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The aim of this study was to investigate the prevalence of HPV genotypes and their correlation to histological changes in women, 10\u00a0years after exclusion from the screening program, due to an eventual implementation of a catch-up program including all women aged 60\u201370.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>All women in \u00d6rebro County, born 1,946 (<jats:italic>n<\/jats:italic>\u2009=\u20091,968), were invited to a liquid-based cell sample with primary HPV screening. Samples were analyzed for hrHPV mRNA and positive samples were genotyped. hrHPV positive women were offered to do a conization.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Out of 809 participants, 31 (3.8%) were hrHPV positive, of these 22 did a conization. Histologically, 5\/22 (23%) had LSIL and 5\/22 (23%) had HSIL. Normal histology was found in 12\/22 (55%). The most prevalent genotypes were HPV 16, 33, 52, 56, and 68. Of the women with HSIL, one case of cervical cancer was confirmed in a recone biopsy after 4\u00a0months.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The study showed considerable prevalence of hrHPV and histologically confirmed LSIL\/HSIL. These data led to catch-up screening for women between 60 and 70\u00a0years when overlapping two screening strategies.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s10552-020-01278-0","type":"journal-article","created":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T06:13:42Z","timestamp":1582092822000},"page":"377-381","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of HPV and pathological changes among women 70\u00a0years of age, 10\u00a0years after exclusion from the Swedish cervical cancer screening program"],"prefix":"10.1007","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1458-1542","authenticated-orcid":false,"given":"Lovisa","family":"Bergengren","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mats G.","family":"Karlsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisela","family":"Helenius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,2,19]]},"reference":[{"issue":"6","key":"1278_CR1","doi-asserted-by":"publisher","first-page":"e0217108","DOI":"10.1371\/journal.pone.0217108","volume":"14","author":"L Bergengren","year":"2019","unstructured":"Bergengren L, Lillsunde-Larsson G, Helenius G, Karlsson MG (2019) HPV-based screening for cervical cancer among women 55\u201359 years of age. 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