{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:52:57Z","timestamp":1762505577757},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc Drugs Ther"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1007\/s10557-010-6223-2","type":"journal-article","created":{"date-parts":[[2010,3,29]],"date-time":"2010-03-29T09:31:22Z","timestamp":1269855082000},"page":"77-83","source":"Crossref","is-referenced-by-count":14,"title":["The PACIFIC (Prevention of AtherothrombotiC Incidents Following Ischemic Coronary attack) Registry: Rationale and Design of a 2-Year Study in Patients Initially Hospitalised with Acute Coronary Syndrome in Japan"],"prefix":"10.1007","volume":"24","author":[{"name":"on behalf of the PACIFIC steering committee members","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsumi","family":"Miyauchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Morino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kengo","family":"Tsukahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Origasa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Daida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,3,30]]},"reference":[{"key":"6223_CR1","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1159\/000047782","volume":"13","author":"L Drouet","year":"2002","unstructured":"Drouet L. Atherothrombosis as a systemic disease. Cerebrovasc Dis. 2002;13:S1\u20136.","journal-title":"Cerebrovasc Dis"},{"key":"6223_CR2","first-page":"3B","volume":"15","author":"DL Bhatt","year":"2003","unstructured":"Bhatt DL. Diffuse coronary disease and atherothrombosis: a rationale for long-term therapy to prevent recurrent ischemic events. J Invasive Cardiol. 2003;15:3B\u20139. discussion B\u201310B.","journal-title":"J Invasive Cardiol"},{"key":"6223_CR3","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1161\/01.RES.0000264509.36234.51","volume":"100","author":"TA Meadows","year":"2007","unstructured":"Meadows TA, Bhatt DL. Clinical aspects of platelet inhibitors and thrombus formation. Circ Res. 2007;100:1261\u201375.","journal-title":"Circ Res"},{"key":"6223_CR4","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.ehj.2004.03.011","volume":"25","author":"JF Viles-Gonzalez","year":"2004","unstructured":"Viles-Gonzalez JF, Fuster V, Badimon JJ. Atherothrombosis: a widespread disease with unpredictable and life-threatening consequences. Eur Heart J. 2004;25:1197\u2013207.","journal-title":"Eur Heart J"},{"key":"6223_CR5","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1161\/01.STR.0000090348.52943.A2","volume":"34","author":"M Kubo","year":"2003","unstructured":"Kubo M, Kiyohara Y, Kato I, et al. Trends in the incidence, mortality, and survival rate of cardiovascular disease in a Japanese community: the Hisayama study. Stroke. 2003;34:2349\u201354.","journal-title":"Stroke"},{"key":"6223_CR6","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1046\/j.1467-789X.2002.00070.x","volume":"3","author":"N Yoshiike","year":"2002","unstructured":"Yoshiike N, Seino F, Tajima S, et al. Twenty-year changes in the prevalence of overweight in Japanese adults: the National Nutrition Survey 1976\u201395. Obes Rev. 2002;3:183\u201390.","journal-title":"Obes Rev"},{"key":"6223_CR7","first-page":"15","volume":"57","author":"H Adachi","year":"2005","unstructured":"Adachi H, Hino A, Imaizumi T. Prediction of cardiovascular morbidity and mortality based on changes of cholesterol levels in Japan. Cardioangiology. 2005;57:15\u201320.","journal-title":"Cardioangiology"},{"key":"6223_CR8","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1001\/jama.294.10.1255","volume":"294","author":"A Jemal","year":"2005","unstructured":"Jemal A, Ward E, Hao Y, Thun M. Trends in the leading causes of death in the United States, 1970\u20132002. JAMA. 2005;294:1255\u20139.","journal-title":"JAMA"},{"key":"6223_CR9","first-page":"e25","volume":"117","author":"W Rosamond","year":"2008","unstructured":"Rosamond W, Flegal K, Furie K, et al. Heart disease and stroke statistics\u20132008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2008;117:e25\u2013146.","journal-title":"Circulation"},{"key":"6223_CR10","doi-asserted-by":"crossref","first-page":"144","DOI":"10.2188\/jea.JE2007438","volume":"18","author":"S Ishikawa","year":"2008","unstructured":"Ishikawa S, Kayaba K, Gotoh T, et al. Incidence of Total Stroke, Stroke Subtypes, and Myocardial Infarction in the Japanese Population: The JMS Cohort Study. J Epidemiol. 2008;18:144\u201350.","journal-title":"J Epidemiol"},{"key":"6223_CR11","doi-asserted-by":"crossref","unstructured":"Current status of the background of patients with coronary artery disease in Japan. Circ J. 2006;70:1256\u201362.","DOI":"10.1253\/circj.70.1256"},{"key":"6223_CR12","first-page":"1123","volume":"66 Suppl IV","author":"T Yamaguchi","year":"2002","unstructured":"Yamaguchi T, Ishikawa K, Isshiki T, et al. Guidelines for management of acute coronary syndrome without persistent ST segment elevation. Circ J. 2002;66 Suppl IV:1123\u201363.","journal-title":"Circ J"},{"key":"6223_CR13","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1253\/circj.71.1835","volume":"71","author":"T Kohro","year":"2007","unstructured":"Kohro T, Hayashi D, Okada Y, et al. Effects of medication on cardiovascular events in the Japanese coronary artery disease (JCAD) study. Circ J. 2007;71:1835\u201340.","journal-title":"Circ J"},{"key":"6223_CR14","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1253\/circj.71.1335","volume":"71","author":"Y Yui","year":"2007","unstructured":"Yui Y, Hirayama A, Nonogi H, et al. Unstable angina and non-ST elevation acute coronary syndrome: epidemiology and current management in Japan (Japan Multicenter Investigation for Cardiovascular Disease-D (JMIC-D) Committee). Circ J. 2007;71:1335\u201347.","journal-title":"Circ J"},{"key":"6223_CR15","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1253\/circj.71.995","volume":"71","author":"T Yamazaki","year":"2007","unstructured":"Yamazaki T, Goto S, Shigematsu H, et al. Prevalence, awareness and treatment of cardiovascular risk factors in patients at high risk of atherothrombosis in Japan. Circ J. 2007;71:995\u20131003.","journal-title":"Circ J"},{"key":"6223_CR16","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1001\/jama.297.11.1197","volume":"297","author":"PG Steg","year":"2007","unstructured":"Steg PG, Bhatt DL, Wilson PW, et al. One-year cardiovascular event rates in outpatients with atherothrombosis. JAMA. 2007;297:1197\u2013206.","journal-title":"JAMA"},{"key":"6223_CR17","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1001\/jama.295.2.180","volume":"295","author":"DL Bhatt","year":"2006","unstructured":"Bhatt DL, Steg PG, Ohman EM, et al. International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA. 2006;295:180\u20139.","journal-title":"JAMA"},{"key":"6223_CR18","doi-asserted-by":"crossref","unstructured":"A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet. 1996;348:1329\u201339.","DOI":"10.1016\/S0140-6736(96)09457-3"},{"key":"6223_CR19","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1056\/NEJMoa010746","volume":"345","author":"S Yusuf","year":"2001","unstructured":"Yusuf S, Zhao F, Mehta SR, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345:494\u2013502.","journal-title":"N Engl J Med"},{"key":"6223_CR20","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1001\/jama.285.13.1711","volume":"285","author":"GG Schwartz","year":"2001","unstructured":"Schwartz GG, Olsson AG, Ezekowitz MD, et al. Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes: the MIRACL study: a randomized controlled trial. JAMA. 2001;285:1711\u20138.","journal-title":"JAMA"},{"key":"6223_CR21","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1067\/mhj.2001.112404","volume":"141","author":"GRACE Investigators","year":"2001","unstructured":"GRACE Investigators. Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: a multinational registry of patients hospitalized with acute coronary syndromes. Am Heart J. 2001;141:190\u20139.","journal-title":"Am Heart J"},{"key":"6223_CR22","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1053\/euhj.2002.3193","volume":"23","author":"D Hasdai","year":"2002","unstructured":"Hasdai D, Behar S, Wallentin L, et al. A prospective survey of the characteristics, treatments and outcomes of patients with acute coronary syndromes in Europe and the Mediterranean basin; the Euro Heart Survey of Acute Coronary Syndromes (Euro Heart Survey ACS). Eur Heart J. 2002;23:1190\u2013201.","journal-title":"Eur Heart J"}],"container-title":["Cardiovascular Drugs and Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10557-010-6223-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10557-010-6223-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10557-010-6223-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T13:28:06Z","timestamp":1559222886000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10557-010-6223-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["6223"],"URL":"https:\/\/doi.org\/10.1007\/s10557-010-6223-2","relation":{},"ISSN":["0920-3206","1573-7241"],"issn-type":[{"type":"print","value":"0920-3206"},{"type":"electronic","value":"1573-7241"}],"subject":[],"published":{"date-parts":[[2010,2]]}}}