{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:20:52Z","timestamp":1791883252479,"version":"4.3.4"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T00:00:00Z","timestamp":1720396800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T00:00:00Z","timestamp":1720396800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Cardiovasc Imaging"],"DOI":"10.1007\/s10554-024-03179-8","type":"journal-article","created":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T13:02:00Z","timestamp":1720443720000},"page":"1617-1629","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Echocardiographic assessment of left ventricular mechanics in individuals with mitral valve prolapse: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"40","author":[{"given":"Andrea","family":"Sonaglioni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Fagiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Luigi","family":"Nicolosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Lombardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,8]]},"reference":[{"key":"3179_CR1","doi-asserted-by":"publisher","first-page":"2158","DOI":"10.1161\/CIRCULATIONAHA.113.006702","volume":"129","author":"FN Delling","year":"2014","unstructured":"Delling FN, Vasan RS (2014) Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis. Circulation 129:2158\u20132170","journal-title":"Circulation"},{"key":"3179_CR2","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1016\/0002-8703(87)90955-0","volume":"113","author":"RB Devereux","year":"1987","unstructured":"Devereux RB, Kramer-Fox R, Shear MK, Kligfield P, Pini R, Savage DD (1987) Diagnosis and classification of severity of mitral valve prolapse: methodologic, biologic, and prognostic considerations. Am Heart J 113:1265\u20131280","journal-title":"Am Heart J"},{"key":"3179_CR3","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/S0140-6736(05)17869-6","volume":"365","author":"E Hayek","year":"2005","unstructured":"Hayek E, Gring CN, Griffin BP (2005) Mitral valve prolapse. Lancet 365:507\u2013518","journal-title":"Lancet"},{"key":"3179_CR4","first-page":"3121","volume":"44","author":"B Essayagh","year":"2023","unstructured":"Essayagh B, Sabbag A, El-Am E, Cavalcante JL, Michelena HI, Enriquez-Sarano M (2023) Arrhythmic mitral valve prolapse and mitral annular disjunction: pathophysiology, risk stratification, and management. Eur Heart J 2023 44:3121\u20133135","journal-title":"Eur Heart J 2023"},{"key":"3179_CR5","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1093\/europace\/euac125","volume":"24","author":"A Sabbag","year":"2022","unstructured":"Sabbag A, Essayagh B, Barrera JDR et al (2022) EHRA expert consensus statement on arrhythmic mitral valve prolapse and mitral annular disjunction complex in collaboration with the ESC Council on valvular heart disease and the European Association of Cardiovascular Imaging endorsed cby the Heart Rhythm Society, by the Asia Pacific Heart Rhythm Society, and by the Latin American Heart Rhythm Society. Europace 24:1981\u20132003","journal-title":"Europace"},{"key":"3179_CR6","doi-asserted-by":"publisher","first-page":"2278","DOI":"10.1016\/j.jcmg.2019.06.021","volume":"12","author":"V Mantegazza","year":"2019","unstructured":"Mantegazza V, Tamborini G, Muratori M et al (2019) Mitral annular disjunction in a large cohort of patients with mitral valve prolapse and significant regurgitation. JACC Cardiovasc Imaging 12:2278\u20132280","journal-title":"JACC Cardiovasc Imaging"},{"key":"3179_CR7","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1111\/echo.14437","volume":"36","author":"S Bennett","year":"2019","unstructured":"Bennett S, Thamman R, Griffiths T et al (2019) Mitral annular disjunction: a systematic review of the literature. Echocardiography 36:1549\u20131558","journal-title":"Echocardiography"},{"key":"3179_CR8","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/j.jacc.2020.06.029","volume":"76","author":"B Essayagh","year":"2020","unstructured":"Essayagh B, Sabbag A, Antoine C et al (2020) Presentation and outcome of arrhythmic mitral valve prolapse. J Am Coll Cardiol 76:637\u2013649","journal-title":"J Am Coll Cardiol"},{"key":"3179_CR9","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1161\/CIRCULATIONAHA.116.025795","volume":"135","author":"MA Konstam","year":"2017","unstructured":"Konstam MA, Abboud FM (2017) Ejection fraction: Misunderstood and overrated (changing the paradigm in Categorizing Heart failure). Circulation 135:717\u2013719","journal-title":"Circulation"},{"key":"3179_CR10","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.jcmg.2017.11.017","volume":"11","author":"E Potter","year":"2018","unstructured":"Potter E, Marwick TH (2018) Assessment of Left ventricular function by Echocardiography: the case for routinely adding global longitudinal strain to Ejection Fraction. JACC Cardiovasc Imaging 11:260\u2013274","journal-title":"JACC Cardiovasc Imaging"},{"key":"3179_CR11","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1093\/ehjci\/jex244","volume":"18","author":"M Galderisi","year":"2017","unstructured":"Galderisi M, Cosyns B, Edvardsen T et al (2017) Standardization of adult transthoracic echocardiography reporting in agreement with recent chamber quantification, diastolic function, and heart valve disease recommendations: an expert consensus document of the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 18:1301\u20131310","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"3179_CR12","doi-asserted-by":"publisher","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","volume":"6","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6:e1000097","journal-title":"PLoS Med"},{"key":"3179_CR13","first-page":"7","volume":"7","author":"LL Ma","year":"2020","unstructured":"Ma LL, Wang YY, Yang ZH, Huang D, Weng H, Zeng XT (2020) Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better? Mil Med Res 7:7","journal-title":"Mil Med Res"},{"key":"3179_CR14","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1016\/j.amjcard.2013.05.031","volume":"112","author":"C Zito","year":"2013","unstructured":"Zito C, Carerj S, Todaro MC et al (2013) Myocardial deformation and rotational profiles in mitral valve prolapse. Am J Cardiol 112:984\u2013990","journal-title":"Am J Cardiol"},{"key":"3179_CR15","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1017\/S1047951113001042","volume":"24","author":"E Malev","year":"2014","unstructured":"Malev E, Reeva S, Vasina L et al (2014) Cardiomyopathy in young adults with classic mitral valve prolapse. Cardiol Young 24:694\u2013701","journal-title":"Cardiol Young"},{"key":"3179_CR16","doi-asserted-by":"publisher","first-page":"e005113","DOI":"10.1161\/CIRCIMAGING.115.005113","volume":"9","author":"S Fukuda","year":"2016","unstructured":"Fukuda S, Song JK, Mahara K et al (2016) Basal left ventricular dilatation and reduced contraction in patients with mitral valve prolapse can be secondary to annular dilatation: preoperative and postoperative speckle-tracking echocardiographic study on left ventricle and mitral valve Annulus Interaction. Circ Cardiovasc Imaging 9:e005113","journal-title":"Circ Cardiovasc Imaging"},{"key":"3179_CR17","first-page":"323","volume":"18","author":"O Huttin","year":"2017","unstructured":"Huttin O, Pierre S, Venner C et al (2017) Interactions between mitral valve and left ventricle analysed by 2D speckle tracking in patients with mitral valve prolapse: one more piece to the puzzle. Eur Heart J Cardiovasc Imaging 18:323\u2013331","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"3179_CR18","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1016\/j.jcmg.2016.11.022","volume":"10","author":"AP Lee","year":"2017","unstructured":"Lee AP, Jin CN, Fan Y, Wong RHL, Underwood MJ, Wan S (2017) Functional implication of mitral annular disjunction in mitral valve prolapse: a quantitative dynamic 3D echocardiographic study. JACC Cardiovasc Imaging 10:1424\u20131433","journal-title":"JACC Cardiovasc Imaging"},{"key":"3179_CR19","doi-asserted-by":"publisher","first-page":"1992","DOI":"10.1016\/j.amjcard.2019.03.009","volume":"123","author":"SF \u00c7elik","year":"2019","unstructured":"\u00c7elik SF (2019) Early impairment left ventricular mechanics in children with mitral valve prolapse. Am J Cardiol 123:1992\u20131998","journal-title":"Am J Cardiol"},{"key":"3179_CR20","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1136\/heartjnl-2018-314269","volume":"105","author":"S Ermakov","year":"2019","unstructured":"Ermakov S, Gulhar R, Lim L et al (2019) Left ventricular mechanical dispersion predicts arrhythmic risk in mitral valve prolapse. Heart 105:1063\u20131069","journal-title":"Heart"},{"key":"3179_CR21","doi-asserted-by":"publisher","first-page":"2155","DOI":"10.1007\/s10554-020-01931-4","volume":"36","author":"M Castillo-Sang","year":"2020","unstructured":"Castillo-Sang M, Palmer C, Truong VT et al (2020) Abnormal ventricular contractile pattern associated with late systolic mitral prolapse: a two-dimensional speckle tracking study. Int J Cardiovasc Imaging 36:2155\u20132164","journal-title":"Int J Cardiovasc Imaging"},{"key":"3179_CR22","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.ihj.2020.11.010","volume":"73","author":"GN Rajesh","year":"2021","unstructured":"Rajesh GN, Shyam Lakshman SG, Vellani H, Sajeev CG, Thomas B (2021) Strain patterns in primary mitral regurgitation due to rheumatic heart disease and mitral valve prolapse. Indian Heart J 73:85\u201390","journal-title":"Indian Heart J"},{"key":"3179_CR23","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1007\/s10554-020-02085-z","volume":"37","author":"A Sonaglioni","year":"2021","unstructured":"Sonaglioni A, Nicolosi GL, Lombardo M, Gensini GF, Ambrosio G (2021) Influence of chest conformation on myocardial strain parameters in healthy subjects with mitral valve prolapse. Int J Cardiovasc Imaging 37:1009\u20131022","journal-title":"Int J Cardiovasc Imaging"},{"key":"3179_CR24","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.ijcard.2021.04.052","volume":"334","author":"TKM Wang","year":"2021","unstructured":"Wang TKM, Kwon DH, Abou-Hassan O et al (2021) Strain evaluation for mitral annular disjunction by echocardiography and magnetic resonance imaging: a case-control study. Int J Cardiol 334:154\u2013156","journal-title":"Int J Cardiol"},{"key":"3179_CR25","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s10554-022-02705-w","volume":"39","author":"A Sonaglioni","year":"2023","unstructured":"Sonaglioni A, Nicolosi GL, Rigamonti E, Lombardo M (2023) The influence of chest wall conformation on myocardial strain parameters in a cohort of mitral valve prolapse patients with and without mitral annular disjunction. Int J Cardiovasc Imaging 39:61\u201376","journal-title":"Int J Cardiovasc Imaging"},{"key":"3179_CR26","doi-asserted-by":"publisher","first-page":"e014963","DOI":"10.1161\/CIRCIMAGING.122.014963","volume":"16","author":"Y Nagata","year":"2023","unstructured":"Nagata Y, Bertrand PB, Baliyan V et al (2023) Abnormal mechanics relate to myocardial fibrosis and ventricular arrhythmias in patients with mitral valve prolapse. Circ Cardiovasc Imaging 16:e014963","journal-title":"Circ Cardiovasc Imaging"},{"key":"3179_CR27","first-page":"181","volume":"10","author":"L Dani\u0142owicz-Szymanowicz","year":"2023","unstructured":"Dani\u0142owicz-Szymanowicz L, Zienciuk-Krajka A, Wabich E et al (2023) G. Left Ventricle Segmental Longitudinal strain and Regional Myocardial Work Index could help determine mitral valve prolapse patients with increased risk of ventricular arrhythmias. J Cardiovasc Dev Dis 10:181","journal-title":"J Cardiovasc Dev Dis"},{"key":"3179_CR28","doi-asserted-by":"crossref","unstructured":"Muthukumar L, Jahangir A, Ashraf M et al (2023) Myocardial work indices in bileaflet mitral valve prolapse patients. Eur Heart J Cardiovasc Imaging jead333","DOI":"10.1093\/ehjci\/jead333"},{"key":"3179_CR29","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1007\/s10554-018-1366-5","volume":"34","author":"A Sonaglioni","year":"2018","unstructured":"Sonaglioni A, Baravelli M, Vincenti A et al (2018) A new modified anthropometric haller index obtained without radiological exposure. Int J Cardiovasc Imaging 34:1505\u20131509","journal-title":"Int J Cardiovasc Imaging"},{"key":"3179_CR30","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1161\/CIRCULATIONAHA.115.016291","volume":"132","author":"C Basso","year":"2015","unstructured":"Basso C, Perazzolo Marra M, Rizzo S et al (2015) Arrhythmic mitral valve prolapse and Sudden Cardiac Death. Circulation 132:556\u2013566","journal-title":"Circulation"},{"key":"3179_CR31","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1016\/j.jacc.2018.06.048","volume":"72","author":"D Kitkungvan","year":"2018","unstructured":"Kitkungvan D, Nabi F, Kim RJ et al (2018) Myocardial fibrosis in patients with primary mitral regurgitation with and without Prolapse. J Am Coll Cardiol 72:823\u2013834","journal-title":"J Am Coll Cardiol"},{"key":"3179_CR32","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s12968-023-00944-x","volume":"25","author":"M Guglielmo","year":"2023","unstructured":"Guglielmo M, Arangalage D, Bonino MA et al (2023) Additional value of cardiac magnetic resonance feature tracking parameters for the evaluation of the arrhythmic risk in patients with mitral valve prolapse. J Cardiovasc Magn Reson 25:32","journal-title":"J Cardiovasc Magn Reson"},{"key":"3179_CR33","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1007\/s10554-023-03006-6","volume":"40","author":"A Cecere","year":"2024","unstructured":"Cecere A, Cipriani A, De Lazzari M et al (2024) Left ventricular fibrosis in arrhythmic mitral valve prolapse: quantification and comparison of semi-automated techniques assessed by cardiac magnetic resonance. Int J Cardiovasc Imaging 40:275\u2013285","journal-title":"Int J Cardiovasc Imaging"},{"key":"3179_CR34","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/s11739-021-02773-1","volume":"17","author":"A Sonaglioni","year":"2022","unstructured":"Sonaglioni A, Nicolosi GL, Rigamonti E, Lombardo M, Gensini GF, Ambrosio G (2022) Does chest shape influence exercise stress echocardiographic results in patients with suspected coronary artery disease? Intern Emerg Med 17:101\u2013112","journal-title":"Intern Emerg Med"},{"key":"3179_CR35","doi-asserted-by":"crossref","unstructured":"Sonaglioni A, Nicolosi GL, Rigamonti E, Lombardo M (2022) Impact of Chest Wall Conformation on the Outcome of Primary Mitral Regurgitation due to Mitral Valve Prolapse. J Cardiovasc Echogr 2022 32:29\u201337","DOI":"10.4103\/jcecho.jcecho_71_21"},{"key":"3179_CR36","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jcmg.2017.02.014","volume":"11","author":"O Mirea","year":"2018","unstructured":"Mirea O, Pagourelias ED, Duchenne J et al (2018) Intervendor differences in the Accuracy of detecting Regional Functional abnormalities: a Report from the EACVI-ASE strain standardization Task Force. JACC Cardiovasc Imaging 11:25\u201334","journal-title":"JACC Cardiovasc Imaging"},{"key":"3179_CR37","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1016\/j.jcmg.2016.06.012","volume":"10","author":"T Negishi","year":"2017","unstructured":"Negishi T, Negishi K, Thavendiranathan P et al (2017) Effect of experience and training on the Concordance and Precision of strain measurements. JACC Cardiovasc Imaging 10:518\u2013522","journal-title":"JACC Cardiovasc Imaging"},{"key":"3179_CR38","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1093\/ehjci\/jev058","volume":"16","author":"A R\u00f6sner","year":"2015","unstructured":"R\u00f6sner A, Barbosa D, Aars\u00e6ther E, Kj\u00f8n\u00e5s D, Schirmer H, D\u2019hooge J (2015) The influence of frame rate on two-dimensional speckle-tracking strain measurements: a study on silico-simulated models and images recorded in patients. Eur Heart J Cardiovasc Imaging 16:1137\u20131147","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"3179_CR39","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.ijcard.2023.03.058","volume":"381","author":"A Sonaglioni","year":"2023","unstructured":"Sonaglioni A, Nicolosi GL, Trevisan R et al (2023) The influence of pectus excavatum on cardiac kinetics and function in otherwise healthy individuals: a systematic review. Int J Cardiol 381:135\u2013144","journal-title":"Int J Cardiol"}],"container-title":["The International Journal of Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-024-03179-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10554-024-03179-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10554-024-03179-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T04:06:24Z","timestamp":1726286784000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10554-024-03179-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,8]]},"references-count":39,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["3179"],"URL":"https:\/\/doi.org\/10.1007\/s10554-024-03179-8","relation":{},"ISSN":["1875-8312"],"issn-type":[{"value":"1875-8312","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,8]]},"assertion":[{"value":"11 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed in the present study were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"We wish to confirm that there are no conflicts of interest associated with this publication. Andrea Sonaglioni declares that he has no conflict of interest. Valeria Fagiani declares that she has no conflict of interest. Gian Luigi Nicolosi declares that he has no conflict of interest. Michele Lombardo declares that he has no conflicts of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"N\/A.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}