{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:00:04Z","timestamp":1791198004414,"version":"4.1.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,4,22]],"date-time":"2015-04-22T00:00:00Z","timestamp":1429660800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Cardiovasc Imaging"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1007\/s10554-015-0660-8","type":"journal-article","created":{"date-parts":[[2015,4,21]],"date-time":"2015-04-21T04:40:26Z","timestamp":1429591226000},"page":"49-59","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Natural history of atherosclerotic disease progression as assessed by 18F-FDG PET\/CT"],"prefix":"10.1007","volume":"32","author":[{"given":"Holger","family":"Hetterich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Rominger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Walter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Habs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Volpers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Hacker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian F.","family":"Reiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Bartenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Saam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,4,22]]},"reference":[{"key":"660_CR1","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1161\/01.CIR.92.5.1355","volume":"92","author":"HC Stary","year":"1995","unstructured":"Stary HC, Chandler AB, Dinsmore RE et al (1995) A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 92:1355\u20131374","journal-title":"Circulation"},{"key":"660_CR2","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1161\/01.CIR.0000087480.94275.97","volume":"108","author":"M Naghavi","year":"2003","unstructured":"Naghavi M, Libby P, Falk E et al (2003) From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation 108:1664\u20131672","journal-title":"Circulation"},{"key":"660_CR3","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.1161\/CIRCULATIONAHA.107.187998","volume":"117","author":"W Rosamond","year":"2008","unstructured":"Rosamond W, Flegal K, Furie K et al (2008) Heart disease and stroke statistics\u20132008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117:e25\u2013146","journal-title":"Circulation"},{"key":"660_CR4","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1007\/s00125-013-2898-9","volume":"56","author":"HM Ruijter den","year":"2013","unstructured":"den Ruijter HM, Peters SA, Groenewegen KA et al (2013) Common carotid intima-media thickness does not add to Framingham risk score in individuals with diabetes mellitus: the USE-IMT initiative. Diabetologia 56:1494\u20131502","journal-title":"Diabetologia"},{"key":"660_CR5","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.jacc.2013.06.015","volume":"62","author":"T Saam","year":"2013","unstructured":"Saam T, Hetterich H, Hoffmann V et al (2013) Meta-analysis and systematic review of the predictive value of carotid plaque hemorrhage on cerebrovascular events by magnetic resonance imaging. J Am Coll Cardiol 62:1081\u20131091","journal-title":"J Am Coll Cardiol"},{"key":"660_CR6","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1016\/j.jacc.2010.12.043","volume":"57","author":"F Bamberg","year":"2011","unstructured":"Bamberg F, Sommer WH, Hoffmann V et al (2011) Meta-analysis and systematic review of the long-term predictive value of assessment of coronary atherosclerosis by contrast-enhanced coronary computed tomography angiography. J Am Coll Cardiol 57:2426\u20132436","journal-title":"J Am Coll Cardiol"},{"key":"660_CR7","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.jacc.2009.10.039","volume":"55","author":"BJ Chow","year":"2010","unstructured":"Chow BJ, Wells GA, Chen L et al (2010) Prognostic value of 64-slice cardiac computed tomography severity of coronary artery disease, coronary atherosclerosis, and left ventricular ejection fraction. J Am Coll Cardiol 55:1017\u20131028","journal-title":"J Am Coll Cardiol"},{"key":"660_CR8","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.jcct.2011.06.007","volume":"5","author":"Y Otaki","year":"2011","unstructured":"Otaki Y, Rajani R, Cheng VY et al (2011) The relationship between epicardial fat volume and incident coronary artery calcium. J Cardiovasc Comput Tomogr 5:310\u2013316","journal-title":"J Cardiovasc Comput Tomogr"},{"key":"660_CR9","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.2967\/jnumed.109.065151","volume":"50","author":"A Rominger","year":"2009","unstructured":"Rominger A, Saam T, Wolpers S et al (2009) 18F-FDG PET\/CT identifies patients at risk for future vascular events in an otherwise asymptomatic cohort with neoplastic disease. J Nucl Med 50:1611\u20131620","journal-title":"J Nucl Med"},{"key":"660_CR10","doi-asserted-by":"crossref","first-page":"2708","DOI":"10.1161\/01.CIR.0000020548.60110.76","volume":"105","author":"JH Rudd","year":"2002","unstructured":"Rudd JH, Warburton EA, Fryer TD et al (2002) Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography. Circulation 105:2708\u20132711","journal-title":"Circulation"},{"key":"660_CR11","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1016\/j.jacc.2006.05.076","volume":"48","author":"A Tawakol","year":"2006","unstructured":"Tawakol A, Migrino RQ, Bashian GG et al (2006) In vivo 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients. J Am Coll Cardiol 48:1818\u20131824","journal-title":"J Am Coll Cardiol"},{"key":"660_CR12","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1007\/s10554-013-0277-8","volume":"29","author":"FF Strobl","year":"2013","unstructured":"Strobl FF, Rominger A, Wolpers S et al (2013) Impact of cardiovascular risk factors on vessel wall inflammation and calcified plaque burden differs across vascular beds: a PET-CT study. Int J Cardiovasc Imaging 29:1899\u20131908","journal-title":"Int J Cardiovasc Imaging"},{"key":"660_CR13","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s11883-011-0193-0","volume":"13","author":"E Falk","year":"2011","unstructured":"Falk E, Sillesen H, Muntendam P, Fuster V (2011) The high-risk plaque initiative: primary prevention of atherothrombotic events in the asymptomatic population. Curr Atheroscler Rep 13:359\u2013366","journal-title":"Curr Atheroscler Rep"},{"key":"660_CR14","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1007\/s00259-010-1432-2","volume":"37","author":"T Saam","year":"2010","unstructured":"Saam T, Rominger A, Wolpers S et al (2010) Association of inflammation of the left anterior descending coronary artery with cardiovascular risk factors, plaque burden and pericardial fat volume: a PET\/CT study. Eur J Nucl Med Mol Imaging 37:1203\u20131212","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"660_CR15","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0735-1097(90)90282-T","volume":"15","author":"AS Agatston","year":"1990","unstructured":"Agatston AS, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte M Jr, Detrano R (1990) Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 15:827\u2013832","journal-title":"J Am Coll Cardiol"},{"key":"660_CR16","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1159\/000337083","volume":"121","author":"M Greif","year":"2012","unstructured":"Greif M, Leber AW, Saam T et al (2012) Determination of pericardial adipose tissue increases the prognostic accuracy of coronary artery calcification for future cardiovascular events. Cardiology 121:220\u2013227","journal-title":"Cardiology"},{"key":"660_CR17","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1161\/ATVBAHA.108.180653","volume":"29","author":"M Greif","year":"2009","unstructured":"Greif M, Becker A, von Ziegler F et al (2009) Pericardial adipose tissue determined by dual source CT is a risk factor for coronary atherosclerosis. Arterioscler Thromb Vasc Biol 29:781\u2013786","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"660_CR18","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1161\/CIRCULATIONAHA.106.674143","volume":"115","author":"RA Kronmal","year":"2007","unstructured":"Kronmal RA, McClelland RL, Detrano R et al (2007) Risk factors for the progression of coronary artery calcification in asymptomatic subjects: results from the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation 115:2722\u20132730","journal-title":"Circulation"},{"key":"660_CR19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1161\/CIRCULATIONAHA.106.658583","volume":"116","author":"AE Cassidy-Bushrow","year":"2007","unstructured":"Cassidy-Bushrow AE, Bielak LF, Sheedy PF II et al (2007) Coronary artery calcification progression is heritable. Circulation 116:25\u201331","journal-title":"Circulation"},{"key":"660_CR20","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s10554-014-0542-5","volume":"31","author":"N Tomizawa","year":"2015","unstructured":"Tomizawa N, Nojo T, Inoh S, Nakamura S (2015) Difference of coronary artery disease severity, extent and plaque characteristics between patients with hypertension, diabetes mellitus or dyslipidemia. Int J Cardiovasc Imaging 31:205\u2013212","journal-title":"Int J Cardiovasc Imaging"},{"key":"660_CR21","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s10554-011-9851-0","volume":"28","author":"M Hadamitzky","year":"2012","unstructured":"Hadamitzky M, Meyer T, Hein F et al (2012) Prognostic value of coronary computed tomographic angiography in patients with arterial hypertension. Int J Cardiovasc Imaging 28:641\u2013650","journal-title":"Int J Cardiovasc Imaging"},{"key":"660_CR22","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.atherosclerosis.2012.12.017","volume":"227","author":"MJ Gils van","year":"2013","unstructured":"van Gils MJ, Bodde MC, Cremers LG, Dippel DW, van der Lugt A (2013) Determinants of calcification growth in atherosclerotic carotid arteries; a serial multi-detector CT angiography study. Atherosclerosis 227:95\u201399","journal-title":"Atherosclerosis"},{"key":"660_CR23","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1007\/s00330-009-1394-6","volume":"19","author":"S Rozie","year":"2009","unstructured":"Rozie S, de Weert TT, de Monye C et al (2009) Atherosclerotic plaque volume and composition in symptomatic carotid arteries assessed with multidetector CT angiography; relationship with severity of stenosis and cardiovascular risk factors. Eur Radiol 19:2294\u20132301","journal-title":"Eur Radiol"},{"key":"660_CR24","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1161\/CIRCULATIONAHA.110.966465","volume":"122","author":"M Juonala","year":"2010","unstructured":"Juonala M, Magnussen CG, Venn A et al (2010) Influence of age on associations between childhood risk factors and carotid intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Bogalusa Heart Study, and the Muscatine Study for the International Childhood Cardiovascular Cohort (i3C) Consortium. Circulation 122:2514\u20132520","journal-title":"Circulation"},{"key":"660_CR25","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1093\/aje\/155.1.38","volume":"155","author":"LE Chambless","year":"2002","unstructured":"Chambless LE, Folsom AR, Davis V et al (2002) Risk factors for progression of common carotid atherosclerosis: the Atherosclerosis Risk in Communities Study, 1987\u20131998. Am J Epidemiol 155:38\u201347","journal-title":"Am J Epidemiol"},{"key":"660_CR26","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1177\/000331970205300108","volume":"53","author":"Y Arai","year":"2002","unstructured":"Arai Y, Hirose N, Yamamura K et al (2002) Long-term effect of lipid-lowering therapy on atherosclerosis of abdominal aorta in patients with hypercholesterolemia: noninvasive evaluation by a new image analysis program. Angiology 53:57\u201368","journal-title":"Angiology"},{"key":"660_CR27","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0021-9150(94)90202-X","volume":"110","author":"J Takasu","year":"1994","unstructured":"Takasu J, Masuda Y, Watanabe S et al (1994) Progression and regression of atherosclerotic findings in the descending thoracic aorta detected by enhanced computed tomography. Atherosclerosis 110:175\u2013184","journal-title":"Atherosclerosis"},{"key":"660_CR28","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1161\/ATVBAHA.114.303035","volume":"34","author":"S Lim","year":"2014","unstructured":"Lim S, Meigs JB (2014) Links between ectopic fat and vascular disease in humans. Arterioscler Thromb Vasc Biol 34:1820\u20131826","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"660_CR29","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.atherosclerosis.2011.09.041","volume":"220","author":"A Yerramasu","year":"2012","unstructured":"Yerramasu A, Dey D, Venuraju S et al (2012) Increased volume of epicardial fat is an independent risk factor for accelerated progression of sub-clinical coronary atherosclerosis. Atherosclerosis 220:223\u2013230","journal-title":"Atherosclerosis"},{"key":"660_CR30","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.atherosclerosis.2011.07.093","volume":"218","author":"R Nakanishi","year":"2011","unstructured":"Nakanishi R, Rajani R, Cheng VY et al (2011) Increase in epicardial fat volume is associated with greater coronary artery calcification progression in subjects at intermediate risk by coronary calcium score: a serial study using non-contrast cardiac CT. Atherosclerosis 218:363\u2013368","journal-title":"Atherosclerosis"},{"key":"660_CR31","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.ahj.2007.03.019","volume":"153","author":"HS Sacks","year":"2007","unstructured":"Sacks HS, Fain JN (2007) Human epicardial adipose tissue: a review. Am Heart J 153:907\u2013917","journal-title":"Am Heart J"},{"key":"660_CR32","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s12350-012-9631-9","volume":"19","author":"MS Cocker","year":"2012","unstructured":"Cocker MS, Mc Ardle B, Spence JD et al (2012) Imaging atherosclerosis with hybrid [(18)F]fluorodeoxyglucose positron emission tomography\/computed tomography imaging: what Leonardo da Vinci could not see. J Nucl Cardiol 19:1211\u20131225","journal-title":"J Nucl Cardiol"},{"key":"660_CR33","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1161\/01.ATV.0000251503.35795.4f","volume":"27","author":"W Koenig","year":"2007","unstructured":"Koenig W, Khuseyinova N (2007) Biomarkers of atherosclerotic plaque instability and rupture. Arterioscler Thromb Vasc Biol 27:15\u201326","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"660_CR34","first-page":"608","volume":"46","author":"G Brix","year":"2005","unstructured":"Brix G, Lechel U, Glatting G et al (2005) Radiation exposure of patients undergoing whole-body dual-modality 18F-FDG PET\/CT examinations. J Nucl Med 46:608\u2013613","journal-title":"J Nucl Med"},{"key":"660_CR35","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1016\/j.jacc.2006.03.069","volume":"48","author":"N Tahara","year":"2006","unstructured":"Tahara N, Kai H, Ishibashi M et al (2006) Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography. J Am Coll Cardiol 48:1825\u20131831","journal-title":"J Am Coll Cardiol"},{"key":"660_CR36","doi-asserted-by":"crossref","first-page":"871","DOI":"10.2967\/jnumed.107.050294","volume":"49","author":"JH Rudd","year":"2008","unstructured":"Rudd JH, Myers KS, Bansilal S et al (2008) Atherosclerosis inflammation imaging with 18F-FDG PET: carotid, iliac, and femoral uptake reproducibility, quantification methods, and recommendations. J Nucl Med 49:871\u2013878","journal-title":"J Nucl Med"}],"container-title":["The International Journal of Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-015-0660-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10554-015-0660-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-015-0660-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T17:13:42Z","timestamp":1559236422000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10554-015-0660-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,22]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["660"],"URL":"https:\/\/doi.org\/10.1007\/s10554-015-0660-8","relation":{},"ISSN":["1569-5794","1573-0743"],"issn-type":[{"value":"1569-5794","type":"print"},{"value":"1573-0743","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,22]]}}}