{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:39:22Z","timestamp":1790246362874,"version":"4.1.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s10552-020-01353-6","type":"journal-article","created":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T16:03:53Z","timestamp":1602691433000},"page":"1051-1055","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Adiposity over the life course and prostate cancer: unraveling the complexities"],"prefix":"10.1007","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6123-0219","authenticated-orcid":false,"given":"Edward","family":"Giovannucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,14]]},"reference":[{"issue":"5","key":"1353_CR1","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1007\/s10552-020-01291-3","volume":"31","author":"S Harrison","year":"2020","unstructured":"Harrison S, Tilling K, Turner EL, Martin RM, Lennon R, Lane JA, Donovan JL, Hamdy FC, Neal DE, Ruud Bosch JLH, Jones HE (2020) Systematic review and meta-analysis of the associations between body mass index, prostate cancer, advanced prostate cancer, and prostate-specific antigen. Cancer Causes Control 31(5):431\u2013449","journal-title":"Cancer Causes Control"},{"key":"1353_CR2","unstructured":"World Cancer Research Fund\/American Institute for Cancer Research. Diet, nutrition, physical activity and prostate cancer. 2014 April 9, 2020]. https:\/\/www.wcrf.org\/sites\/default\/files\/Prostate-Cancer-2014-Report.pdf."},{"issue":"1","key":"1353_CR3","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.annonc.2019.09.007","volume":"31","author":"JM Genkinger","year":"2020","unstructured":"Genkinger JM, Wu K, Wang M, Albanes D, Black A, van den Brandt PA, Burke KA, Cook MB, Gapstur SM, Giles GG, Giovannucci E, Goodman GG, Hakansson N, Key TJ, Mannisto S, Marchand LL, Liao LM, MacInnis RJ, Neuhouser ML, Platz EA, Sawada N, Schenk JM, Stevens VL, Travis RC, Tsugane S, Visvanathan K, Wilkens LR, Wolk A, Smith-Warner SA (2020) Measures of body fatness and height in early and mid-to-late adulthood and prostate cancer: risk and mortality in the pooling project of prospective studies of diet and cancer. Ann Oncol 31(1):103\u2013114","journal-title":"Ann Oncol"},{"issue":"3","key":"1353_CR4","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1158\/1055-9965.EPI-08-0938","volume":"18","author":"RL Grubb 3rd","year":"2009","unstructured":"Grubb RL 3rd, Black A, Izmirlian G, Hickey TP, Pinsky PF, Mabie JE, Riley TL, Ragard LR, Prorok PC, Berg CD, Crawford ED, Church TR, Andriole GL Jr, PLCO Project Team (2009) Serum prostate-specific antigen hemodilution among obese men undergoing screening in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomark Prev 18(3):748\u2013751","journal-title":"Cancer Epidemiol Biomark Prev"},{"issue":"2","key":"1353_CR5","doi-asserted-by":"publisher","first-page":"djv088","DOI":"10.1093\/jnci\/djv088","volume":"107","author":"N Keum","year":"2015","unstructured":"Keum N, Greenwood DC, Lee DH, Kim R, Aune D, Ju W, Hu FB, Giovannucci EL (2015) Adult weight gain and adiposity-related cancers: a dose-response meta-analysis of prospective observational studies. J Natl Cancer Inst 107(2):djv088","journal-title":"J Natl Cancer Inst"},{"issue":"3","key":"1353_CR6","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1056\/NEJMoa030660","volume":"349","author":"IM Thompson","year":"2003","unstructured":"Thompson IM, Goodman PJ, Tangen CM, Lucia MS, Miller GJ, Ford LG, Lieber MM, Cespedes RD, Atkins JN, Lippman SM, Carlin SM, Ryan A, Szczepanek CM, Crowley JJ, Coltman CA Jr (2003) The influence of finasteride on the development of prostate cancer. N Engl J Med 349(3):215\u2013224","journal-title":"N Engl J Med"},{"issue":"4","key":"1353_CR7","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1002\/ijc.29842","volume":"138","author":"E Moller","year":"2016","unstructured":"Moller E, Wilson KM, Batista JL, Mucci LA, Balter K, Giovannucci E (2016) Body size across the life course and prostate cancer in the health professionals follow-up study. Int J Cancer 138(4):853\u2013865","journal-title":"Int J Cancer"},{"issue":"9","key":"1353_CR8","doi-asserted-by":"publisher","first-page":"2003","DOI":"10.1002\/ijc.30627","volume":"140","author":"B Rosner","year":"2017","unstructured":"Rosner B, Eliassen AH, Toriola AT, Chen WY, Hankinson SE, Willett WC, Berkey CS, Colditz GA (2017) Weight and weight changes in early adulthood and later breast cancer risk. Int J Cancer 140(9):2003\u20132014","journal-title":"Int J Cancer"},{"issue":"5","key":"1353_CR9","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1002\/ijc.30803","volume":"141","author":"BA Dickerman","year":"2017","unstructured":"Dickerman BA, Ahearn TU, Giovannucci E, Stampfer MJ, Nguyen PL, Mucci LA, Wilson KM (2017) Weight change, obesity and risk of prostate cancer progression among men with clinically localized prostate cancer. Int J Cancer 141(5):933\u2013944","journal-title":"Int J Cancer"},{"issue":"16","key":"1353_CR10","doi-asserted-by":"crossref","first-page":"2877","DOI":"10.1002\/cncr.32167","volume":"125","author":"BA Dickerman","year":"2019","unstructured":"Dickerman BA, Torfadottir JE, Valdimarsdottir UA, Giovannucci E, Wilson KM, Aspelund T, Tryggvadottir L, Sigurdardottir LG, Harris TB, Launer LJ, Gudnason V, Markt SC, Mucci LA (2019) Body fat distribution on computed tomography imaging and prostate cancer risk and mortality in AGES-Reykjavik study. Cancer 125(16):2877\u20132885","journal-title":"Cancer"},{"issue":"12","key":"1353_CR11","first-page":"1335","volume":"9","author":"AW Hsing","year":"2000","unstructured":"Hsing AW, Deng J, Sesterhenn IA, Mostofi FK, Stanczyk FZ, Benichou J, Xie T, Gao YT (2000) Body size and prostate cancer: a population-based case-control study in China. Cancer Epidemiol Biomark Prev 9(12):1335\u20131341","journal-title":"Cancer Epidemiol Biomark Prev"},{"issue":"1","key":"1353_CR12","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.juro.2018.01.069","volume":"200","author":"JS Lee","year":"2018","unstructured":"Lee JS, Lee HS, Ha JS, Han KS, Rha KH, Hong SJ, Chung BH, Koo KC (2018) Subcutaneous fat distribution is a prognostic biomarker for men with castration resistant prostate cancer. J Urol 200(1):114\u2013120","journal-title":"J Urol"},{"issue":"10","key":"1353_CR13","doi-asserted-by":"publisher","first-page":"2383","DOI":"10.1002\/ijc.29981","volume":"138","author":"M Song","year":"2016","unstructured":"Song M, Willett WC, Hu FB, Spiegelman D, Must A, Wu K, Chan AT, Giovannucci EL (2016) Trajectory of body shape across the lifespan and cancer risk. Int J Cancer 138(10):2383\u20132395","journal-title":"Int J Cancer"},{"issue":"2","key":"1353_CR14","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1093\/ije\/dyy219","volume":"48","author":"SP Kelly","year":"2019","unstructured":"Kelly SP, Lennon H, Sperrin M, Matthews C, Freedman NDA, Albanes D, Leitzmann MF, Renehan AG, Cook MB (2019) Body mass index trajectories across adulthood and smoking in relation to prostate cancer risks: the NIH-AARP diet and health study. Int J Epidemiol 48(2):464\u2013473","journal-title":"Int J Epidemiol"},{"key":"1353_CR15","doi-asserted-by":"publisher","first-page":"3241","DOI":"10.1002\/cam4.3241","volume":"9","author":"C Lavalette","year":"2020","unstructured":"Lavalette C, Duverger EC, Artaud F, Rebillard X, Lamy PJ, Tretarre B, Cenee SM, Menegaux F (2020) Body mass index trajectories and prostate cancer risk: results from the EPICAP study. Cancer Med 9:3241","journal-title":"Cancer Med"},{"issue":"3","key":"1353_CR16","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1093\/ije\/dyy201","volume":"48","author":"X Shu","year":"2019","unstructured":"Shu X, Wu L, Khankari NK, Shu XO, Wang TJ, Michailidou K, Bolla MK, Wang Q, Dennis J, Milne RL, Schmidt MK, Pharoah PDP, Andrulis IL, Hunter DJ, Simard J, Easton DF, Zheng W, Breast Cancer Association Consortium (2019) Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendalian randomization analysis. Int J Epidemiol 48(3):795\u2013806","journal-title":"Int J Epidemiol"},{"issue":"2","key":"1353_CR17","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1093\/ije\/dyz235","volume":"49","author":"Kazmi, N., P. Haycock, K. Tsilidis, B.M. Lynch, T. Truong, PRACTICAL Consortium, CRUCK, BPC3, CAPS, PEGASUS, R.M. Martin and S.J. Lewis","year":"2020","unstructured":"Kazmi, N., P. Haycock, K. Tsilidis, B.M. Lynch, T. Truong, PRACTICAL Consortium, CRUCK, BPC3, CAPS, PEGASUS, R.M. Martin and S.J. Lewis (2020) Appraising causal relationships of dietary, nutritional and physical-activity exposures with overall and aggressive prostate cancer: two-sample Mendelian-randomization study based on 79148 prostate-cancer cases and 61106 controls. Int J Epidemiol 49(2):587\u2013596","journal-title":"Int J Epidemiol"},{"issue":"5","key":"1353_CR18","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.eururo.2018.07.024","volume":"74","author":"EL Watts","year":"2018","unstructured":"Watts EL, Appleby PN, Perez-Cornago A, Bueno-de-Mesquita HB, Chan JM, Chen C, Cohn BA, Cook MB, Flicker L, Freedman ND, Giles GG, Giovannucci E, Gislefoss RE, Hankey GJ, Kaaks R, Knekt P, Kolonel LN, Kubo T, Marchand LL, Luben RN, Luostarinen T, Mannisto S, Metter EJ, Mikami K, Milne RL, Ozasa K, Platz EA, Quiros JR, Rissanen H, Sawada N, Stampfer M, Stanczyk FZ, Stattin P, Tamakoshi A, Tangen CM, Thompson IM, Tsilidis KK, Tsugane S, Ursin G, Vatten L, Weiss NS, Yeap BB, Allen NE, Key TJ, Travis RC (2018) Low free testosterone and prostate cancer risk: a collaborative analysis of 20 prospective studies. Eur Urol 74(5):585\u2013594","journal-title":"Eur Urol"},{"issue":"1","key":"1353_CR19","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/0026-0495(91)90199-7","volume":"40","author":"R Pasquali","year":"1991","unstructured":"Pasquali R, Casimirri F, Cantobelli S, Melchionda N, Morselli Labate AM, Fabbri R, Capelli M, Bortoluzzi L (1991) Effect of obesity and body fat distribution on sex hormones and insulin in men. Metabolism 40(1):101\u2013104","journal-title":"Metabolism"},{"issue":"10","key":"1353_CR20","doi-asserted-by":"publisher","first-page":"1266","DOI":"10.3390\/ijerph14101266","volume":"14","author":"W Li","year":"2017","unstructured":"Li W, Liu Q, Deng X, Chen Y, Liu SS (2017) Association between obesity and puberty timing: a systematic review and meta-analysis. Int J Environ Res Public Health 14(10):1266","journal-title":"Int J Environ Res Public Health"},{"issue":"2","key":"1353_CR21","doi-asserted-by":"publisher","first-page":"e20150164","DOI":"10.1542\/peds.2015-0164","volume":"137","author":"JM Lee","year":"2016","unstructured":"Lee JM, Wasserman R, Kaciroti N, Gebremariam A, Steffes J, Dowshen S, Harris D, Serwint J, Abney D, Smitherman L, Reiter E, Herman-Giddens ME (2016) Timing of puberty in overweight versus obese boys. Pediatrics 137(2):e20150164","journal-title":"Pediatrics"},{"issue":"3","key":"1353_CR22","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1111\/acel.12068","volume":"12","author":"L Fontana","year":"2013","unstructured":"Fontana L, Addante F, Copetti M, Paroni G, Fontana A, Sancario D, Pellegrini F, Ferrucci L, Pilotto A (2013) Identification of a metabolic signature for multidimensional impairment and mortality risk in hospitalized older patients. Aging Cell 12(3):459\u2013466","journal-title":"Aging Cell"},{"issue":"8","key":"1353_CR23","doi-asserted-by":"publisher","first-page":"2288","DOI":"10.1158\/0008-5472.CAN-15-1551","volume":"76","author":"RC Travis","year":"2016","unstructured":"Travis RC, Appleby PN, Martin RM, Holly JMP, Albanes D, Black A, Bueno-de-Mesquita HBA, Chan JM, Chen C, Chirlaque MD, Cook MB, Deschasaux M, Donovan JL, Ferrucci L, Galan P, Giles GG, Giovannucci EL, Gunter MJ, Habel LA, Hamdy FC, Helzlsouer KJ, Hercberg S, Hoover RN, Janssen JAMJL, Kaaks R, Kubo T, Marchand LL, Metter EJ, Mikami K, Morris JK, Neal DE, Neuhouser ML, Ozasa K, Palli D, Platz EA, Pollak M, Price AJ, Roobol MJ, Schaefer C, Schenk JM, Severi G, Stampfer MJ, Stattin P, Tamakoshi A, Tangen CM, Touvier M, Wald NJ, Weiss NS, Ziegler RG, Key TJ, Allen NE (2016) A meta-analysis of individual participant data reveals an association between circulating levels of IGF-I and prostate cancer risk. Cancer Res 76(8):2288\u20132300","journal-title":"Cancer Res"},{"issue":"9","key":"1353_CR24","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1002\/pros.21503","volume":"72","author":"C Ziegler-Johnson","year":"2012","unstructured":"Ziegler-Johnson C, Weber A, Spangler E, Panossian S, Rebbeck TR, Malkowicz SB (2012) Relationship of obesity, androgen receptor genotypes and biochemical failure after radical prostatectomy. Prostate 72(9):984\u2013990","journal-title":"Prostate"},{"issue":"24","key":"1353_CR25","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1093\/jnci\/djt332","volume":"105","author":"A Pettersson","year":"2013","unstructured":"Pettersson A, Lis RT, Meisner A, Flavin R, Stack EC, Fiorentino M, Finn S, Graff RE, Penney KL, Rider JR, Nuttell EJ, Martin NE, Sesso HD, Pollak M, Stampfer MJ, Kantoff PW, Giovannucci EL, Loda M, Mucci LA (2013) Modification of the association between obesity and lethal prostate cancer by TMPRSS2:ERG. J Natl Cancer Inst 105(24):1881\u20131890","journal-title":"J Natl Cancer Inst"}],"container-title":["Cancer Causes &amp; Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-020-01353-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10552-020-01353-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-020-01353-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T19:27:23Z","timestamp":1696879643000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10552-020-01353-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,14]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["1353"],"URL":"https:\/\/doi.org\/10.1007\/s10552-020-01353-6","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"value":"0957-5243","type":"print"},{"value":"1573-7225","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,14]]},"assertion":[{"value":"15 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}