{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T05:35:13Z","timestamp":1790487313265,"version":"4.1.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,9,28]],"date-time":"2013-09-28T00:00:00Z","timestamp":1380326400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Mol Neurobiol"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1007\/s10571-013-9990-z","type":"journal-article","created":{"date-parts":[[2013,9,27]],"date-time":"2013-09-27T11:49:55Z","timestamp":1380282595000},"page":"95-100","source":"Crossref","is-referenced-by-count":7,"title":["Prednisolone Induces Microglial Activation in the Subnucleus Caudalis of the Rat Trigeminal Sensory Complex"],"prefix":"10.1007","volume":"34","author":[{"given":"Yu","family":"Endo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Shoji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eriko","family":"Kasahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Iikubo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadasu","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Sasano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Ichikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,9,28]]},"reference":[{"key":"9990_CR1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1002\/cne.20272","volume":"478","author":"YC Bae","year":"2004","unstructured":"Bae YC, Oh JM, Hwang SJ, Shigenaga Y, Valtschanoff JG (2004) Expression of vanilloid receptor TRPV1 in the rat trigeminal sensory nuclei. J Comp Neurol 478:62\u201371","journal-title":"J Comp Neurol"},{"key":"9990_CR2","first-page":"301","volume":"64","author":"B Bannwarth","year":"1997","unstructured":"Bannwarth B, Schaeverbeke T, P\u00e9hourcq F, Vernhes JP, D\u2019Yvoire MB, Dehais J (1997) Prednisolone concentrations in cerebrospinal fluid after oral prednisone. Preliminary data. Rev Rhum Engl Ed 64:301\u2013304","journal-title":"Rev Rhum Engl Ed"},{"key":"9990_CR3","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/39807","volume":"389","author":"MJ Caterina","year":"1997","unstructured":"Caterina MJ, Schumacher MA, Tominaga, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816\u2013824","journal-title":"Nature"},{"key":"9990_CR4","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/0306-4522(94)90481-2","volume":"62","author":"A Cintra","year":"1994","unstructured":"Cintra A, Zoli M, Ros\u00e9n L, Agnati LF, Okret S, Wikstr\u00f6m AC, Gustaffsson JA, Fuxe K (1994) Mapping and computer assisted morphometry and microdensitometry of glucocorticoid receptor immunoreactive neurons and glial cells in the rat central nervous system. Neuroscience 62:843\u2013897","journal-title":"Neuroscience"},{"key":"9990_CR5","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/0006-8993(94)91034-0","volume":"636","author":"M DeLe\u00f3n","year":"1994","unstructured":"DeLe\u00f3n M, Cove\u00f1as R, Chadi G, Narv\u00e1ez JA, Fuxe K, Cintra A (1994) Subpopulations of primary sensory neurons show coexistence of neuropeptides and glucocorticoid receptors in the rat spinal and trigeminal ganglia. Brain Res 636:338\u2013342","journal-title":"Brain Res"},{"key":"9990_CR6","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/S0169-328X(98)00297-6","volume":"63","author":"T Fukuoka","year":"1999","unstructured":"Fukuoka T, Tokunaga A, Kondo E, Miki K, Tachibana T, Noguchi K (1999) Differential regulation of alpha- and beta-CGRP mRNAs within oculomotor, trochlear, abducens, and trigeminal motoneurons in response to axotomy. Brain Res Mol Brain Res 63:304\u2013315","journal-title":"Brain Res Mol Brain Res"},{"key":"9990_CR7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0304-3940(85)90372-6","volume":"60","author":"K Fuxe","year":"1985","unstructured":"Fuxe K, H\u00e4rfstrand A, Agnati LF, Yu ZY, Cintra A, Wikstr\u00f6m AC, Okret S, Cantoni E, Gustafsson JA (1985) Immunocytochemical studies on the localization of glucocorticoid receptor immunoreactive nerve cells in the lower brain stem and spinal cord of the male rat using a monoclonal antibody against rat liver glucocorticoid receptor. Neurosci Lett 60:1\u20136","journal-title":"Neurosci Lett"},{"key":"9990_CR8","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0065-1281(11)80334-X","volume":"94","author":"C Grothe","year":"1993","unstructured":"Grothe C (1993) Biphasic increase of calcitonin gene-related peptide-like immunoreactivity in rat hypoglossal motoneurons after nerve transection. Acta Histochem 94:20\u201324","journal-title":"Acta Histochem"},{"key":"9990_CR9","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0306-4522(01)00070-7","volume":"104","author":"LE Haynes","year":"2001","unstructured":"Haynes LE, Griffiths MR, Hyde RE, Barber DJ, Mitchell IJ (2001) Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders. Neuroscience 104:57\u201369","journal-title":"Neuroscience"},{"key":"9990_CR10","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/s00018-005-5390-y","volume":"63","author":"MJ Herold","year":"2006","unstructured":"Herold MJ, McPherson KG, Reichardt HM (2006) Glucocorticoids in T cell apoptosis and function. Cell Mol Life Sci 63:60\u201372","journal-title":"Cell Mol Life Sci"},{"key":"9990_CR11","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0006-8993(00)03253-4","volume":"890","author":"H Ichikawa","year":"2001","unstructured":"Ichikawa H, Sugimoto T (2001) VR1-immunoreactive primary sensory neurons in the rat trigeminal ganglion. Brain Res 890:184\u2013188","journal-title":"Brain Res"},{"key":"9990_CR12","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s10571-011-9648-7","volume":"31","author":"H Ichikawa","year":"2011","unstructured":"Ichikawa H, Sato T, Kano M, Suzuki T, Matsuo S, Kanetaka H, Shimizu Y (2011) Masseteric nerve injury increases expression of brain-derived neurotrophic factor in microglia within the rat mesencephalic trigeminal tract nucleus. Cell Mol Neurobiol 31:551\u2013559","journal-title":"Cell Mol Neurobiol"},{"key":"9990_CR13","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0165-5728(91)90119-R","volume":"34","author":"R Kiefer","year":"1991","unstructured":"Kiefer R, Kreutzberg GW (1991) Effects of dexamethasone on microglial activation in vivo: selective downregulation of major histocompatibility complex class II expression in regenerating facial nucleus. J Neuroimmunol 34:99\u2013108","journal-title":"J Neuroimmunol"},{"key":"9990_CR14","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1097\/WNR.0b013e3283546242","volume":"23","author":"T Kuroi","year":"2012","unstructured":"Kuroi T, Shimizu T, Shibata M, Toriumi H, Funakubo M, Iwashita T, Sato H, Koizumi K, Suzuki N (2012) Alterations in microglia and astrocytes in the trigeminal nucleus caudalis by repetitive TRPV1 stimulation on the trigeminal nociceptors. NeuroReport 23:560\u2013565","journal-title":"NeuroReport"},{"key":"9990_CR15","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/BF00179953","volume":"253","author":"R Laskawi","year":"1996","unstructured":"Laskawi R, Wolff JR (1996) Changes in glial fibrillary acidic protein immunoreactivity in the rat facial nucleus following various types of nerve lesions. Eur Arch Otorhinolaryngol 253:475\u2013480","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"9990_CR16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/1744-8069-6-79","volume":"6","author":"S Lee","year":"2010","unstructured":"Lee S, Zhao YQ, Ribeiro-da-Silva A, Zhang J (2010) Distinctive response of CNS glial cells in oro-facial pain associated with injury, infection and inflammation. Mol Pain 6:79","journal-title":"Mol Pain"},{"key":"9990_CR17","doi-asserted-by":"crossref","first-page":"226","DOI":"10.5115\/acb.2011.44.3.226","volume":"44","author":"BG Park","year":"2011","unstructured":"Park BG, Lee JS, Lee JY, Song DY, Jeong SW, Cho BP (2011) Co-localization of activating transcription factor 3 and phosphorylated c-Jun in axotomized facial motoneurons. Anat Cell Biol 44:226\u2013237","journal-title":"Anat Cell Biol"},{"key":"9990_CR18","doi-asserted-by":"crossref","first-page":"458","DOI":"10.2310\/6650.2002.32536","volume":"50","author":"C Ramos-Remus","year":"2002","unstructured":"Ramos-Remus C, Gonz\u00e1lez-Casta\u00f1eda RE, Gonz\u00e1lez-Perez O, Luquin S, Garc\u00eda-Estrada J (2002) Prednisone induces cognitive dysfunction, neuronal degeneration, and reactive gliosis in rats. J Investig Med 50:458\u2013464","journal-title":"J Investig Med"},{"key":"9990_CR19","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1213\/01.ANE.0000180206.95542.76","volume":"101","author":"S Schubert","year":"2005","unstructured":"Schubert S, Stoltenburg-Didinger G, Wehsack A, Troitzsch D, Boettcher W, Huebler M, Redlin M, Kanaan M, Meissler M, Lange PE, Abdul-Khaliq H (2005) Large-dose pretreatment with methylprednisolone fails to attenuate neuronal injury after deep hypothermic circulatory arrest in a neonatal piglet model. Anesth Analg 101:1311\u20131318","journal-title":"Anesth Analg"},{"key":"9990_CR20","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0304-3940(89)90521-1","volume":"101","author":"WJ Streit","year":"1989","unstructured":"Streit WJ, Dumoulin FL, Raivich G, Kreutzberg GW (1989) Calcitonin gene-related peptide increases in rat facial motoneurons after peripheral nerve transection. Neurosci Lett 101:143\u2013148","journal-title":"Neurosci Lett"},{"key":"9990_CR21","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1007\/s10517-010-1048-3","volume":"149","author":"EG Suchorukova","year":"2010","unstructured":"Suchorukova EG, Kirik OV, Korzhevskii DE (2010) The use of immunohistochemical method for detection of brain microglia in paraffin sections. Bull Exp Biol Med 149:768\u2013770","journal-title":"Bull Exp Biol Med"},{"key":"9990_CR22","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/(SICI)1096-9861(19970217)378:3<425::AID-CNE9>3.0.CO;2-5","volume":"378","author":"T Sugimoto","year":"1997","unstructured":"Sugimoto T, Fujiyoshi Y, Xiao C, He YF, Ichikawa H (1997) Central projection of calcitonin gene-related peptide (CGRP)- and substance P (SP)-immunoreactive trigeminal primary neurons in the rat. J Comp Neurol 378:425\u2013442","journal-title":"J Comp Neurol"},{"key":"9990_CR23","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.brainres.2004.05.069","volume":"1017","author":"T Sugimoto","year":"2004","unstructured":"Sugimoto T, Jin H, Fijita M, Fukunaga T, Nagaoka N, Yamaai T, Ichikawa H (2004) Induction of activated caspase-3-immunoreactivity and apoptosis in the trigeminal ganglion neurons by neonatal peripheral nerve injury. Brain Res 1017:238\u2013243","journal-title":"Brain Res"},{"key":"9990_CR24","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0304-3940(02)00349-X","volume":"326","author":"CK Tan","year":"2002","unstructured":"Tan CK, Yan J, Ananth C, Kaur C (2002) Dexamethasone induces dendritic alteration but not apoptosis in the neurons of the hippocampus in postnatal rats. Neurosci Lett 326:206\u2013210","journal-title":"Neurosci Lett"},{"key":"9990_CR25","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.neures.2010.11.004","volume":"69","author":"R Terayama","year":"2011","unstructured":"Terayama R, Fujisawa N, Yamaguchi D, Omura S, Ichikawa H, Sugimoto T (2011) Differential activation of mitogen-activated protein kinases and glial cells in the trigeminal sensory nuclear complex following lingual nerve injury. Neurosci Res 69:100\u2013110","journal-title":"Neurosci Res"},{"key":"9990_CR26","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0304-3959(00)00456-5","volume":"91","author":"K Tsuzuki","year":"2001","unstructured":"Tsuzuki K, Kondo E, Fukuoka T, Yi D, Tsujino H, Sakagami M, Noguchi K (2001) Differential regulation of P2X(3) mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia. Pain 91:351\u2013360","journal-title":"Pain"},{"key":"9990_CR27","doi-asserted-by":"crossref","first-page":"3469","DOI":"10.1046\/j.1460-9568.2000.00241.x","volume":"12","author":"JL Vanderluit","year":"2000","unstructured":"Vanderluit JL, McPhail LT, Fernandes KJ, McBride CB, Huguenot C, Roy S, Robertson GS, Nicholson DW, Tetzlaff W (2000) Caspase-3 is activated following axotomy of neonatal facial motoneurons and caspase-3 gene deletion delays axotomy-induced cell death in rodents. Eur J Neurosci 12:3469\u20133480","journal-title":"Eur J Neurosci"},{"key":"9990_CR28","doi-asserted-by":"crossref","first-page":"3974","DOI":"10.1523\/JNEUROSCI.4363-08.2009","volume":"29","author":"H Wake","year":"2009","unstructured":"Wake H, Moorhouse AJ, Jinno S, Kohsaka S, Nabekura J (2009) Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J Neurosci 29:3974\u20133980","journal-title":"J Neurosci"}],"container-title":["Cellular and Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10571-013-9990-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10571-013-9990-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10571-013-9990-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T18:10:17Z","timestamp":1559239817000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10571-013-9990-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,28]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["9990"],"URL":"https:\/\/doi.org\/10.1007\/s10571-013-9990-z","relation":{},"ISSN":["0272-4340","1573-6830"],"issn-type":[{"value":"0272-4340","type":"print"},{"value":"1573-6830","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,28]]}}}