{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:35:37Z","timestamp":1784298937176,"version":"3.55.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T00:00:00Z","timestamp":1559088000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T00:00:00Z","timestamp":1559088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL115828"],"award-info":[{"award-number":["R01HL115828"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL133504"],"award-info":[{"award-number":["R01HL133504"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Cardiovasc Imaging"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1007\/s10554-019-01632-7","type":"journal-article","created":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T14:22:32Z","timestamp":1559139752000},"page":"1925-1934","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Interval changes in aortic peak velocity and wall shear stress in patients with bicuspid aortic valve disease"],"prefix":"10.1007","volume":"35","author":[{"given":"Ozair","family":"Rahman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Bollache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Suwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Carr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Fedak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"McCarthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Malaisrie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex J.","family":"Barker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Markl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,5,29]]},"reference":[{"issue":"25","key":"1632_CR1","doi-asserted-by":"publisher","first-page":"2789","DOI":"10.1016\/j.jacc.2009.12.068","volume":"55","author":"SC Siu","year":"2010","unstructured":"Siu SC, Silversides CK (2010) Bicuspid aortic valve disease. J Am Coll Cardiol 55(25):2789\u20132800","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"1632_CR2","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1161\/CIRCULATIONAHA.113.003026","volume":"129","author":"R Mahadevia","year":"2014","unstructured":"Mahadevia R, Barker AJ, Schnell S et al (2014) Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy. Circulation 129(6):673\u2013682","journal-title":"Circulation"},{"issue":"2","key":"1632_CR3","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1093\/ejcts\/ezt610","volume":"46","author":"E. Girdauskas","year":"2014","unstructured":"Girdauskas E, Rouman M, Disha K, et al (2014) Correlation between systolic transvalvular flow and proximal aortic wall changes in bicuspid aortic valve stenosis. Eur J Cardiothorac Surg 46(2):234\u2013239. discussion 239","journal-title":"European Journal of Cardio-Thoracic Surgery"},{"issue":"4","key":"1632_CR4","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1161\/CIRCIMAGING.112.973370","volume":"5","author":"AJ Barker","year":"2012","unstructured":"Barker AJ, Markl M, Burk J et al (2012) Bicuspid aortic valve is associated with altered wall shear stress in the ascending aorta. Circ Cardiovasc Imaging 5(4):457\u2013466","journal-title":"Circ Cardiovasc Imaging"},{"issue":"19","key":"1632_CR5","doi-asserted-by":"publisher","first-page":"2106","DOI":"10.1016\/j.jacc.2018.02.075","volume":"71","author":"F Vincent","year":"2018","unstructured":"Vincent F, Rauch A, Loobuyck V et al (2018) Arterial pulsatility and circulating von willebrand factor in patients on mechanical circulatory support. J Am Coll Cardiol 71(19):2106\u20132118","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"1632_CR6","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1159\/000091648","volume":"43","author":"RS Reneman","year":"2006","unstructured":"Reneman RS, Arts T, Hoeks AP (2006) Wall shear stress\u2013an important determinant of endothelial cell function and structure\u2014in the arterial system in vivo. Discrepancies with theory. J Vasc Res 43(3):251\u2013269","journal-title":"Discrepancies with theory. J Vasc Res"},{"issue":"8","key":"1632_CR7","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1016\/j.jacc.2015.06.1310","volume":"66","author":"DG Guzzardi","year":"2015","unstructured":"Guzzardi DG, Barker AJ, van Ooij P et al (2015) Valve-related hemodynamics mediate human bicuspid aortopathy: insights from wall shear stress mapping. J Am Coll Cardiol 66(8):892\u2013900","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"1632_CR8","doi-asserted-by":"publisher","first-page":"2112-2120.e2","DOI":"10.1016\/j.jtcvs.2018.05.095","volume":"156","author":"Emilie Bollache","year":"2018","unstructured":"Bollache E, Guzzardi DG, Sattari S, et al (2018) Aortic valve-mediated wall shear stress is heterogeneous and predicts regional aortic elastic fiber thinning in bicuspid aortic valve-associated aortopathy. J Thorac Cardiovasc Surg 156(6):2112\u20132120 e2112","journal-title":"The Journal of Thoracic and Cardiovascular Surgery"},{"key":"1632_CR9","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1532-429X-12-4","volume":"12","author":"PM den Reijer","year":"2010","unstructured":"den Reijer PM, Sallee D, van der Velden P et al (2010) Hemodynamic predictors of aortic dilatation in bicuspid aortic valve by velocity-encoded cardiovascular magnetic resonance. J Cardiovasc Magn Reson 12:4","journal-title":"J Cardiovasc Magn Reson"},{"issue":"6","key":"1632_CR10","doi-asserted-by":"publisher","first-page":"1749-1757.e1","DOI":"10.1016\/j.jtcvs.2014.01.021","volume":"147","author":"Alessandro Della Corte","year":"2014","unstructured":"Della Corte A, Body SC, Booher AM, et al (2014) Surgical treatment of bicuspid aortic valve disease: knowledge gaps and research perspectives. J Thorac Cardiovasc Surg 147(6):1749\u20131757, 1757 e1741","journal-title":"The Journal of Thoracic and Cardiovascular Surgery"},{"issue":"12","key":"1632_CR11","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1016\/j.jcmg.2013.07.009","volume":"6","author":"A Della Corte","year":"2013","unstructured":"Della Corte A, Bancone C, Buonocore M et al (2013) Pattern of ascending aortic dimensions predicts the growth rate of the aorta in patients with bicuspid aortic valve. JACC Cardiovasc Imaging 6(12):1301\u20131310","journal-title":"JACC Cardiovasc Imaging"},{"key":"1632_CR12","doi-asserted-by":"crossref","unstructured":"Cheung K, Boodhwani M, Chan KL, Beauchesne L, Dick A, Coutinho T (2017) Thoracic aortic aneurysm growth: role of sex and aneurysm etiology. J Am Heart Assoc 6(2):e003792","DOI":"10.1161\/JAHA.116.003792"},{"issue":"1","key":"1632_CR13","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1002\/jmri.24362","volume":"40","author":"MD Hope","year":"2014","unstructured":"Hope MD, Sigovan M, Wrenn SJ, Saloner D, Dyverfeldt P (2014) MRI hemodynamic markers of progressive bicuspid aortic valve-related aortic disease. J Magn Reson Imaging 40(1):140\u2013145","journal-title":"J Magn Reson Imaging"},{"issue":"4","key":"1632_CR14","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1002\/jmri.20871","volume":"25","author":"M Markl","year":"2007","unstructured":"Markl M, Harloff A, Bley TA et al (2007) Time-resolved 3D MR velocity mapping at 3T: improved navigator-gated assessment of vascular anatomy and blood flow. J Magn Reson Imaging 25(4):824\u2013831","journal-title":"J Magn Reson Imaging"},{"issue":"1","key":"1632_CR15","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1097\/RCT.0000000000000312","volume":"40","author":"S Schnell","year":"2016","unstructured":"Schnell S, Entezari P, Mahadewia RJ et al (2016) improved semiautomated 4D Flow MRI analysis in the aorta in patients with congenital aortic valve anomalies versus tricuspid aortic valves. J Comput Assist Tomogr 40(1):102\u2013108","journal-title":"J Comput Assist Tomogr"},{"issue":"6","key":"1632_CR16","doi-asserted-by":"publisher","first-page":"1673","DOI":"10.1002\/jmri.25305","volume":"44","author":"MJ Rose","year":"2016","unstructured":"Rose MJ, Jarvis K, Chowdhary V et al (2016) Efficient method for volumetric assessment of peak blood flow velocity using 4D flow MRI. J Magn Reson Imaging 44(6):1673\u20131682","journal-title":"J Magn Reson Imaging"},{"issue":"2","key":"1632_CR17","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1002\/jmri.24560","volume":"41","author":"WV Potters","year":"2015","unstructured":"Potters WV, van Ooij P, Marquering H, vanBavel E, Nederveen AJ (2015) Volumetric arterial wall shear stress calculation based on cine phase contrast MRI. J Magn Reson Imaging 41(2):505\u2013516","journal-title":"J Magn Reson Imaging"},{"issue":"5","key":"1632_CR18","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1016\/j.jtcvs.2007.01.039","volume":"133","author":"HH Sievers","year":"2007","unstructured":"Sievers HH, Schmidtke C (2007) A classification system for the bicuspid aortic valve from 304 surgical specimens. J Thorac Cardiovasc Surg 133(5):1226\u20131233","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1632_CR19","unstructured":"Nishimura RA, Otto CM, Bonow RO, et al. (2014) AHA\/ACC guideline for the management of patients with valvular heart disease. A report of the American College of Cardiology\/American Heart Association task force on practice guidelines. J Am Coll Cardiol 63:e57\u2013e185"},{"issue":"23","key":"1632_CR20","doi-asserted-by":"publisher","first-page":"2440","DOI":"10.1161\/CIR.0000000000000029","volume":"129","author":"RA Nishimura","year":"2014","unstructured":"Nishimura RA, Otto CM, Bonow RO et al (2014) AHA\/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology\/American Heart Association task force on practice guidelines. Circulation 129(23):2440\u20132492","journal-title":"Circulation"},{"issue":"3","key":"1632_CR21","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1161\/CIRCULATIONAHA.107.742486","volume":"119","author":"PJ Cawley","year":"2009","unstructured":"Cawley PJ, Maki JH, Otto CM (2009) Cardiovascular magnetic resonance imaging for valvular heart disease: technique and validation. Circulation 119(3):468\u2013478","journal-title":"Circulation"},{"issue":"2","key":"1632_CR22","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1161\/CIRCIMAGING.108.768911","volume":"1","author":"ED Burman","year":"2008","unstructured":"Burman ED, Keegan J, Kilner PJ (2008) Aortic root measurement by cardiovascular magnetic resonance: specification of planes and lines of measurement and corresponding normal values. Circ Cardiovasc Imaging 1(2):104\u2013113","journal-title":"Circ Cardiovasc Imaging"},{"issue":"4","key":"1632_CR23","doi-asserted-by":"publisher","first-page":"S52-S62.e3","DOI":"10.1016\/j.jtcvs.2016.12.033","volume":"153","author":"Naoyuki Kimura","year":"2017","unstructured":"Kimura N, Nakamura M, Komiya K, et al (2017) Patient-specific assessment of hemodynamics by computational fluid dynamics in patients with bicuspid aortopathy. J Thorac Cardiovasc Surg 153(4):S52\u2013S62","journal-title":"The Journal of Thoracic and Cardiovascular Surgery"},{"issue":"10","key":"1632_CR24","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1001\/jama.2011.1286","volume":"306","author":"HI Michelena","year":"2011","unstructured":"Michelena HI, Khanna AD, Mahoney D et al (2011) Incidence of aortic complications in patients with bicuspid aortic valves. JAMA 306(10):1104\u20131112","journal-title":"JAMA"},{"issue":"21","key":"1632_CR25","doi-asserted-by":"publisher","first-page":"2776","DOI":"10.1161\/CIRCULATIONAHA.107.740878","volume":"117","author":"HI Michelena","year":"2008","unstructured":"Michelena HI, Desjardins VA, Avierinos JF et al (2008) Natural history of asymptomatic patients with normally functioning or minimally dysfunctional bicuspid aortic valve in the community. Circulation 117(21):2776\u20132784","journal-title":"Circulation"},{"issue":"4","key":"1632_CR26","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.jacc.2012.01.072","volume":"60","author":"MD Hope","year":"2012","unstructured":"Hope MD, Wrenn J, Sigovan M, Foster E, Tseng EE, Saloner D (2012) Imaging biomarkers of aortic disease: increased growth rates with eccentric systolic flow. J Am Coll Cardiol 60(4):356\u2013357","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"1632_CR27","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1016\/j.jcmg.2011.05.004","volume":"4","author":"MD Hope","year":"2011","unstructured":"Hope MD, Hope TA, Crook SE et al (2011) 4D flow CMR in assessment of valve-related ascending aortic disease. JACC Cardiovasc Imaging 4(7):781\u2013787","journal-title":"JACC Cardiovasc Imaging"},{"issue":"3","key":"1632_CR28","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/j.ijcard.2013.11.034","volume":"170","author":"F von Knobelsdorff-Brenkenhoff","year":"2014","unstructured":"von Knobelsdorff-Brenkenhoff F, Trauzeddel RF, Barker AJ, Gruettner H, Markl M, Schulz-Menger J (2014) Blood flow characteristics in the ascending aorta after aortic valve replacement\u2013a pilot study using 4D-flow MRI. Int J Cardiol 170(3):426\u2013433","journal-title":"Int J Cardiol"},{"issue":"3","key":"1632_CR29","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1002\/mrm.25224","volume":"73","author":"P van Ooij","year":"2015","unstructured":"van Ooij P, Potters WV, Nederveen AJ et al (2015) A methodology to detect abnormal relative wall shear stress on the full surface of the thoracic aorta using four-dimensional flow MRI. Magn Reson Med 73(3):1216\u20131227","journal-title":"Magn Reson Med"},{"key":"1632_CR30","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1186\/1532-429X-14-84","volume":"14","author":"J Burk","year":"2012","unstructured":"Burk J, Blanke P, Stankovic Z et al (2012) Evaluation of 3D blood flow patterns and wall shear stress in the normal and dilated thoracic aorta using flow-sensitive 4D CMR. J Cardiovasc Magn Reson 14:84","journal-title":"J Cardiovasc Magn Reson"},{"issue":"11","key":"1632_CR31","doi-asserted-by":"publisher","first-page":"2997","DOI":"10.1161\/STROKEAHA.108.521617","volume":"39","author":"L Boussel","year":"2008","unstructured":"Boussel L, Rayz V, McCulloch C et al (2008) Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study. Stroke 39(11):2997\u20133002","journal-title":"Stroke"},{"issue":"6","key":"1632_CR32","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1016\/j.athoracsur.2016.05.038","volume":"102","author":"MV Regeer","year":"2016","unstructured":"Regeer MV, Versteegh MI, Klautz RJ et al (2016) Effect of aortic valve replacement on aortic root dilatation rate in patients with bicuspid and Tricuspid Aortic valves. Ann Thorac Surg 102(6):1981\u20131987","journal-title":"Ann Thorac Surg"},{"issue":"2","key":"1632_CR33","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1136\/heartjnl-2013-304920","volume":"100","author":"D Detaint","year":"2014","unstructured":"Detaint D, Michelena HI, Nkomo VT, Vahanian A, Jondeau G, Sarano ME (2014) Aortic dilatation patterns and rates in adults with bicuspid aortic valves: a comparative study with Marfan syndrome and degenerative aortopathy. Heart 100(2):126\u2013134","journal-title":"Heart"},{"issue":"4","key":"1632_CR34","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1097\/RLI.0000000000000332","volume":"52","author":"Brian Trinh","year":"2017","unstructured":"Trinh B, Dubin I, Rahman O, et al (2016) Aortic volumetry at contrast-enhanced magnetic resonance angiography: feasibility as a sensitive method for monitoring bicuspid aortic valve aortopathy. Invest Radiol. \n                    https:\/\/doi.org\/10.1097\/RLI.0000000000000332","journal-title":"Investigative Radiology"},{"key":"1632_CR35","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/1532-429X-15-81","volume":"15","author":"U Truong","year":"2013","unstructured":"Truong U, Fonseca B, Dunning J et al (2013) Wall shear stress measured by phase contrast cardiovascular magnetic resonance in children and adolescents with pulmonary arterial hypertension. J Cardiovasc Magn Reson 15:81","journal-title":"J Cardiovasc Magn Reson"},{"issue":"2","key":"1632_CR36","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1002\/jmri.25956","volume":"48","author":"ES Farag","year":"2013","unstructured":"Farag ES, van Ooij P, Planken RN, et al (2018) Aortic valve stenosis and aortic diameters determine the extent of increased wall shear stress in bicuspid aortic valve disease. J Magn Reson Imaging 48(2):522\u2013530","journal-title":"J Magn Reson Imaging"},{"issue":"1","key":"1632_CR37","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1002\/jmri.24959","volume":"43","author":"P van Ooij","year":"2016","unstructured":"van Ooij P, Powell AL, Potters WV, Carr JC, Markl M, Barker AJ (2016) Reproducibility and interobserver variability of systolic blood flow velocity and 3D wall shear stress derived from 4D flow MRI in the healthy aorta. J Magn Reson Imaging 43(1):236\u2013248","journal-title":"J Magn Reson Imaging"},{"issue":"1","key":"1632_CR38","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1002\/jmri.23793","volume":"37","author":"S Nordmeyer","year":"2013","unstructured":"Nordmeyer S, Riesenka E, Messroghli D et al (2013) Four-dimensional velocity-encoded magnetic resonance imaging improves blood flow quantification in patients with complex accelerated flow. J Magn Reson Imaging 37(1):208\u2013216","journal-title":"J Magn Reson Imaging"}],"container-title":["The International Journal of Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-019-01632-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10554-019-01632-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-019-01632-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T23:13:44Z","timestamp":1590621224000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10554-019-01632-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,29]]},"references-count":38,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["1632"],"URL":"https:\/\/doi.org\/10.1007\/s10554-019-01632-7","relation":{},"ISSN":["1569-5794","1573-0743"],"issn-type":[{"value":"1569-5794","type":"print"},{"value":"1573-0743","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,29]]},"assertion":[{"value":"5 January 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors report the following conflicts of interest: Michael Markl: Research support by Siemens Healthineers, Research Grant: by Cryolife Inc, Consultant and Research Grant by Circle - Cardiovascular Imaging.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}