{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T05:16:10Z","timestamp":1785820570140,"version":"3.56.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T00:00:00Z","timestamp":1618876800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T00:00:00Z","timestamp":1618876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100011541","name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011541","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s10552-021-01432-2","type":"journal-article","created":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T12:02:34Z","timestamp":1618920154000},"page":"803-813","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Risk factors for contralateral breast cancer in postmenopausal breast cancer survivors in the NIH-AARP Diet and Health Study"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2007-2840","authenticated-orcid":false,"given":"Cody","family":"Ramin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maeve","family":"Mullooly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara J.","family":"Schonfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pragati G.","family":"Advani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Bodelon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gretchen L.","family":"Gierach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy Berrington","family":"de Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,20]]},"reference":[{"key":"1432_CR1","volume-title":"Cancer treatment & survivorship facts & figures 2019\u20132021","author":"American Cancer Society","year":"2019","unstructured":"American Cancer Society (2019) Cancer treatment & survivorship facts & figures 2019\u20132021. American Cancer Society, Atlanta"},{"issue":"10","key":"1432_CR2","first-page":"855","volume":"8","author":"Y Chen","year":"1999","unstructured":"Chen Y, Thompson W, Semenciw R et al (1999) Epidemiology of contralateral breast cancer. Cancer Epidemiol Biomark Prev 8(10):855\u2013861","journal-title":"Cancer Epidemiol Biomark Prev"},{"key":"1432_CR3","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s13058-021-01400-3","volume":"23","author":"C Ramin","year":"2021","unstructured":"Ramin C, Withrow DR, Davis Lynn BC et al (2021) Risk of contralateral breast cancer according to first breast cancer characteristics among women in the USA, 1992\u20132016. Breast Cancer Res 23:24","journal-title":"Breast Cancer Res"},{"key":"1432_CR4","unstructured":"Curtis RE, Freeman DM, Ron E et al (Eds) (2006) New malignancies among cancer survivors: SEER Cancer Registries, 1973\u20132000. Volume Publication Number 05\u20135302 National Cancer Institute, NIH, Bethesda, MD"},{"issue":"15","key":"1432_CR5","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1200\/JCO.2017.77.3424","volume":"36","author":"AS Reiner","year":"2018","unstructured":"Reiner AS, Sisti J, John EM et al (2018) Breast cancer family history and contralateral breast cancer risk in young women: an update from the Women\u2019s Environmental Cancer and Radiation Epidemiology study. J Clin Oncol 36(15):1513\u20131520","journal-title":"J Clin Oncol"},{"issue":"5","key":"1432_CR6","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1002\/ijc.30791","volume":"141","author":"JA Knight","year":"2017","unstructured":"Knight JA, Fan J, Malone KE et al (2017) Alcohol consumption and cigarette smoking in combination: a predictor of contralateral breast cancer risk in the WECARE study. Int J Cancer 141(5):916\u2013924","journal-title":"Int J Cancer"},{"issue":"11","key":"1432_CR7","doi-asserted-by":"publisher","first-page":"3282","DOI":"10.1002\/cam4.890","volume":"5","author":"JD Brooks","year":"2016","unstructured":"Brooks JD, John EM, Mellemkj\u00e6r L et al (2016) Body mass index, weight change, and risk of second primary breast cancer in the WECARE study: influence of estrogen receptor status of the first breast cancer. Cancer Med 5(11):3282\u20133291","journal-title":"Cancer Med"},{"issue":"1","key":"1432_CR8","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1186\/s40064-015-1642-y","volume":"4","author":"JS Sisti","year":"2015","unstructured":"Sisti JS, Bernstein JL, Lynch CF et al (2015) Reproductive factors, tumor estrogen receptor status and contralateral breast cancer risk: results from the WECARE study. Springerplus 4(1):825","journal-title":"Springerplus"},{"issue":"4","key":"1432_CR9","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1016\/j.ijrobp.2012.01.047","volume":"84","author":"JD Brooks","year":"2012","unstructured":"Brooks JD, Boice JD, Stovall M et al (2012) Reproductive status at first diagnosis influences risk of radiation-induced second primary contralateral breast cancer in the WECARE study. Int J Radiat Oncol Biol Phys 84(4):917\u2013924","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1432_CR10","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1007\/s10549-011-1743-4","volume":"131","author":"JD Brooks","year":"2012","unstructured":"Brooks JD, John EM, Mellemkj\u00e6r L et al (2012) Body mass index and risk of second primary breast cancer: the WECARE Study. Breast Cancer Res Treat 131:571\u2013580","journal-title":"Breast Cancer Res Treat"},{"issue":"6","key":"1432_CR11","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1007\/s10552-010-9510-0","volume":"21","author":"JN Poynter","year":"2010","unstructured":"Poynter JN, Langholz B, Largent J et al (2010) Reproductive factors and risk of contralateral breast cancer by BRCA1 and BRCA2 mutation status: results from the WECARE study. Cancer Causes Control 21(6):839\u2013846","journal-title":"Cancer Causes Control"},{"issue":"8","key":"1432_CR12","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1093\/aje\/kwn422","volume":"169","author":"JA Knight","year":"2009","unstructured":"Knight JA, Bernstein L, Largent J et al (2009) Alcohol intake and cigarette smoking and risk of a contralateral breast cancer: the Women\u2019s Environmental Cancer and Radiation Epidemiology Study. Am J Epidemiol 169(8):962\u2013968","journal-title":"Am J Epidemiol"},{"issue":"5","key":"1432_CR13","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1158\/1055-9965.EPI-06-1003","volume":"16","author":"JA Largent","year":"2007","unstructured":"Largent JA, Capanu M, Bernstein L et al (2007) Reproductive history and risk of second primary breast cancer: the WECARE Study. Cancer Epidemiol Biomark Prev 16(5):906\u2013911","journal-title":"Cancer Epidemiol Biomark Prev"},{"issue":"3","key":"1432_CR14","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/sj.bjc.6601042","volume":"89","author":"CI Li","year":"2003","unstructured":"Li CI, Malone KE, Porter PL et al (2003) Epidemiologic and molecular risk factors for contralateral breast cancer among young women. Br J Cancer 89(3):513\u2013518","journal-title":"Br J Cancer"},{"issue":"8","key":"1432_CR15","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1093\/oxfordjournals.aje.a116565","volume":"136","author":"JL Bernstein","year":"1992","unstructured":"Bernstein JL, Thompson WD, Risch N et al (1992) Risk factors predicting the incidence of second primary breast cancer among women diagnosed with a first primary breast cancer. Am J Epidemiol 136(8):925\u2013936","journal-title":"Am J Epidemiol"},{"issue":"3","key":"1432_CR16","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1007\/s10549-010-1153-z","volume":"126","author":"B Majed","year":"2011","unstructured":"Majed B, Dozol A, Ribassin-Majed L et al (2011) Increased risk of contralateral breast cancers among overweight and obese women: a time-dependent association. Breast Cancer Res Treat 126(3):729\u2013738","journal-title":"Breast Cancer Res Treat"},{"issue":"32","key":"1432_CR17","doi-asserted-by":"publisher","first-page":"5312","DOI":"10.1200\/JCO.2009.23.1597","volume":"27","author":"CI Li","year":"2009","unstructured":"Li CI, Daling JR, Porter PL et al (2009) Relationship between potentially modifiable lifestyle factors and risk of second primary contralateral breast cancer among women diagnosed with estrogen receptor\u2013positive invasive breast cancer. J Clin Oncol 27(32):5312\u20135318","journal-title":"J Clin Oncol"},{"issue":"6","key":"1432_CR18","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1002\/1097-0215(20001215)88:6<998::AID-IJC25>3.0.CO;2-0","volume":"88","author":"P Vaittinen","year":"2000","unstructured":"Vaittinen P, Hemminki K (2000) Risk factors and age-incidence relationships for contralateral breast cancer. Int J Cancer 88(6):998\u20131002","journal-title":"Int J Cancer"},{"issue":"3","key":"1432_CR19","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1007\/BF00052945","volume":"7","author":"LS Cook","year":"1996","unstructured":"Cook LS, White E, Schwartz SM et al (1996) A population-based study of contralateral breast cancer following a first primary breast cancer (Washington, United States). Cancer Causes Control 7(3):382\u2013390","journal-title":"Cancer Causes Control"},{"issue":"2","key":"1432_CR20","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1093\/oxfordjournals.aje.a114971","volume":"128","author":"PL Horn","year":"1988","unstructured":"Horn PL, Thompson WD (1988) Risk of contralateral breast cancer: associations with factors related to initial breast cancer. Am J Epidemiol 128(2):309\u2013323","journal-title":"Am J Epidemiol"},{"issue":"1","key":"1432_CR21","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1093\/jnci\/djm267","volume":"100","author":"L Bertelsen","year":"2008","unstructured":"Bertelsen L, Bernstein L, Olsen JH et al (2008) Effect of systemic adjuvant treatment on risk for contralateral breast cancer in the Women\u2019s Environment, Cancer and Radiation Epidemiology study. J Natl Cancer Inst 100(1):32\u201340","journal-title":"J Natl Cancer Inst"},{"issue":"12","key":"1432_CR22","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1056\/NEJM199203193261201","volume":"326","author":"JD Boice","year":"1992","unstructured":"Boice JD, Harvey EB, Blettner M et al (1992) Cancer in the contralateral breast after radiotherapy for breast cancer. N Engl J Med 326(12):781\u2013785","journal-title":"N Engl J Med"},{"issue":"1","key":"1432_CR23","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/s10549-010-1137-z","volume":"127","author":"C Bouchardy","year":"2011","unstructured":"Bouchardy C, Benhamou S, Fioretta G et al (2011) Risk of second breast cancer according to estrogen receptor status and family history. Breast Cancer Res Treat 127(1):233\u2013241","journal-title":"Breast Cancer Res Treat"},{"issue":"15","key":"1432_CR24","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1093\/jnci\/djp181","volume":"101","author":"AW Kurian","year":"2009","unstructured":"Kurian AW, McClure LA, John EM et al (2009) Second primary breast cancer occurrence according to hormone receptor status. J Natl Cancer Inst 101(15):1058\u20131065","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"1432_CR25","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/s13058-016-0726-0","volume":"18","author":"R Langballe","year":"2016","unstructured":"Langballe R, Mellemkj\u00e6r L, Malone KE et al (2016) Systemic therapy for breast cancer and risk of subsequent contralateral breast cancer in the WECARE Study. Breast Cancer Res 18(1):65","journal-title":"Breast Cancer Res"},{"issue":"1","key":"1432_CR26","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s13058-017-0874-x","volume":"19","author":"AS Reiner","year":"2017","unstructured":"Reiner AS, Lynch CF, Sisti JS et al (2017) Hormone receptor status of a first primary breast cancer predicts contralateral breast cancer risk in the WECARE study population. Breast Cancer Res 19(1):83","journal-title":"Breast Cancer Res"},{"issue":"3","key":"1432_CR27","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1007\/s10549-012-2183-5","volume":"135","author":"BS Saltzman","year":"2012","unstructured":"Saltzman BS, Malone KE, McDougall JA et al (2012) Estrogen receptor, progesterone receptor, and HER2-neu expression in first primary breast cancers and risk of second primary contralateral breast cancer. Breast Cancer Res Treat 135(3):849\u2013855","journal-title":"Breast Cancer Res Treat"},{"issue":"10","key":"1432_CR28","doi-asserted-by":"publisher","first-page":"e46535","DOI":"10.1371\/journal.pone.0046535","volume":"7","author":"MEC Sandberg","year":"2012","unstructured":"Sandberg MEC, Hall P, Hartman M et al (2012) Estrogen receptor status in relation to risk of contralateral breast cancer\u2013a population-based cohort study. PLoS ONE 7(10):e46535","journal-title":"PLoS ONE"},{"issue":"12","key":"1432_CR29","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1093\/aje\/154.12.1119","volume":"154","author":"A Schatzkin","year":"2001","unstructured":"Schatzkin A, Subar AF, Thompson FE et al (2001) Design and serendipity in establishing a large cohort with wide dietary intake distributions: the National Institutes of Health-American Association of Retired Persons Diet and Health Study. Am J Epidemiol 154(12):1119\u20131125","journal-title":"Am J Epidemiol"},{"key":"1432_CR30","first-page":"70","volume":"32","author":"D Michaud","year":"2005","unstructured":"Michaud D, Midthune D, Hermansen S et al (2005) Comparison of cancer registry case ascertainment with SEER estimates and self-reporting in a subset of the NIH-AARP Diet and Health Study. J Registry Manage 32:70\u201375","journal-title":"J Registry Manage"},{"key":"1432_CR31","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1097\/SLA.0000000000001698","volume":"265","author":"SM Wong","year":"2017","unstructured":"Wong SM, Freedman RA, Sagara Y et al (2017) Growing use of contralateral prophylactic mastectomy despite no improvement in long-term survival for invasive breast cancer. Ann Surg 265:581\u2013589","journal-title":"Ann Surg"},{"key":"1432_CR32","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","volume":"94","author":"JP Fine","year":"1999","unstructured":"Fine JP, Gray RJ (1999) A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 94:496\u2013509","journal-title":"J Am Stat Assoc"},{"issue":"5","key":"1432_CR33","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1007\/s10552-020-01284-2","volume":"31","author":"DKM Akdeniz","year":"2020","unstructured":"Akdeniz DKM, Smith CZA, Koppert LB et al (2020) The impact of lifestyle and reproductive factors on the risk of a second new primary cancer in the contralateral breast: a systematic review and meta-analysis. Cancer Causes Control 31(5):403\u2013416","journal-title":"Cancer Causes Control"},{"issue":"9793","key":"1432_CR34","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1016\/S0140-6736(11)60993-8","volume":"378","author":"Early Breast Cancer Trialists' Collaborative Group","year":"2011","unstructured":"Early Breast Cancer Trialists\u2019 Collaborative Group (2011) Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. Lancet 378(9793):771\u2013784","journal-title":"Lancet"},{"issue":"10001","key":"1432_CR35","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1016\/S0140-6736(15)61074-1","volume":"386","author":"Early Breast Cancer Trialists' Collaborative Group","year":"2015","unstructured":"Early Breast Cancer Trialists\u2019 Collaborative Group (2015) Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials. Lancet 386(10001):1341\u20131352","journal-title":"Lancet"},{"issue":"2","key":"1432_CR36","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1001\/jamaoncol.2016.3340","volume":"3","author":"GL Gierach","year":"2017","unstructured":"Gierach GL, Curtis RE, Pfeiffer RM et al (2017) Association of adjuvant tamoxifen and aromatase inhibitor therapy with contralateral breast cancer risk among US women with breast cancer in a general community setting. JAMA Oncol 3(2):186\u2013193","journal-title":"JAMA Oncol"},{"issue":"7","key":"1432_CR37","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1093\/jnci\/djz010","volume":"111","author":"I Kramer","year":"2019","unstructured":"Kramer I, Schaapveld M, Oldenburg HSA et al (2019) The influence of adjuvant systemic regimens on contralateral breast cancer risk and receptor subtype. J Natl Cancer Inst 111(7):709\u2013718","journal-title":"J Natl Cancer Inst"},{"issue":"8","key":"1432_CR38","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1093\/oxfordjournals.aje.a116566","volume":"136","author":"JL Bernstein","year":"1992","unstructured":"Bernstein JL, Thompson WD, Risch N et al (1992) The genetic epidemiology of second primary breast cancer. Am J Epidemiol 136(8):937\u2013948","journal-title":"Am J Epidemiol"},{"issue":"4","key":"1432_CR39","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1200\/JCO.2012.43.2013","volume":"31","author":"AS Reiner","year":"2013","unstructured":"Reiner AS, John EM, Brooks JD et al (2013) Risk of asynchronous contralateral breast cancer in noncarriers of BRCA1 and BRCA2 mutations with a family history of breast cancer: A report from the Women\u2019s Environmental Cancer and Radiation Epidemiology study. J Clin Oncol 31(4):433\u2013439","journal-title":"J Clin Oncol"}],"container-title":["Cancer Causes &amp; Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-021-01432-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10552-021-01432-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-021-01432-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T20:07:16Z","timestamp":1628885236000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10552-021-01432-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,20]]},"references-count":39,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["1432"],"URL":"https:\/\/doi.org\/10.1007\/s10552-021-01432-2","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"value":"0957-5243","type":"print"},{"value":"1573-7225","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,20]]},"assertion":[{"value":"30 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 April 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The NIH-AARP Diet and Health Study (Protocol Number: OH95CN025) was approved by the Special Studies Institutional Review Board (SSIRB) of the US National Cancer Institute. This study was conducted in accordance with the ethical standards of the institutional review board and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All participants provided informed consent by completing and returning the self-administered baseline questionnaire.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}