal-title":"Int J Cancer"},{"key":"9067_CR32","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1002\/1097-0142(19951115)76:10<1747::AID-CNCR2820761011>3.0.CO;2-L","volume":"76","author":"BL Strom","year":"1995","unstructured":"Strom BL, Soloway RD, Rios-Dalenz JL et al (1995) Risk factors for gallbladder cancer. An international collaborative case\u2013control study. Cancer 76:1747\u20131756","journal-title":"Cancer"},{"key":"9067_CR33","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/ijc.10716","volume":"102","author":"I Serra","year":"2002","unstructured":"Serra I, Yamamoto M, Calvo A et al (2002) Association of chili pepper consumption, low socioeconomic status and longstanding gallstones with gallbladder cancer in a Chilean population. Int J Cancer 102:407\u2013411","journal-title":"Int J Cancer"},{"key":"9067_CR34","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/j.1349-7006.2004.tb03328.x","volume":"95","author":"K Yagyu","year":"2004","unstructured":"Yagyu K, Lin Y, Obata Y et al (2004) Bowel movement frequency, medical history and the risk of gallbladder cancer death: a cohort study in Japan. Cancer Sci 95:674\u2013678","journal-title":"Cancer Sci"},{"key":"9067_CR35","first-page":"386","volume":"84","author":"W Kimura","year":"1989","unstructured":"Kimura W, Shimada H, Kuroda A, Morioka Y (1989) Carcinoma of the gallbladder and extrahepatic bile duct in autopsy cases of the aged, with special reference to its relationship to gallstones. Am J Gastroenterol 84:386\u2013390","journal-title":"Am J Gastroenterol"},{"key":"9067_CR36","unstructured":"World Health Organization (2003) WHO Technical Reports Series 916. Diet NatPoCDRoaJWFECG, Switzerland: World Health Organization (2003) WHO Technical Reports Series 916. Diet, Nutrition and the Prevention of Chronic Disease. Report of a Joint WHO\/FAO Expert Consultation"},{"key":"9067_CR37","doi-asserted-by":"crossref","first-page":"4742","DOI":"10.1200\/JCO.2005.11.726","volume":"23","author":"SW Oh","year":"2005","unstructured":"Oh SW, Yoon YS, Shin SA (2005) Effects of excess weight on cancer incidences depending on cancer sites and histologic findings among men: Korea National Health Insurance Corporation Study. J Clin Oncol 23:4742\u20134754","journal-title":"J Clin Oncol"},{"key":"9067_CR38","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1158\/0008-5472.CAN-06-1078","volume":"67","author":"F Yang","year":"2007","unstructured":"Yang F, Huang X, Yi T, Yen Y, Moore DD, Huang W (2007) Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor. Cancer Res 67:863\u2013867","journal-title":"Cancer Res"},{"key":"9067_CR39","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1002\/hep.1840200625","volume":"20","author":"CM St George","year":"1994","unstructured":"St George CM, Russell JC, Shaffer EA (1994) Effects of obesity on bile formation and biliary lipid secretion in the genetically obese JCR:LA-corpulent rat. Hepatology 20:1541\u20131547","journal-title":"Hepatology"}],"container-title":["Cancer Causes &amp; Control"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-007-9067-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10552-007-9067-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-007-9067-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T17:05:49Z","timestamp":1559235949000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10552-007-9067-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9,30]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["9067"],"URL":"https:\/\/doi.org\/10.1007\/s10552-007-9067-8","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"value":"0957-5243","type":"print"},{"value":"1573-7225","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9,30]]}}}