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Biopsy or surgery confirmed BC cases were identified through the state population-based cancer registry with information on patients\u2019 characteristics and vital status. Physician-diagnosed T2DM was confirmed based on primary health care clinical history. Cox regression analyses were used to estimate adjusted hazard ratios (aHR) and 95% confidence intervals (CI) for all-cause death. Analyses were adjusted for age, hospital size, several clinical characteristics (including BC stage and histology, among others) and treatment modalities.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among the 4,493 BC women, 388 (8.6%) had coexisting T2DM. Overall, 1,299 (28.9%) BC women died during the completion of the follow-up and 785 (17.5%) did so during the first five years after BC diagnosis, resulting in a five-year survival rate of 82.5%. The death rate was higher in women with T2DM (43.8% died during whole period and 26.0% during the first five years) when compared with women without T2DM (27.5% and 16.7%, respectively). Accordingly, all-cause mortality was higher in women with T2DM (aHR: 1.22; 95% CI 1.03\u20131.44), especially if T2DM was diagnosed before BC (aHR:1.24; 95% CI 1.03\u20131.50) and in women with BC diagnosed before 50\u00a0years (aHR: 2.38; 95% CI 1.04\u20135.48).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>T2DM was associated with higher all-cause mortality among Spanish women with BC, particularly when the T2DM diagnosis was prior to the BC.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10552-021-01526-x","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T19:04:50Z","timestamp":1638385490000},"page":"271-278","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Type 2 Diabetes and all-cause mortality among Spanish women with breast cancer"],"prefix":"10.1007","volume":"33","author":[{"given":"L.","family":"Fern\u00e1ndez-Arce","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Robles-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5718-0570","authenticated-orcid":false,"given":"A.","family":"Fern\u00e1ndez-Feito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Llaneza-Folgueras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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