{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T03:53:23Z","timestamp":1793246003186,"version":"4.5.0"},"reference-count":206,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T00:00:00Z","timestamp":1753488000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T00:00:00Z","timestamp":1753488000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100009367","name":"Mansoura University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009367","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cell Mol Neurobiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Recent developments in neural circuit mapping and neurotherapy are changing our understanding of the dynamic network structure of the brain and offering new treatment options. In many neurological and psychiatric diseases, targeted control of specific brain circuits has proven to be a successful strategy to reduce cognitive, behavioral, and motor abnormalities. Sophisticated retrograde tracing techniques, transcranial magnetic stimulation (TMS), chemogenetics, optogenetics, and other technologies have greatly improved our ability to outline, observe, and control neuronal circuits with remarkable accuracy. These sophisticated techniques have revealed crucial information on neuroplasticity, circuit remodeling following injury, and the therapeutic potential of neuromodulatory interventions. Disorders include depression, anxiety, stroke, and neurodegenerative diseases are treated using techniques such as optogenetic stimulation, chemogenetic activation, and non-invasive brain stimulation to restore circuit function. Emerging multifunctional probes like Tetracysteine Display of Optogenetic Elements (Tetro-DOpE) provide real-time monitoring and modification of neuronal populations, improving circuit-level interventions\u2019 precision. At the same time, especially following severe brain injury and neurodegeneration, stem cell treatments combined with neurogenesis-promoting strategies show great promise in increasing circuit repair and functional recovery. The development of drug delivery methods like tailored nanoparticle systems and multifunctional probes is helping to improve the accuracy and safety of treatments by reducing off-target effects. These developments taken together draw attention to a notable shift toward precision neuromedicine. These techniques are meant to offer more efficient, focused, and specialized treatments for various neurological and psychiatric diseases by combining sophisticated circuit mapping with tailored therapeutic interventions.<\/jats:p>","DOI":"10.1007\/s10571-025-01595-5","type":"journal-article","created":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T06:18:18Z","timestamp":1753510698000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Neural Circuit Mapping and Neurotherapy-Based Strategies"],"prefix":"10.1007","volume":"45","author":[{"given":"Hany E.","family":"Marei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,26]]},"reference":[{"issue":"1","key":"1595_CR1","first-page":"39","volume":"35","author":"JB Aimone","year":"2014","unstructured":"Aimone JB et al (2014) Adult neurogenesis and cognitive flexibility. Neurobiol Aging 35(1):39\u201349","journal-title":"Neurobiol Aging"},{"key":"1595_CR2","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1146\/annurev.ne.09.030186.002041","volume":"9","author":"GE Alexander","year":"1986","unstructured":"Alexander GE, DeLong MR, Strick PL (1986) Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9:357\u2013381","journal-title":"Annu Rev Neurosci"},{"issue":"7614","key":"1595_CR3","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1038\/nature18944","volume":"536","author":"TM Anderson","year":"2016","unstructured":"Anderson TM, Garcia AJ III, Baertsch NA et al (2016) A novel excitatory network for the control of breathing. Nature 536(7614):76\u201380","journal-title":"Nature"},{"issue":"22","key":"1595_CR4","doi-asserted-by":"publisher","first-page":"12605","DOI":"10.3390\/ijms222212605","volume":"22","author":"F Antonelli","year":"2021","unstructured":"Antonelli F, Casciati A, Belles M, Serra N, Linares-Vidal MV, Marino C et al (2021) Long-term effects of ionizing radiation on the hippocampus: linking effects of the sonic hedgehog pathway activation with radiation response. Int J Mol Sci 22(22):12605","journal-title":"Int J Mol Sci"},{"issue":"1","key":"1595_CR5","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1001\/archneur.59.1.102","volume":"59","author":"H Apaydin","year":"2002","unstructured":"Apaydin H, Ahlskog JE, Parisi JE, Boeve BF, Dickson DW (2002) Parkinson disease neuropathology: later-developing dementia and loss of dopaminergic neurons in the substantia nigra. Arch Neurol 59(1):102\u2013107","journal-title":"Arch Neurol"},{"key":"1595_CR6","first-page":"823745","volume":"14","author":"M Au","year":"2023","unstructured":"Au M et al (2023) Neuropsychiatric benefits of GLP-1 receptor agonists: Insights from type 2 diabetes and obesity treatment. Front Pharmacol 14:823745","journal-title":"Front Pharmacol"},{"key":"1595_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2024.11.019","author":"HC Au","year":"2024","unstructured":"Au HC, Zheng YJ, Le GH, Wong S, Phan L, Teopiz KM, Kwan AT, Rhee TG, Rosenblat JD, Ho R, McIntyre RS (2024) A systematic review in effects of glucagon-like peptide-1 (GLP-1) mono-agonists on functional connectivity: target engagement and rationale for the development in mental disorders. J Affect Disorders. https:\/\/doi.org\/10.1016\/j.jad.2024.11.019","journal-title":"J Affect Disorders"},{"key":"1595_CR8","first-page":"108956","volume":"205","author":"J B\u00e4ckman","year":"2023","unstructured":"B\u00e4ckman J et al (2023) GLP-1 receptor agonists and neurodegenerative diseases: a review of the neuroprotective mechanisms in AD. Neuropharmacology 205:108956","journal-title":"Neuropharmacology"},{"key":"1595_CR9","doi-asserted-by":"publisher","DOI":"10.1113\/JP286205","author":"G Balbinot","year":"2024","unstructured":"Balbinot G et al (2024) The mechanisms of electrical neuromodulation. J Physiol. https:\/\/doi.org\/10.1113\/JP286205","journal-title":"J Physiol"},{"key":"1595_CR10","first-page":"272","volume":"10","author":"EL Barbier","year":"2016","unstructured":"Barbier EL et al (2016) Neurogenesis in the hippocampus: a potential therapeutic target for neurodegenerative diseases. Front Neurosci 10:272","journal-title":"Front Neurosci"},{"key":"1595_CR11","doi-asserted-by":"crossref","first-page":"947","DOI":"10.3389\/fneur.2020.00947","volume":"11","author":"P Barbosa","year":"2020","unstructured":"Barbosa P, Valente AR, Freire S, Firmino H, Santana I (2020) Basal ganglia atrophy in Alzheimer\u2019s disease: a systematic review. Front Neurol 11:947","journal-title":"Front Neurol"},{"key":"1595_CR12","doi-asserted-by":"publisher","first-page":"110389","DOI":"10.1016\/j.yebeh.2025.110389","volume":"167","author":"ZL Bernstein","year":"2025","unstructured":"Bernstein ZL, Raghu AL, Zand APD, Kheder A, Gross RE (2025) Long-term seizure reduction in generalized epilepsy after anterior nucleus of the thalamus stimulation. Epilepsy Behav 167:110389","journal-title":"Epilepsy Behav"},{"issue":"5","key":"1595_CR13","first-page":"750","volume":"15","author":"AW Bero","year":"2012","unstructured":"Bero AW et al (2012) Neuronal activity regulates the regional vulnerability to amyloid-\u03b2 deposition. Nat Neurosci 15(5):750\u2013756","journal-title":"Nat Neurosci"},{"key":"1595_CR14","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.bbi.2024.09.001","volume":"123","author":"R Bose","year":"2025","unstructured":"Bose R et al (2025) Bi-allelic NRXN1\u03b1 deletion in microglia derived from iPSC of an autistic patient increases interleukin-6 production and impairs supporting function on neuronal networking. Brain Behav Immun 123:28\u201342","journal-title":"Brain Behav Immun"},{"key":"1595_CR15","first-page":"1","volume":"16","author":"AK Brem","year":"2022","unstructured":"Brem AK et al (2022) Personalized neuromodulation for psychiatric disorders: integrating functional connectivity mapping with tDCS protocols. Front Hum Neurosci 16:1\u201314","journal-title":"Front Hum Neurosci"},{"key":"1595_CR16","doi-asserted-by":"publisher","DOI":"10.1177\/20494637241311784","author":"AB Brennecke","year":"2025","unstructured":"Brennecke AB et al (2025) Impact of different treatments for chronic pain on cognitive function: a systematic review. Br J Pain. https:\/\/doi.org\/10.1177\/20494637241311784","journal-title":"Br J Pain"},{"issue":"8","key":"1595_CR17","first-page":"398","volume":"21","author":"MA Busche","year":"2020","unstructured":"Busche MA, Hyman BT (2020) Synergy between amyloid-\u03b2 and tau in AD. Nat Rev Neurosci 21(8):398\u2013414","journal-title":"Nat Rev Neurosci"},{"issue":"1","key":"1595_CR18","doi-asserted-by":"crossref","first-page":"5556","DOI":"10.1038\/s41467-023-41340-4","volume":"14","author":"X Cai","year":"2023","unstructured":"Cai X et al (2023) Optogenetic restoration of hippocampal network coherence reverses memory deficits in AD mice. Nat Commun 14(1):5556","journal-title":"Nat Commun"},{"issue":"9","key":"1595_CR19","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/nbt.4222","volume":"36","author":"A Canales","year":"2018","unstructured":"Canales A, Park S, Kilias A et al (2018) Multifunctional fibers for simultaneous optical, electrical, and chemical interrogation of neural circuits in vivo. Nat Biotechnol 36(9):857\u2013864","journal-title":"Nat Biotechnol"},{"issue":"5","key":"1595_CR20","doi-asserted-by":"crossref","first-page":"056001","DOI":"10.1088\/1741-2552\/acf345","volume":"20","author":"F Capone","year":"2023","unstructured":"Capone F et al (2023) Transcutaneous auricular vagus nerve stimulation and cholinergic brain networks: a human study. J Neural Eng 20(5):056001","journal-title":"J Neural Eng"},{"key":"1595_CR21","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.clinph.2024.11.012","volume":"169","author":"F Capone","year":"2025","unstructured":"Capone F et al (2025) The effects of transcutaneous auricular vagus nerve stimulation (taVNS) on cholinergic neural networks in humans: a neurophysiological study. Clin Neurophysiol 169:47\u201352","journal-title":"Clin Neurophysiol"},{"issue":"10","key":"1595_CR22","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1016\/j.tins.2018.07.015","volume":"41","author":"JA Cardin","year":"2018","unstructured":"Cardin JA (2018) Inhibitory interneurons regulate temporal precision and correlations in cortical circuits. Trends Neurosci 41(10):689\u2013700","journal-title":"Trends Neurosci"},{"key":"1595_CR23","doi-asserted-by":"publisher","first-page":"46","DOI":"10.3389\/fnbeh.2014.00046","volume":"8","author":"DK Cass","year":"2014","unstructured":"Cass DK, Flores-Barrera E, Thomases DR, Vital WF, Caballero A, Tseng KY (2014) Adolescent development of endocannabinoid signaling and its role in the adult prefrontal cortex: a critical period of plasticity. Front Behav Neurosci 8:46. https:\/\/doi.org\/10.3389\/fnbeh.2014.00046","journal-title":"Front Behav Neurosci"},{"key":"1595_CR24","doi-asserted-by":"publisher","first-page":"23","DOI":"10.4103\/NRR.NRR-D-24-01035","volume":"21","author":"Y Chen","year":"2016","unstructured":"Chen Y et al (2016) Epilepsy therapy beyond neurons: unveiling astrocytes as cellular targets. Neural Regener Res 21:23\u201338","journal-title":"Neural Regener Res"},{"issue":"5","key":"1595_CR25","doi-asserted-by":"publisher","first-page":"106703","DOI":"10.1016\/j.isci.2023.106703","volume":"26","author":"L Chen","year":"2023","unstructured":"Chen L et al (2023) Anatomical organization of temporally correlated neural calcium activity in the hippocampal CA1 region. Iscience 26(5):106703","journal-title":"Iscience"},{"issue":"2","key":"1595_CR26","first-page":"e13547","volume":"32","author":"X Chen","year":"2023","unstructured":"Chen X et al (2023a) Olfactory pathways and their involvement in sleep regulation: a comprehensive review. J Sleep Res 32(2):e13547","journal-title":"J Sleep Res"},{"issue":"7","key":"1595_CR27","first-page":"eade1507","volume":"9","author":"WT Chen","year":"2023","unstructured":"Chen WT et al (2023b) Spatially resolved transcriptomics reveals associated\u2013\u03b2\u2013amyloid inflammatory and synaptic dysfunction pathways in AD. Sci Adv 9(7):eade1507","journal-title":"Sci Adv"},{"issue":"2","key":"1595_CR28","first-page":"496","volume":"32","author":"G Chen","year":"2024","unstructured":"Chen G et al (2024a) AAV-delivered bispecific antibodies targeting amyloid-\u03b2 reduce pathology in AD mouse models. Mol Ther 32(2):496\u2013508","journal-title":"Mol Ther"},{"issue":"4","key":"1595_CR29","doi-asserted-by":"publisher","first-page":"103470","DOI":"10.1016\/j.xpro.2024.103470","volume":"5","author":"Y Chen","year":"2024","unstructured":"Chen Y et al (2024b) Protocol for chemogenetic activation of basal ganglia D1-MSNs and behavioral assessments in a primate PD model. STAR Protocols 5(4):103470","journal-title":"STAR Protocols"},{"issue":"1","key":"1595_CR30","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.biopsych.2016.07.002","volume":"81","author":"N Chuhma","year":"2017","unstructured":"Chuhma N et al (2017) Heterogeneity in dopamine neuron synaptic actions across the striatum and its relevance for schizophrenia. Biol Psychiat 81(1):43\u201351","journal-title":"Biol Psychiat"},{"issue":"8","key":"1595_CR31","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1176\/appi.ajp.2019.19070720","volume":"177","author":"EJ Cole","year":"2020","unstructured":"Cole EJ, Stimpson KH, Bentzley BS, Gulser M, Cherian K, Tischler C et al (2020) Stanford accelerated intelligent neuromodulation therapy for treatment-resistant depression. Am J Psychiatry 177(8):716\u2013726","journal-title":"Am J Psychiatry"},{"issue":"1","key":"1595_CR32","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1186\/s13063-024-08629-1","volume":"25","author":"C Conelea","year":"2024","unstructured":"Conelea C et al (2024) The NExT trial: protocol for a two-phase randomized controlled trial testing transcranial magnetic stimulation to augment exposure therapy for youth with OCD. Trials 25(1):835","journal-title":"Trials"},{"issue":"2","key":"1595_CR33","first-page":"102","volume":"91","author":"D Datta","year":"2022","unstructured":"Datta D, Arnsten AFT, Gordon JA (2022) Dysfunction of prefrontal cortex circuits in schizophrenia: recent advances and therapeutic implications. Biol Psychiat 91(2):102\u2013114","journal-title":"Biol Psychiat"},{"issue":"6","key":"1595_CR34","first-page":"1211","volume":"172","author":"A Deczkowska","year":"2018","unstructured":"Deczkowska A, Weiner A, Amit I (2018) The physiology, pathology, and potential therapeutic applications of the TREM2 signaling pathway. Cell 172(6):1211\u20131225","journal-title":"Cell"},{"issue":"1","key":"1595_CR35","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1038\/nmeth.f.324","volume":"8","author":"K Deisseroth","year":"2011","unstructured":"Deisseroth K (2011) Optogenetics. Nat Methods 8(1):26\u201329. https:\/\/doi.org\/10.1038\/nmeth.f.324","journal-title":"Nat Methods"},{"issue":"7851","key":"1595_CR36","first-page":"185","volume":"591","author":"K Deisseroth","year":"2021","unstructured":"Deisseroth K (2021) Circuit dynamics of adaptive and maladaptive behavior. Nature 591(7851):185\u2013191","journal-title":"Nature"},{"key":"1595_CR37","doi-asserted-by":"publisher","DOI":"10.1007\/7854_2024_547","author":"DE D\u00edaz","year":"2024","unstructured":"D\u00edaz DE, Becker HC, Fitzgerald KD (2024) Neural markers of treatment response in pediatric anxiety and PTSD. Curr Top Behav Neurosci. https:\/\/doi.org\/10.1007\/7854_2024_547","journal-title":"Curr Top Behav Neurosci"},{"issue":"48","key":"1595_CR38","doi-asserted-by":"publisher","first-page":"e1367242024","DOI":"10.1523\/JNEUROSCI.1367-24.2024","volume":"44","author":"JC Dooley","year":"2024","unstructured":"Dooley JC, van der Heijden ME (2024) More than a small brain: the importance of studying neural function during development. J Neurosci 44(48):e1367242024","journal-title":"J Neurosci"},{"key":"1595_CR39","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/S0079-6123(07)63041-6","volume":"163","author":"SM Dudek","year":"2007","unstructured":"Dudek SM, Sutula TP (2007) Epileptogenesis in the dentate gyrus: a critical perspective. Prog Brain Res 163:755\u2013773","journal-title":"Prog Brain Res"},{"key":"1595_CR40","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1146\/annurev-psych-010416-044131","volume":"68","author":"H Eichenbaum","year":"2017","unstructured":"Eichenbaum H (2017) Memory: organization and control. Annu Rev Psychol 68:19\u201345. https:\/\/doi.org\/10.1146\/annurev-psych-010416-044131","journal-title":"Annu Rev Psychol"},{"key":"1595_CR41","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1038\/s41586-024-08145-x","volume":"636","author":"M El-Gaby","year":"2024","unstructured":"El-Gaby M et al (2024a) A cellular basis for mapping behavioural structure. Nature 636:671\u2013680","journal-title":"Nature"},{"issue":"1","key":"1595_CR43","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1186\/s40478-024-01906-9","volume":"12","author":"SM El-Khatib","year":"2024","unstructured":"El-Khatib SM et al (2024) BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences. Acta Neuropathol Commun 12(1):190","journal-title":"Acta Neuropathol Commun"},{"key":"1595_CR44","first-page":"659888","volume":"15","author":"DF English","year":"2021","unstructured":"English DF, Venance L (2021) Targeting basal ganglia circuits in PD: from optogenetics to chemogenetics. Front Neural Circ 15:659888","journal-title":"Front Neural Circ"},{"issue":"6301","key":"1595_CR500","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1126\/science.aag3194","volume":"353","author":"ML Estes","year":"2016","unstructured":"Estes ML, McAllister AK (2016) Maternal immune activation: implications for neuropsychiatric disorders. Science 353(6301):772\u2013777","journal-title":"Science"},{"issue":"5853","key":"1595_CR45","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1126\/science.1148979","volume":"318","author":"DR Euston","year":"2007","unstructured":"Euston DR, Tatsuno M, McNaughton BL (2007) Fast-forward playback of recent memory sequences in prefrontal cortex during sleep. Science 318(5853):1147\u20131150. https:\/\/doi.org\/10.1126\/science.1148979","journal-title":"Science"},{"issue":"7","key":"1595_CR46","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/j.tins.2008.04.001","volume":"31","author":"RD Fields","year":"2008","unstructured":"Fields RD (2008) White matter in learning, cognition and psychiatric disorders. Trends Neurosci 31(7):361\u2013370. https:\/\/doi.org\/10.1016\/j.tins.2008.04.001","journal-title":"Trends Neurosci"},{"key":"1595_CR47","unstructured":"Fineman JB (2020) The basal ganglia and related structures: functional neuroanatomy and clinical implications. In Chun MM, Greene JD, Roskies BR (eds) The cognitive neurosciences, 6th edn. MIT Press, pp 435\u2013446"},{"issue":"6","key":"1595_CR48","first-page":"910","volume":"44","author":"X Geng","year":"2024","unstructured":"Geng X et al (2024) Stem cell transplantation for neurogenesis and functional recovery in ischemic stroke. J Cereb Blood Flow Metab 44(6):910\u2013923","journal-title":"J Cereb Blood Flow Metab"},{"key":"1595_CR50","first-page":"695539","volume":"12","author":"RC Gershon","year":"2021","unstructured":"Gershon RC et al (2021) Personalized neuromodulation approaches in neurological disorders: Moving towards precision medicine. Front Neurol 12:695539","journal-title":"Front Neurol"},{"issue":"3","key":"1595_CR51","first-page":"422","volume":"49","author":"S Ghosh","year":"2022","unstructured":"Ghosh S et al (2022) Cholinergic dysfunction in neurological diseases: Implications for vagus nerve stimulation. Brain Res Rev 49(3):422\u2013435","journal-title":"Brain Res Rev"},{"key":"1595_CR52","first-page":"1","volume-title":"Brain organoid research","author":"SL Giandomenico","year":"2022","unstructured":"Giandomenico SL, Lancaster MA (2022) Self-organizing brain organoids with ventricles amenable to injection and electroporation. Brain organoid research. Springer, New York, pp 1\u201316"},{"issue":"5925","key":"1595_CR53","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1126\/science.1167093","volume":"324","author":"V Gradinaru","year":"2010","unstructured":"Gradinaru V et al (2010) Optical deconstruction of parkinsonian neural circuitry. Science 324(5925):354\u2013359","journal-title":"Science"},{"issue":"12","key":"1595_CR54","doi-asserted-by":"publisher","first-page":"5293","DOI":"10.1038\/s41380-023-02153-5","volume":"28","author":"SF Grieco","year":"2023","unstructured":"Grieco SF et al (2023a) Anatomical and molecular characterization of parvalbumin-cholecystokinin co-expressing inhibitory interneurons: implications for neuropsychiatric conditions. Mol Psychiatry 28(12):5293\u20135308","journal-title":"Mol Psychiatry"},{"issue":"10","key":"1595_CR55","doi-asserted-by":"publisher","first-page":"4021","DOI":"10.1038\/s41380-023-02393-5","volume":"28","author":"SF Grieco","year":"2023","unstructured":"Grieco SF, Holmes TC, Xu X (2023b) Monosynaptic rabies tracing maps inputs to CA1 cells in old AD model mice (APP-KI). Mol Psychiatry 28(10):4021\u20134021","journal-title":"Mol Psychiatry"},{"issue":"10","key":"1595_CR56","doi-asserted-by":"publisher","first-page":"4407","DOI":"10.1038\/s41380-023-02018-x","volume":"28","author":"SF Grieco","year":"2023","unstructured":"Grieco SF, Holmes TC, Xu X (2023c) Probing neural circuit mechanisms in AD using novel technologies. Mol Psychiatry 28(10):4407\u20134420","journal-title":"Mol Psychiatry"},{"key":"1595_CR57","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.neurobiolaging.2015.12.003","volume":"39","author":"MJ Grothe","year":"2016","unstructured":"Grothe MJ, Heinsen H, Teipel SJ (2016) Longitudinal measures of cholinergic forebrain atrophy predict cognitive decline in Alzheimer\u2019s disease. Neurobiol Aging 39:118\u2013126","journal-title":"Neurobiol Aging"},{"issue":"9","key":"1595_CR58","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1038\/nn.4601","volume":"20","author":"T Gulati","year":"2017","unstructured":"Gulati T, Guo L, Ramanathan DS, Bodepudi A, Ganguly K (2017) Neural reactivations during sleep determine network credit assignment. Nat Neurosci 20(9):1277\u20131284. https:\/\/doi.org\/10.1038\/nn.4601","journal-title":"Nat Neurosci"},{"issue":"26","key":"1595_CR59","doi-asserted-by":"publisher","first-page":"8586","DOI":"10.1523\/JNEUROSCI.1868-09.2009","volume":"29","author":"C Habas","year":"2009","unstructured":"Habas C, Kamdar N, Nguyen D et al (2009) Distinct cerebellar contributions to intrinsic connectivity networks. J Neurosci 29(26):8586\u20138594","journal-title":"J Neurosci"},{"issue":"1","key":"1595_CR60","doi-asserted-by":"publisher","first-page":"7","DOI":"10.31887\/DCNS.2016.18.1\/shaber","volume":"18","author":"SN Haber","year":"2016","unstructured":"Haber SN (2016) Corticostriatal circuitry. Dialogues Clin Neurosci 18(1):7\u201321","journal-title":"Dialogues Clin Neurosci"},{"key":"1595_CR61","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1038\/s41380-024-02669-4","volume":"30","author":"J Hagen","year":"2024","unstructured":"Hagen J et al (2024) Phenomena of hypo-and hyperconnectivity in basal ganglia-thalamo-cortical circuits linked to major depression: a 7T fMRI study. Mol Psychiatry 30:158\u2013167","journal-title":"Mol Psychiatry"},{"issue":"4","key":"1595_CR62","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1016\/j.immuni.2019.03.009","volume":"50","author":"TR Hammond","year":"2019","unstructured":"Hammond TR, Marsh SE, Stevens B (2019) Immune signaling in neurodegeneration. Immunity 50(4):955\u2013974. https:\/\/doi.org\/10.1016\/j.immuni.2019.03.009","journal-title":"Immunity"},{"key":"1595_CR63","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.brainres.2015.02.053","volume":"1628","author":"CA Hanlon","year":"2015","unstructured":"Hanlon CA, Dowdle LT, Austelle CW et al (2015) What goes up can come down: novel brain stimulation therapies for treating addiction. Brain Res 1628:199\u2013209","journal-title":"Brain Res"},{"key":"1595_CR64","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1007\/7854_2014_282","volume":"23","author":"S Heckers","year":"2015","unstructured":"Heckers S, Konradi C (2015) Hippocampal pathology in schizophrenia. Curr Top Behav Neurosci 23:529\u2013553. https:\/\/doi.org\/10.1007\/7854_2014_282","journal-title":"Curr Top Behav Neurosci"},{"key":"1595_CR65","first-page":"611","volume":"11","author":"J Herron","year":"2017","unstructured":"Herron J et al (2017) Chronic electrocorticography is used to sense movement intention and closed-loop deep brain stimulation with wearable sensors in PD. Front Neurosci 11:611","journal-title":"Front Neurosci"},{"issue":"1","key":"1595_CR66","first-page":"1","volume":"230","author":"TH Hicks","year":"2025","unstructured":"Hicks TH et al (2025) Functional and structural cerebellar-behavior relationships in aging. Brain Struct Funct 230(1):1\u201324","journal-title":"Brain Struct Funct"},{"issue":"9","key":"1595_CR67","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1038\/s41583-019-0194-8","volume":"20","author":"J Huang","year":"2019","unstructured":"Huang J, Paul A (2019) The diversity of GABAergic neurons and neural communication elements. Nat Rev Neurosci 20(9):563\u2013572. https:\/\/doi.org\/10.1038\/s41583-019-0194-8","journal-title":"Nat Rev Neurosci"},{"issue":"1","key":"1595_CR68","first-page":"60","volume":"36","author":"YZ Huang","year":"2022","unstructured":"Huang YZ et al (2022a) Long-term depression and potentiation induced by rTMS: differential effects on motor recovery and cognitive function. Neurorehabil Neural Repair 36(1):60\u201370","journal-title":"Neurorehabil Neural Repair"},{"issue":"4","key":"1595_CR69","first-page":"347","volume":"36","author":"YZ Huang","year":"2022","unstructured":"Huang YZ et al (2022b) Transcranial magnetic stimulation in neuropsychiatric disorders: mechanisms of action and therapeutic applications. Neuropsychology 36(4):347\u2013363","journal-title":"Neuropsychology"},{"key":"1595_CR70","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1038\/s41386-024-02033-8","volume":"50","author":"E Hubbard","year":"2024","unstructured":"Hubbard E et al (2024) Neural basis of adolescent THC-induced potentiation of opioid responses later in life. Neuropsychopharmacology 50:818\u2013827","journal-title":"Neuropsychopharmacology"},{"issue":"12","key":"1595_CR71","doi-asserted-by":"publisher","first-page":"2894","DOI":"10.1002\/jemt.24662","volume":"87","author":"MN Hussein","year":"2024","unstructured":"Hussein MN (2024) Labeling of the serotonergic neuronal circuits emerging from the raphe nuclei via some retrograde tracers. Microsc Res Tech 87(12):2894\u20132914","journal-title":"Microsc Res Tech"},{"key":"1595_CR72","doi-asserted-by":"publisher","DOI":"10.2174\/0118715273337007241115102118","author":"A Inamdar","year":"2025","unstructured":"Inamdar A, Gurupadayya B, Sharma H (2025) The role of glial cells in autism spectrum disorder: molecular mechanisms and therapeutic approaches. CNS Neurol Disord Drug Targets. https:\/\/doi.org\/10.2174\/0118715273337007241115102118","journal-title":"CNS Neurol Disord Drug Targets"},{"issue":"1","key":"1595_CR73","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3390\/ijms26010147","volume":"26","author":"G Innamorati","year":"2024","unstructured":"Innamorati G et al (2024) Characterization of mesenchymal and neural stem cells response to bipolar microsecond electric pulses stimulation. Int J Mol Sci 26(1):147","journal-title":"Int J Mol Sci"},{"issue":"3","key":"1595_CR75","first-page":"450","volume":"28","author":"KL Jackson","year":"2025","unstructured":"Jackson KL et al (2025b) Optogenetic modulation of the pallidothalamic pathway restores motor function in a PD model. Nat Neurosci 28(3):450\u2013462","journal-title":"Nat Neurosci"},{"key":"1595_CR76","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0555-24.2025","author":"J Jackson","year":"2025","unstructured":"Jackson J et al (2025b) Pallidothalamic circuit-selective manipulation ameliorates motor symptoms in a rat model of Parkinsonian. J Neurosci. https:\/\/doi.org\/10.1523\/JNEUROSCI.0555-24.2025","journal-title":"J Neurosci"},{"issue":"5","key":"1595_CR77","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1038\/s41593-018-0070-z","volume":"21","author":"HIL Jacobs","year":"2018","unstructured":"Jacobs HIL et al (2018) Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals. Nat Neurosci 21(5):424\u2013431","journal-title":"Nat Neurosci"},{"issue":"2","key":"1595_CR78","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s41465-019-00160-5","volume":"4","author":"M Jahanshahi","year":"2020","unstructured":"Jahanshahi M et al (2020) The role of rTMS in cognitive enhancement: timing and task-related effects. J Cognit Enhancement 4(2):155\u2013168","journal-title":"J Cognit Enhancement"},{"issue":"11","key":"1595_CR79","first-page":"2873","volume":"214","author":"TR Jay","year":"2017","unstructured":"Jay TR et al (2017) TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in AD mouse models. J Exp Med 214(11):2873\u20132887","journal-title":"J Exp Med"},{"key":"1595_CR80","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1038\/s41380-024-02651-0","volume":"30","author":"KG Johnston","year":"2024","unstructured":"Johnston KG et al (2024a) Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2 R47H Alzheimer\u2019s risk gene mutation. Mol Psychiatry 30:461\u2013477","journal-title":"Mol Psychiatry"},{"issue":"3","key":"1595_CR81","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/s41593-024-01591-w","volume":"27","author":"ER Johnston","year":"2024","unstructured":"Johnston ER et al (2024b) The TREM2^R47H variant alters BDNF signaling and glial responses in a 5xFAD mouse model of AD. Nat Neurosci 27(3):387\u2013399","journal-title":"Nat Neurosci"},{"issue":"7483","key":"1595_CR82","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1038\/nature12983","volume":"505","author":"A Kepecs","year":"2014","unstructured":"Kepecs A, Fishell G (2014) Interneuron cell types are fit to function. Nature 505(7483):318\u2013326. https:\/\/doi.org\/10.1038\/nature12983","journal-title":"Nature"},{"issue":"7","key":"1595_CR83","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1016\/j.cell.2017.05.018","volume":"169","author":"H Keren-Shaul","year":"2017","unstructured":"Keren-Shaul H et al (2017) A unique microglia type associated with restricting development of AD. Cell 169(7):1276-1290.e17","journal-title":"Cell"},{"key":"1595_CR84","first-page":"724184","volume":"13","author":"DH Kim","year":"2022","unstructured":"Kim DH et al (2022) Optimizing rTMS for motor rehabilitation: the role of individualized stimulation protocols. Front Neurol 13:724184","journal-title":"Front Neurol"},{"issue":"1","key":"1595_CR85","doi-asserted-by":"publisher","first-page":"e16253","DOI":"10.1111\/jnc.16253","volume":"169","author":"Y Kitase","year":"2025","unstructured":"Kitase Y et al (2025) CXCR2 immunomodulatory therapy protects against microstructural white matter injury and gait abnormalities but does not mitigate deficits of cognition in a preclinical model of cerebral palsy\u2019. J Neurochem 169(1):e16253","journal-title":"J Neurochem"},{"key":"1595_CR86","first-page":"98","volume":"39","author":"W Koh","year":"2016","unstructured":"Koh W et al (2016) Role of inhibitory interneurons in cortical circuits. Curr Opin Neurobiol 39:98\u2013106","journal-title":"Curr Opin Neurobiol"},{"issue":"2","key":"1595_CR87","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1002\/1531-8249(20010201)49:2<202::AID-ANA40>3.0.CO;2-3","volume":"49","author":"JH Kordower","year":"2001","unstructured":"Kordower JH, Chu Y, Stebbins GT, DeKosky ST (2001) Loss and atrophy of layer II entorhinal cortex neurons in older adults with mild cognitive impairment. Ann Neurol 49(2):202\u2013213","journal-title":"Ann Neurol"},{"issue":"7306","key":"1595_CR88","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1038\/nature09159","volume":"466","author":"AV Kravitz","year":"2010","unstructured":"Kravitz AV et al (2010) Regulation of parkinsonian motor behaviors by optogenetic control of basal ganglia circuitry. Nature 466(7306):622\u2013626","journal-title":"Nature"},{"issue":"12","key":"1595_CR89","doi-asserted-by":"publisher","first-page":"a009621","DOI":"10.1101\/cshperspect.a009621","volume":"2","author":"JL Lanciego","year":"2012","unstructured":"Lanciego JL, Luquin N, Obeso JA (2012) Functional neuroanatomy of the basal ganglia. Cold Spring Harb Perspect Med 2(12):a009621","journal-title":"Cold Spring Harb Perspect Med"},{"key":"1595_CR90","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1038\/s41593-024-01821-1","volume":"28","author":"K-S Lee","year":"2024","unstructured":"Lee K-S et al (2024a) Emergence of a brainstem somatosensory tonotopic map for substrate vibration. Nat Neurosci 28:97\u2013104","journal-title":"Nat Neurosci"},{"key":"1595_CR91","first-page":"63","volume":"476","author":"S Lee","year":"2024","unstructured":"Lee S et al (2024b) Development of tonotopic and somatotopic maps in the brainstem\u2019s somatosensory system. Neuroscience 476:63\u201374","journal-title":"Neuroscience"},{"key":"1595_CR92","first-page":"651132","volume":"15","author":"G Leinenga","year":"2021","unstructured":"Leinenga G et al (2021) Tactical ultrasound applications for targeted therapy in AD. Front Neurosci 15:651132","journal-title":"Front Neurosci"},{"issue":"3","key":"1595_CR93","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1038\/s41582-020-00435-y","volume":"17","author":"F Leng","year":"2021","unstructured":"Leng F, Edison P (2021) Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here? Nat Rev Neurol 17(3):157\u2013172","journal-title":"Nat Rev Neurol"},{"issue":"4","key":"1595_CR94","first-page":"987","volume":"87","author":"J Li","year":"2023","unstructured":"Li J et al (2023a) The effects of GLP-1 receptor agonists on cognitive decline in AD: a clinical trial perspective. J AD 87(4):987\u20131001","journal-title":"J AD"},{"issue":"3","key":"1595_CR95","first-page":"555","volume":"48","author":"Y Li","year":"2023","unstructured":"Li Y et al (2023b) Sleep disturbances in depression and anxiety disorders: mechanisms and therapeutic strategies. Neuropsychopharmacology 48(3):555\u2013569","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"1595_CR97","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/s43856-025-00736-7","volume":"5","author":"G Li","year":"2025","unstructured":"Li G et al (2025a) Revealing excitation-inhibition imbalance in AD using multiscale neural model inversion of resting-state functional MRI. Commun Med 5(1):17","journal-title":"Commun Med"},{"key":"1595_CR98","first-page":"119072","volume":"254","author":"J Li","year":"2025","unstructured":"Li J et al (2025b) Disruption of excitation-inhibition balance in AD: Insights from resting-state fMRI and multiscale modeling. Neuroimage 254:119072","journal-title":"Neuroimage"},{"key":"1595_CR99","unstructured":"Li X et al (2023b) White matter architecture and brain network efficiency across the adult lifespan"},{"issue":"25","key":"1595_CR100","doi-asserted-by":"publisher","first-page":"10071","DOI":"10.1073\/pnas.1204606109","volume":"109","author":"A Limon","year":"2012","unstructured":"Limon A, Reyes-Ruiz JM, Miledi R (2012) Loss of functional GABA(A) receptors in the Alzheimer diseased brain. Proc Natl Acad Sci 109(25):10071\u201310076","journal-title":"Proc Natl Acad Sci"},{"issue":"12","key":"1595_CR101","doi-asserted-by":"publisher","first-page":"e3001127","DOI":"10.1371\/journal.pbio.3001127","volume":"19","author":"X Lin","year":"2021","unstructured":"Lin X et al (2021) Noncanonical projections to the hippocampal CA3 regulate spatial learning and memory by modulating the feedforward hippocampal trisynaptic pathway. PLoS Biol 19(12):e3001127","journal-title":"PLoS Biol"},{"key":"1595_CR102","first-page":"634089","volume":"16","author":"Z Lin","year":"2022","unstructured":"Lin Z et al (2022a) Impaired spatial memory and neuronal firing in the 3xTg-AD mouse model: a study on hippocampal network dysfunction. Front Neurosci 16:634089","journal-title":"Front Neurosci"},{"key":"1595_CR103","doi-asserted-by":"publisher","first-page":"105562","DOI":"10.1016\/j.nbd.2021.105562","volume":"162","author":"X Lin","year":"2022","unstructured":"Lin X et al (2022b) Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic AD mouse model. Neurobiol Dis 162:105562","journal-title":"Neurobiol Dis"},{"issue":"13","key":"1595_CR104","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1002\/cne.25510","volume":"531","author":"X Lin","year":"2023","unstructured":"Lin X et al (2023) Hippocampal CA3 inhibitory neurons receive extensive noncanonical synaptic inputs from CA1 and subicular complex. J Compar Neurol 531(13):1333\u20131347","journal-title":"J Compar Neurol"},{"issue":"5","key":"1595_CR105","first-page":"324","volume":"12","author":"X Liu","year":"2022","unstructured":"Liu X et al (2022) Neural connectivity and cognitive deficits in ASD: Insights from DTI and fMRI studies. Brain Connect 12(5):324\u2013335","journal-title":"Brain Connect"},{"issue":"2","key":"1595_CR106","first-page":"272","volume":"28","author":"W Liu","year":"2023","unstructured":"Liu W et al (2023) GLP-1 receptor activation and its antidepressant effects: a focus on neuroplasticity and neurogenesis. Mol Psychiatry 28(2):272\u2013285","journal-title":"Mol Psychiatry"},{"key":"1595_CR107","unstructured":"Lom B (2018) A review of developmental neurobiology by Lynne M. Bianchi (in the context of one instructor\u2019s evolving relationship with scientific textbooks). J Undergrad Neurosci Educ 17(1): R1."},{"issue":"14","key":"1595_CR108","first-page":"2827","volume":"529","author":"A L\u00f3pez","year":"2021","unstructured":"L\u00f3pez A et al (2021) Comparative anatomy of the cholinergic system and the vagus nerve in humans and rodents. J Compar Neurol 529(14):2827\u20132839","journal-title":"J Compar Neurol"},{"issue":"5","key":"1595_CR109","first-page":"1150","volume":"13","author":"V L\u00f3pez-Alonso","year":"2020","unstructured":"L\u00f3pez-Alonso V et al (2020) Prefrontal cortex modulation with rTMS in patients with cognitive deficits. Brain Stimul 13(5):1150\u20131159","journal-title":"Brain Stimul"},{"key":"1595_CR110","first-page":"786306","volume":"12","author":"V L\u00f3pez-Alonso","year":"2021","unstructured":"L\u00f3pez-Alonso V et al (2021) Neuromodulation in autism spectrum disorder: a review of therapeutic potential of tDCS and cTBS. Front Psychol 12:786306","journal-title":"Front Psychol"},{"issue":"3","key":"1595_CR111","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.neuron.2013.01.020","volume":"77","author":"AM Lozano","year":"2013","unstructured":"Lozano AM, Lipsman N (2013) Probing and regulating dysfunctional circuits using deep brain stimulation. Neuron 77(3):406\u2013424","journal-title":"Neuron"},{"issue":"3","key":"1595_CR112","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1038\/s41582-018-0128-2","volume":"15","author":"AM Lozano","year":"2019","unstructured":"Lozano AM et al (2019) Deep brain stimulation: current challenges and future directions. Nat Rev Neurol 15(3):148\u2013160","journal-title":"Nat Rev Neurol"},{"key":"1595_CR113","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.pharmthera.2014.11.009","volume":"148","author":"DI Lubman","year":"2015","unstructured":"Lubman DI, Cheetham A, Y\u00fccel M (2015) Cannabis and adolescent brain development. Pharmacol Ther 148:1\u201316. https:\/\/doi.org\/10.1016\/j.pharmthera.2014.11.009","journal-title":"Pharmacol Ther"},{"issue":"2","key":"1595_CR114","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.neuron.2018.03.040","volume":"98","author":"L Luo","year":"2018","unstructured":"Luo L, Callaway EM, Svoboda K (2018) Genetic dissection of neural circuits: a decade of progress. Neuron 98(2):256\u2013281","journal-title":"Neuron"},{"issue":"2","key":"1595_CR115","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.neuron.2018.03.040","volume":"98","author":"L Luo","year":"2020","unstructured":"Luo L, Callaway EM, Svoboda K (2020) Genetic dissection of neural circuits: a decade of progress. Neuron 98(2):256\u2013281","journal-title":"Neuron"},{"key":"1595_CR116","first-page":"1","volume":"17","author":"X Luo","year":"2023","unstructured":"Luo X et al (2023) Optogenetic modulation of prefrontal circuits in social cognition and autism: current perspectives and future directions. Front Neurosci 17:1\u201316","journal-title":"Front Neurosci"},{"issue":"1","key":"1595_CR117","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1038\/s41467-025-56258-2","volume":"16","author":"Z Luo","year":"2025","unstructured":"Luo Z et al (2025a) Treadmill exercise prevents stress-induced anxiety-like behaviors via enhancing the excitatory input from the primary motor cortex to the thalamocortical circuit. Nat Commun 16(1):939","journal-title":"Nat Commun"},{"issue":"1","key":"1595_CR118","first-page":"132","volume":"50","author":"X Luo","year":"2025","unstructured":"Luo X et al (2025b) The neuroprotective effects of treadmill exercise on thalamocortical circuits in rats under chronic stress. Neuropsychopharmacology 50(1):132\u2013142","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"1595_CR119","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1111\/1467-9450.00233","volume":"42","author":"EA Maguire","year":"2001","unstructured":"Maguire EA (2001) The retrosplenial contribution to human navigation: a review of lesion and neuroimaging findings. Scand J Psychol 42(3):225\u2013238. https:\/\/doi.org\/10.1111\/1467-9450.00233","journal-title":"Scand J Psychol"},{"issue":"1","key":"1595_CR120","first-page":"1","volume":"37","author":"P Maldonado","year":"2023","unstructured":"Maldonado P et al (2023) Cerebellar tDCS modulates cerebello-cortical connectivity: temporal dynamics and clinical implications. Neurorehabil Neural Repair 37(1):1\u201314","journal-title":"Neurorehabil Neural Repair"},{"issue":"2","key":"1595_CR121","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s13311-022-01325-5","volume":"20","author":"DJ Manocchio","year":"2023","unstructured":"Manocchio DJ et al (2023) Neuromodulation therapies for PTSD: the impact of tDCS and rTMS on brain circuits. Neurotherapeutics 20(2):431\u2013445","journal-title":"Neurotherapeutics"},{"issue":"1","key":"1595_CR123","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1038\/s41467-017-00180-9","volume":"8","author":"D Mao","year":"2017","unstructured":"Mao D, Kandler S, McNaughton BL, Bonin V (2017) Sparse orthogonal population representation of spatial context in retrosplenial cortex. Nat Commun 8(1):243. https:\/\/doi.org\/10.1038\/s41467-017-00180-9","journal-title":"Nat Commun"},{"issue":"6","key":"1595_CR124","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1093\/schbul\/sbx180","volume":"44","author":"R McCutcheon","year":"2018","unstructured":"McCutcheon R et al (2018) Defining the locus of dopaminergic dysfunction in schizophrenia: a meta-analysis and test of the mesolimbic hypothesis. Schizophr Bull 44(6):1301\u20131311","journal-title":"Schizophr Bull"},{"issue":"4","key":"1595_CR125","first-page":"1268","volume":"52","author":"RC Miall","year":"2021","unstructured":"Miall RC et al (2021) The role of the cerebellum in motor recovery after stroke: insights from cerebellar-cortical networks. Stroke 52(4):1268\u20131277","journal-title":"Stroke"},{"issue":"2\u20133","key":"1595_CR126","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/S0165-0173(99)00040-5","volume":"31","author":"FA Middleton","year":"2000","unstructured":"Middleton FA, Strick PL (2000) Basal ganglia and cerebellar loops: motor and cognitive circuits. Brain Res Rev 31(2\u20133):236\u2013250","journal-title":"Brain Res Rev"},{"key":"1595_CR127","first-page":"116297","volume":"206","author":"R Miller","year":"2020","unstructured":"Miller R et al (2020) Advances in real-time fMRI and EEG for neuromodulation studies. Neuroimage 206:116297","journal-title":"Neuroimage"},{"key":"1595_CR128","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2024.105960","author":"C Morawetz","year":"2024","unstructured":"Morawetz C et al (2024) Emotion regulation: from neural circuits to a transdiagnostic perspective\u2019. Neurosci Biobehav Rev. https:\/\/doi.org\/10.1016\/j.neubiorev.2024.105960","journal-title":"Neurosci Biobehav Rev"},{"key":"1595_CR129","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1146\/annurev.neuro.31.061307.090723","volume":"31","author":"EI Moser","year":"2008","unstructured":"Moser EI, Kropff E, Moser MB (2008) Place cells, grid cells, and the brain\u2019s spatial representation system. Annu Rev Neurosci 31:69\u201389","journal-title":"Annu Rev Neurosci"},{"issue":"5","key":"1595_CR130","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1038\/nrn1385","volume":"5","author":"K Nakazawa","year":"2017","unstructured":"Nakazawa K, McHugh TJ, Wilson MA, Tonegawa S (2017) NMDA receptors, place cells and hippocampal spatial memory. Nat Rev Neurosci 5(5):361\u2013372. https:\/\/doi.org\/10.1038\/nrn1385","journal-title":"Nat Rev Neurosci"},{"key":"1595_CR131","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2024.09.011","author":"MM Nour","year":"2024","unstructured":"Nour MM et al (2024) Cognitive maps and schizophrenia. Trends Cognit Sci. https:\/\/doi.org\/10.1016\/j.tics.2024.09.011","journal-title":"Trends Cognit Sci"},{"key":"1595_CR132","volume-title":"The hippocampus as a cognitive map","author":"J O\u2019Keefe","year":"1978","unstructured":"O\u2019Keefe J, Nadel L (1978) The hippocampus as a cognitive map. Clarendon Press, Oxford"},{"issue":"2","key":"1595_CR133","first-page":"S30","volume":"64","author":"JA Obeso","year":"2014","unstructured":"Obeso JA et al (2014) The basal ganglia in PD: current concepts and unexplained observations. Ann Neurol 64(2):S30\u2013S46","journal-title":"Ann Neurol"},{"issue":"9","key":"1595_CR134","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1002\/mds.27115","volume":"32","author":"JA Obeso","year":"2017","unstructured":"Obeso JA et al (2017) Past, present, and future of PD: an exceptional essay on the 200th Anniversary of the Shaking Palsy. Mov Disord 32(9):1264\u20131310","journal-title":"Mov Disord"},{"issue":"11","key":"1595_CR135","doi-asserted-by":"publisher","first-page":"e25683","DOI":"10.1002\/cne.25683","volume":"532","author":"LM Oliveira","year":"2024","unstructured":"Oliveira LM et al (2024) Afferent and efferent connections of the postinspiratory complex (PiCo) revealed by AAV and monosynaptic rabies viral tracing. J Compar Neurol 532(11):e25683","journal-title":"J Compar Neurol"},{"issue":"4","key":"1595_CR136","first-page":"451","volume":"91","author":"WM Ong","year":"2023","unstructured":"Ong WM, Tang HL (2023) Subthreshold rTMS and context-dependent neuronal plasticity: implications for personalized neuromodulation therapies. J Neurosci Res 91(4):451\u2013460","journal-title":"J Neurosci Res"},{"issue":"2","key":"1595_CR137","doi-asserted-by":"publisher","first-page":"eado6705","DOI":"10.1126\/sciadv.ado6705","volume":"11","author":"RC Ong","year":"2025","unstructured":"Ong RC, Tang AD (2025) Subthreshold repetitive transcranial magnetic stimulation induces cortical layer\u2013, brain region\u2013, and protocol-dependent neural plasticity. Sci Adv 11(2):eado6705","journal-title":"Sci Adv"},{"issue":"1","key":"1595_CR138","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-024-54564-9","volume":"15","author":"T Osada","year":"2024","unstructured":"Osada T et al (2024a) Multiple insular-prefrontal pathways underlie perception to execution during response inhibition in humans. Nat Commun 15(1):1\u201317","journal-title":"Nat Commun"},{"issue":"2","key":"1595_CR139","first-page":"190","volume":"44","author":"T Osada","year":"2024","unstructured":"Osada T et al (2024b) Neural circuits involved in response inhibition: insights from fMRI and TMS. J Neurosci 44(2):190\u2013200","journal-title":"J Neurosci"},{"issue":"1","key":"1595_CR140","doi-asserted-by":"publisher","first-page":"e16636","DOI":"10.1111\/ejn.16636","volume":"61","author":"A Ozkirli","year":"2025","unstructured":"Ozkirli A, Herzog MH, Jastrz\u0119bowska MA (2025a) Computational complexity as a potential limitation on brain\u2013behaviour mapping. Eur J Neurosci 61(1):e16636","journal-title":"Eur J Neurosci"},{"key":"1595_CR141","first-page":"147","volume":"120","author":"F Ozkirli","year":"2025","unstructured":"Ozkirli F, Herzog C, Jastrz\u0119bowska M (2025b) Reevaluating reductionism in neuroscience: a computational approach to brain-behavior mapping. Neurosci Biobehav Rev 120:147\u2013160","journal-title":"Neurosci Biobehav Rev"},{"key":"1595_CR142","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1038\/s41467-017-01150-x","volume":"8","author":"S Palmqvist","year":"2017","unstructured":"Palmqvist S et al (2017) Earliest accumulation of \u03b2-amyloid occurs within the default-mode network and concurrently affects brain connectivity. Nat Commun 8:1214","journal-title":"Nat Commun"},{"key":"1595_CR143","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0969-24.2024","author":"S Parkins","year":"2024","unstructured":"Parkins S et al (2024) Spatial mapping of activity changes across sensory areas following visual deprivation in adults. J Neurosci. https:\/\/doi.org\/10.1523\/JNEUROSCI.0969-24.2024","journal-title":"J Neurosci"},{"issue":"1","key":"1595_CR144","first-page":"33","volume":"82","author":"A Pascual-Leone","year":"2021","unstructured":"Pascual-Leone A et al (2021) rTMS combined with pharmacological treatments: synergistic effects on brain plasticity. J Clin Psychiatry 82(1):33\u201341","journal-title":"J Clin Psychiatry"},{"key":"1595_CR145","first-page":"315","volume":"14","author":"EA Pereira","year":"2020","unstructured":"Pereira EA et al (2020) Vagus nerve stimulation and cholinergic neurotransmission: preclinical evidence from rodent models. Front Neurosci 14:315","journal-title":"Front Neurosci"},{"issue":"6","key":"1595_CR146","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1016\/j.neuron.2014.04.041","volume":"82","author":"M Pisanello","year":"2017","unstructured":"Pisanello M, Sileo L, Oldenburg IA et al (2017) Multipoint-emitting optical fibers for spatially addressable in vivo optogenetics. Neuron 82(6):1245\u20131258","journal-title":"Neuron"},{"issue":"6301","key":"1595_CR147","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1126\/science.aag2590","volume":"353","author":"RM Ransohoff","year":"2016","unstructured":"Ransohoff RM (2016) How neuroinflammation contributes to neurodegeneration. Science 353(6301):777\u2013783","journal-title":"Science"},{"issue":"11","key":"1595_CR148","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1038\/nrn2915","volume":"11","author":"P Redgrave","year":"2010","unstructured":"Redgrave P, Rodriguez M, Smith Y, Rodriguez-Oroz MC, Lehericy S, Bergman H et al (2010) Goal-directed and habitual control in the basal ganglia: implications for Parkinson\u2019s disease. Nat Rev Neurosci 11(11):760\u2013772","journal-title":"Nat Rev Neurosci"},{"issue":"2","key":"1595_CR149","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/j.cell.2018.07.043","volume":"175","author":"J Ren","year":"2018","unstructured":"Ren J, Friedmann D, Xiong J et al (2018) Anatomically defined and functionally distinct dorsal raphe serotonin sub-systems. Cell 175(2):472-487.e20","journal-title":"Cell"},{"key":"1595_CR150","first-page":"728614","volume":"17","author":"Y Ren","year":"2023","unstructured":"Ren Y et al (2023) Lavender essential oil promotes sleep in C57BL\/6J mice through modulation of GABAergic neurons and the olfactory system. Front Neurosci 17:728614","journal-title":"Front Neurosci"},{"issue":"6","key":"1595_CR151","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1177\/0706743717707812","volume":"62","author":"J Renard","year":"2017","unstructured":"Renard J, Rushlow WJ, Laviolette SR (2017) What can rats tell us about adolescent cannabis exposure? Insights from preclinical research. Can J Psychiat 62(6):399\u2013408. https:\/\/doi.org\/10.1177\/0706743717707812","journal-title":"Can J Psychiat"},{"issue":"7931","key":"1595_CR152","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1038\/s41586-022-05277-w","volume":"610","author":"O Revah","year":"2022","unstructured":"Revah O et al (2022) \u201cMaturation and circuit integration of transplanted human cortical organoids. Nature 610(7931):319\u2013326","journal-title":"Nature"},{"issue":"5","key":"1595_CR153","first-page":"849","volume":"13","author":"JO Rinne","year":"1998","unstructured":"Rinne JO, Svedberg T, L\u00f6nnberg P, N\u00e5gren K (1998) Dopamine transporter in Parkinson\u2019s disease: a longitudinal study with [123I]\u03b2-CIT SPECT. Mov Disord 13(5):849\u2013854","journal-title":"Mov Disord"},{"issue":"4","key":"1595_CR154","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1016\/j.neuron.2016.01.040","volume":"89","author":"BL Roth","year":"2016","unstructured":"Roth BL (2016) DREADDs for neuroscientists. Neuron 89(4):683\u2013694","journal-title":"Neuron"},{"issue":"7","key":"1595_CR155","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.biopsych.2015.07.024","volume":"79","author":"T Rubino","year":"2016","unstructured":"Rubino T, Parolaro D (2016) The impact of exposure to cannabinoids in adolescence: insights from animal models. Biol Psychiat 79(7):578\u2013585. https:\/\/doi.org\/10.1016\/j.biopsych.2015.07.024","journal-title":"Biol Psychiat"},{"issue":"3","key":"1595_CR156","first-page":"295","volume":"95","author":"M Sadeh","year":"2024","unstructured":"Sadeh M et al (2024) Circuit-specific neuromodulation for improving cognitive flexibility and treating mood disorders. Biol Psychiat 95(3):295\u2013305","journal-title":"Biol Psychiat"},{"issue":"9","key":"1595_CR157","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1038\/nm.4397","volume":"23","author":"MW Salter","year":"2017","unstructured":"Salter MW, Stevens B (2017) Microglia emerge as central players in brain disease. Nat Med 23(9):1018\u20131027","journal-title":"Nat Med"},{"issue":"1","key":"1595_CR158","first-page":"1","volume":"79","author":"ME Sanchez","year":"2024","unstructured":"Sanchez ME et al (2024) Loss of oscillatory activity in AD models: implications for memory and cognition. Journal of AD 79(1):1\u201318","journal-title":"Journal of AD"},{"key":"1595_CR159","first-page":"26","volume":"171","author":"JD Schmahmann","year":"2021","unstructured":"Schmahmann JD (2021) The cerebellum and cognition: a review of the literature. Brain Res Bull 171:26\u201332","journal-title":"Brain Res Bull"},{"key":"1595_CR350","doi-asserted-by":"crossref","unstructured":"Schwarzkopf DS, Zhang J, Kourtzi Z (2009) Flexible learning of natural statistics in the human brain. J Neurophysiol 102(3):1854\u20131867","DOI":"10.1152\/jn.00028.2009"},{"issue":"6","key":"1595_CR160","doi-asserted-by":"publisher","first-page":"595","DOI":"10.15252\/emmm.201606210","volume":"8","author":"DJ Selkoe","year":"2016","unstructured":"Selkoe DJ, Hardy J (2016) The amyloid hypothesis of Alzheimer\u2019s disease at 25 years. EMBO Mol Med 8(6):595\u2013608. https:\/\/doi.org\/10.15252\/emmm.201606210","journal-title":"EMBO Mol Med"},{"issue":"5","key":"1595_CR161","first-page":"1003","volume":"108","author":"B Shah","year":"2023","unstructured":"Shah B et al (2023) In vivo calcium imaging reveals the impact of amyloid plaques and tau on hippocampal network activity. Neuron 108(5):1003\u20131015","journal-title":"Neuron"},{"issue":"1","key":"1595_CR162","doi-asserted-by":"publisher","first-page":"e23662","DOI":"10.1002\/hipo.23662","volume":"35","author":"PE Sharp","year":"2025","unstructured":"Sharp PE (2025) From british associationism to the hippocampal cognitive map: a personal view from a ringside seat at the cognitive\/PDP revolution. Hippocampus 35(1):e23662","journal-title":"Hippocampus"},{"issue":"4","key":"1595_CR163","first-page":"745","volume":"50","author":"Y Shi","year":"2025","unstructured":"Shi Y et al (2025a) The role of cortical interneurons in addiction: implications for therapy. Neuropsychopharmacology 50(4):745\u2013758","journal-title":"Neuropsychopharmacology"},{"key":"1595_CR164","doi-asserted-by":"publisher","DOI":"10.1177\/10738584241310156","author":"S Shi","year":"2025","unstructured":"Shi S et al (2025b) Exploring cortical interneurons in substance use disorder: from mechanisms to therapeutic perspectives. Neuroscientist. https:\/\/doi.org\/10.1177\/10738584241310156","journal-title":"Neuroscientist"},{"key":"1595_CR165","first-page":"1","volume":"295","author":"LM Shin","year":"2022","unstructured":"Shin LM et al (2022) Resting-state functional connectivity in PTSD: insights from neuroimaging studies. J Affect Disord 295:1\u201310","journal-title":"J Affect Disord"},{"issue":"18","key":"1595_CR300","doi-asserted-by":"publisher","first-page":"2667","DOI":"10.3390\/polym16182667","volume":"16","author":"JC Silva","year":"2024","unstructured":"Silva JC, Ferreira FC (2024) Advanced polymeric scaffolds for stem cell engineering and regenerative medicine. Polymers 16(18):2667","journal-title":"Polymers"},{"issue":"9","key":"1595_CR166","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1038\/s41380-019-0426-0","volume":"24","author":"VS Sohal","year":"2019","unstructured":"Sohal VS, Rubenstein JL (2019) Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders. Mol Psychiatry 24(9):1248\u20131257. https:\/\/doi.org\/10.1038\/s41380-019-0426-0","journal-title":"Mol Psychiatry"},{"issue":"1","key":"1595_CR167","doi-asserted-by":"publisher","first-page":"e70011","DOI":"10.1111\/adb.70011","volume":"30","author":"G Soleimani","year":"2025","unstructured":"Soleimani G et al (2025) Targeting VMPFC-amygdala circuit with TMS in substance use disorder: a mechanistic framework. Addict Biol 30(1):e70011","journal-title":"Addict Biol"},{"issue":"4","key":"1595_CR168","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/s11065-010-9148-4","volume":"20","author":"J Stiles","year":"2010","unstructured":"Stiles J, Jernigan TL (2010) The basics of brain development. Neuropsychol Rev 20(4):327\u2013348","journal-title":"Neuropsychol Rev"},{"key":"1595_CR169","doi-asserted-by":"publisher","first-page":"e03197","DOI":"10.7554\/eLife.03197","volume":"3","author":"Y Sun","year":"2014","unstructured":"Sun Y, Grieco SF, Holmes TC, Xu X (2014) Local and long-range circuit connections to hilar mossy cells in the dentate gyrus. Elife 3:e03197. https:\/\/doi.org\/10.7554\/eLife.03197","journal-title":"Elife"},{"issue":"11","key":"1595_CR170","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1038\/s41593-019-0496-y","volume":"22","author":"Y Sun","year":"2019","unstructured":"Sun Y et al (2019) CA1-projecting subiculum neurons facilitate object\u2013place learning. Nat Neurosci 22(11):1857\u20131870","journal-title":"Nat Neurosci"},{"issue":"2","key":"1595_CR171","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.neuron.2022.11.008","volume":"111","author":"W Sun","year":"2023","unstructured":"Sun W, Poschmann J, Cruz-Herrera del Rosario R, Parikshak N, Hajan HS, Geschwind DH (2023) Epigenomic regulation of brain aging and neurodegeneration. Neuron 111(2):215-235.e7. https:\/\/doi.org\/10.1016\/j.neuron.2022.11.008","journal-title":"Neuron"},{"key":"1595_CR172","first-page":"86","volume":"101","author":"DG Sweeney","year":"2023","unstructured":"Sweeney DG et al (2023) GLP-1 receptor agonists in AD: preclinical and clinical evidence for cognitive and neuroprotective effects. Neurobiol Aging 101:86\u201397","journal-title":"Neurobiol Aging"},{"issue":"3","key":"1595_CR173","first-page":"1009","volume":"15","author":"K Tabei","year":"2022","unstructured":"Tabei K et al (2022) Diffusion tensor imaging in neuromodulation: mapping structural connectivity changes with tDCS. Brain Stimul 15(3):1009\u20131020","journal-title":"Brain Stimul"},{"key":"1595_CR174","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.neuroscience.2024.10.046","volume":"562","author":"BA Taha","year":"2024","unstructured":"Taha BA et al (2024) Nanostructured photonics probes: a transformative approach in neurotherapeutics and brain circuitry. Neuroscience 562:106\u2013124","journal-title":"Neuroscience"},{"key":"1595_CR175","first-page":"147","volume":"1785","author":"LS Tavakkol","year":"2022","unstructured":"Tavakkol LS et al (2022) Genetic and epigenetic factors influencing individual responses to rTMS in neurological disorders. Brain Res 1785:147\u2013159","journal-title":"Brain Res"},{"issue":"3","key":"1595_CR176","first-page":"470","volume":"15","author":"A Thielscher","year":"2022","unstructured":"Thielscher A et al (2022) Computational modeling of non-invasive brain stimulation: new frontiers for personalized therapy. Brain Stimul 15(3):470\u2013482","journal-title":"Brain Stimul"},{"issue":"14","key":"1595_CR177","first-page":"1227","volume":"33","author":"A Treble","year":"2016","unstructured":"Treble A, Hasan KM, Iftikhar A, Stuebing KK, Kramer LA, Cox CS Jr, Ewing-Cobbs L (2016) Working memory and corpus callosum microstructural integrity after pediatric traumatic brain injury: a diffusion tensor tractography study. J Neurotrauma 33(14):1227\u20131234","journal-title":"J Neurotrauma"},{"issue":"2","key":"1595_CR178","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.neuron.2016.06.033","volume":"91","author":"R Tremblay","year":"2016","unstructured":"Tremblay R, Lee S, Rudy B (2016) GABAergic interneurons in the neocortex: from cellular properties to circuits. Neuron 91(2):260\u2013292. https:\/\/doi.org\/10.1016\/j.neuron.2016.06.033","journal-title":"Neuron"},{"key":"1595_CR179","doi-asserted-by":"publisher","first-page":"1523614","DOI":"10.3389\/fncir.2024.1523614","volume":"18","author":"M Uchigashima","year":"2024","unstructured":"Uchigashima M, Mikuni T (2024) Single cell synaptome mapping: its technical basis and applications in critical period plasticity research. Front Neural Circ 18:1523614","journal-title":"Front Neural Circ"},{"issue":"11","key":"1595_CR180","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1038\/s41582-018-0072-1","volume":"14","author":"TK Ulland","year":"2018","unstructured":"Ulland TK, Colonna M (2018) TREM2\u2014a key player in microglial biology and Alzheimer disease. Nat Rev Neurol 14(11):667\u2013675","journal-title":"Nat Rev Neurol"},{"issue":"2","key":"1595_CR181","first-page":"356","volume":"147","author":"CR Vanderlip","year":"2024","unstructured":"Vanderlip CR et al (2024a) Basal frontotemporal amyloid accumulation disrupts temporal event memory in preclinical AD. Brain 147(2):356\u2013369","journal-title":"Brain"},{"key":"1595_CR182","doi-asserted-by":"publisher","DOI":"10.1101\/2024.08.23.609449","author":"CR Vanderlip","year":"2024","unstructured":"Vanderlip CR et al (2024b) Amyloid-\u03b2 deposition in basal frontotemporal cortex is associated with selective disruption of temporal mnemonic discrimination. bioRxiv. https:\/\/doi.org\/10.1101\/2024.08.23.609449","journal-title":"bioRxiv"},{"issue":"11","key":"1595_CR183","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1038\/nrn2733","volume":"10","author":"SD Vann","year":"2009","unstructured":"Vann SD, Aggleton JP, Maguire EA (2009) What does the retrosplenial cortex do? Nat Rev Neurosci 10(11):792\u2013802. https:\/\/doi.org\/10.1038\/nrn2733","journal-title":"Nat Rev Neurosci"},{"issue":"23","key":"1595_CR184","doi-asserted-by":"publisher","first-page":"2219","DOI":"10.1056\/NEJMra1402309","volume":"370","author":"ND Volkow","year":"2016","unstructured":"Volkow ND, Baler RD, Compton WM, Weiss SR (2016) Adverse health effects of marijuana use. N Engl J Med 370(23):2219\u20132227. https:\/\/doi.org\/10.1056\/NEJMra1402309","journal-title":"N Engl J Med"},{"key":"1595_CR185","unstructured":"Vounatsos K, Gittis A (2025a) Circuit-specific modulation of basal ganglia output to retrorubral field integrates dopaminergic and GABAergic signaling in cognitive-motor regulation. J Neurosci, In Press"},{"key":"1595_CR186","doi-asserted-by":"crossref","unstructured":"Vounatsos MV, Gittis AH (2025b) GPe Projections to the retrorubral field give rise to diverging GABAergic and DAergic circuits. J Neurosci 45(2):e1446242024","DOI":"10.1523\/JNEUROSCI.1446-24.2024"},{"key":"1595_CR187","unstructured":"Wang J et al (2024a) Microstructural disruption of cortico-striato-thalamo-cortical circuits in PD: implications for motor and cognitive dysfunction. Brain Commun. 6(1):fcad312"},{"key":"1595_CR188","doi-asserted-by":"publisher","first-page":"111116","DOI":"10.1016\/j.pnpbp.2024.111116","volume":"135","author":"L Wang","year":"2024","unstructured":"Wang L et al (2024b) Characterizing microstructural patterns within the cortico-striato-thalamo-cortical circuit in PD. Prog Neuropsychopharmacol Biol Psychiatry 135:111116","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"6","key":"1595_CR189","first-page":"1012","volume":"106","author":"MA Warden","year":"2024","unstructured":"Warden MA et al (2024) Optogenetics for studying inhibitory control in neural circuits. Neuron 106(6):1012\u20131025","journal-title":"Neuron"},{"issue":"4","key":"1595_CR190","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.7150\/thno.103033","volume":"15","author":"R Wen","year":"2025","unstructured":"Wen R et al (2025) Revisiting the unobtrusive role of exogenous stem cells beyond neural circuits replacement in spinal cord injury repair\u2019. Theranostics 15(4):1552","journal-title":"Theranostics"},{"key":"1595_CR191","first-page":"42","volume":"89","author":"RS Wilson","year":"2022","unstructured":"Wilson RS et al (2022) Sleep disturbances and neurodegenerative disease: mechanisms, evidence, and therapeutic approaches. Brain Res Rev 89:42\u201355","journal-title":"Brain Res Rev"},{"issue":"6011","key":"1595_CR192","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1126\/science.1193771","volume":"330","author":"IB Witten","year":"2010","unstructured":"Witten IB, Lin SC, Brodsky M, Prakash R, Diester I, Anikeeva P et al (2010) Cholinergic interneurons control local circuit activity and cocaine conditioning. Science 330(6011):1677\u20131681","journal-title":"Science"},{"issue":"3","key":"1595_CR193","first-page":"458","volume":"16","author":"J Xiao","year":"2023","unstructured":"Xiao J et al (2023) Customized continuous theta burst stimulation improves social communication in children with ASD: a randomized controlled trial. Autism Res 16(3):458\u2013470","journal-title":"Autism Res"},{"issue":"6","key":"1595_CR194","first-page":"zsab144","volume":"46","author":"L Xie","year":"2023","unstructured":"Xie L et al (2023) Optogenetic manipulation of sleep circuits in the central amygdala. Sleep 46(6):zsab144","journal-title":"Sleep"},{"key":"1595_CR195","doi-asserted-by":"publisher","DOI":"10.1101\/2023.12.18.572244","author":"F Xie","year":"2024","unstructured":"Xie F et al (2024) Spatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex. bioRxiv. https:\/\/doi.org\/10.1101\/2023.12.18.572244","journal-title":"bioRxiv"},{"key":"1595_CR196","doi-asserted-by":"publisher","first-page":"110268","DOI":"10.1016\/j.neuropharm.2024.110268","volume":"265","author":"Z Yang","year":"2024","unstructured":"Yang Z et al (2024) Neural circuits and therapeutic mechanisms of empathic pain. Neuropharmacology 265:110268","journal-title":"Neuropharmacology"},{"key":"1595_CR197","doi-asserted-by":"crossref","first-page":"117488","DOI":"10.1016\/j.neuroimage.2020.117488","volume":"225","author":"HT Yap","year":"2021","unstructured":"Yap HT et al (2021) Cortical layer-specific modulation by rTMS: Implications for neuroplasticity in psychiatric and neurological disorders. Neuroimage 225:117488","journal-title":"Neuroimage"},{"key":"1595_CR198","doi-asserted-by":"publisher","first-page":"102225","DOI":"10.1016\/j.gde.2024.102225","volume":"89","author":"Q Yuan","year":"2024","unstructured":"Yuan Q, Zhang S-C (2024) Circuit integration by transplanted human neurons. Curr Opin Genet Dev 89:102225","journal-title":"Curr Opin Genet Dev"},{"key":"1595_CR199","doi-asserted-by":"publisher","DOI":"10.1101\/2024.10.14.618338","author":"N Zemke","year":"2024","unstructured":"Zemke N et al (2024a) Epigenetic and 3D genome reprogramming during the aging of human hippocampus. bioRxiv. https:\/\/doi.org\/10.1101\/2024.10.14.618338","journal-title":"bioRxiv"},{"key":"1595_CR200","unstructured":"Zemke AC et al (2024b) Age-related remodeling of the 3D genome and cellular composition in the human hippocampus"},{"issue":"1","key":"1595_CR201","first-page":"23","volume":"84","author":"Y Zhang","year":"2023","unstructured":"Zhang Y et al (2023a) GLP-1 receptor agonists as a therapeutic approach for substance use disorders: a review of neurobiological effects and clinical findings. J Clin Psychiatry 84(1):23\u201335","journal-title":"J Clin Psychiatry"},{"issue":"2","key":"1595_CR202","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.tins.2022.11.004","volume":"46","author":"X Zhang","year":"2023","unstructured":"Zhang X et al (2023b) Advances in spatial transcriptomics: Unraveling cell\u2013cell interactions in AD. Trends Neurosci 46(2):150\u2013165","journal-title":"Trends Neurosci"},{"key":"1595_CR203","doi-asserted-by":"publisher","first-page":"105939","DOI":"10.1016\/j.nbd.2022.105939","volume":"176","author":"H Zhang","year":"2023","unstructured":"Zhang H et al (2023c) Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for AD. Neurobiol Dis 176:105939","journal-title":"Neurobiol Dis"},{"issue":"1","key":"1595_CR204","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11064-024-04309-3","volume":"50","author":"L Zhang","year":"2025","unstructured":"Zhang L et al (2025) Role of neural circuits in cognitive impairment. Neurochem Res 50(1):1\u201326","journal-title":"Neurochem Res"},{"issue":"4","key":"1595_CR205","first-page":"700","volume":"33","author":"X Zhao","year":"2008","unstructured":"Zhao X et al (2008) Adult neurogenesis in the hippocampus: Implications for brain repair. Neurochem Res 33(4):700\u2013711","journal-title":"Neurochem Res"},{"issue":"5","key":"1595_CR206","first-page":"921","volume":"42","author":"S Zhao","year":"2022","unstructured":"Zhao S et al (2022) Central amygdala circuits in the regulation of sleep and emotional responses. J Neurosci 42(5):921\u2013937","journal-title":"J Neurosci"},{"issue":"688","key":"1595_CR207","first-page":"eabm9714","volume":"15","author":"Y Zhao","year":"2023","unstructured":"Zhao Y et al (2023) Antisense oligonucleotide targeting of TREM2 modulates microglial function and mitigates Alzheimer\u2019s pathology. Sci Transl Med 15(688):eabm9714","journal-title":"Sci Transl Med"},{"issue":"1","key":"1595_CR208","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1038\/s41467-021-21097-4","volume":"12","author":"X Zheng","year":"2021","unstructured":"Zheng X et al (2021) Ht interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex\u2019. Nat Commun 12(1):862","journal-title":"Nat Commun"}],"container-title":["Cellular and Molecular Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10571-025-01595-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10571-025-01595-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10571-025-01595-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T11:02:27Z","timestamp":1765537347000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10571-025-01595-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,26]]},"references-count":206,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1595"],"URL":"https:\/\/doi.org\/10.1007\/s10571-025-01595-5","relation":{},"ISSN":["1573-6830"],"issn-type":[{"value":"1573-6830","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,26]]},"assertion":[{"value":"27 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not Applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}],"article-number":"75"}}