{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T08:19:41Z","timestamp":1784621981820,"version":"3.55.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Cardiovasc Imaging"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study aims to compare the image quality between photon-counting detector computed tomography (PCD-CT) and energy-integrating CT (EID-CT) for coronary artery visualization post-heart transplant (HTx) patients, using a paired comparison within one patient. Consecutive HTx patients who underwent both 3rd generation dual source EID-CT and ultra-high-resolution PCD-CT scans as part of routine clinical care, with a maximum interval of two years between scans were included. Image quality was assessed subjectively using a 5-point Likert scale and quantitatively with the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Coronary segments were scored for presence, stenosis degree, presence of artifacts, and plaque composition. Thirty patients were included (mean age 50\u2009\u00b1\u200917 years; 21 (70%) men). The median interval between scans was 17[12\u201324] months. The median calcium score was 9[0\u201351] on the EID-CT scan and 25[0\u201392] on the PCD-CT. On the PCD-CT, 90% of coronary segments were rated very good or excellent compared to 71% on EID-CT (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Fewer segments were absent or non-evaluable due to size with PCD-CT compared to EID-CT (30% vs. 34%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). PCD-CT identified more mixed plaques (11% vs. 3%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). SNR and CNR were significantly higher on PCD-CT (22.1\u2009\u00b1\u20096.1 and 27.8\u2009\u00b1\u20096.8,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) than on EID-CT (14.3\u2009\u00b1\u20093.4 and 16.9\u2009\u00b1\u20093.6,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). The CT dose index volume was 6 [5-10] mGy on EID-CT and 19 [14-21] mGy on PCD-CT (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Ultra-high-resolution PCD-CT improves image quality compared to EID-CT in HTx patients. With superior SNR and CNR, and fewer non-evaluable segments, PCD-CT offers enhanced coronary artery visualization, though at the cost of an increased radiation dose.\n                  <\/jats:p>","DOI":"10.1007\/s10554-025-03433-7","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T12:44:55Z","timestamp":1748868295000},"page":"393-401","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of image quality between photon-counting detector CT and energy-integrating detector coronary CT angiography in heart transplant patients"],"prefix":"10.1007","volume":"42","author":[{"given":"Simran P.","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo P.J.","family":"Budde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Willem","family":"Groen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel L.","family":"Dijkshoorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier C.","family":"Manintveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,2]]},"reference":[{"issue":"8","key":"3433_CR1","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1016\/j.healun.2010.05.034","volume":"29","author":"MR Costanzo","year":"2010","unstructured":"Costanzo MR, Dipchand A, Starling R et al (2010) The international society of heart and lung transplantation guidelines for the care of heart transplant recipients. 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Approval was granted by the Ethics Committee of Erasmus Medical Centre, Rotterdam.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"S.P. Sharma received institutional support to Erasmus MC from Siemens Healthineers. J.W. Groen has no competing interest. M.L. Dijkshoorn received consulting fees from Siemens Healthineers. R. Budde received institutional support to Erasmus MC from Siemens Healthineers; lecture fee and travel reimbursement from Siemens Healthineers paid directly to Erasmus MC; lecture fee from Bayer; board member of the European Society of Cardiovascular Radiology and the Cardiovascular section of the Dutch Society of Radiology; editorial board member of Radiology: Cardiothoracic Imaging, European Heart Journal \u2013 Digital Health, and the European Journal of Hybrid Imaging; grant from HeartFlow to Erasmus MC. The Erasmus MC received institutional support by Siemens Healthineers and HeartFlow. O. Manintveld received lecture fee and travel reimbursement from Siemens Healthineers paid directly to Erasmus MC. A. Hirsch received a research grant from GE Healthcare and consultancy\/speaker fees from GE Healthcare, Bayer, and Bristol Myers Squibb. He is advisory board member of Medis Medical Imaging Systems and was MRI corelab supervisor of Cardialysis BV until 2022.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}