{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T10:30:56Z","timestamp":1761906656110,"version":"build-2065373602"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T00:00:00Z","timestamp":1751587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T00:00:00Z","timestamp":1751587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"National Program of Cancer Registries (NPCR) of the Centers for Disease Control and Prevention","award":["NU58DP007164"],"award-info":[{"award-number":["NU58DP007164"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Causes Control"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s10552-025-02028-w","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T22:38:20Z","timestamp":1751582300000},"page":"1361-1369","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Opioid prescription and usage disparities among Puerto Rican breast cancer survivors: findings from the Puerto Rico central cancer registry-health insurance linkage database (PRCCR-HILD)"],"prefix":"10.1007","volume":"36","author":[{"given":"Melody N.","family":"Chavez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Ortiz-Ortiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolando","family":"Trejos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Sanabria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Troy","family":"Quast","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinorah Martinez","family":"Tyson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,4]]},"reference":[{"key":"2028_CR1","doi-asserted-by":"crossref","unstructured":"Sedeta ET, Jobre B, Avezbakiyev B (2023) Breast cancer: global patterns of incidence, mortality, and trends. American Society of Clinical Oncology","DOI":"10.1200\/JCO.2023.41.16_suppl.10528"},{"issue":"6","key":"2028_CR2","first-page":"425","volume":"68","author":"KD Miller","year":"2018","unstructured":"Miller KD, Goding Sauer A, Ortiz AP, Fedewa SA, Pinheiro PS, Tortolero-Luna G et al (2018) Cancer statistics for hispanics\/latinos, 2018. CA Cancer J Clin 68(6):425\u2013445","journal-title":"CA Cancer J Clin"},{"key":"2028_CR3","unstructured":"Fagundo-Ojeda, Garc\u00eda I, Lassalle M (2022) Planning for post-disaster needs of women with breast cancer in Puerto Rico. University of Colorado Boulder"},{"issue":"3","key":"2028_CR4","first-page":"1","volume":"29","author":"M Torres-Cintr\u00f3n","year":"2010","unstructured":"Torres-Cintr\u00f3n M, Ortiz AP, P\u00e9rez-Irizarri J, Soto-Salgado M, Figueroa-Vall\u00e9s NR, De La Torre-Feliciano T et al (2010) Incidence and mortality of the leading cancer types in Puerto Rico: 1987\u20132004. P R Health Sci J 29(3):1","journal-title":"P R Health Sci J"},{"key":"2028_CR5","unstructured":"Torres-Cintr\u00f3n CR, Su\u00e1rez-Ramos T, Rom\u00e1n-Ruiz Y, Ortiz-Ortiz KJ, De Jes\u00fas-Monge V, Gierbolini-Berm\u00fadez A et al (2023) C\u00e1ncer en Puerto Rico, 2016\u20132020. San Juan, PR"},{"issue":"2","key":"2028_CR6","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1037\/lat0000055","volume":"4","author":"B Yanez","year":"2016","unstructured":"Yanez B, McGinty HL, Buitrago D, Ramirez AG, Penedo FJ (2016) Cancer outcomes in Hispanics\/Latinos in the United States: an integrative review and conceptual model of determinants of health. J Latina o Psychol 4(2):114","journal-title":"J Latina o Psychol"},{"issue":"11","key":"2028_CR7","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1007\/s11912-023-01446-w","volume":"25","author":"P Gonzalo-Encabo","year":"2023","unstructured":"Gonzalo-Encabo P, Sami N, Wilson RL, Kang D-W, Ficarra S, Dieli-Conwright CM (2023) Exercise as medicine in cardio-oncology: reducing health disparities in Hispanic and Latina breast cancer survivors. Curr Oncol Rep 25(11):1237\u20131245","journal-title":"Curr Oncol Rep"},{"key":"2028_CR8","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s10549-007-9580-1","volume":"108","author":"J Yoon","year":"2008","unstructured":"Yoon J, Malin JL, Tisnado DM, Tao ML, Adams JL, Timmer MJ et al (2008) Symptom management after breast cancer treatment: is it influenced by patient characteristics? Breast Cancer Res Treat 108:69\u201377","journal-title":"Breast Cancer Res Treat"},{"key":"2028_CR9","doi-asserted-by":"publisher","first-page":"xi41","DOI":"10.1093\/annonc\/mdt502","volume":"24","author":"J Cleary","year":"2013","unstructured":"Cleary J, De Lima L, Eisenchlas J, Radbruch L, Torode J, Cherny N (2013) Formulary availability and regulatory barriers to accessibility of opioids for cancer pain in Latin America and the Caribbean: a report from the Global Opioid Policy Initiative (GOPI). Ann Oncol 24:xi41\u2013xi50","journal-title":"Ann Oncol"},{"key":"2028_CR10","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-020-00952-1","author":"DM Tyson","year":"2021","unstructured":"Tyson DM, Chavez MN, Lake P, Gutierrez A, Sherry P, Rigg KK et al (2021) Perceptions of prescription opioid medication within the context of cancer survivorship and the opioid epidemic. J Cancer Surviv. https:\/\/doi.org\/10.1007\/s11764-020-00952-1","journal-title":"J Cancer Surviv"},{"issue":"12","key":"2028_CR11","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1200\/JCO.18.00938","volume":"37","author":"T Salz","year":"2019","unstructured":"Salz T, Lavery JA, Lipitz-Snyderman AN, Boudreau DM, Moryl N, Gillespie EF et al (2019) Trends in opioid use among older survivors of colorectal, lung, and breast cancers. J Clin Oncol 37(12):1001\u20131011","journal-title":"J Clin Oncol"},{"key":"2028_CR12","unstructured":"Administration USFaD. National drug code directory. https:\/\/www.fda.gov\/drugs\/drug-approvals-and-databases\/national-drug-code-directory2022"},{"issue":"15","key":"2028_CR13","doi-asserted-by":"publisher","first-page":"5030","DOI":"10.3390\/jcm12155030","volume":"12","author":"A Ahmed","year":"2023","unstructured":"Ahmed A, McHenry N, Gulati S, Shah I, Sheth SG (2023) Racial and ethnic disparities in opioid prescriptions for patients with abdominal pain: analysis of the National Ambulatory Medical Care Survey. J Clin Med 12(15):5030","journal-title":"J Clin Med"},{"issue":"3","key":"2028_CR14","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1002\/pds.4929","volume":"29","author":"RN Karmali","year":"2020","unstructured":"Karmali RN, Bush C, Raman SR, Campbell CI, Skinner AC, Roberts AW (2020) Long-term opioid therapy definitions and predictors: a systematic review. Pharmacoepidemiol Drug Saf 29(3):252\u2013269","journal-title":"Pharmacoepidemiol Drug Saf"},{"issue":"9","key":"2028_CR15","doi-asserted-by":"publisher","first-page":"e2016858","DOI":"10.1001\/jamanetworkopen.2020.16858","volume":"3","author":"AN Winn","year":"2020","unstructured":"Winn AN, Check DK, Farkas A, Fergestrom NM, Neuner JM, Roberts AW (2020) Association of current opioid use with serious adverse events among older adult survivors of breast cancer. JAMA Netw Open 3(9):e2016858","journal-title":"JAMA Netw Open"},{"issue":"6","key":"2028_CR16","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1002\/onco.13729","volume":"26","author":"JP Kronenfeld","year":"2021","unstructured":"Kronenfeld JP, Graves KD, Penedo FJ, Yanez B (2021) Overcoming disparities in cancer: a need for meaningful reform for Hispanic and Latino cancer survivors. Oncologist 26(6):443\u2013452","journal-title":"Oncologist"},{"issue":"9","key":"2028_CR17","doi-asserted-by":"publisher","first-page":"10851","DOI":"10.1002\/cam4.5755","volume":"12","author":"SJ Kim","year":"2023","unstructured":"Kim SJ, Retnam RP, Sutton AL, Edmonds MC, Bandyopadhyay D, Sheppard VB (2023) Racial disparities in opioid prescription and pain management among breast cancer survivors. Cancer Med 12(9):10851\u201310864","journal-title":"Cancer Med"},{"key":"2028_CR18","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.drugpo.2018.04.011","volume":"57","author":"KK Rigg","year":"2018","unstructured":"Rigg KK, Monnat SM, Chavez MN (2018) Opioid-related mortality in rural America: geographic heterogeneity and intervention strategies. Int J Drug Policy 57:119\u2013129","journal-title":"Int J Drug Policy"},{"key":"2028_CR19","unstructured":"Glassman B (2019) A thrid of movers from Uerto Rico to the mainland United STates relocated to Flroida in 2018 United States Census Bureau. https:\/\/www.census.gov\/library\/stories\/2019\/09\/puerto-rico-outmigration-increases-poverty-declines.html"},{"key":"2028_CR20","unstructured":"Oben M (2023) Investigan la escasez de medicamentos de tratamientos de quimioterapias para pacientes de c\u00e1ncer. House of Representatives of Puerto Rico. https:\/\/www.camara.pr.gov\/investigan-la-escasez-de-medicamentos-de-tratamientos-de-quimioterapias-para-pacientes-de-cancer\/"},{"key":"2028_CR21","doi-asserted-by":"publisher","first-page":"107327482211146","DOI":"10.1177\/10732748221114691","volume":"29","author":"WA Calo","year":"2022","unstructured":"Calo WA, Rivera M, Mendez-Lazaro PA, Garcia-Camacho SI, Bernhardt Utz YM, Acosta-Perez E et al (2022) Disruptions in oncology care confronted by patients with gynecologic cancer following hurricanes Irma and Maria in Puerto Rico. Cancer Control 29:10732748221114692","journal-title":"Cancer Control"},{"key":"2028_CR22","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.drugalcdep.2017.09.030","volume":"181","author":"D Hautala","year":"2017","unstructured":"Hautala D, Abadie R, Khan B, Dombrowski K (2017) Rural and urban comparisons of polysubstance use profiles and associated injection behaviors among people who inject drugs in Puerto Rico. Drug Alcohol Depend 181:186\u2013193","journal-title":"Drug Alcohol Depend"},{"issue":"2","key":"2028_CR23","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1097\/COC.0000000000000888","volume":"45","author":"M Salans","year":"2022","unstructured":"Salans M, Riviere P, Vitzthum LK, Nalawade V, Murphy JD (2022) Temporal trends and predictors of opioid use among older patients with cancer. Am J Clin Oncol 45(2):74\u201380","journal-title":"Am J Clin Oncol"},{"key":"2028_CR24","unstructured":"Bureau USC (2022) Selected characteristics of health insurance coverage in the United States. American Community Survey, ACS 1-Year Estimates Subject Tables, Table S2701. https:\/\/data.census.gov\/table\/ACSST1Y2022.S2701?q=S2701&g=040XX00US72&y=2022"},{"issue":"3","key":"2028_CR25","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1111\/1468-0009.12138","volume":"93","author":"M Portela","year":"2015","unstructured":"Portela M, Sommers BD (2015) On the outskirts of national health reform: a comparative assessment of health insurance and access to care in Puerto Rico and the United States. Milbank Q 93(3):584\u2013608","journal-title":"Milbank Q"},{"issue":"10","key":"2028_CR26","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.6004\/jnccn.2019.7305","volume":"17","author":"GL Smith","year":"2019","unstructured":"Smith GL, Lopez-Olivo MA, Advani PG, Ning MS, Geng Y, Giordano SH et al (2019) Financial burdens of cancer treatment: a systematic review of risk factors and outcomes. J Natl Compr Canc Netw 17(10):1184\u20131192","journal-title":"J Natl Compr Canc Netw"},{"issue":"1","key":"2028_CR27","doi-asserted-by":"publisher","first-page":"E96","DOI":"10.9778\/cmajo.20200076","volume":"9","author":"A B\u00e9liveau","year":"2021","unstructured":"B\u00e9liveau A, Castilloux A-M, Tannenbaum C, Vincent P, de Moura CS, Bernatsky S et al (2021) Predictors of long-term use of prescription opioids in the community-dwelling population of adults without a cancer diagnosis: a retrospective cohort study. CMAJ Open 9(1):E96\u2013E106","journal-title":"CMAJ Open"},{"key":"2028_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5888\/pcd17.190367","volume":"17","author":"MS Gallaway","year":"2020","unstructured":"Gallaway MS, Townsend JS, Shelby D, Puckett MC (2020) Peer reviewed: pain among cancer survivors. Prev Chronic Dis 17:1","journal-title":"Prev Chronic Dis"},{"issue":"11","key":"2028_CR29","doi-asserted-by":"publisher","first-page":"2532","DOI":"10.3390\/ijerph15112532","volume":"15","author":"R Ofori-Asenso","year":"2018","unstructured":"Ofori-Asenso R, Zomer E, Chin KL, Si S, Markey P, Tacey M et al (2018) Effect of comorbidity assessed by the Charlson comorbidity index on the length of stay, costs and mortality among older adults hospitalised for acute stroke. Int J Environ Res Public Health 15(11):2532","journal-title":"Int J Environ Res Public Health"},{"issue":"14","key":"2028_CR30","doi-asserted-by":"publisher","first-page":"3495","DOI":"10.7150\/jca.77108","volume":"13","author":"C Quirindongo-Rivera","year":"2022","unstructured":"Quirindongo-Rivera C, Rull\u00e1n-Varela V, Underill Z, Rivera M, Ortiz-Ortiz KJ, Mart\u00ednez-Montemayor MM (2022) Characterization of inflammatory breast cancer in Hispanic women from Puerto Rico. J Cancer 13(14):3495","journal-title":"J Cancer"},{"issue":"10","key":"2028_CR31","doi-asserted-by":"publisher","first-page":"e1574","DOI":"10.1634\/theoncologist.2019-0868","volume":"25","author":"C Shen","year":"2020","unstructured":"Shen C, Thornton JD, Gu D, Dodge D, Zhou S, He W et al (2020) Prolonged opioid use after surgery for early-stage breast cancer. Oncologist 25(10):e1574\u2013e1582","journal-title":"Oncologist"},{"issue":"1","key":"2028_CR32","first-page":"46","volume":"37","author":"VJ Gonzalez-Mercado","year":"2018","unstructured":"Gonzalez-Mercado VJ, McMillan S, Pedro E, Tirado-Gomez M, Saligan LN (2018) The health related quality of life of Puerto Ricans during cancer treatments; a pilot study. P R Health Sci J 37(1):46","journal-title":"P R Health Sci J"},{"key":"2028_CR33","doi-asserted-by":"publisher","DOI":"10.1200\/GO-24-00249","volume":"10","author":"E Morgan","year":"2024","unstructured":"Morgan E, O\u2019Neill C, Bardot A, Walsh P, Woods RR, Gonsalves L et al (2024) Collecting long-term outcomes in population-based cancer registry data: the case of breast cancer recurrence. JCO Global Oncol 10:e2400249","journal-title":"JCO Global Oncol"},{"issue":"2","key":"2028_CR34","doi-asserted-by":"publisher","first-page":"e168","DOI":"10.1200\/OP.20.00541","volume":"17","author":"KJ Ortiz-Ortiz","year":"2021","unstructured":"Ortiz-Ortiz KJ, Tortolero-Luna G, Torres-Cintr\u00f3n CR, Zavala-Zegarra DE, Gierbolini-Berm\u00fadez A, Ramos-Fern\u00e1ndez MR (2021) High-intensity end-of-life care among patients with GI cancer in Puerto Rico: a population-based study. JCO Oncol Pract 17(2):e168\u2013e177","journal-title":"JCO Oncol Pract"}],"container-title":["Cancer Causes &amp; Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-025-02028-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10552-025-02028-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10552-025-02028-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T10:26:24Z","timestamp":1761906384000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10552-025-02028-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,4]]},"references-count":34,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["2028"],"URL":"https:\/\/doi.org\/10.1007\/s10552-025-02028-w","relation":{},"ISSN":["0957-5243","1573-7225"],"issn-type":[{"type":"print","value":"0957-5243"},{"type":"electronic","value":"1573-7225"}],"subject":[],"published":{"date-parts":[[2025,7,4]]},"assertion":[{"value":"10 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"\u201cThis study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Centro Comprensivo de Cancer on 9\/18\/2019\/Pro Number: 2019-0912.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}