{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T01:47:04Z","timestamp":1791942424028,"version":"4.3.4"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T00:00:00Z","timestamp":1557878400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T00:00:00Z","timestamp":1557878400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Cardiovasc Imaging"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1007\/s10554-019-01554-4","type":"journal-article","created":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T11:54:13Z","timestamp":1557921253000},"page":"1319-1325","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["T1 reactivity as an imaging biomarker in myocardial tissue characterization discriminating normal, ischemic and infarcted myocardium"],"prefix":"10.1007","volume":"35","author":[{"given":"Marly","family":"van Assen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randy","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirkjan","family":"Kuijpers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rozemarijn","family":"Vliegenthart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthijs","family":"Oudkerk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,5,15]]},"reference":[{"key":"1554_CR1","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/1532-429X-15-92","volume":"15","author":"JC Moon","year":"2013","unstructured":"Moon JC, Messroghli DR, Kellman P, Piechnik SK, Robson MD, Ugander M et al (2013) Myocardial T1 mapping and extracellular volume quantification: a Society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the European Society of Cardiology consensus statement. J Cardiovasc Magn Reson 15:92. \n                    https:\/\/doi.org\/10.1186\/1532-429X-15-92","journal-title":"J Cardiovasc Magn Reson"},{"key":"1554_CR2","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.jcmg.2013.06.008","volume":"7","author":"F Bamberg","year":"2014","unstructured":"Bamberg F, Marcus RP, Becker A, Hildebrandt K, Bauner K, Schwarz F et al (2014) Dynamic myocardial CT perfusion imaging for evaluation of myocardial ischemia as determined by MR imaging. JACC Cardiovasc Imaging 7:267\u2013277. \n                    https:\/\/doi.org\/10.1016\/j.jcmg.2013.06.008","journal-title":"JACC Cardiovasc Imaging"},{"key":"1554_CR3","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1093\/ehjci\/jeu024","volume":"15","author":"D H-Ici","year":"2014","unstructured":"H-Ici D, Jeuthe S, Al-Wakeel N, Berger F, Kuehne T, Kozerke S et al (2014) T1 mapping in ischaemic heart disease. Eur Heart J Cardiovasc Imaging 15:597\u2013602. \n                    https:\/\/doi.org\/10.1093\/ehjci\/jeu024","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"1554_CR4","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1161\/CIRCRESAHA.116.307974","volume":"119","author":"VO Puntmann","year":"2016","unstructured":"Puntmann VO, Peker E, Chandrashekhar Y, Nagel E (2016) T1 mapping in characterizing myocardial disease: a comprehensive review. Circ Res 119:277\u2013299. \n                    https:\/\/doi.org\/10.1161\/CIRCRESAHA.116.307974","journal-title":"Circ Res"},{"key":"1554_CR5","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1007\/s10554-016-0949-2","volume":"32","author":"D Kuijpers","year":"2016","unstructured":"Kuijpers D, Prakken NH, Vliegenthart R, van Dijkman PRM, van der Harst P, Oudkerk M (2016) Caffeine intake inverts the effect of adenosine on myocardial perfusion during stress as measured by T1 mapping. Int J Cardiovasc Imaging 32:1545\u20131553. \n                    https:\/\/doi.org\/10.1007\/s10554-016-0949-2","journal-title":"Int J Cardiovasc Imaging"},{"key":"1554_CR6","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.jcmg.2015.08.018","volume":"9","author":"A Liu","year":"2016","unstructured":"Liu A, Wijesurendra RS, Francis JM, Robson MD, Neubauer S, Piechnik SK et al (2016) Adenosine stress and rest T1 mapping can differentiate between ischemic, lnfarcted, remote, and normal myocardium without the need for gadolinium contrast agents. JACC Cardiovasc Imaging 9:27\u201336. \n                    https:\/\/doi.org\/10.1016\/j.jcmg.2015.08.018","journal-title":"JACC Cardiovasc Imaging"},{"key":"1554_CR7","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s10554-010-9775-0","volume":"28","author":"DD Lubbers","year":"2012","unstructured":"Lubbers DD, Rijlaarsdam-Hermsen D, Kuijpers D, Kerkhof M, Sijens PE, van Dijkman PRM et al (2012) Performance of adenosine \u201cstress-only\u201d perfusion MRI in patients without a history of myocardial infarction: a clinical outcome study. Int J Cardiovasc Imaging 28:109\u2013115. \n                    https:\/\/doi.org\/10.1007\/s10554-010-9775-0","journal-title":"Int J Cardiovasc Imaging"},{"issue":"Suppl 1","key":"1554_CR8","doi-asserted-by":"publisher","first-page":"P49","DOI":"10.1186\/1532-429X-17-S1-P49","volume":"17","author":"N Child","year":"2015","unstructured":"Child N, Yap ML, Dabir D, Rogers T, Suna G, Higgins DM et al (2015) T1 values by conservative septal postprocessing approach are superior in relating to the interstitial myocardial fibrosis: findings from patients with severe aortic stenosis. J Cardiovasc Magn Reson 17(Suppl 1):P49. \n                    https:\/\/doi.org\/10.1186\/1532-429X-17-S1-P49","journal-title":"J Cardiovasc Magn Reson"},{"key":"1554_CR9","doi-asserted-by":"publisher","first-page":"1954","DOI":"10.1016\/j.jacc.2012.01.055","volume":"59","author":"JR Arnold","year":"2012","unstructured":"Arnold JR, Karamitsos TD, Bhamra-Ariza P, Francis JM, Searle N, Robson MD et al (2012) Myocardial oxygenation in coronary artery disease: insights from blood oxygen level-dependent magnetic resonance imaging at 3 T. J Am Coll Cardiol 59:1954\u20131964. \n                    https:\/\/doi.org\/10.1016\/j.jacc.2012.01.055","journal-title":"J Am Coll Cardiol"},{"key":"1554_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1532-429X-16-1","volume":"16","author":"P Kellman","year":"2014","unstructured":"Kellman P, Hansen MS (2014) T1-mapping in the heart: accuracy and precision. J Cardiovasc Magn Reson 16:1\u201320. \n                    https:\/\/doi.org\/10.1186\/1532-429X-16-2","journal-title":"J Cardiovasc Magn Reson"},{"key":"1554_CR11","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1002\/mrm.21272","volume":"58","author":"DR Messroghli","year":"2007","unstructured":"Messroghli DR, Walters K, Plein S, Sparrow P, Friedrich MG, Ridgway JP et al (2007) Myocardial T1 mapping: application to patients with acute and chronic myocardial infarction. Magn Reson Med 58:34\u201340. \n                    https:\/\/doi.org\/10.1002\/mrm.21272\n                    \n                   doi","journal-title":"Magn Reson Med"},{"key":"1554_CR12","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1136\/heartjnl-2012-303052","volume":"99","author":"S Bull","year":"2013","unstructured":"Bull S, White SK, Piechnik SK, Flett AS, Ferreira VM, Loudon M et al (2013) Human non-contrast T1 values and correlation with histology in diffuse fibrosis. Heart 99:932\u2013937. \n                    https:\/\/doi.org\/10.1136\/heartjnl-2012-303052","journal-title":"Heart"},{"key":"1554_CR13","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1016\/j.crad.2016.02.013","volume":"71","author":"RJ Everett","year":"2016","unstructured":"Everett RJ, Stirrat CG, Semple SIR, Newby DE, Dweck MR, Mirsadraee S (2016) Assessment of myocardial fibrosis with T1 mapping MRI. Clin Radiol 71:768\u2013778. \n                    https:\/\/doi.org\/10.1016\/j.crad.2016.02.013","journal-title":"Clin Radiol"},{"key":"1554_CR14","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1148\/radiol.13131669","volume":"270","author":"T Kanda","year":"2014","unstructured":"Kanda T, Ishii K, Kawaguchi H, Kitajima K, Takenaka D (2014) High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images: relationship with increasing cumulative dose of a gadolinium-based contrast material. Radiology 270:834\u2013841. \n                    https:\/\/doi.org\/10.1148\/radiol.13131669","journal-title":"Radiology"},{"key":"1554_CR15","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.15150025","author":"RJ McDonald","year":"2015","unstructured":"McDonald RJ, McDonald JS, Kallmes DF, Jentoft ME, Murray DL, Thielen KR et al (2015) Intracranial gadolinium deposition after contrast-enhanced MR imaging. Radiology. \n                    https:\/\/doi.org\/10.1148\/radiol.15150025","journal-title":"Radiology"}],"container-title":["The International Journal of Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-019-01554-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10554-019-01554-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-019-01554-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,13]],"date-time":"2020-05-13T23:24:19Z","timestamp":1589412259000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10554-019-01554-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,15]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["1554"],"URL":"https:\/\/doi.org\/10.1007\/s10554-019-01554-4","relation":{},"ISSN":["1569-5794","1573-0743"],"issn-type":[{"value":"1569-5794","type":"print"},{"value":"1573-0743","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,15]]},"assertion":[{"value":"18 July 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 February 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All authors have reported that they have no relationships to disclose relevant to this paper. The UMCG receives institutional research support from Siemens.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}