{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:01:47Z","timestamp":1780441307705,"version":"3.54.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Tissue Bank"],"DOI":"10.1007\/s10561-026-10218-2","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T06:54:12Z","timestamp":1774335252000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bioglass nanofibers in a 3D scaffold orchestrate robust bone regeneration via enhanced osteogenesis and mineralization"],"prefix":"10.1007","volume":"27","author":[{"given":"Nasrin","family":"Kheradmand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morteza","family":"Alizadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tayebe","family":"Artimani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lobat","family":"Tayebi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Azizi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadi","family":"Samadian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,24]]},"reference":[{"issue":"5","key":"10218_CR1","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1039\/D2TB02505A","volume":"11","author":"OD Abodunrin","year":"2023","unstructured":"Abodunrin OD, El Mabrouk K, Bricha M (2023) A review on borate bioactive glasses (BBG): effect of doping elements, degradation, and applications. J Mater Chem B 11(5):955\u2013973","journal-title":"J Mater Chem B"},{"issue":"23","key":"10218_CR2","doi-asserted-by":"publisher","first-page":"18340","DOI":"10.1021\/la102845k","volume":"26","author":"BA Allo","year":"2010","unstructured":"Allo BA, Rizkalla AS, Mequanint K (2010) Synthesis and electrospinning of \u03b5-polycaprolactone-bioactive glass hybrid biomaterials via a sol\u2212 gel process. Langmuir 26(23):18340\u201318348","journal-title":"Langmuir"},{"key":"10218_CR3","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.ijbiomac.2021.01.002","volume":"174","author":"E Azizipour","year":"2021","unstructured":"Azizipour E et al (2021) A novel hydrogel scaffold contained bioactive glass nanowhisker (BGnW) for osteogenic differentiation of human mesenchymal stem cells (hMSCs) in vitro. Int J Biol Macromol 174:562\u2013572","journal-title":"Int J Biol Macromol"},{"issue":"1","key":"10218_CR4","doi-asserted-by":"publisher","first-page":"4575","DOI":"10.1038\/s41467-024-48579-5","volume":"15","author":"MG Bixel","year":"2024","unstructured":"Bixel MG et al (2024) Angiogenesis is uncoupled from osteogenesis during calvarial bone regeneration. Nat Commun 15(1):4575","journal-title":"Nat Commun"},{"issue":"4","key":"10218_CR5","first-page":"963","volume":"5","author":"Y Chen","year":"2020","unstructured":"Chen Y et al (2020) Advanced fabrication for electrospun three-dimensional nanofiber aerogels and scaffolds. Bioact Mater 5(4):963\u2013979","journal-title":"Bioact Mater"},{"issue":"5","key":"10218_CR6","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1007\/s42765-022-00170-7","volume":"4","author":"Y Chen","year":"2022","unstructured":"Chen Y et al (2022) Recent advancements on three-dimensional electrospun nanofiber scaffolds for tissue engineering. Adv Fiber Mater 4(5):959\u2013986","journal-title":"Adv Fiber Mater"},{"issue":"24","key":"10218_CR7","doi-asserted-by":"publisher","first-page":"30793","DOI":"10.1021\/acsami.4c04199","volume":"16","author":"C Chen","year":"2024","unstructured":"Chen C et al (2024) Lithium promotes osteogenesis via Rab11a-Facilitated Exosomal Wnt10a secretion and \u03b2-Catenin signaling activation. ACS Appl Mater Interfaces 16(24):30793\u201330809","journal-title":"ACS Appl Mater Interfaces"},{"issue":"3","key":"10218_CR8","first-page":"408","volume":"10","author":"Y Choi","year":"2024","unstructured":"Choi Y et al (2024) Enhancing cell proliferation in three-dimensional hydrogel scaffolds using digital light processing bioprinting technology. Int J Bioprint 10(3):408\u2013425","journal-title":"Int J Bioprint"},{"issue":"21","key":"10218_CR9","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202010609","volume":"31","author":"MN Collins","year":"2021","unstructured":"Collins MN et al (2021) Scaffold fabrication technologies and structure\/function properties in bone tissue engineering. Adv Funct Mater 31(21):2010609","journal-title":"Adv Funct Mater"},{"issue":"6","key":"10218_CR10","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14061838","volume":"14","author":"R De Pace","year":"2025","unstructured":"De Pace R et al (2025) Bone regeneration: a review of current treatment strategies. J Clin Med 14(6):1838","journal-title":"J Clin Med"},{"issue":"9","key":"10218_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2023.108192","volume":"34","author":"L Dong","year":"2023","unstructured":"Dong L et al (2023) Copper carbonate nanoparticles as an effective biomineralized carrier to load macromolecular drugs for multimodal therapy. Chin Chem Lett 34(9):108192","journal-title":"Chin Chem Lett"},{"key":"10218_CR12","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.compstruct.2015.11.033","volume":"138","author":"S\u00d6 G\u00f6nen","year":"2016","unstructured":"G\u00f6nen S\u00d6, Taygun ME, K\u00fc\u00e7\u00fckbayrak S (2016) Fabrication of bioactive glass containing nanocomposite fiber mats for bone tissue engineering applications. Compos Struct 138:96\u2013106","journal-title":"Compos Struct"},{"key":"10218_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.130708","volume":"264","author":"X Guo","year":"2024","unstructured":"Guo X et al (2024) Recent advancements in hydrogels as novel tissue engineering scaffolds for dental pulp regeneration. Int J Biol Macromol 264:130708","journal-title":"Int J Biol Macromol"},{"key":"10218_CR14","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1016\/j.jconrel.2024.07.067","volume":"373","author":"X Hao","year":"2024","unstructured":"Hao X et al (2024) Nanomaterials for bone metastasis. J Control Release 373:640\u2013651","journal-title":"J Control Release"},{"issue":"8","key":"10218_CR15","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1007\/s10439-022-02970-9","volume":"50","author":"J Huang","year":"2022","unstructured":"Huang J et al (2022) Effect of angiogenesis in bone tissue engineering. Ann Biomed Eng 50(8):898\u2013913","journal-title":"Ann Biomed Eng"},{"issue":"12","key":"10218_CR16","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1002\/adfm.200500750","volume":"16","author":"HW Kim","year":"2006","unstructured":"Kim HW, Kim HE, Knowles JC (2006) Production and potential of bioactive glass nanofibers as a next\u2010generation biomaterial. Adv Funct Mater 16(12):1529\u20131535","journal-title":"Adv Funct Mater"},{"issue":"8","key":"10218_CR17","doi-asserted-by":"publisher","first-page":"914","DOI":"10.3390\/polym10080914","volume":"10","author":"S Kwon","year":"2018","unstructured":"Kwon S et al (2018) Bioglass-incorporated methacrylated gelatin cryogel for regeneration of bone defects. Polymers 10(8):914","journal-title":"Polymers"},{"key":"10218_CR18","doi-asserted-by":"crossref","unstructured":"Li, Y., X. Han, and Z. Ma, Research on the mechanical properties of PEEK material artificial bone implants fabricated by high-temperature air-assisted 3D printing. Journal of the Mechanical Behavior of Biomedical Materials, 2025: p. 107207","DOI":"10.1016\/j.jmbbm.2025.107207"},{"key":"10218_CR19","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/j.biomaterials.2018.11.007","volume":"192","author":"L Liu","year":"2019","unstructured":"Liu L et al (2019) Lithium-containing biomaterials stimulate bone marrow stromal cell-derived exosomal miR-130a secretion to promote angiogenesis. Biomaterials 192:523\u2013536","journal-title":"Biomaterials"},{"issue":"1","key":"10218_CR20","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-025-03448-1","volume":"23","author":"J Luo","year":"2025","unstructured":"Luo J et al (2025) Layered double hydroxides for regenerative nanomedicine and tissue engineering: recent advances and future perspectives. J Nanobiotechnology 23(1):370","journal-title":"J Nanobiotechnology"},{"issue":"7","key":"10218_CR21","doi-asserted-by":"publisher","first-page":"2016","DOI":"10.1097\/SCS.0000000000009593","volume":"34","author":"VV Nayak","year":"2023","unstructured":"Nayak VV et al (2023) Bone tissue engineering (BTE) of the craniofacial skeleton, Part I: evolution and optimization of 3D-printed scaffolds for repair of defects. J Craniofac Surg 34(7):2016\u20132025","journal-title":"J Craniofac Surg"},{"issue":"10","key":"10218_CR22","doi-asserted-by":"publisher","first-page":"E497","DOI":"10.1002\/term.1849","volume":"10","author":"SN Rath","year":"2016","unstructured":"Rath SN et al (2016) Adipose-and bone marrow-derived mesenchymal stem cells display different osteogenic differentiation patterns in 3D bioactive glass-based scaffolds. J Tissue Eng Regen Med 10(10):E497\u2013E509","journal-title":"J Tissue Eng Regen Med"},{"issue":"3","key":"10218_CR23","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.3390\/ma7031957","volume":"7","author":"U Rottensteiner","year":"2014","unstructured":"Rottensteiner U et al (2014) In vitro and in vivo biocompatibility of alginate dialdehyde\/gelatin hydrogels with and without nanoscaled bioactive glass for bone tissue engineering applications. Materials 7(3):1957\u20131974","journal-title":"Materials"},{"issue":"1","key":"10218_CR24","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/s12906-021-03284-4","volume":"21","author":"MS Salami","year":"2021","unstructured":"Salami MS et al (2021) Co-electrospun nanofibrous mats loaded with bitter gourd (Momordica charantia) extract as the wound dressing materials: in vitro and in vivo study. BMC Complement Med Ther 21(1):111","journal-title":"BMC Complement Med Ther"},{"issue":"113","key":"10218_CR25","doi-asserted-by":"publisher","first-page":"111908","DOI":"10.1039\/C6RA21596C","volume":"6","author":"H Samadian","year":"2016","unstructured":"Samadian H et al (2016) Effective parameters on conductivity of mineralized carbon nanofibers: an investigation using artificial neural networks. RSC Adv 6(113):111908\u2013111918","journal-title":"RSC Adv"},{"key":"10218_CR26","doi-asserted-by":"publisher","first-page":"78","DOI":"10.4028\/www.scientific.net\/JNanoR.50.78","volume":"50","author":"H Samadian","year":"2017","unstructured":"Samadian H et al (2017a) Needleless electrospinning system, an efficient platform to fabricate carbon nanofibers. J Nano Res 50:78\u201389","journal-title":"J Nano Res"},{"issue":"2","key":"10218_CR27","first-page":"87","volume":"2","author":"H Samadian","year":"2017","unstructured":"Samadian H et al (2017b) Electrospinning of polyacrylonitrile nanofibers and simulation of electric field via finite element method. Nanomed Res J 2(2):87\u201392","journal-title":"Nanomed Res J"},{"issue":"1","key":"10218_CR28","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1111\/prd.12413","volume":"88","author":"I Sanz\u2010S\u00e1nchez","year":"2022","unstructured":"Sanz\u2010S\u00e1nchez I et al (2022) Complications in bone\u2010grafting procedures: classification and management. Periodontol 2000 88(1):86\u2013102","journal-title":"Periodontol 2000"},{"issue":"5","key":"10218_CR29","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1021\/acs.biomac.2c00047","volume":"23","author":"Z Terzopoulou","year":"2022","unstructured":"Terzopoulou Z et al (2022) Biocompatible synthetic polymers for tissue engineering purposes. Biomacromol 23(5):1841\u20131863","journal-title":"Biomacromol"},{"issue":"2","key":"10218_CR30","doi-asserted-by":"publisher","first-page":"230","DOI":"10.3390\/cells10020230","volume":"10","author":"A Vall\u00e9e","year":"2021","unstructured":"Vall\u00e9e A, Vall\u00e9e J-N, Lecarpentier Y (2021a) Parkinson\u2019s disease: potential actions of lithium by targeting the WNT\/\u03b2-catenin pathway, oxidative stress, inflammation and glutamatergic pathway. Cells 10(2):230","journal-title":"Cells"},{"issue":"1","key":"10218_CR31","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1038\/s41398-021-01329-3","volume":"11","author":"A Vall\u00e9e","year":"2021","unstructured":"Vall\u00e9e A, Vall\u00e9e J-N, Lecarpentier Y (2021b) Lithium: a potential therapeutic strategy in obsessive\u2013compulsive disorder by targeting the canonical WNT\/\u03b2 pathway. Transl Psychiatry 11(1):204","journal-title":"Transl Psychiatry"},{"issue":"32","key":"10218_CR32","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202402073","volume":"9","author":"W Wang","year":"2024","unstructured":"Wang W et al (2024) MXene-based responsive hydrogels and applications in wound healing. ChemistrySelect 9(32):e202402073","journal-title":"ChemistrySelect"},{"key":"10218_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.compositesb.2025.112786","volume":"306","author":"K Xie","year":"2025","unstructured":"Xie K et al (2025) Additive manufacturing of cryogenic chemically complex alloys with sponge bone-like reticular nanoscale superstructure. Compos B Eng 306:112786","journal-title":"Compos B Eng"},{"issue":"3","key":"10218_CR34","doi-asserted-by":"publisher","first-page":"566","DOI":"10.3390\/polym14030566","volume":"14","author":"Y Xu","year":"2022","unstructured":"Xu Y et al (2022) Unraveling of advances in 3D-printed polymer-based bone scaffolds. Polymers 14(3):566","journal-title":"Polymers"},{"issue":"1","key":"10218_CR35","first-page":"100003","volume":"1","author":"Y Xu","year":"2025","unstructured":"Xu Y et al (2025) Orderly stacked 3D-nanohelices interlayer boosts performance of reverse osmosis membranes for effective water purification. Energy & Environ Sustain 1(1):100003","journal-title":"Energy & Environ Sustain"},{"key":"10218_CR36","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/B978-0-323-85488-7.00002-7","volume-title":"Additive manufacturing of glass","author":"K Zheng","year":"2025","unstructured":"Zheng K, Chen Q (2025) 3D printing of bioactive glasses and glass-ceramics for bone tissue regeneration. Additive manufacturing of glass. Elsevier, pp 187\u2013233"}],"container-title":["Cell and Tissue Banking"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10561-026-10218-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10561-026-10218-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10561-026-10218-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T22:04:39Z","timestamp":1780437879000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10561-026-10218-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,24]]},"references-count":36,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["10218"],"URL":"https:\/\/doi.org\/10.1007\/s10561-026-10218-2","relation":{},"ISSN":["1573-6814"],"issn-type":[{"value":"1573-6814","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,24]]},"assertion":[{"value":"30 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}},{"value":"Ethical consideration related to the study was approved by the Research Ethics Committee of Hamadan University of Medical Science (IR.UMSHA.AEC.1403.007).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"18"}}