{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T01:44:06Z","timestamp":1774316646355,"version":"3.50.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Cardiovasc Imaging"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Ascending aortic (AoAsc) dilatation can lead to acute aortic syndromes and has been described in various familial cardiac diseases. Its prevalence and clinical significance in patients with noncompaction cardiomyopathy (NCCM) are however unknown. Establishing the prevalence can facilitate recommendations on routine screening in NCCM. In this cross-sectional cohort study based on the Rijnmond Heart Failure\/Cardiomyopathy Registry, the patient were enrolment between 2014 and 2021. All NCCM patients (n\u2009=\u2009109) were age and sex matched with 109 dilated cardiomyopathy (DCM) patients as controls. The aortic diameters were measured through the parasternal long-axis transthoracic echocardiographic view at the sinuses of valsalva (SoV-Ao), sinotubular junction (STJ) and ascending aorta (AscAo). Dilatation was defined using published criteria adjusted for body surface area (BSA), sex, and age. Median age of age-sex matched NCCM and DCM patients was 45[31\u201356] vs. 45 [31\u201355] years with 53% males in both groups. NCCM patients had more familial hereditary patterns and genetic variants (55% vs. 24%, p\u2009&lt;\u20090.001). DCM patients had more heart failure and left ventricular dysfunction (ejection fraction 34\u2009\u00b1\u200911 vs. 41\u2009\u00b1\u200912, p\u2009=\u20090.001). Ascending aortic dilatation was present in 8(7%) patients with NCCM and 5(5%) patients with DCM (p\u2009=\u20090.46). All dilatations were classified as mild. In conclusion, in this cross-sectional cohort study the prevalence of ascending aortic dilatation in NCCM patients was 7%, which were only mild dilatations and not significantly different from an age-sex matched cohort of DCM patients. Routine aortic dilatation screening therefore does not seem warranted in patients with NCCM.<\/jats:p>","DOI":"10.1007\/s10554-023-02882-2","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T17:40:09Z","timestamp":1685554809000},"page":"1687-1695","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence and clinical correlates of ascending aortic dilatation in patients with noncompaction cardiomyopathy"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5423-4433","authenticated-orcid":false,"given":"Martijn","family":"Tukker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4143-4839","authenticated-orcid":false,"given":"Maarten J.G.","family":"Leening","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0323-5118","authenticated-orcid":false,"given":"Sharida","family":"Mohamedhoesein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0376-2628","authenticated-orcid":false,"given":"Alexander L.A.","family":"Vanmaele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7794-5991","authenticated-orcid":false,"given":"Kadir","family":"Caliskan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"key":"2882_CR1","doi-asserted-by":"publisher","unstructured":"Jenni R, Oechslin EN, van der Loo B (2007) \u201cIsolated ventricular non-compaction of the myocardium in adults,\u201d Heart, vol.\u00a093, no. 1, pp.\u00a011 \u2013 5, Jan https:\/\/doi.org\/10.1136\/hrt.2005.082271","DOI":"10.1136\/hrt.2005.082271"},{"key":"2882_CR2","doi-asserted-by":"publisher","unstructured":"Davies RR et al (Jan 2002) Yearly rupture or dissection rates for thoracic aortic aneurysms: simple prediction based on size. 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