{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T06:09:12Z","timestamp":1778652552522,"version":"3.51.4"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Drugs Ther"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s10557-025-07778-y","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T08:26:21Z","timestamp":1757665581000},"page":"811-812","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Optimizing Lipid-Lowering Strategies Beyond Current Evidence"],"prefix":"10.1007","volume":"40","author":[{"given":"Mucahit","family":"Yetim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abd\u00fclmelik","family":"Birg\u00fcn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8791-4475","authenticated-orcid":false,"given":"Macit","family":"Kal\u00e7\u0131k","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,12]]},"reference":[{"key":"7778_CR1","doi-asserted-by":"publisher","DOI":"10.1007\/s10557-025-07729-7","author":"SY Sohn","year":"2025","unstructured":"Sohn SY, Kim YJ, Doh JH, Cho SW. Moderate-\u0131ntensity atorvastatin and ezetimibe combination therapy versus high-\u0131ntensity atorvastatin in patients with angina pectoris who underwent percutaneous coronary \u0131ntervention. Cardiovasc Drugs Ther. 2025. https:\/\/doi.org\/10.1007\/s10557-025-07729-7.","journal-title":"Cardiovasc Drugs Ther"},{"key":"7778_CR2","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1016\/S0140-6736(22)00916-3","volume":"400","author":"BK Kim","year":"2022","unstructured":"Kim BK, Hong SJ, Lee YJ, et al. Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy (RACING trial). Lancet. 2022;400:380\u201390.","journal-title":"Lancet"},{"issue":"5","key":"7778_CR3","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.jacc.2023.05.042","volume":"82","author":"SJ Lee","year":"2023","unstructured":"Lee SJ, Joo JH, Park S, et al. Combination lipid-lowering therapy in patients undergoing PCI: generalizability of RACING. J Am Coll Cardiol. 2023;82(5):401\u201310.","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"7778_CR4","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1002\/cpt.1859","volume":"108","author":"YC Lin","year":"2020","unstructured":"Lin YC, Lai TS, Wu HY, et al. Effects and safety of statin and ezetimibe combination therapy in CKD: a systematic review and meta-analysis. Clin Pharmacol Ther. 2020;108(4):833\u201343.","journal-title":"Clin Pharmacol Ther"},{"issue":"8","key":"7778_CR5","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1093\/eurheartj\/ehab718","volume":"43","author":"KK Ray","year":"2022","unstructured":"Ray KK, Reeskamp LF, Laufs U, et al. Combination lipid-lowering therapy as first-line strategy in very high-risk patients. Eur Heart J. 2022;43(8):830\u20133.","journal-title":"Eur Heart J"},{"issue":"1","key":"7778_CR6","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1007\/s10557-023-07511-7","volume":"39","author":"S Liu","year":"2025","unstructured":"Liu S, Hou J, Wan J, et al. Effect of \u0131ntensive lipid-lowering therapy on coronary plaque stabilization derived from optical coherence tomography: a meta-analysis and meta-regression. Cardiovasc Drugs Ther. 2025;39(1):119\u201332.","journal-title":"Cardiovasc Drugs Ther"},{"key":"7778_CR7","doi-asserted-by":"publisher","unstructured":"Chen C, Wei FF, Dong Y, Liu C. Early management of blood lipid levels with non-statin lipid-lowering drugs in acute coronary syndrome: a mini review. Cardiovasc Drugs Ther. Published online June 29, 2024.\u00a0https:\/\/doi.org\/10.1007\/s10557-024-07587-9.","DOI":"10.1007\/s10557-024-07587-9"},{"key":"7778_CR8","doi-asserted-by":"publisher","unstructured":"Ahebkar A, Reiner \u017d, Almahmeed W, Jamialahmadi T, Simental-Mend\u00eda LE. Effect of statin treatment on lipoprotein-associated phospholipase A2 mass and activity: a systematic review and meta-analysis of randomized placebo-controlled trials. Cardiovasc Drugs Ther. Published online October 28, 2024.\u00a0https:\/\/doi.org\/10.1007\/s10557-024-07634-5.","DOI":"10.1007\/s10557-024-07634-5"}],"container-title":["Cardiovascular Drugs and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10557-025-07778-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10557-025-07778-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10557-025-07778-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T05:21:25Z","timestamp":1778649685000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10557-025-07778-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,12]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["7778"],"URL":"https:\/\/doi.org\/10.1007\/s10557-025-07778-y","relation":{},"ISSN":["0920-3206","1573-7241"],"issn-type":[{"value":"0920-3206","type":"print"},{"value":"1573-7241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,12]]},"assertion":[{"value":"2 September 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 September 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}]}}