{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T20:07:59Z","timestamp":1788898079209,"version":"build-2803163510"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2016,10,25]],"date-time":"2016-10-25T00:00:00Z","timestamp":1477353600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Cardiovasc Imaging"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1007\/s10554-016-1004-z","type":"journal-article","created":{"date-parts":[[2016,10,25]],"date-time":"2016-10-25T08:02:25Z","timestamp":1477382545000},"page":"313-321","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Right ventricular relative wall thickness as a predictor of outcomes and of right ventricular reverse remodeling for patients with pulmonary hypertension"],"prefix":"10.1007","volume":"33","author":[{"given":"Hiroyuki","family":"Sano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidekazu","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiki","family":"Motoji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhide","family":"Mochizuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Hatani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Matsuzoe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Hatazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Shimoura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junichi","family":"Ooka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Ryo-Koriyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiko","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Emoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken-ichi","family":"Hirata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,10,25]]},"reference":[{"key":"1004_CR1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/eurheartj\/ehv317","volume":"37","author":"N Galie","year":"2016","unstructured":"Galie N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, Simonneau G, Peacock A, Vonk Noordegraaf A, Beghetti M, Ghofrani A, Gomez Sanchez MA, Hansmann G, Klepetko W, Lancellotti P, Matucci M, McDonagh T, Pierard LA, Trindade PT, Zompatori M, Hoeper M, Aboyans V, Vaz Carneiro A, Achenbach S, Agewall S, Allanore Y, Asteggiano R, Paolo Badano L, Albert Barbera J, Bouvaist H, Bueno H, Byrne RA, Carerj S, Castro G, Erol C, Falk V, Funck-Brentano C, Gorenflo M, Granton J, Iung B, Kiely DG, Kirchhof P, Kjellstrom B, Landmesser U, Lekakis J, Lionis C, Lip GY, Orfanos SE, Park MH, Piepoli MF, Ponikowski P, Revel MP, Rigau D, Rosenkranz S, Voller H, Luis Zamorano J (2016) 2015 ESC\/ERS guidelines for the diagnosis and treatment of pulmonary hypertension: the joint task force for the diagnosis and treatment of pulmonary hypertension of the European Society Of Cardiology (ESC) and the European Respiratory Society (ERS): endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Heart J 37:67\u2013119","journal-title":"Eur Heart J"},{"key":"1004_CR2","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1164\/rccm.200604-547OC","volume":"174","author":"PR Forfia","year":"2006","unstructured":"Forfia PR, Fisher MR, Mathai SC, Housten-Harris T, Hemnes AR, Borlaug BA, Chamera E, Corretti MC, Champion HC, Abraham TP, Girgis RE, Hassoun PM (2006) Tricuspid annular displacement predicts survival in pulmonary hypertension. Am J Respir Crit Care Med 174:1034\u20131041","journal-title":"Am J Respir Crit Care Med"},{"key":"1004_CR3","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.ijcard.2008.11.051","volume":"140","author":"S Ghio","year":"2010","unstructured":"Ghio S, Klersy C, Magrini G, D\u2019Armini AM, Scelsi L, Raineri C, Pasotti M, Serio A, Campana C, Vigano M (2010) Prognostic relevance of the echocardiographic assessment of right ventricular function in patients with idiopathic pulmonary arterial hypertension. Int J Cardiol 140:272\u2013278","journal-title":"Int J Cardiol"},{"key":"1004_CR4","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1161\/CIRCIMAGING.113.000640","volume":"6","author":"NM Fine","year":"2013","unstructured":"Fine NM, Chen L, Bastiansen PM, Frantz RP, Pellikka PA, Oh JK, Kane GC (2013) Outcome prediction by quantitative right ventricular function assessment in 575 subjects evaluated for pulmonary hypertension. Circ Cardiovasc Imaging 6:711\u2013721","journal-title":"Circ Cardiovasc Imaging"},{"key":"1004_CR5","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1161\/CIRCIMAGING.111.971465","volume":"5","author":"ML Haeck","year":"2012","unstructured":"Haeck ML, Scherptong RW, Marsan NA, Holman ER, Schalij MJ, Bax JJ, Vliegen HW, Delgado V (2012) Prognostic value of right ventricular longitudinal peak systolic strain in patients with pulmonary hypertension. Circ Cardiovasc Imaging 5:628\u2013636","journal-title":"Circ Cardiovasc Imaging"},{"issue":"1\u201339","key":"1004_CR6","first-page":"e14","volume":"28","author":"RM Lang","year":"2015","unstructured":"Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P, Muraru D, Picard MH, Rietzschel ER, Rudski L, Spencer KT, Tsang W, Voigt JU (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 28(1\u201339):e14","journal-title":"J Am Soc Echocardiogr"},{"key":"1004_CR7","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1253\/circj.CJ-12-1083","volume":"77","author":"Y Motoji","year":"2013","unstructured":"Motoji Y, Tanaka H, Fukuda Y, Ryo K, Emoto N, Kawai H, Hirata K (2013) Efficacy of right ventricular free-wall longitudinal speckle-tracking strain for predicting long-term outcome in patients with pulmonary hypertension. Circ J 77:756\u2013763","journal-title":"Circ J"},{"key":"1004_CR8","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1183\/09031936.02.00068002","volume":"20","author":"D Chemla","year":"2002","unstructured":"Chemla D, Castelain V, Herve P, Lecarpentier Y, Brimioulle S (2002) Haemodynamic evaluation of pulmonary hypertension. Eur Respir J 20:1314\u20131331","journal-title":"Eur Respir J"},{"key":"1004_CR9","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/00019501-200502000-00003","volume":"16","author":"KM Chin","year":"2005","unstructured":"Chin KM, Kim NH, Rubin LJ (2005) The right ventricle in pulmonary hypertension. Coron Artery Dis 16:13\u201318","journal-title":"Coron Artery Dis"},{"key":"1004_CR10","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.cjca.2015.01.027","volume":"31","author":"H Sano","year":"2015","unstructured":"Sano H, Tanaka H, Motoji Y, Fukuda Y, Sawa T, Mochizuki Y, Ryo K, Matsumoto K, Emoto N, Hirata K (2015) Right ventricular function and right-heart echocardiographic response to therapy predict long-term outcome in patients with pulmonary hypertension. Can J Cardiol 31:529\u2013536","journal-title":"Can J Cardiol"},{"key":"1004_CR11","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1093\/eurheartj\/ehp297","volume":"30","author":"N Galie","year":"2009","unstructured":"Galie N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA, Beghetti M, Corris P, Gaine S, Gibbs JS, Gomez-Sanchez MA, Jondeau G, Klepetko W, Opitz C, Peacock A, Rubin L, Zellweger M, Simonneau G, Guidelines ESCCfP (2009) Guidelines for the diagnosis and treatment of pulmonary hypertension: the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 30:2493\u20132537","journal-title":"Eur Heart J"},{"key":"1004_CR12","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/0002-9149(87)91004-6","volume":"60","author":"AS Pearlman","year":"1987","unstructured":"Pearlman AS, Gardin JM, Martin RP, Parisi AF, Popp RL, Quinones MA, Stevenson JG (1987) Guidelines for optimal physician training in echocardiography. Recommendations of the American society of echocardiography committee for physician training in echocardiography. Am J Cardiol 60:158\u2013163","journal-title":"Am J Cardiol"},{"key":"1004_CR13","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/j.echo.2011.06.005","volume":"24","author":"Y Fukuda","year":"2011","unstructured":"Fukuda Y, Tanaka H, Sugiyama D, Ryo K, Onishi T, Fukuya H, Nogami M, Ohno Y, Emoto N, Kawai H, Hirata K (2011) Utility of right ventricular free wall speckle-tracking strain for evaluation of right ventricular performance in patients with pulmonary hypertension. J Am Soc Echocardiogr 24:1101\u20131108","journal-title":"J Am Soc Echocardiogr"},{"key":"1004_CR14","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/echo.13036","volume":"33","author":"Y Motoji","year":"2016","unstructured":"Motoji Y, Tanaka H, Fukuda Y, Sano H, Ryo K, Sawa T, Miyoshi T, Imanishi J, Mochizuki Y, Tatsumi K, Matsumoto K, Emoto N, Hirata K (2016) Association of apical longitudinal rotation with right ventricular performance in patients with pulmonary hypertension: insights into overestimation of tricuspid annular plane systolic excursion. Echocardiography 33:207\u2013215","journal-title":"Echocardiography"},{"key":"1004_CR15","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1007\/s10554-014-0460-6","volume":"30","author":"Y Fukuda","year":"2014","unstructured":"Fukuda Y, Tanaka H, Motoji Y, Ryo K, Sawa T, Imanishi J, Miyoshi T, Mochizuki Y, Tatsumi K, Matsumoto K, Shinke T, Emoto N, Hirata K (2014) Utility of combining assessment of right ventricular function and right atrial remodeling as a prognostic factor for patients with pulmonary hypertension. Int J Cardiovasc Imaging 30:1269\u20131277","journal-title":"Int J Cardiovasc Imaging"},{"key":"1004_CR16","doi-asserted-by":"publisher","DOI":"10.1111\/echo.13205","author":"Y Fukuda","year":"2016","unstructured":"Fukuda Y, Tanaka H, Ryo-Koriyama K, Motoji Y, Sano H, Shimoura H, Ooka J, Toki H, Sawa T, Mochizuki Y, Matsumoto K, Emoto N, Hirata K (2016) Comprehensive functional assessment of right-sided heart using speckle tracking strain for patients with pulmonary hypertension. Echocardiography. doi: 10.1111\/echo.13205","journal-title":"Echocardiography"},{"key":"1004_CR17","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s10554-015-0598-x","volume":"31","author":"Y Motoji","year":"2015","unstructured":"Motoji Y, Tanaka H, Fukuda Y, Sano H, Ryo K, Imanishi J, Miyoshi T, Sawa T, Mochizuki Y, Matsumoto K, Emoto N, Hirata K (2015) Interdependence of right ventricular systolic function and left ventricular filling and its association with outcome for patients with pulmonary hypertension. Int J Cardiovasc Imaging 31:691\u2013698","journal-title":"Int J Cardiovasc Imaging"},{"key":"1004_CR18","doi-asserted-by":"crossref","first-page":"D22","DOI":"10.1016\/j.jacc.2013.10.027","volume":"62","author":"A Vonk-Noordegraaf","year":"2013","unstructured":"Vonk-Noordegraaf A, Haddad F, Chin KM, Forfia PR, Kawut SM, Lumens J, Naeije R, Newman J, Oudiz RJ, Provencher S, Torbicki A, Voelkel NF, Hassoun PM (2013) Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology. J Am Coll Cardiol 62:D22\u2013D33","journal-title":"J Am Coll Cardiol"},{"key":"1004_CR19","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1086\/679699","volume":"5","author":"A Harrison","year":"2015","unstructured":"Harrison A, Hatton N, Ryan JJ (2015) The right ventricle under pressure: evaluating the adaptive and maladaptive changes in the right ventricle in pulmonary arterial hypertension using echocardiography (2013 Grover Conference series). Pulm Circ 5:29\u201347","journal-title":"Pulm Circ"},{"key":"1004_CR20","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.cjca.2015.01.023","volume":"31","author":"JJ Ryan","year":"2015","unstructured":"Ryan JJ, Huston J, Kutty S, Hatton ND, Bowman L, Tian L, Herr JE, Johri AM, Archer SL (2015) Right ventricular adaptation and failure in pulmonary arterial hypertension. Can J Cardiol 31:391\u2013406","journal-title":"Can J Cardiol"},{"key":"1004_CR21","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1183\/09059180.00006511","volume":"20","author":"A Vonk Noordegraaf","year":"2011","unstructured":"Vonk Noordegraaf A, Galie N (2011) The role of the right ventricle in pulmonary arterial hypertension. Eur Respir Rev 20:243\u2013253","journal-title":"Eur Respir Rev"},{"key":"1004_CR22","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1007\/s00109-013-1064-7","volume":"91","author":"L Piao","year":"2013","unstructured":"Piao L, Fang YH, Parikh K, Ryan JJ, Toth PT, Archer SL (2013) Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension. J Mol Med 91:1185\u20131197","journal-title":"J Mol Med"},{"key":"1004_CR23","doi-asserted-by":"crossref","first-page":"2859","DOI":"10.1161\/CIRCULATIONAHA.112.109868","volume":"126","author":"L Piao","year":"2012","unstructured":"Piao L, Fang YH, Parikh KS, Ryan JJ, D\u2019Souza KM, Theccanat T, Toth PT, Pogoriler J, Paul J, Blaxall BC, Akhter SA, Archer SL (2012) GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation 126:2859\u20132869","journal-title":"Circulation"},{"key":"1004_CR24","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1378\/chest.08-0492","volume":"135","author":"HJ Bogaard","year":"2009","unstructured":"Bogaard HJ, Abe K, Vonk Noordegraaf A, Voelkel NF (2009) The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension. Chest 135:794\u2013804","journal-title":"Chest"},{"key":"1004_CR25","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1161\/CIRCRESAHA.113.301129","volume":"115","author":"JJ Ryan","year":"2014","unstructured":"Ryan JJ, Archer SL (2014) The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure. Circ Res 115:176\u2013188","journal-title":"Circ Res"},{"key":"1004_CR26","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.healun.2014.11.002","volume":"34","author":"R Badagliacca","year":"2015","unstructured":"Badagliacca R, Poscia R, Pezzuto B, Nocioni M, Mezzapesa M, Francone M, Giannetta E, Papa S, Gambardella C, Sciomer S, Volterrani M, Fedele F, Dario Vizza C (2015) Right ventricular remodeling in idiopathic pulmonary arterial hypertension: adaptive versus maladaptive morphology. J Heart Lung Transplant 34:395\u2013403","journal-title":"J Heart Lung Transplant"},{"key":"1004_CR27","doi-asserted-by":"crossref","first-page":"e0119277","DOI":"10.1371\/journal.pone.0119277","volume":"10","author":"J Steiner","year":"2015","unstructured":"Steiner J, Wu WC, Jankowich M, Maron BA, Sharma S, Choudhary G (2015) Echocardiographic predictors of mortality in patients with pulmonary hypertension and cardiopulmonary comorbidities. PLoS One 10:e0119277","journal-title":"PLoS One"},{"key":"1004_CR28","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1183\/09031936.00012914","volume":"43","author":"S Fukui","year":"2014","unstructured":"Fukui S, Ogo T, Morita Y, Tsuji A, Tateishi E, Ozaki K, Sanda Y, Fukuda T, Yasuda S, Ogawa H, Nakanishi N (2014) Right ventricular reverse remodelling after balloon pulmonary angioplasty. Eur Respir J 43:1394\u20131402","journal-title":"Eur Respir J"},{"key":"1004_CR29","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1007\/s00330-007-0829-1","volume":"18","author":"M Iino","year":"2008","unstructured":"Iino M, Dymarkowski S, Chaothawee L, Delcroix M, Bogaert J (2008) Time course of reversed cardiac remodeling after pulmonary endarterectomy in patients with chronic pulmonary thromboembolism. Eur Radiol 18:792\u2013799","journal-title":"Eur Radiol"},{"key":"1004_CR30","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1086\/674884","volume":"4","author":"M Berman","year":"2014","unstructured":"Berman M, Gopalan D, Sharples L, Screaton N, Maccan C, Sheares K, Pepke-Zaba J, Dunning J, Tsui S, Jenkins DP (2014) Right ventricular reverse remodeling after pulmonary endarterectomy: magnetic resonance imaging and clinical and right heart catheterization assessment. Pulm Circ 4:36\u201344","journal-title":"Pulm Circ"},{"key":"1004_CR31","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jacc.2014.01.084","volume":"64","author":"BC Smith","year":"2014","unstructured":"Smith BC, Dobson G, Dawson D, Charalampopoulos A, Grapsa J, Nihoyannopoulos P (2014) Three-dimensional speckle tracking of the right ventricle: toward optimal quantification of right ventricular dysfunction in pulmonary hypertension. J Am Coll Cardiol 64:41\u201351","journal-title":"J Am Coll Cardiol"},{"key":"1004_CR32","doi-asserted-by":"crossref","first-page":"e001584","DOI":"10.1161\/JAHA.114.001584","volume":"4","author":"A Vitarelli","year":"2015","unstructured":"Vitarelli A, Mangieri E, Terzano C, Gaudio C, Salsano F, Rosato E, Capotosto L, D\u2019Orazio S, Azzano A, Truscelli G, Cocco N, Ashurov R (2015) Three-dimensional echocardiography and 2D-3D speckle-tracking imaging in chronic pulmonary hypertension: diagnostic accuracy in detecting hemodynamic signs of right ventricular (RV) failure. J Am Heart Assoc 4:e001584","journal-title":"J Am Heart Assoc"}],"container-title":["The International Journal of Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-016-1004-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10554-016-1004-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-016-1004-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T02:01:19Z","timestamp":1498356079000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10554-016-1004-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,25]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["1004"],"URL":"https:\/\/doi.org\/10.1007\/s10554-016-1004-z","relation":{},"ISSN":["1569-5794","1573-0743"],"issn-type":[{"value":"1569-5794","type":"print"},{"value":"1573-0743","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,25]]}}}