{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:15:43Z","timestamp":1791558943845,"version":"4.3.4"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Tissue Bank"],"DOI":"10.1007\/s10561-026-10210-w","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T10:11:30Z","timestamp":1770718290000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of donor\u2013recipient gender mismatch on outcomes in Descemet membrane endothelial keratoplasty (DMEK)"],"prefix":"10.1007","volume":"27","author":[{"given":"Zoe","family":"Eckly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre M.","family":"Trouvain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"della Volpe-Waizel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara E.","family":"Englisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Szurman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berthold","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Fries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annekatrin","family":"Rickmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"10210_CR1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/1520912","volume":"2022","author":"A Achiron","year":"2022","unstructured":"Achiron A, Yahalomi T, Hecht I, Stanescu N, Achiron Noy R, Burgansky-Eliash Z, Avizemer H, Tuuminen R, Spierer O (2022) Donor and recipient sex matching and corneal graft failure in high-risk and non-high-risk patients. J Ophthalmol 2022:1520912. https:\/\/doi.org\/10.1155\/2022\/1520912","journal-title":"J Ophthalmol"},{"key":"10210_CR2","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1097\/01.tp.0000235908.54766.44","volume":"82","author":"D B\u00f6hringer","year":"2006","unstructured":"B\u00f6hringer D, Spierings E, Enczmann J, B\u00f6hringer S, Sundmacher R, Goulmy E, Reinhard T (2006) Matching of the minor histocompatibility antigen HLA-A1\/H-Y may improve prognosis in corneal transplantation. Transplantation 82:1037\u20131041. https:\/\/doi.org\/10.1097\/01.tp.0000235908.54766.44","journal-title":"Transplantation"},{"key":"10210_CR3","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1016\/s0140-6736(95)91797-7","volume":"346","author":"D Candinas","year":"1995","unstructured":"Candinas D, Gunson BK, Nightingale P, Hubscher S, McMaster P, Neuberger JM (1995) Sex mismatch as a risk factor for chronic rejection of liver allografts. Lancet 346:1117\u20131121. https:\/\/doi.org\/10.1016\/s0140-6736(95)91797-7","journal-title":"Lancet"},{"key":"10210_CR151","unstructured":"Cherry PM, Pashby RC, Tadros ML, Wolf A, Chipman ML, Basu PK, Dixon WS, Hunter WS, (1979) Thompson GA. An analysis of corneal transplantation: II--postoperative astigmatism. Ann Ophthalmol 11(4):669\u2013672."},{"key":"10210_CR4","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1016\/j.survophthal.2016.12.010","volume":"62","author":"A Di Zazzo","year":"2017","unstructured":"Di Zazzo A, Kheirkhah A, Abud TB, Goyal S, Dana R (2017) Management of high-risk corneal transplantation. Surv Ophthalmol 62:816\u2013827. https:\/\/doi.org\/10.1016\/j.survophthal.2016.12.010","journal-title":"Surv Ophthalmol"},{"key":"10210_CR5","doi-asserted-by":"publisher","DOI":"10.1136\/bmjophth-2021-000965","author":"L Downward","year":"2022","unstructured":"Downward L, Ahmed M, Hopkinson C, Romano V, Curnow E, Kaye SB (2022) Endothelial failure and rejection in recipients of corneas from the same donor. BMJ Open Ophthalmol. https:\/\/doi.org\/10.1136\/bmjophth-2021-000965","journal-title":"BMJ Open Ophthalmol"},{"key":"10210_CR6","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s10561-020-09864-x","volume":"22","author":"A Fasolo","year":"2021","unstructured":"Fasolo A, Gallon P, Frigo AC, Birattari F, Monterosso C, Rapizzi E, Brighenti T, Pedrotti E, Marro C, Viola P, Ponzin D, Franch A (2021) Gender medicine in corneal transplantation: influence of sex mismatch on rejection episodes and graft survival in a prospective cohort of patients. Cell Tissue Bank 22:47\u201356. https:\/\/doi.org\/10.1007\/s10561-020-09864-x","journal-title":"Cell Tissue Bank"},{"key":"10210_CR7","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1136\/bjo-2022-323162","volume":"108","author":"E Flockerzi","year":"2024","unstructured":"Flockerzi E, Turner C, Seitz B, Collaborators GSG (2024) Descemet\u2019s membrane endothelial keratoplasty is the predominant keratoplasty procedure in Germany since 2016: a report of the DOG-section cornea and its keratoplasty registry. Br J Ophthalmol 108:646\u2013653. https:\/\/doi.org\/10.1136\/bjo-2022-323162","journal-title":"Br J Ophthalmol"},{"key":"10210_CR8","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1007\/s00417-015-3248-z","volume":"254","author":"S Heinzelmann","year":"2016","unstructured":"Heinzelmann S, B\u00f6hringer D, Eberwein P, Reinhard T, Maier P (2016) Outcomes of Descemet membrane endothelial keratoplasty, Descemet stripping automated endothelial keratoplasty and penetrating keratoplasty from a single centre study. Graefes Arch Clin Exp Ophthalmol 254:515\u2013522. https:\/\/doi.org\/10.1007\/s00417-015-3248-z","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10210_CR9","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1111\/ajt.13926","volume":"17","author":"CL Hopkinson","year":"2017","unstructured":"Hopkinson CL, Romano V, Kaye RA, Steger B, Stewart RMK, Tsagkataki M, Jones MNA, Larkin DFP, Kaye SB (2017) The influence of donor and recipient gender incompatibility on corneal transplant rejection and failure. Am J Transplant 17:210\u2013217. https:\/\/doi.org\/10.1111\/ajt.13926","journal-title":"Am J Transplant"},{"key":"10210_CR152","doi-asserted-by":"publisher","unstructured":"Inoue K, Amano S, Oshika T, Tsuru T. (2000) Histocompatibility Y antigen compatibility and allograft rejection in corneal transplantation. Eye (Lond). 14(2):201-205. https:\/\/doi.org\/10.1038\/eye.2000.54","DOI":"10.1038\/eye.2000.54"},{"key":"10210_CR10","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1016\/0003-4975(93)90281-l","volume":"55","author":"M Kawauchi","year":"1993","unstructured":"Kawauchi M, Gundry SR, de Begona JA, Fullerton DA, Razzouk AJ, Boucek MM, Nehlsen-Cannarella S, Bailey LL (1993) Male donor into female recipient increases the risk of pediatric heart allograft rejection. Ann Thorac Surg 55:716\u2013718. https:\/\/doi.org\/10.1016\/0003-4975(93)90281-l","journal-title":"Ann Thorac Surg"},{"key":"10210_CR11","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1097\/ico.0000000000001394","volume":"37","author":"MJ Kim","year":"2018","unstructured":"Kim MJ, Kim JH, Jeon HS, Wee WR, Hyon JY (2018) Effect of histocompatibility Y antigen matching on graft survival in primary penetrating keratoplasty. Cornea 37:33\u201338. https:\/\/doi.org\/10.1097\/ico.0000000000001394","journal-title":"Cornea"},{"key":"10210_CR12","doi-asserted-by":"publisher","DOI":"10.37039\/1982.8551.20220037","author":"LMM Maia","year":"2022","unstructured":"Maia LMM, Lima LEF, de Almeida MF, de Paula RVP, Sousa ENL, Ferreira JdLM, Da Silva LP (2022) Epidemiology of corneal transplantation before achieving the Zero Queue. Rev Bras Oftalmol. https:\/\/doi.org\/10.37039\/1982.8551.20220037","journal-title":"Rev Bras Oftalmol"},{"key":"10210_CR13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0263686","volume":"17","author":"V Malleron","year":"2022","unstructured":"Malleron V, Bloch F, Zevering Y, Vermion J-C, Semler-Collery A, Goetz C, Perone J-M (2022) Evolution of corneal transplantation techniques and their indications in a French corneal transplant unit in 2000\u20132020. PLoS ONE 17:e0263686. https:\/\/doi.org\/10.1371\/journal.pone.0263686","journal-title":"PLoS ONE"},{"key":"10210_CR14","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1034\/j.1399-0039.2003.00062.x","volume":"61","author":"D Middleton","year":"2003","unstructured":"Middleton D, Menchaca L, Rood H, Komerofsky R (2003) New allele frequency database: http:\/\/www.allelefrequencies.net. Tissue Antigens 61:403\u2013407. https:\/\/doi.org\/10.1034\/j.1399-0039.2003.00062.x","journal-title":"Tissue Antigens"},{"key":"10210_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000099234","volume":"92","author":"JY Niederkorn","year":"2007","unstructured":"Niederkorn JY, Kaplan HJ (2007) Rationale for immune response and the eye. Chem Immunol Allergy 92:1\u20133. https:\/\/doi.org\/10.1159\/000099234","journal-title":"Chem Immunol Allergy"},{"key":"10210_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2020.100863","volume":"80","author":"S Ong Tone","year":"2021","unstructured":"Ong Tone S, Kocaba V, B\u00f6hm M, Wylegala A, White TL, Jurkunas UV (2021) Fuchs endothelial corneal dystrophy: the vicious cycle of Fuchs pathogenesis. Prog Retin Eye Res 80:100863. https:\/\/doi.org\/10.1016\/j.preteyeres.2020.100863","journal-title":"Prog Retin Eye Res"},{"key":"10210_CR17","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1097\/ico.0000000000001189","volume":"36","author":"IO Potapenko","year":"2017","unstructured":"Potapenko IO, Samolov B, Armitage MC, Bystr\u00f6m B, Hjortdal J (2017) Donor endothelial cell count does not correlate with Descemet stripping automated endothelial keratoplasty transplant survival after 2 years of follow-up. Cornea 36:649\u2013654. https:\/\/doi.org\/10.1097\/ico.0000000000001189","journal-title":"Cornea"},{"key":"10210_CR18","doi-asserted-by":"publisher","first-page":"1508","DOI":"10.1016\/j.ophtha.2018.03.050","volume":"125","author":"DA Price","year":"2018","unstructured":"Price DA, Kelley M, Price FW, Price MO (2018) Five-year graft survival of Descemet membrane endothelial keratoplasty (EK) versus Descemet stripping EK and the effect of donor sex matching. Ophthalmology 125:1508\u20131514. https:\/\/doi.org\/10.1016\/j.ophtha.2018.03.050","journal-title":"Ophthalmology"},{"key":"10210_CR19","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1146\/annurev-vision-102016-061400","volume":"3","author":"MO Price","year":"2017","unstructured":"Price MO, Gupta P, Lass J, Price FW (2017) EK (DLEK, DSEK, DMEK): new frontier in cornea surgery. Annu Rev vis Sci 3:69\u201390. https:\/\/doi.org\/10.1146\/annurev-vision-102016-061400","journal-title":"Annu Rev vis Sci"},{"key":"10210_CR20","doi-asserted-by":"publisher","first-page":"2295","DOI":"10.1007\/s10792-018-01067-4","volume":"39","author":"A Rickmann","year":"2019","unstructured":"Rickmann A, Wahl S, Katsen-Globa A, Szurman P (2019) Safety analysis and results of a borosilicate glass cartridge for no-touch graft loading and injection in Descemet membrane endothelial keratoplasty. Int Ophthalmol 39:2295\u20132301. https:\/\/doi.org\/10.1007\/s10792-018-01067-4","journal-title":"Int Ophthalmol"},{"key":"10210_CR150","doi-asserted-by":"publisher","unstructured":"Anshu A, Price MO, Price FW Jr. (2012) Risk of corneal transplant rejection significantly reduced with Descemet's membrane endothelial keratoplasty. Ophthalmology.  119(3):536\u2013540. https:\/\/doi.org\/10.1016\/j.ophtha.2011.09.019.","DOI":"10.1016\/j.ophtha.2011.09.019"},{"key":"10210_CR21","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1016\/j.healun.2003.09.014","volume":"23","author":"DH Roberts","year":"2004","unstructured":"Roberts DH, Wain JC, Chang Y, Ginns LC (2004) Donor-recipient gender mismatch in lung transplantation: impact on obliterative bronchiolitis and survival. J Heart Lung Transplant 23:1252\u20131259. https:\/\/doi.org\/10.1016\/j.healun.2003.09.014","journal-title":"J Heart Lung Transplant"},{"key":"10210_CR22","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.ajo.2021.09.029","volume":"235","author":"V Romano","year":"2022","unstructured":"Romano V, Parekh M, Virgili G, Coco G, Leon P, Islein K, Ponzin D, Ferrari S, Fasolo A, Yu AC, Lucenteforte E, Busin M, Kaye SB (2022) Gender matching did not affect 2-year rejection or failure rates following DSAEK for Fuchs endothelial corneal dystrophy. Am J Ophthalmol 235:204\u2013210. https:\/\/doi.org\/10.1016\/j.ajo.2021.09.029","journal-title":"Am J Ophthalmol"},{"key":"10210_CR23","first-page":"209","volume":"76","author":"D Scholz","year":"1983","unstructured":"Scholz D, Mebel M (1983) Zur Bedeutung geschlechtsdeterminierter Antigene f\u00fcr die Nierentransplantatprognose-Eine Analyse von 500 Transplantationen eines Zentrums (The significance of sex determined antigens for kidney transplantation prognosis\u2013an analysis of 500 transplantations at a center). Z Urol Nephrol 76:209\u2013217","journal-title":"Z Urol Nephrol"},{"key":"10210_CR24","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.ajo.2018.10.005","volume":"196","author":"RD Stulting","year":"2018","unstructured":"Stulting RD, Lass JH, Terry MA, Benetz BA, Cohen NJ, Ayala AR, Maguire MG, Croasdale C, Daoud YJ, Dunn SP, Goins KM, Gupta PC, Macsai MS, Mian SI, Pramanik S, Rose-Nussbaumer J, Song JC, Stark WJ, Sugar A, Verdier DD, Szczotka-Flynn LB (2018) Factors associated with graft rejection in the Cornea Preservation Time Study. Am J Ophthalmol 196:197\u2013207. https:\/\/doi.org\/10.1016\/j.ajo.2018.10.005","journal-title":"Am J Ophthalmol"},{"key":"10210_CR25","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1007\/s00417-016-3377-z","volume":"254","author":"P Szurman","year":"2016","unstructured":"Szurman P, Januschowski K, Rickmann A, Damm L-J, Boden KT, Opitz N (2016) Novel liquid bubble dissection technique for DMEK lenticule preparation. Graefes Arch Clin Exp Ophthalmol 254:1819\u20131823. https:\/\/doi.org\/10.1007\/s00417-016-3377-z","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10210_CR26","doi-asserted-by":"publisher","first-page":"1749","DOI":"10.1016\/s0140-6736(12)60437-1","volume":"379","author":"DTH Tan","year":"2012","unstructured":"Tan DTH, Dart JKG, Holland EJ, Kinoshita S (2012) Corneal transplantation. Lancet 379:1749\u20131761. https:\/\/doi.org\/10.1016\/s0140-6736(12)60437-1","journal-title":"Lancet"},{"key":"10210_CR27","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.preteyeres.2015.01.001","volume":"46","author":"TH van Essen","year":"2015","unstructured":"van Essen TH, Roelen DL, Williams KA, Jager MJ (2015) Matching for Human Leukocyte Antigens (HLA) in corneal transplantation - to do or not to do. Prog Retin Eye Res 46:84\u2013110. https:\/\/doi.org\/10.1016\/j.preteyeres.2015.01.001","journal-title":"Prog Retin Eye Res"},{"key":"10210_CR28","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1111\/j.1755-3768.1982.tb08373.x","volume":"60","author":"HJ V\u00f6lker-Dieben","year":"1982","unstructured":"V\u00f6lker-Dieben HJ, Kok-van Alphen CC, Lansbergen Q, Persijn GG (1982) Different influences on corneal graft survival in 539 transplants. Acta Ophthalmol (Copenh) 60(2):190\u2013202. https:\/\/doi.org\/10.1111\/j.1755-3768.1982.tb08373.x","journal-title":"Acta Ophthalmol (Copenh)"},{"key":"10210_CR29","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1161\/CIRCHEARTFAILURE.108.844183","volume":"2","author":"ES Weiss","year":"2009","unstructured":"Weiss ES, Allen JG, Patel ND, Russell SD, Baumgartner WA, Shah AS, Conte JV (2009) The impact of donor-recipient sex matching on survival after orthotopic heart transplantation: analysis of 18 000 transplants in the modern era. Circ Heart Fail 2:401\u2013408. https:\/\/doi.org\/10.1161\/CIRCHEARTFAILURE.108.844183","journal-title":"Circ Heart Fail"}],"container-title":["Cell and Tissue Banking"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10561-026-10210-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10561-026-10210-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10561-026-10210-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T03:17:45Z","timestamp":1773890265000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10561-026-10210-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,10]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,3]]}},"alternative-id":["10210"],"URL":"https:\/\/doi.org\/10.1007\/s10561-026-10210-w","relation":{},"ISSN":["1573-6814"],"issn-type":[{"value":"1573-6814","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,10]]},"assertion":[{"value":"9 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Prof. Peter Szurman has a patent for a device used for preparing and introducing a transplant or implant into a living body, in particular for ophthalmological interventions: EP2533724 B1; WO2012065602 A3. All other authors certify that they have no affiliations with or involvement in any organization or entity with financial interests (such as honoraria, educational grants, participation in speakers\u2019 bureaus, membership, employment, consultancies, stock ownership or other equity interest, and expert testimony or patent-licensing arrangements) or non-financial interests (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"10"}}