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A total of 63 patients who fulfilled our inclusion criteria were recruited into two groups according to thepresence or absence of persistent dyspnoea and exercise intolerance. Clinical, laboratory &amp; comprehensive echocardiographic examinations were done for all. We observed that 31.7% of the previously healthy individuals developed dyspnoea &amp; exercise intolerance post-COVID-19 infection. There were significantly impaired LAS parameters in the symptomatic group (LA reservoir, contraction &amp; conduit strain, 22.7%, -6.6% &amp; -16.1% versus 40%, -12%, and ? 27% in the asymptomatic group with P &lt; 0.000). Only LA reservoir strain and LA stiffness can independently predict the development of dyspnoea &amp; exercise intolerance post-COVID-19 at cut-off values of 30% &amp; 24.5% respectively with a sensitivity of 90% and a specificity of 91%, P &lt; 0.001. These impaired LAS parameters could explain the developed symptoms post-COVID-19 recovery, even before disturbed conventional diastolic echocardiographic parameters.LAS parameters are significantly associated with the developed exertional dyspnoea &amp; exercise intolerance post-COVID-19. LA reservoir strain &amp; LA stiffness could provide a simple, easily available tool that points to early LV diastolic dysfunction and may direct the therapy in this subset of the population.<\/jats:p>","DOI":"10.1007\/s10554-023-02801-5","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T06:03:46Z","timestamp":1676613826000},"page":"939-944","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Left atrial longitudinal strain analysis in long Covid-19 syndrome"],"prefix":"10.1007","volume":"39","author":[{"given":"Shimaa Gamal","family":"ZeinElabdeen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelsalam","family":"Sherif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nader Talaat","family":"Kandil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdalaali Mohammed Omar","family":"Altabib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud Abdelaziz","family":"abdelrashid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,14]]},"reference":[{"key":"2801_CR1","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1001\/jama.2020.12603","volume":"324","author":"A Carf\u00ec","year":"2020","unstructured":"Carf\u00ec A, Bernabei R, Landi F (2020) Group for the GAC-19 P-ACS. 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