{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T01:11:58Z","timestamp":1775869918114,"version":"3.50.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T00:00:00Z","timestamp":1738108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T00:00:00Z","timestamp":1738108800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R03 HD102403"],"award-info":[{"award-number":["R03 HD102403"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1007\/s10552-025-01962-z","type":"journal-article","created":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T02:26:57Z","timestamp":1738117617000},"page":"617-624","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Infertility and Risk of Ovarian Cancer in the Women\u2019s Health Initiative"],"prefix":"10.1007","volume":"36","author":[{"given":"Holly R.","family":"Harris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly","family":"Lind","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sable","family":"Fest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia A.","family":"Thomson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazmus","family":"Saquib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aladdin H.","family":"Shadyab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter F.","family":"Schnatz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rogelio","family":"Robles-Morales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihong","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard D.","family":"Strickler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise J.","family":"Roe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie V.","family":"Farland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,29]]},"reference":[{"key":"1962_CR1","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.1093\/humrep\/des466","volume":"28","author":"MA Merritt","year":"2013","unstructured":"Merritt MA, De Pari M, Vitonis AF, Titus LJ, Cramer DW, Terry KL (2013) Reproductive characteristics in relation to ovarian cancer risk by histologic pathways. Hum Reprod 28:1406\u20131417","journal-title":"Hum Reprod"},{"key":"1962_CR2","doi-asserted-by":"publisher","first-page":"9","DOI":"10.20892\/j.issn.2095-3941.2016.0084","volume":"14","author":"BM Reid","year":"2017","unstructured":"Reid BM, Permuth JB, Sellers TA (2017) Epidemiology of ovarian cancer: a review. Cancer Biol Med 14:9\u201332","journal-title":"Cancer Biol Med"},{"key":"1962_CR3","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1097\/01.AOG.0000128139.92313.74","volume":"103","author":"LA Brinton","year":"2004","unstructured":"Brinton LA, Lamb EJ, Moghissi KS et al (2004) Ovarian cancer risk after the use of ovulation-stimulating drugs. Obstet Gynecol 103:1194\u20131203","journal-title":"Obstet Gynecol"},{"key":"1962_CR4","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/s10815-016-0836-8","volume":"34","author":"B Hanson","year":"2017","unstructured":"Hanson B, Johnstone E, Dorais J, Silver B, Peterson CM, Hotaling J (2017) Female infertility, infertility-associated diagnoses, and comorbidities: a review. J Assist Reprod Genet 34:167\u2013177","journal-title":"J Assist Reprod Genet"},{"key":"1962_CR5","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1093\/humrep\/deq307","volume":"26","author":"B Kallen","year":"2011","unstructured":"Kallen B, Finnstrom O, Lindam A, Nilsson E, Nygren KG, Olausson PO (2011) Malignancies among women who gave birth after in vitro fertilization. Hum Reprod 26:253\u2013258","journal-title":"Hum Reprod"},{"key":"1962_CR6","doi-asserted-by":"publisher","first-page":"1218","DOI":"10.1016\/j.fertnstert.2015.07.1135","volume":"104","author":"B Luke","year":"2015","unstructured":"Luke B, Brown MB, Spector LG et al (2015) Cancer in women after assisted reproductive technology. Fertil Steril 104:1218\u20131226","journal-title":"Fertil Steril"},{"key":"1962_CR7","doi-asserted-by":"publisher","first-page":"1952","DOI":"10.1093\/humrep\/dev124","volume":"30","author":"MM Reigstad","year":"2015","unstructured":"Reigstad MM, Larsen IK, Myklebust TA et al (2015) Cancer risk among parous women following assisted reproductive technology. Hum Reprod 30:1952\u20131963","journal-title":"Hum Reprod"},{"key":"1962_CR8","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1158\/1055-9965.EPI-16-0809","volume":"26","author":"MM Reigstad","year":"2017","unstructured":"Reigstad MM, Storeng R, Myklebust TA et al (2017) Cancer risk in women treated with fertility drugs according to parity status-a registry-based cohort study. Cancer Epidemiol Biomarkers Prev 26:953\u2013962","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"1962_CR9","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1016\/S0140-6736(99)05203-4","volume":"354","author":"A Venn","year":"1999","unstructured":"Venn A, Watson L, Bruinsma F, Giles G, Healy D (1999) Risk of cancer after use of fertility drugs with in-vitro fertilisation. Lancet 354:1586\u20131590","journal-title":"Lancet"},{"key":"1962_CR10","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1158\/1055-9965.EPI-17-0655","volume":"27","author":"HR Harris","year":"2018","unstructured":"Harris HR, Babic A, Webb PM et al (2018) Polycystic ovary syndrome, oligomenorrhea, and risk of ovarian cancer histotypes: evidence from the ovarian cancer association consortium. Cancer Epidemiol Biomarkers Prev 27:174\u2013182","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"1962_CR11","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s40738-016-0029-2","volume":"2","author":"HR Harris","year":"2016","unstructured":"Harris HR, Terry KL (2016) Polycystic ovary syndrome and risk of endometrial, ovarian, and breast cancer: a systematic review. Fertil Res Pract 2:14","journal-title":"Fertil Res Pract"},{"key":"1962_CR12","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmv013","author":"M Kvaskoff","year":"2015","unstructured":"Kvaskoff M, Mu F, Terry KL et al (2015) Endometriosis: a high-risk population for major chronic diseases? Human Reprod Update. https:\/\/doi.org\/10.1093\/humupd\/dmv013","journal-title":"Human Reprod Update"},{"key":"1962_CR13","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1093\/aje\/155.3.217","volume":"155","author":"RB Ness","year":"2002","unstructured":"Ness RB, Cramer DW, Goodman MT et al (2002) Infertility, fertility drugs, and ovarian cancer: a pooled analysis of case-control studies. Am J Epidemiol 155:217\u2013224","journal-title":"Am J Epidemiol"},{"key":"1962_CR14","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1007\/s10552-017-0856-4","volume":"28","author":"EM Poole","year":"2017","unstructured":"Poole EM, Lin WT, Kvaskoff M, De Vivo I, Terry KL, Missmer SA (2017) Endometriosis and risk of ovarian and endometrial cancers in a large prospective cohort of U.S. nurses. Cancer Causes Control\u202f: CCC 28:437\u2013445","journal-title":"Cancer Causes Control : CCC"},{"key":"1962_CR15","first-page":"447","volume":"4","author":"HA Risch","year":"1995","unstructured":"Risch HA, Howe GR (1995) Pelvic inflammatory disease and the risk of epithelial ovarian cancer. Cancer Epidemiol Biomarkers Prev 4:447\u2013451","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"1962_CR16","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/S1470-2045(11)70404-1","volume":"13","author":"CL Pearce","year":"2012","unstructured":"Pearce CL, Templeman C, Rossing MA et al (2012) Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. Lancet Oncol 13:385\u2013394","journal-title":"Lancet Oncol"},{"key":"1962_CR17","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1055\/s-0032-1307421","volume":"30","author":"LA Brinton","year":"2012","unstructured":"Brinton LA, Sahasrabuddhe VV, Scoccia B (2012) Fertility drugs and the risk of breast and gynecologic cancers. Semin Reprod Med 30:131\u2013145","journal-title":"Semin Reprod Med"},{"key":"1962_CR18","unstructured":"National Academies of Sciences E, and Medicine. (2016) Ovarian cancers: Evolving paradigms in research and care Washington, DC: The National Academies Press"},{"key":"1962_CR19","volume-title":"Cancer Facts & Figures 2024","author":"American Cancer Society I","year":"2024","unstructured":"American Cancer Society I (2024) Cancer Facts & Figures 2024. American Cancer Society, Atlanta"},{"key":"1962_CR20","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1093\/humupd\/dmi016","volume":"11","author":"J Cohen","year":"2005","unstructured":"Cohen J, Trounson A, Dawson K et al (2005) The early days of IVF outside the UK. Hum Reprod Update 11:439\u2013460","journal-title":"Hum Reprod Update"},{"key":"1962_CR21","doi-asserted-by":"crossref","unstructured":"(1998) Design of the Women's Health Initiative clinical trial and observational study. The Women\u2019s health initiative study group. Controlled Clinical Trials. 19: 61\u2013109.","DOI":"10.1016\/S0197-2456(97)00078-0"},{"key":"1962_CR22","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1001\/jama.2013.278040","volume":"310","author":"JE Manson","year":"2013","unstructured":"Manson JE, Chlebowski RT, Stefanick ML et al (2013) Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the women\u2019s health initiative randomized trials. JAMA 310:1353\u20131368","journal-title":"JAMA"},{"key":"1962_CR23","doi-asserted-by":"publisher","first-page":"S18","DOI":"10.1016\/S1047-2797(03)00042-5","volume":"13","author":"J Hays","year":"2003","unstructured":"Hays J, Hunt JR, Hubbell FA et al (2003) The women\u2019s health Initiative recruitment methods and results. Ann Epidemiol 13:S18-77","journal-title":"Ann Epidemiol"},{"key":"1962_CR24","doi-asserted-by":"publisher","first-page":"e52","DOI":"10.1097\/GRH.0000000000000052","volume":"6","author":"WH Organization","year":"2021","unstructured":"Organization WH (2021) WHO fact sheet on infertility. Global Reprod Health 6:e52","journal-title":"Global Reprod Health"},{"key":"1962_CR25","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1093\/humrep\/dex234","volume":"32","author":"F Zegers-Hochschild","year":"2017","unstructured":"Zegers-Hochschild F, Adamson GD, Dyer S et al (2017) The international glossary on infertility and fertility care, 2017. Hum Reprod 32:1786\u20131801","journal-title":"Hum Reprod"},{"key":"1962_CR26","doi-asserted-by":"publisher","first-page":"1594","DOI":"10.1016\/j.jacc.2022.02.020","volume":"79","author":"ES Lau","year":"2022","unstructured":"Lau ES, Wang D, Roberts M et al (2022) Infertility and risk of heart failure in the women\u2019s health initiative. J Am Coll Cardiol 79:1594\u20131603","journal-title":"J Am Coll Cardiol"},{"key":"1962_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2022.09.224","author":"G Murugappan","year":"2022","unstructured":"Murugappan G, Leonard SA, Farland LV et al (2022) Association of infertility with atherosclerotic cardiovascular disease among postmenopausal participants in the women\u2019s health initiative. Fertil Steril. https:\/\/doi.org\/10.1016\/j.fertnstert.2022.09.224","journal-title":"Fertil Steril"},{"key":"1962_CR28","unstructured":"Cancer Statistics Branch SP, Division of Cancer Prevention and Control, National Cancer Institute, U.S. Department of Heath and Human Services, Public Health Service, National Institutes of Health (1992) The SEER Program Code Manual In: Jack Cunningham BH, Barbara Lyles, Constance Percy, Lynn Ries, Jennifer Seiffert, Evelyn Shambaugh, Valerie Van Holten ed.: Cancer Statistics Branch, Surveillance Program, Division of Cancer Prevention and Control, National Cancer Institute, U.S. Department of Heath and Human Services, Public Health Service, National Institutes of Health"},{"key":"1962_CR29","doi-asserted-by":"publisher","first-page":"2888","DOI":"10.1200\/JCO.2016.66.8178","volume":"34","author":"N Wentzensen","year":"2016","unstructured":"Wentzensen N, Poole EM, Trabert B et al (2016) Ovarian cancer risk factors by histologic subtype: an analysis from the ovarian cancer cohort consortium. J Clin Oncol 34:2888\u20132898","journal-title":"J Clin Oncol"},{"key":"1962_CR30","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1093\/humrep\/deaa051","volume":"35","author":"KF Correia","year":"2020","unstructured":"Correia KF, Dodge LE, Farland LV et al (2020) Confounding and effect measure modification in reproductive medicine research. Hum Reprod 35:1013\u20131018","journal-title":"Hum Reprod"},{"key":"1962_CR31","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1002\/mpr.329","volume":"20","author":"MJ Azur","year":"2011","unstructured":"Azur MJ, Stuart EA, Frangakis C, Leaf PJ (2011) Multiple imputation by chained equations: what is it and how does it work? Int J Methods Psychiatr Res 20:40\u201349","journal-title":"Int J Methods Psychiatr Res"},{"key":"1962_CR32","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008215.pub3","author":"I Rizzuto","year":"2019","unstructured":"Rizzuto I, Behrens RF, Smith LA (2019) Risk of ovarian cancer in women treated with ovarian stimulating drugs for infertility. Cochrane Database Syst Rev. https:\/\/doi.org\/10.1002\/14651858.CD008215.pub3","journal-title":"Cochrane Database Syst Rev"},{"key":"1962_CR33","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.ygyno.2012.10.023","volume":"128","author":"LM Stewart","year":"2013","unstructured":"Stewart LM, Holman CD, Aboagye-Sarfo P, Finn JC, Preen DB, Hart R (2013) In vitro fertilization, endometriosis, nulliparity and ovarian cancer risk. Gynecol Oncol 128:260\u2013264","journal-title":"Gynecol Oncol"},{"key":"1962_CR34","doi-asserted-by":"publisher","first-page":"1660","DOI":"10.1016\/j.fertnstert.2013.08.008","volume":"100","author":"B Trabert","year":"2013","unstructured":"Trabert B, Lamb EJ, Scoccia B et al (2013) Ovulation-inducing drugs and ovarian cancer risk: results from an extended follow-up of a large United States infertility cohort. Fertil Steril 100:1660\u20131666","journal-title":"Fertil Steril"},{"key":"1962_CR35","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1016\/j.fertnstert.2015.12.132","volume":"105","author":"LV Farland","year":"2016","unstructured":"Farland LV, Collier AR, Correia KF et al (2016) Who receives a medical evaluation for infertility in the United States? Fertil Steril 105:1274\u20131280","journal-title":"Fertil Steril"},{"key":"1962_CR36","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1093\/humrep\/dew085","volume":"31","author":"J Prescott","year":"2016","unstructured":"Prescott J, Farland LV, Tobias DK et al (2016) A prospective cohort study of endometriosis and subsequent risk of infertility. Hum Reprod 31:1475\u20131482","journal-title":"Hum Reprod"}],"container-title":["Cancer Causes & Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-025-01962-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10552-025-01962-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-025-01962-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T08:44:13Z","timestamp":1747903453000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10552-025-01962-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,29]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["1962"],"URL":"https:\/\/doi.org\/10.1007\/s10552-025-01962-z","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"value":"0957-5243","type":"print"},{"value":"1573-7225","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,29]]},"assertion":[{"value":"26 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}