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The aim of our study was to evaluate significance of right ventricular dysfunction in patients with severe aortic stenosis by modern 3D echocardiographic methods. This is prospective analysis of 68 patients with severe high and low-gradient aortic stenosis. We evaluated function of left and right ventricle on the basis of 3D reconstruction. Enddiastolic, endsystolic volumes, ejection fraction and stroke volumes of both chambers were assessed. There were more patients with right ventricular dysfunction in low-gradient group (RVEF\u2009&lt;\u200945%) than in the high-gradient group (63.6% vs 39%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.02). Low-gradient patients had worse right ventricular function than high-gradient patients (RVEF 36% vs 46%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.02). There wasn\u2019t any significant correlation between the right ventricular dysfunction and pulmonary hypertension (r\u2009=\u2009\u2212\u20090.25,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.036). There was significant correlation between left and right ejection fraction (r\u2009=\u20090.78,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001). Multiple regression analysis revealed that the only predictor of right ventricular function is the left ventricular function. According to our results we can state that right ventricular dysfunction is more common in patients with low-gradient than in high-gradient aortic stenosis and the only predictor of right ventricular dysfunction is left ventricular dysfunction, probably based on ventriculo-ventricular interaction. Pulmonary hypertension in patients with severe AS does not predict right ventricular dysfunction.\n                  <\/jats:p>","DOI":"10.1007\/s10554-023-02986-9","type":"journal-article","created":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T11:01:46Z","timestamp":1699700506000},"page":"299-305","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Aortic stenosis and right ventricular dysfunction"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8811-025X","authenticated-orcid":false,"given":"Pavol","family":"Fulop","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3458-3956","authenticated-orcid":false,"given":"Gabriel","family":"Valocik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9693-7137","authenticated-orcid":false,"given":"Marianna","family":"Barbierik Vachalcova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavol","family":"Zenuch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5500-8323","authenticated-orcid":false,"given":"Lenka","family":"Filipova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,11]]},"reference":[{"key":"2986_CR1","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1161\/CIRCULATIONAHA.119.041080","volume":"140","author":"B Lung","year":"2019","unstructured":"Lung B, Delgado V, Rosenhek R, Price S, Prendergast B, Wendler O et al (2019) Contemporary presentation and management of valvular heart disease: the EURObservational research programme valvular heart disease Ii survey. 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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}]}}