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In our outpatient clinic, we found two patients with recurrent nerve entrapment syndrome with significant symptoms such as complete sensory loss and chronic pain who were willing to undergo re-exploration of their entrapped nerves and cover them with a human acellular dermal matrix (ADM) as a protective shield against recurrence. Both patients had complete recovery of the nerve entrapment syndrome with satisfactory clinical results. The use of a human ADM appears to be a promising tool for recurrent nerve entrapment surgery without adding morbidity to the procedure.<\/jats:p>","DOI":"10.1007\/s10561-025-10159-2","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:36:11Z","timestamp":1738715771000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Using an acellular dermal matrix as a neuroprotective wrap-around for treating recurrent nerve entrapment syndromes: a proof of concept"],"prefix":"10.1007","volume":"26","author":[{"given":"Till","family":"Wagner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dietmar J. 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