{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T21:05:25Z","timestamp":1781989525111,"version":"3.54.5"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T00:00:00Z","timestamp":1523491200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1007\/s10552-018-1028-x","type":"journal-article","created":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T04:23:02Z","timestamp":1523506982000},"page":"519-525","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Interactions of coffee consumption and postmenopausal hormone use in relation to breast cancer risk in UK Biobank"],"prefix":"10.1007","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1626-5340","authenticated-orcid":false,"given":"Lusine","family":"Yaghjyan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannan","family":"Rich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Mai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen M.","family":"Egan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,4,12]]},"reference":[{"key":"1028_CR1","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1093\/jn\/136.1.166","volume":"136","author":"JA Baker","year":"2006","unstructured":"Baker JA, Beehler GP, Sawant AC, Jayaprakash V, McCann SE, Moysich KB (2006) Consumption of coffee, but not black tea, is associated with decreased risk of premenopausal breast cancer. J Nutr 136:166\u2013171","journal-title":"J Nutr"},{"key":"1028_CR2","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1080\/01635581.2013.768348","volume":"65","author":"EC Lowcock","year":"2013","unstructured":"Lowcock EC, Cotterchio M, Anderson LN, Boucher BA, El-Sohemy A (2013) High coffee intake, but not caffeine, is associated with reduced estrogen receptor negative and postmenopausal breast cancer risk with no effect modification by CYP1A2 genotype. Nutr Cancer 65:398\u2013409","journal-title":"Nutr Cancer"},{"key":"1028_CR3","doi-asserted-by":"publisher","first-page":"1979","DOI":"10.1002\/ijc.29569","volume":"137","author":"JK Oh","year":"2015","unstructured":"Oh JK, Sandin S, Strom P, Lof M, Adami HO, Weiderpass E (2015) Prospective study of breast cancer in relation to coffee, tea and caffeine in Sweden. Int J Cancer 137:1979\u20131989","journal-title":"Int J Cancer"},{"key":"1028_CR4","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s13058-015-0521-3","volume":"17","author":"N Bhoo-Pathy","year":"2015","unstructured":"Bhoo-Pathy N, Peeters PHM, Uiterwaal CSPM., Bueno-de-Mesquita HB, Bulgiba AM, Bech BH, Overvad K, Tj\u00f8nneland A, Olsen A, Clavel-Chapelon F, Fagherazzi G, Perquier F, Teucher B, Kaaks R, Sch\u00fctze M, Boeing H, Lagiou P, Orfanos P, Trichopoulou A, Agnoli C, Mattiello A, Palli D, Tumino R, Sacerdote C, van Duijnhoven FJB, Braaten T, Lund E, Skeie G, Redondo M-L, Buckland G, P\u00e9rez MJS, Chirlaque M-D, Ardanaz E, Amiano P, Wirf\u00e4lt E, Wallstr\u00f6m P, Johansson I, Nilsson LM, Khaw K-T, Wareham N, Allen NE, Key TJ, Rinaldi S, Romieu I, Gallo V, Riboli E, van Gils CH (2015) Coffee and tea consumption and risk of pre- and postmenopausal breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study. Breast Cancer Res 17:15","journal-title":"Breast Cancer Res"},{"key":"1028_CR5","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1158\/1055-9965.EPI-15-0246","volume":"24","author":"JS Sisti","year":"2015","unstructured":"Sisti JS, Hankinson SE, Caporaso NE, Gu F, Tamimi RM, Rosner B, Xu X, Ziegler R, Eliassen AH (2015) Caffeine, coffee, and tea intake and urinary estrogens and estrogen metabolites in premenopausal women. Cancer Epidemiol Biomark Prev 24:1174\u20131183","journal-title":"Cancer Epidemiol Biomark Prev"},{"key":"1028_CR6","doi-asserted-by":"publisher","first-page":"2765","DOI":"10.1002\/cncr.24328","volume":"115","author":"J Kotsopoulos","year":"2009","unstructured":"Kotsopoulos J, Eliassen AH, Missmer SA, Hankinson SE, Tworoger SS (2009) Relationship between caffeine intake and plasma sex hormone concentrations in premenopausal and postmenopausal women. Cancer 115:2765\u20132774","journal-title":"Cancer"},{"key":"1028_CR7","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1093\/ajcn\/84.1.95","volume":"84","author":"BL Halvorsen","year":"2006","unstructured":"Halvorsen BL, Carlsen MH, Phillips KM, B\u00f8hn SK, Holte K, Jacobs DR, Blomhoff R (2006) Content of redox-active compounds (ie, antioxidants) in foods consumed in the United States. Am J Clin Nutr 84:95\u2013135","journal-title":"Am J Clin Nutr"},{"key":"1028_CR8","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1097\/FPC.0b013e3283498ecf","volume":"21","author":"N Rahmioglu","year":"2011","unstructured":"Rahmioglu N, Heaton J, Clement G, Gill R, Surdulescu G, Zlobecka K, Hodgkiss D, Ma Y, Hider RC, Smith NW, Ahmadi KR (2011) Genetic epidemiology of induced CYP3A4 activity. Pharmacogenet Genomics 21:642\u2013651","journal-title":"Pharmacogenet Genomics"},{"key":"1028_CR9","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1093\/carcin\/bgi206","volume":"27","author":"WJ Lee","year":"2006","unstructured":"Lee WJ, Zhu BT (2006) Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols. Carcinogenesis 27:269\u2013277","journal-title":"Carcinogenesis"},{"key":"1028_CR10","first-page":"482","volume":"100","author":"J Pozner","year":"1986","unstructured":"Pozner J, Papatestas AE, Fagerstrom R, Schwartz I, Saevitz J, Feinberg M, Aufses AH Jr (1986) Association of tumor differentiation with caffeine and coffee intake in women with breast cancer. Surgery 100:482\u2013488","journal-title":"Surgery"},{"key":"1028_CR11","doi-asserted-by":"publisher","first-page":"2071","DOI":"10.1002\/ijc.23336","volume":"122","author":"D Ganmaa","year":"2008","unstructured":"Ganmaa D, Willett WC, Li TY, Feskanich D, van Dam RM, Lopez-Garcia E, Hunter DJ, Holmes MD (2008) Coffee, tea, caffeine, and risk of breast cancer: a twenty two-year follow-up. Int J Cancer 122:2071\u20132076","journal-title":"Int J Cancer"},{"key":"1028_CR12","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.ygyno.2013.03.014","volume":"129","author":"W Jiang","year":"2013","unstructured":"Jiang W, Wu Y, Jiang X (2013) Coffee and caffeine intake and breast cancer risk: an updated dose-response meta-analysis of 37 published studies. Gynecol Oncol 129:620\u2013629","journal-title":"Gynecol Oncol"},{"key":"1028_CR13","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1093\/jnci\/87.3.190","volume":"87","author":"PG Toniolo","year":"1995","unstructured":"Toniolo PG, Levitz M, Zeleniuch-Jacquotte A, Banerjee S, Koenig KL, Shore RE, Strax P, Pasternack BS (1995) A prospective study of endogenous estrogens and breast cancer in postmenopausal women. J Natl Cancer Inst 87:190\u2013197","journal-title":"J Natl Cancer Inst"},{"key":"1028_CR14","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1002\/ijc.11034","volume":"105","author":"H Yu","year":"2003","unstructured":"Yu H, Shu XO, Shi R, Dai Q, Jin F, Gao YT, Li BD, Zheng W (2003) Plasma sex steroid hormones and breast cancer risk in Chinese women. Int J Cancer 105:92\u201397","journal-title":"Int J Cancer"},{"key":"1028_CR15","doi-asserted-by":"publisher","first-page":"1856","DOI":"10.1093\/jnci\/djh336","volume":"96","author":"SA Missmer","year":"2004","unstructured":"Missmer SA, Eliassen AH, Barbieri RL, Hankinson SE (2004) Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women. J Natl Cancer Inst 96:1856\u20131865","journal-title":"J Natl Cancer Inst"},{"key":"1028_CR16","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jsbmb.2007.05.012","volume":"106","author":"SE Hankinson","year":"2007","unstructured":"Hankinson SE, Eliassen AH (2007) Endogenous estrogen, testosterone and progesterone levels in relation to breast cancer risk. J Steroid Biochem Mol Biol 106:24\u201330","journal-title":"J Steroid Biochem Mol Biol"},{"key":"1028_CR17","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1038\/nrclinonc.2011.110","volume":"8","author":"SA Narod","year":"2011","unstructured":"Narod SA (2011) Hormone replacement therapy and the risk of breast cancer. Nat Rev Clin Oncol 8:669\u2013676","journal-title":"Nat Rev Clin Oncol"},{"key":"1028_CR18","doi-asserted-by":"crossref","unstructured":"Collins R What makes UK Biobank special?. The Lancet. 379:1173\u20131174","DOI":"10.1016\/S0140-6736(12)60404-8"},{"key":"1028_CR19","unstructured":"Add UK Biobank. Repeat assessment data. 2013. Version 1.0. \n                    http:\/\/biobank.ctsu.ox.ac.uk\/~bbdatan\/Repeat_assessment_doc_v1.0.pdf\n                    \n                  . Accessed 1 Apr 2017"},{"key":"1028_CR20","doi-asserted-by":"publisher","first-page":"djw169","DOI":"10.1093\/jnci\/djw169","volume":"108","author":"RC Travis","year":"2016","unstructured":"Travis RC, Balkwill A, Fensom GK, Appleby PN, Reeves GK, Wang X-S, Roddam AW, Gathani T, Peto R, Green J, Key TJ, Beral V (2016). Night shift work and breast cancer incidence: three prospective studies and meta-analysis of published studies. JNCI 108:djw169\u2013djw169","journal-title":"JNCI"},{"key":"1028_CR21","volume-title":"The national diet and nutrition survey: adults aged 19 to 64 years. Summary report","author":"J Hoare","year":"2004","unstructured":"Hoare J, Henderson L, Bates C et al (2004) The national diet and nutrition survey: adults aged 19 to 64 years. Summary report. Office for National Statistics, Norwich"},{"key":"1028_CR22","doi-asserted-by":"publisher","first-page":"e6","DOI":"10.1017\/jns.2017.66","volume":"7","author":"KE Bradbury","year":"2018","unstructured":"Bradbury KE, Young HJ, Guo W, Key TJ (2018) Dietary assessment in UK Biobank: an evaluation of the performance of the touchscreen dietary questionnaire. J Nutr Sci 7:e6","journal-title":"J Nutr Sci"},{"key":"1028_CR23","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1007\/978-1-4757-3294-8","volume-title":"Modeling survival data: extending the Cox Model","author":"TM Therneau","year":"2000","unstructured":"Therneau TM, Grambsch PM (2000) Modeling survival data: extending the Cox Model. Springer, New York, pp\u00a0140\u2013152"},{"key":"1028_CR24","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1093\/oxfordjournals.aje.a116870","volume":"138","author":"AR Folsom","year":"1993","unstructured":"Folsom AR, McKenzie DR, Bisgard KM, Kushi LH, Sellers TA (1993) No association between caffeine intake and postmenopausal breast cancer incidence in the Iowa Women\u2019s Health Study. Am J Epidemiol 138:380\u2013383","journal-title":"Am J Epidemiol"},{"key":"1028_CR25","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1017\/S1368980011000371","volume":"14","author":"G Fagherazzi","year":"2011","unstructured":"Fagherazzi G, Touillaud MS, Boutron-Ruault MC, Clavel-Chapelon F, Romieu I (2011) No association between coffee, tea or caffeine consumption and breast cancer risk in a prospective cohort study. Public Health Nutr 14:1315\u20131320","journal-title":"Public Health Nutr"},{"key":"1028_CR26","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.1001\/archinte.168.18.2022","volume":"168","author":"K Ishitani","year":"2008","unstructured":"Ishitani K, Lin J, Manson JE, Buring JE, Zhang SM (2008) Caffeine consumption and the risk of breast cancer in a large prospective cohort of women. Arch Intern Med 168:2022\u20132031","journal-title":"Arch Intern Med"},{"key":"1028_CR27","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1038\/bjc.1994.258","volume":"70","author":"SJ Smith","year":"1994","unstructured":"Smith SJ, Deacon JM, Chilvers CE (1994) Alcohol, smoking, passive smoking and caffeine in relation to breast cancer risk in young women. UK National Case-Control Study Group. Br J Cancer 70:112\u2013119","journal-title":"Br J Cancer"},{"key":"1028_CR28","doi-asserted-by":"publisher","first-page":"2039","DOI":"10.1007\/s10552-009-9396-x","volume":"20","author":"SC Larsson","year":"2009","unstructured":"Larsson SC, Bergkvist L, Wolk A (2009) Coffee and black tea consumption and risk of breast cancer by estrogen and progesterone receptor status in a Swedish cohort. Cancer Causes Control 20:2039\u20132044","journal-title":"Cancer Causes Control"},{"key":"1028_CR29","doi-asserted-by":"publisher","first-page":"2071","DOI":"10.1002\/ijc.23336","volume":"122","author":"D Ganmaa","year":"2008","unstructured":"Ganmaa D, Willett WC, Li TY, Feskanich D, van Dam RM, Lopez-Garcia E, Hunter DJ, Holmes MD (2008) Coffee, tea, caffeine and risk of breast cancer: a 22-year follow-up. Int J Cancer 122:2071\u20132076","journal-title":"Int J Cancer"},{"key":"1028_CR30","doi-asserted-by":"publisher","first-page":"290 e1-9","DOI":"10.1016\/j.ajog.2008.10.019","volume":"200","author":"N Tang","year":"2009","unstructured":"Tang N, Zhou B, Wang B, Yu R (2009) Coffee consumption and risk of breast cancer: a metaanalysis. Am J Obstet Gynecol 200:290 e1-9","journal-title":"Am J Obstet Gynecol"},{"key":"1028_CR31","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1093\/ajcn\/69.2.243","volume":"69","author":"FB Hu","year":"1999","unstructured":"Hu FB, Rimm E, Smith-Warner SA, Feskanich D, Stampfer MJ, Ascherio A, Sampson L, Willett WC (1999) Reproducibility and validity of dietary patterns assessed with a food-frequency questionnaire. Am J Clin Nutr 69:243\u2013249","journal-title":"Am J Clin Nutr"},{"key":"1028_CR32","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1093\/oxfordjournals.aje.a114086","volume":"122","author":"WC Willett","year":"1985","unstructured":"Willett WC, Sampson L, Stampfer MJ, Rosner B, Bain C, Witschi J, Hennekens CH, Speizer FE (1985) Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol 122:51\u201365","journal-title":"Am J Epidemiol"},{"key":"1028_CR33","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-018-4667-4","author":"L Yaghjyan","year":"2018","unstructured":"Yaghjyan L, Colditz G, Rosner B, Gasparova A, Tamimi RM (2018). Associations of coffee consumption and caffeine intake with mammographic breast density. Breast Cancer Res Treat. \n                    https:\/\/doi.org\/10.1007\/s10549-018-4667-4","journal-title":"Breast Cancer Res Treat"}],"container-title":["Cancer Causes & Control"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10552-018-1028-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-018-1028-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-018-1028-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T20:00:05Z","timestamp":1555012805000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10552-018-1028-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,12]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["1028"],"URL":"https:\/\/doi.org\/10.1007\/s10552-018-1028-x","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"value":"0957-5243","type":"print"},{"value":"1573-7225","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,12]]},"assertion":[{"value":"22 November 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 April 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the University of Florida Institutional Review Board. UK Biobank was approved by the North West Multi-centre Research Ethics Committee (MREC), which covers the UK. All participants of UK Biobank provided written consent at recruitment.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Research involving human participants and\/or animals"}}]}}