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We implemented a workplace-based\n                      <jats:italic>H.pylori<\/jats:italic>\n                      screening.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>\n                      We implemented a cross-sectional screening with short-term follow-up among hospital workers (HWs), enrolled during occupational health surveillance (OHS). A stool antigen test (SAT) was adopted for\n                      <jats:italic>H.pylori<\/jats:italic>\n                      diagnosis.\n                      <jats:italic>H.pylori<\/jats:italic>\n                      -positive HWs were referred to their general practitioner (GP) or a gastroenterologist and were followed up at three months. Participation, prevalence of infection, participants\u2019 experience, and treatment rates were investigated through descriptive and multivariable analyses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>The study was carried out between 2023 and 2025 at S.Orsola University Hospital in Bologna, Italy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>The study targeted HWs aged 40\u201365 employed at S.Orsola University Hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 744 eligible HWs contacted, 550 were enrolled (73.9%), including 399 through OHS and 151 volunteers; the largest proportion of participants were women (74.7%) and nurses (40.2%). Dropout rate was 15.5% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009115), leaving 435 HWs with a SAT result.\n                      <jats:italic>H.pylori<\/jats:italic>\n                      prevalence was 16.6%. Men were less likely to participate than women (OR\u2009=\u20090.68, 95% CI\u2009=\u20090.47\u20130.99). Education was negatively associated with\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infection (OR\u2009=\u20090.41, 95% CI\u2009=\u20090.18\u20130.93 for the highest educational level vs the lowest). No specific pattern was observed in relation to contact with a physician and treatment prescription. 58\/72\n                      <jats:italic>H. pylori<\/jats:italic>\n                      -positive HWs (80.6%) contacted a physician, 53 (73.6%) being prescribed a treatment and 13 (18.1%) undergoing upper endoscopy. Confirmatory test rate after treatment was suboptimal, while eradication rate was 97.3% when considering those with confirmatory test result (36\/37 HWs). Across followed up HWs, the average quality of experience was 8.9\/10; 13 had a family member tested following this intervention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The intervention integrated into OHS was well received and extended to family members of the participants, suggesting that a workplace-based\n                      <jats:italic>H.pylori<\/jats:italic>\n                      screening might contribute to GC prevention. Replications in other workplaces are warranted.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10552-026-02189-2","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T09:31:04Z","timestamp":1785403864000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A real-world workplace-based screening for Helicobacter pylori infection: the HPOS study"],"prefix":"10.1007","volume":"37","author":[{"given":"Giulia","family":"Collatuzzo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Fiorini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Pavoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Vittoria","family":"Costanzucci Paolino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei Cosmin","family":"Siea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Zafeiratou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Astolfi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Magni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Renieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Mangiaterra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marika","family":"D\u2019Agostini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nataliia","family":"Danilevskaia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dino","family":"Vaira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Boffetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"2189_CR1","unstructured":"Occupational Safety and Health Administration\u2014OSHA. 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