{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:40:08Z","timestamp":1793814008472,"version":"4.6.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T00:00:00Z","timestamp":1629936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T00:00:00Z","timestamp":1629936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e0 degli Studi di Roma La Sapienza"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Cardiovasc Imaging"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To assess the impact of regurgitant jet direction on left ventricular function and intraventricular hemodynamics in asymptomatic patients with bicuspid aortic valve (BAV) and mild aortic valve regurgitation (AR), using cardiac magnetic resonance (CMR) feature tracking and 4D flow imaging.\u00a0Fifty BAV individuals were retrospectively selected: 15 with mild AR and posterior regurgitation jet (Group-PJ), 15 with regurgitant jet in other directions (Group-nPJ) and 20 with no regurgitation (Controls). CMR protocol included cine steady state free precession (SSFP) sequences and 4D Flow imaging covering the entire left ventricle (LV) cavity and the aortic root. Cine-SSFP images were analyzed to assess LV volumes, longitudinal and circumferential myocardial strain.\u00a0Circumferential and longitudinal peak diastolic strain rate (PDSR) and peak diastolic velocity (PDV) were reduced in group PJ if compared to group nPJ and control group (PDSR\u2009=\u20091.10\u2009\u00b1\u20090.2\u00a01\/s vs. 1.34\u2009\u00b1\u20090.5\u00a01\/s vs. 1.53\u2009\u00b1\u20090.3\u00a01\/s, p:0.001 and 0.68\u2009\u00b1\u20090.2\u00a01\/s vs. 1.17\u2009\u00b1\u20090.2\u00a01\/s vs. 1.05\u2009\u00b1\u20090.4\u00a01\/s ; p\u2009&lt;\u20090.001, PDV = \u2212\u00a0101.6\u2009\u00b1\u200928.1\u00a0deg\/s vs. \u2212\u00a0201.4\u2009\u00b1\u200985.9\u00a0deg\/s vs. \u2212\u2009221.6\u2009\u00b1\u200967.1\u00a0deg\/s; p\u2009&lt;\u20090.001 and \u2212\u200928.1\u2009\u00b1\u20098 mm\/s vs. \u2212\u00a038.9\u2009\u00b1\u200911.1 mm\/s vs. \u2212\u00a043.6\u2009\u00b1\u200914.3 mm\/s, p\u2009&lt;\u20090.001, respectively), whereas no differences have been found in systolic strain values. 4D Flow images (available only in 9 patients) showed deformation of diastolic transmitral streamlines direction in group PJ compared to other groups.\u00a0In BAV patients with mild AR, the posterior direction of the regurgitant jet may hamper the complete mitral valve opening, disturbing transmitral flow and slowing the LV diastolic filling.<\/jats:p>","DOI":"10.1007\/s10554-021-02384-z","type":"journal-article","created":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T21:02:39Z","timestamp":1630011759000},"page":"211-221","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Impaction of regurgitation jet on anterior mitral leaflet is associated with diastolic dysfunction in patients with bicuspid aortic valve and mild insufficiency: a cardiovascular magnetic resonance study"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4708-5120","authenticated-orcid":false,"given":"Nicola","family":"Galea","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Pambianchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Cundari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Sturla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia","family":"Marchitelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Putotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Versacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruggero","family":"De Paulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Francone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Catalano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,26]]},"reference":[{"issue":"25","key":"2384_CR1","doi-asserted-by":"publisher","first-page":"2789","DOI":"10.1016\/j.jacc.2009.12.068","volume":"55","author":"SC Siu","year":"2010","unstructured":"Siu SC, Silversides CK (2010) Bicuspid aortic valve disease. J Am Coll Cardiol 55(25):2789\u20132800. doi:https:\/\/doi.org\/10.1016\/j.jacc.2009.12.068","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"2384_CR2","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1016\/j.jtcvs.2007.01.039","volume":"133","author":"HH Sievers","year":"2007","unstructured":"Sievers HH, Schmidtke C (2007) A classification system for the bicuspid aortic valve from 304 surgical specimens. J Thorac Cardiovasc Surg 133(5):1226\u20131233. doi:https:\/\/doi.org\/10.1016\/j.jtcvs.2007.01.039","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"1","key":"2384_CR3","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.athoracsur.2016.05.085","volume":"103","author":"E Girdauskas","year":"2017","unstructured":"Girdauskas E, Rouman M, Disha K, Fey B, Dubslaff G, von Kodolitsch Y, Reichenspurner H, Borger MA, Kuntze T (2017) Morphologic and Functional Markers of Aortopathy in Patients With Bicuspid Aortic Valve Insufficiency Versus Stenosis. Ann Thorac Surg 103(1):49\u201357. doi:https:\/\/doi.org\/10.1016\/j.athoracsur.2016.05.085","journal-title":"Ann Thorac Surg"},{"issue":"3","key":"2384_CR4","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1536\/ihj.18-363","volume":"60","author":"X Ren","year":"2019","unstructured":"Ren X, Li F, Wang C, Hou Z, Gao Y, Yin W, Lu B (2019) Age- and Sex-Related Aortic Valve Dysfunction and Aortopathy Difference in Patients with Bicuspid Aortic Valve. Int Heart J 60(3):637\u2013642. doi:https:\/\/doi.org\/10.1536\/ihj.18-363","journal-title":"Int Heart J"},{"issue":"12","key":"2384_CR5","doi-asserted-by":"publisher","first-page":"2104","DOI":"10.1016\/j.amjcard.2018.08.063","volume":"122","author":"WC Roberts","year":"2018","unstructured":"Roberts WC, McCullough SP, Vasudevan A (2018) Characteristics of Adults Having Aortic Valve Replacement for Pure Aortic Regurgitation Involving a Congenitally Bicuspid Aortic Valve Unaffected by Infective Endocarditis or Aortic Dissection. Am J Cardiol 122(12):2104\u20132111. doi:https:\/\/doi.org\/10.1016\/j.amjcard.2018.08.063","journal-title":"Am J Cardiol"},{"issue":"12","key":"2384_CR6","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1016\/s0025-6196(12)65618-3","volume":"59","author":"LJ Olson","year":"1984","unstructured":"Olson LJ, Subramanian R, Edwards WD (1984) Surgical pathology of pure aortic insufficiency: a study of 225 cases. Mayo Clin Proc 59(12):835\u2013841. doi:https:\/\/doi.org\/10.1016\/s0025-6196(12)65618-3","journal-title":"Mayo Clin Proc"},{"issue":"1","key":"2384_CR7","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.athoracsur.2018.03.034","volume":"106","author":"W Ma","year":"2018","unstructured":"Ma W, Zhang W, Shi W, Kong Y, Ma X (2018) Left Ventricular Diastolic Function After Aortic Valve Replacement for Chronic Aortic Regurgitation. Ann Thorac Surg 106(1):24\u201329. doi:https:\/\/doi.org\/10.1016\/j.athoracsur.2018.03.034","journal-title":"Ann Thorac Surg"},{"issue":"8","key":"2384_CR8","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/j.cpcardiol.2017.10.004","volume":"43","author":"OA Akinseye","year":"2018","unstructured":"Akinseye OA, Pathak A, Ibebuogu UN (2018) Aortic Valve Regurgitation: A Comprehensive Review. Curr Probl Cardiol 43(8):315\u2013334. doi:https:\/\/doi.org\/10.1016\/j.cpcardiol.2017.10.004","journal-title":"Curr Probl Cardiol"},{"issue":"1","key":"2384_CR9","doi-asserted-by":"publisher","first-page":"8884","DOI":"10.1038\/s41598-017-09252-8","volume":"7","author":"K Hirasawa","year":"2017","unstructured":"Hirasawa K, Izumo M, Sasaoka T, Ashikaga T, Suzuki K, Harada T, Isobe M, Akashi YJ (2017) Effect of aortic regurgitant jet direction on mitral valve leaflet remodeling: a real-time three-dimensional transesophageal echocardiography study. Sci Rep 7(1):8884. doi:https:\/\/doi.org\/10.1038\/s41598-017-09252-8","journal-title":"Sci Rep"},{"issue":"4","key":"2384_CR10","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1161\/01.cir.67.4.860","volume":"67","author":"S Nakao","year":"1983","unstructured":"Nakao S, Tanaka H, Tahara M, Yoshimura H, Sakurai S, Tei C, Kashima T (1983) A regurgitant jet and echocardiographic abnormalities in aortic regurgitation: an experimental study. Circulation 67(4):860\u2013865. doi:https:\/\/doi.org\/10.1161\/01.cir.67.4.860","journal-title":"Circulation"},{"issue":"5","key":"2384_CR11","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1097\/HCO.0000000000000538","volume":"33","author":"ACT Ng","year":"2018","unstructured":"Ng ACT, Delgado V, Bax JJ (2018) Application of left ventricular strain in patients with aortic and mitral valve disease. Curr Opin Cardiol 33(5):470\u2013478. doi:https:\/\/doi.org\/10.1097\/HCO.0000000000000538","journal-title":"Curr Opin Cardiol"},{"issue":"1 Pt 2","key":"2384_CR12","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.jcmg.2019.02.031","volume":"13","author":"MA Chamsi-Pasha","year":"2020","unstructured":"Chamsi-Pasha MA, Zhan Y, Debs D, Shah DJ (2020) CMR in the Evaluation of Diastolic Dysfunction and Phenotyping of HFpEF: Current Role and Future Perspectives. JACC Cardiovasc Imaging 13(1 Pt 2):283\u2013296. doi:https:\/\/doi.org\/10.1016\/j.jcmg.2019.02.031","journal-title":"JACC Cardiovasc Imaging"},{"issue":"2","key":"2384_CR13","doi-asserted-by":"publisher","first-page":"284","DOI":"10.5935\/abc.20190193","volume":"114","author":"SM Ribeiro","year":"2020","unstructured":"Ribeiro SM, Azevedo Filho CF, Sampaio R, Tarasoutchi F, Grinberg M, Kalil-Filho R, Rochitte CE (2020) Longitudinal Shortening of the Left Ventricle by Cine-CMR for Assessment of Diastolic Function in Patients with Aortic Valve Disease. Arq Bras Cardiol 114(2):284\u2013292. doi:https:\/\/doi.org\/10.5935\/abc.20190193","journal-title":"Arq Bras Cardiol"},{"issue":"1","key":"2384_CR14","doi-asserted-by":"publisher","first-page":"26","DOI":"10.18383\/j.tom.2018.00005","volume":"4","author":"NS Burris","year":"2018","unstructured":"Burris NS, Lima APS, Hope MD, Ordovas KG (2018) Feature Tracking Cardiac MRI Reveals Abnormalities in Ventricular Function in Patients With Bicuspid Aortic Valve and Preserved Ejection Fraction. Tomography 4(1):26\u201332. doi:https:\/\/doi.org\/10.18383\/j.tom.2018.00005","journal-title":"Tomography"},{"issue":"4","key":"2384_CR15","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1093\/ehjci\/jex069","volume":"19","author":"M Schafer","year":"2018","unstructured":"Schafer M, Humphries S, Stenmark KR, Kheyfets VO, Buckner JK, Hunter KS, Fenster BE (2018) 4D-flow cardiac magnetic resonance-derived vorticity is sensitive marker of left ventricular diastolic dysfunction in patients with mild-to-moderate chronic obstructive pulmonary disease. Eur Heart J Cardiovasc Imaging 19(4):415\u2013424. doi:https:\/\/doi.org\/10.1093\/ehjci\/jex069","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2384_CR16","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1532-429X-15-35","volume":"15","author":"J Schulz-Menger","year":"2013","unstructured":"Schulz-Menger J, Bluemke DA, Bremerich J, Flamm SD, Fogel MA, Friedrich MG, Kim RJ, von Knobelsdorff-Brenkenhoff F, Kramer CM, Pennell DJ, Plein S, Nagel E (2013) Standardized image interpretation and post processing in cardiovascular magnetic resonance: Society for Cardiovascular Magnetic Resonance (SCMR) board of trustees task force on standardized post processing. J Cardiovasc Magn Reson 15:35. doi:https:\/\/doi.org\/10.1186\/1532-429X-15-35","journal-title":"J Cardiovasc Magn Reson"},{"issue":"8","key":"2384_CR17","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1093\/ehjci\/jev006","volume":"16","author":"RJ Taylor","year":"2015","unstructured":"Taylor RJ, Moody WE, Umar F, Edwards NC, Taylor TJ, Stegemann B, Townend JN, Hor KN, Steeds RP, Mazur W, Leyva F (2015) Myocardial strain measurement with feature-tracking cardiovascular magnetic resonance: normal values. Eur Heart J Cardiovasc Imaging 16(8):871\u2013881. doi:https:\/\/doi.org\/10.1093\/ehjci\/jev006","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"1","key":"2384_CR18","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s12968-015-0123-3","volume":"10","author":"F Andre","year":"2015","unstructured":"Andre F, Steen H, Matheis P, Westkott M, Breuninger K, Sander Y, Kammerer R, Galuschky C, Giannitsis E, Korosoglou G, Katus HA, Buss SJ (2015) Age- and gender-related normal left ventricular deformation assessed by cardiovascular magnetic resonance feature tracking. J Cardiovasc Magn Reson 10(1):25. doi:https:\/\/doi.org\/10.1186\/s12968-015-0123-3. 17 ) .","journal-title":"J Cardiovasc Magn Reson"},{"issue":"4","key":"2384_CR19","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1007\/s10554-018-1492-0","volume":"35","author":"Y Shang","year":"2019","unstructured":"Shang Y, Zhang X, Leng W, Lei X, Chen L, Zhou X, Chow K, Shi Y, Dong J, Liang Z, Wang J (2019) Increased fractal dimension of left ventricular trabeculations is associated with subclinical diastolic dysfunction in patients with type-2 diabetes mellitus. Int J Cardiovasc Imaging 35(4):665\u2013673. doi:https:\/\/doi.org\/10.1007\/s10554-018-1492-0","journal-title":"Int J Cardiovasc Imaging"},{"key":"2384_CR20","doi-asserted-by":"publisher","first-page":"99","DOI":"10.21037\/jovs.2018.04.16","volume":"4","author":"K De Brabandere","year":"2018","unstructured":"De Brabandere K, Voigt JU, Rex S, Meuris B, Verbrugghe P (2018) Aortic and mitral valve repair for anterior mitral leaflet perforation caused by severe aortic regurgitation. J Vis Surg 4:99. doi:https:\/\/doi.org\/10.21037\/jovs.2018.04.16","journal-title":"J Vis Surg"},{"issue":"2","key":"2384_CR21","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1148\/radiol.2020200195","volume":"296","author":"AA Kammerlander","year":"2020","unstructured":"Kammerlander AA, Dona C, Nitsche C, Koschutnik M, Schonbauer R, Duca F, Zotter-Tufaro C, Binder C, Aschauer S, Beitzke D, Loewe C, Hengstenberg C, Bonderman D, Mascherbauer J (2020) Feature Tracking of Global Longitudinal Strain by Using Cardiovascular MRI Improves Risk Stratification in Heart Failure with Preserved Ejection Fraction. Radiology 296(2):290\u2013298. doi:https:\/\/doi.org\/10.1148\/radiol.2020200195","journal-title":"Radiology"},{"issue":"4","key":"2384_CR22","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1093\/ejcts\/ezz109","volume":"56","author":"T Ikeda","year":"2019","unstructured":"Ikeda T, Iida M, Yokoyama N, Shimokawa T (2019) Mitral valve perforation due to coexisting severe aortic regurgitation. Eur J Cardiothorac Surg 56(4):815. doi:https:\/\/doi.org\/10.1093\/ejcts\/ezz109","journal-title":"Eur J Cardiothorac Surg"},{"issue":"Suppl D","key":"2384_CR23","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1093\/eurheartj\/15.suppl_d.2","volume":"15","author":"M Federmann","year":"1994","unstructured":"Federmann M, Hess OM (1994) Differentiation between systolic and diastolic dysfunction. Eur Heart J 15(Suppl D):2\u20136. https:\/\/doi.org\/10.1093\/eurheartj\/15.suppl_d.2","journal-title":"Eur Heart J"},{"issue":"2","key":"2384_CR24","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.echo.2018.11.011","volume":"32","author":"JJ Silbiger","year":"2019","unstructured":"Silbiger JJ (2019) Pathophysiology and Echocardiographic Diagnosis of Left Ventricular Diastolic Dysfunction. J Am Soc Echocardiogr 32(2):216\u2013232 e212. doi:https:\/\/doi.org\/10.1016\/j.echo.2018.11.011","journal-title":"J Am Soc Echocardiogr"},{"issue":"11","key":"2384_CR25","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.repc.2019.03.007","volume":"38","author":"R Ladeiras-Lopes","year":"2019","unstructured":"Ladeiras-Lopes R, Araujo M, Sampaio F, Leite-Moreira A, Fontes-Carvalho R (2019) The impact of diastolic dysfunction as a predictor of cardiovascular events: A systematic review and meta-analysis. Rev Port Cardiol 38(11):789\u2013804. doi:https:\/\/doi.org\/10.1016\/j.repc.2019.03.007","journal-title":"Rev Port Cardiol"},{"issue":"8","key":"2384_CR26","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1080\/14779072.2018.1497485","volume":"16","author":"GD Plitt","year":"2018","unstructured":"Plitt GD, Spring JT, Moulton MJ, Agrawal DK (2018) Mechanisms, diagnosis, and treatment of heart failure with preserved ejection fraction and diastolic dysfunction. Expert Rev Cardiovasc Ther 16(8):579\u2013589. doi:https:\/\/doi.org\/10.1080\/14779072.2018.1497485","journal-title":"Expert Rev Cardiovasc Ther"},{"issue":"3","key":"2384_CR27","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1017\/S1047951116002560","volume":"27","author":"I Rodrigues","year":"2017","unstructured":"Rodrigues I, Agapito AF, de Sousa L, Oliveira JA, Branco LM, Galrinho A, Abreu J, Timoteo AT, Rosa SA, Ferreira RC (2017) Bicuspid aortic valve outcomes. Cardiol Young 27(3):518\u2013529. doi:https:\/\/doi.org\/10.1017\/S1047951116002560","journal-title":"Cardiol Young"},{"issue":"4","key":"2384_CR28","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1093\/ehjci\/jet189","volume":"15","author":"B Ambale-Venkatesh","year":"2014","unstructured":"Ambale-Venkatesh B, Armstrong AC, Liu CY, Donekal S, Yoneyama K, Wu CO, Gomes AS, Hundley GW, Bluemke DA, Lima JA (2014) Diastolic function assessed from tagged MRI predicts heart failure and atrial fibrillation over an 8-year follow-up period: the multi-ethnic study of atherosclerosis. Eur Heart J Cardiovasc Imaging 15(4):442\u2013449. doi:https:\/\/doi.org\/10.1093\/ehjci\/jet189","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"1","key":"2384_CR29","doi-asserted-by":"publisher","first-page":"78.e19","DOI":"10.1016\/j.crad.2020.08.019","volume":"76","author":"ZL Li","year":"2021","unstructured":"Li ZL, He S, Xia CC, Peng WL, Li L, Liu KL, Zhang JG, Pu J, Guo YK (2021) Global longitudinal diastolic strain rate as a novel marker for predicting adverse outcomes in hypertrophic cardiomyopathy by cardiac magnetic resonance tissue tracking. Clin Radiol 76(1):78.e19-78.e25. https:\/\/doi.org\/10.1016\/j.crad.2020.08.019","journal-title":"Clin Radiol"},{"issue":"5","key":"2384_CR30","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1007\/s10439-017-1790-z","volume":"45","author":"I Okafor","year":"2017","unstructured":"Okafor I, Raghav V, Condado JF, Midha PA, Kumar G, Yoganathan AP (2017) Aortic Regurgitation Generates a Kinematic Obstruction Which Hinders Left Ventricular Filling. Ann Biomed Eng 45(5):1305\u20131314. doi:https:\/\/doi.org\/10.1007\/s10439-017-1790-z","journal-title":"Ann Biomed Eng"},{"key":"2384_CR31","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.jbiomech.2018.07.023","volume":"78","author":"G Di Labbio","year":"2018","unstructured":"Di Labbio G, Kadem L (2018) Jet collisions and vortex reversal in the human left ventricle. J Biomech 78:155\u2013160. doi:https:\/\/doi.org\/10.1016\/j.jbiomech.2018.07.023","journal-title":"J Biomech"},{"issue":"5","key":"2384_CR32","doi-asserted-by":"publisher","first-page":"e72","DOI":"10.1161\/CIR.0000000000000923","volume":"143","author":"CM Otto","year":"2021","unstructured":"Otto CM, Nishimura RA, Bonow RO, Carabello BA, Erwin JP III, Gentile F, Jneid H, Krieger EV, Mack M, McLeod C, O\u2019Gara PT, Rigolin VH, Sundt TM III, Thompson A, Toly C (2021) 2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice guidelines. Circulation 143(5):e72\u2013e227. https:\/\/doi.org\/10.1161\/CIR.0000000000000923","journal-title":"Circulation"},{"issue":"4","key":"2384_CR33","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1136\/bjsm.2008.047407","volume":"44","author":"G Galanti","year":"2010","unstructured":"Galanti G, Stefani L, Toncelli L, Vono MC, Mercuri R, Maffulli N (2010) Effects of sports activity in athletes with bicuspid aortic valve and mild aortic regurgitation. Br J Sports Med 44(4):275\u2013279. doi:https:\/\/doi.org\/10.1136\/bjsm.2008.047407","journal-title":"Br J Sports Med"},{"issue":"7","key":"2384_CR34","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.3390\/diagnostics11071282","volume":"11","author":"AS Bojer","year":"2021","unstructured":"Bojer AS, Soerensen MH, Gaede P, Myerson S, Madsen PL (2021) Left Ventricular Diastolic Function Studied with Magnetic Resonance Imaging: A Systematic Review of Techniques and Relation to Established Measures of Diastolic Function. Diagnostics (Basel) 11(7):1282. doi:https:\/\/doi.org\/10.3390\/diagnostics11071282","journal-title":"Diagnostics (Basel)"},{"issue":"1","key":"2384_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11897-018-0372-1","volume":"15","author":"J Webb","year":"2018","unstructured":"Webb J, Fovargue L, T\u00f8ndel K, Porter B, Sieniewicz B, Gould J, Rinaldi CA, Ismail T, Chiribiri A, Carr-White G (2018) The Emerging Role of Cardiac Magnetic Resonance Imaging in the Evaluation of Patients with HFpEF. Curr Heart Fail Rep 15(1):1\u20139. doi:https:\/\/doi.org\/10.1007\/s11897-018-0372-1","journal-title":"Curr Heart Fail Rep"}],"container-title":["The International Journal of Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-021-02384-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10554-021-02384-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-021-02384-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,6]],"date-time":"2022-02-06T18:03:25Z","timestamp":1644170605000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10554-021-02384-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,26]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["2384"],"URL":"https:\/\/doi.org\/10.1007\/s10554-021-02384-z","relation":{},"ISSN":["1569-5794","1573-0743"],"issn-type":[{"value":"1569-5794","type":"print"},{"value":"1573-0743","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,26]]},"assertion":[{"value":"13 May 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 August 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 August 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All the authors declare that they have no conflict of interest.\u00a0All authors have nothing to disclose for this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}