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This study investigated the short- and intermediate-term impact of the pandemic on cancer survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was based on cancer registry data of the Swiss cantons of Zurich and Zug from 2018 to 2021. Observed and relative one- and three-year survival were calculated based on lifetables for the population covered by the registry. Multivariable Royston Parmar survival regression models were fitted to compare survival before (2018\/2019) and during the pandemic (2020, 2021). For patients diagnosed during the pandemic, a counterfactual analysis was conducted. Analyses were performed for overall cancer and the five most common cancer types.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 32 826 cancer cases were included. One- and three-year survival for all-cancer continuously increased from 2018 to 2021. Compared to pre-pandemic, the hazard of death was lower for all-cancer during the pandemic (2020: Hazard Ratio 0.93 [95% Confidence Interval 0.89, 0.96]; 2021: 0.91 [0.87, 0.94]) and for skin melanoma in 2021 (0.79 [0.62, 0.98]), but higher for colorectal cancer during the pandemic (2020: 1.17 [1.03, 1.32]; 2021: 1.24 [1.09, 1.40]). Observed one-year survival for all-cancer, female breast, and prostate cancer was higher in 2021 than predicted. In 2020, observed one-year survival of colorectal cancer and three-year survival of female breast cancer were lower than predicted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The COVID-19 pandemic appears to have had only a minimal impact on the overall increasing cancer survival trend in Switzerland, reflecting the robustness and resilience of the healthcare system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10552-026-02175-8","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T09:56:25Z","timestamp":1779789385000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of the COVID-19 pandemic and its measures on one-year and three-year cancer survival using Swiss cantonal cancer registry data"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5302-2268","authenticated-orcid":false,"given":"Flurina","family":"Suter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0888-0690","authenticated-orcid":false,"given":"Miriam","family":"Wanner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2924-8080","authenticated-orcid":false,"given":"Andreas","family":"Wicki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9217-8038","authenticated-orcid":false,"given":"Dimitri","family":"Korol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2215-1200","authenticated-orcid":false,"given":"Sabine","family":"Rohrmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"2175_CR1","unstructured":"World Health Organization and Chinese Research Team (2021) WHO-convened Global Study of Origins of SARS-CoV-2: China Part. 2021."},{"key":"2175_CR2","unstructured":"World Health Organization (2020) Listings of WHO\u2019s response to COVID-19 2020. https:\/\/www.who.int\/news\/item\/29-06-2020-covidtimeline. 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Since 2020, all cancer cases in Switzerland are registered with presumed consent based on the Cancer Registration Act (KRG; SR 818.33). Based on this law, the patients have to be informed about the registration of their data in the cancer registry by the doctor that delivers the diagnosis, and they have the right to refuse actively. If no refusal is received by the cancer registry within three months after the first data delivery, the cancer case can be registered in the registries\u2019 database. If a refusal is received, all of the delivered data have to be deleted. All data were used anonymized in this analysis, and no approval from the Ethical Committee of the Canton of Zurich was necessary.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No AI tools were used.","order":3,"name":"Ethics","label":"Use of artificial intelligence (AI) tools","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"91"}}