{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:58:24Z","timestamp":1760299104724},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2015,3,14]],"date-time":"2015-03-14T00:00:00Z","timestamp":1426291200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Drugs Ther"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1007\/s10557-015-6579-4","type":"journal-article","created":{"date-parts":[[2015,3,13]],"date-time":"2015-03-13T05:53:03Z","timestamp":1426225983000},"page":"107-109","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Development and Regulatory Approval of Acute Heart Failure Drugs in Japan"],"prefix":"10.1007","volume":"29","author":[{"given":"Kaori","family":"Shinagawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,3,14]]},"reference":[{"key":"6579_CR1","doi-asserted-by":"crossref","unstructured":"Asakura M, Yamamoto H, Asai K, et al. Rationale and design of double-blind, randomized, placebo-controlled multicenter trial on efficacy of early initiation of eplerenone treatment in patients with acute heart failure (EARLIER). Cardiovasc Drugs Ther 2015;29:this issue.","DOI":"10.1007\/s10557-014-6565-2"},{"key":"6579_CR2","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1253\/circj.CJ-08-0323","volume":"72","author":"N Kawashiro","year":"2008","unstructured":"Kawashiro N, Kasanuki H, Ogawa H, Matsuda N, Hagiwara N, Heart Institute of Japan-Department of Cardiology (HIJC) Investigators. Clinical characteristics and outcome of hospitalized patients with congestive heart failure: results of the HIJC-HF registry. Circ J. 2008;72:2015\u201320.","journal-title":"Circ J"},{"key":"6579_CR3","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.ahj.2010.03.019","volume":"159","author":"N Sato","year":"2010","unstructured":"Sato N, Kajimoto K, Asai K, ATTEND Investigators, et al. Acute decompensated heart failure syndromes (ATTEND) registry: A prospective observational multicenter cohort study: Rationale, design, and preliminary data. Am Heart J. 2010;159:949\u201355.","journal-title":"Am Heart J"},{"key":"6579_CR4","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1253\/circj.CJ-09-0316","volume":"73","author":"S Hamaguchi","year":"2009","unstructured":"Hamaguchi S, Yokoshiki H, Kinugawa S, Japanese Cardiac Registry of Heart Failure in Cardiology Investigators, et al. Effects of atrial fibrillation on long-term outcomes in patients hospitalized for heart failure in Japan: a report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). Circ J. 2009;73:2084\u201390.","journal-title":"Circ J"},{"key":"6579_CR5","unstructured":"Guidelines for the diagnosis and treatment of cardiovascular diseases (1998\u20131999 Joint Working Groups Report). Guidelines for treatment of severe acute heart failure. Jpn Circ J 2000;64 (Suppl IV):1129\u201365 (in Japanese)."},{"key":"6579_CR6","unstructured":"Guidelines for the diagnosis and treatment of cardiovascular diseases (2004\u20132005 Joint Working Groups Report). Guidelines for treatment of acute heart failure (JCS 2006). http:\/\/www.j-circ.or.jp\/guideline\/pdf\/JCS2006_maruyama_h.pdf (in Japanese)."},{"key":"6579_CR7","unstructured":"Guidelines for the diagnosis and treatment of cardiovascular diseases (2010 Joint Working Groups Report). Guidelines for Treatment of Acute Heart Failure (JCS 2011). http:\/\/www.j-circ.or.jp\/guideline\/pdf\/JCS2011_izumi_h.pdf (in Japanese)."},{"key":"6579_CR8","first-page":"1239","volume":"12","author":"V-P Harjola","year":"2010","unstructured":"Harjola V-P, Follath F, Nieminen MS, et al. Characteristics, outcomes, and predictors of mortality at 3 months and 1 year in patients hospitalized for acute heart failure. Eur J Heart Fail. 2010;12:1239\u201348.","journal-title":"Eur J Heart Fail"},{"key":"6579_CR9","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/clpt.2010.31","volume":"87","author":"FL Arnold","year":"2010","unstructured":"Arnold FL, Kusama M, Ono S. Exploring differences in drug doses between Japan and Western countries. Clin Pharmacol Ther. 2010;87:714\u201320.","journal-title":"Clin Pharmacol Ther"},{"key":"6579_CR10","unstructured":"Guidelines for clinical evaluation of heart failure drugs. http:\/\/www.pmda.go.jp\/kijunsakusei\/file\/guideline\/new_drug\/kou-shinfuzenyaku-rinjyu-hyouka-guideline.pdf (in Japanese)."}],"container-title":["Cardiovascular Drugs and Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10557-015-6579-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10557-015-6579-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10557-015-6579-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T13:28:21Z","timestamp":1559222901000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10557-015-6579-4"}},"subtitle":["Editorial to: \u201cRationale and Design of Double-Blind, Randomized, Placebo-Controlled Multicenter Trial on Efficacy of Early Initiation of Eplerenone Treatment in Patients with Acute Heart Failure (EARLIER)\u201d by M. Asakura et al."],"short-title":[],"issued":{"date-parts":[[2015,3,14]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["6579"],"URL":"https:\/\/doi.org\/10.1007\/s10557-015-6579-4","relation":{},"ISSN":["0920-3206","1573-7241"],"issn-type":[{"value":"0920-3206","type":"print"},{"value":"1573-7241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,14]]}}}