{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T02:33:53Z","timestamp":1787711633173,"version":"build-2784847793"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100025294","name":"Research Ireland","doi-asserted-by":"crossref","award":["20\/FFP-A\/8519"],"award-info":[{"award-number":["20\/FFP-A\/8519"]}],"id":[{"id":"10.13039\/501100025294","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National University of Ireland Postdoctoral Fellowship"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chromosome Res"],"DOI":"10.1007\/s10577-025-09781-3","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T21:33:25Z","timestamp":1758058405000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["CENP-A is diluted during bovine spermatogenesis and is maintained at internally positioned centromere clusters in mature bull sperm"],"prefix":"10.1007","volume":"33","author":[{"given":"Miriama","family":"\u0160tiavnick\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"N\u00ed Nuall\u00e1in","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitr\u00edona M.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine M.","family":"Dunleavy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,9,16]]},"reference":[{"key":"9781_CR1","unstructured":"Agostinelli C, Lund U (2024) circular: Circular Statistics"},{"key":"9781_CR2","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1016\/J.CELL.2019.07.001","volume":"178","author":"T Akera","year":"2019","unstructured":"Akera T, Trimm E, Lampson MA (2019) Molecular strategies of meiotic cheating by selfish centromeres. Cell 178:1132-1144.e10. https:\/\/doi.org\/10.1016\/J.CELL.2019.07.001","journal-title":"Cell"},{"key":"9781_CR3","doi-asserted-by":"publisher","unstructured":"Altemose N, Logsdon GA, Bzikadze A V et al (2022) Complete genomic and epigenetic maps of human centromeres. Science (1979) 376. https:\/\/doi.org\/10.1126\/SCIENCE.ABL4178\/SUPPL_FILE\/SCIENCE.ABL4178_DATABASES_S1_TO_S21.ZIP","DOI":"10.1126\/SCIENCE.ABL4178\/SUPPL_FILE\/SCIENCE.ABL4178_DATABASES_S1_TO_S21.ZIP"},{"key":"9781_CR4","doi-asserted-by":"crossref","unstructured":"Auguie B (2010) gridExtra: Miscellaneous Functions for \u201cGrid\u201d Graphics. CRAN: Contributed Packages","DOI":"10.32614\/CRAN.package.gridExtra"},{"key":"9781_CR5","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/J.NEPIG.2016.08.002","volume":"7","author":"J Behnan","year":"2016","unstructured":"Behnan J, Grieg Z, Joel M et al (2016) Gene knockdown of CENPA reduces sphere forming ability and stemness of glioblastoma initiating cells. Neuroepigenetics 7:6\u201318. https:\/\/doi.org\/10.1016\/J.NEPIG.2016.08.002","journal-title":"Neuroepigenetics"},{"key":"9781_CR6","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1093\/BIOLRE\/IOY021","volume":"99","author":"E Bolcun-Filas","year":"2018","unstructured":"Bolcun-Filas E, Handel MA (2018) Meiosis: the chromosomal foundation of reproduction. Biol Reprod 99:112\u2013126. https:\/\/doi.org\/10.1093\/BIOLRE\/IOY021","journal-title":"Biol Reprod"},{"key":"9781_CR7","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1111\/j.1365-2818.2006.01706.x","volume":"224","author":"S Bolte","year":"2006","unstructured":"Bolte S, Cordeli\u00e8res FP (2006) A guided tour into subcellular colocalization analysis in light microscopy. J Microsc 224:213\u2013232","journal-title":"J Microsc"},{"key":"9781_CR8","doi-asserted-by":"publisher","first-page":"dev198341","DOI":"10.1242\/DEV.198341\/VIDEO-4","volume":"149","author":"KE Brooks","year":"2022","unstructured":"Brooks KE, Daughtry BL, Davis B et al (2022) Molecular contribution to embryonic aneuploidy and karyotypic complexity in initial cleavage divisions of mammalian development. Development (Cambridge) 149:dev198341. https:\/\/doi.org\/10.1242\/DEV.198341\/VIDEO-4","journal-title":"Development (Cambridge)"},{"key":"9781_CR9","doi-asserted-by":"publisher","first-page":"113","DOI":"10.3934\/genet.2018.2.113","volume":"05","author":"V Chagin","year":"2018","unstructured":"Chagin V, Zalensky A, Nazarov I, Mudrak O (2018) Preferable location of chromosomes 1, 29, and X in bovine spermatozoa. AIMS Genet 05:113\u2013123. https:\/\/doi.org\/10.3934\/genet.2018.2.113","journal-title":"AIMS Genet"},{"key":"9781_CR10","doi-asserted-by":"publisher","DOI":"10.3390\/genes9100501","volume":"9","author":"A Champroux","year":"2018","unstructured":"Champroux A, Damon-Soubeyrand C, Goubely C et al (2018) Nuclear integrity but not topology of mouse sperm chromosome is affected by oxidative DNA damage. Genes 9:100501. https:\/\/doi.org\/10.3390\/genes9100501","journal-title":"Genes"},{"key":"9781_CR11","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1038\/s41556-022-00897-w","volume":"24","author":"A Das","year":"2022","unstructured":"Das A, Iwata-Otsubo A, Destouni A et al (2022) Epigenetic, genetic and maternal effects enable stable centromere inheritance. Nat Cell Biol 24:748\u2013756. https:\/\/doi.org\/10.1038\/s41556-022-00897-w","journal-title":"Nat Cell Biol"},{"key":"9781_CR12","doi-asserted-by":"publisher","unstructured":"Dattoli AA, Carty BL, Kochendoerfer AM et al (2020) Asymmetric assembly of centromeres epigenetically regulates stem cell fate. J Cell Biol 219. https:\/\/doi.org\/10.1083\/JCB.201910084\/133868","DOI":"10.1083\/JCB.201910084\/133868"},{"key":"9781_CR13","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1530\/REP-12-0399","volume":"146","author":"RV De Oliveira","year":"2013","unstructured":"De Oliveira RV, Dogan S, Belser LE et al (2013) Molecular morphology and function of bull spermatozoa linked to histones and associated with fertility. Reproduction 146:263\u2013272. https:\/\/doi.org\/10.1530\/REP-12-0399","journal-title":"Reproduction"},{"key":"9781_CR14","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/BF00285884\/METRICS","volume":"96","author":"J del Mazo","year":"1987","unstructured":"del Mazo J, Kremer L, Avila J (1987) Centromeric proteins recognized by CREST sera and meiotic chromosome segregation. Chromosoma 96:55\u201359. https:\/\/doi.org\/10.1007\/BF00285884\/METRICS","journal-title":"Chromosoma"},{"key":"9781_CR15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001460","author":"EM Dunleavy","year":"2012","unstructured":"Dunleavy EM, Beier NL, Gorgescu W et al (2012) The cell cycle timing of centromeric chromatin assembly in Drosophila meiosis is distinct from mitosis yet requires CAL1 and CENP-C. PLoS Biol. https:\/\/doi.org\/10.1371\/journal.pbio.1001460","journal-title":"PLoS Biol"},{"key":"9781_CR16","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1093\/GBE\/EVZ061","volume":"11","author":"A Escudeiro","year":"2019","unstructured":"Escudeiro A, Adega F, Robinson TJ et al (2019) Conservation, divergence, and functions of centromeric satellite DNA families in the Bovidae. Genome Biol Evol 11:1152\u20131165. https:\/\/doi.org\/10.1093\/GBE\/EVZ061","journal-title":"Genome Biol Evol"},{"key":"9781_CR17","doi-asserted-by":"publisher","first-page":"3195","DOI":"10.1016\/J.CELREP.2020.01.097","volume":"30","author":"B Evano","year":"2020","unstructured":"Evano B, Khalilian S, Le Carrou G et al (2020) Dynamics of asymmetric and symmetric divisions of muscle stem cells in vivo and on artificial niches. Cell Rep 30:3195-3206.e7. https:\/\/doi.org\/10.1016\/J.CELREP.2020.01.097","journal-title":"Cell Rep"},{"issue":"5","key":"9781_CR18","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1038\/ncb1397","volume":"8","author":"DR Foltz","year":"2006","unstructured":"Foltz DR, Jansen LET, Black BE et al (2006) The human CENP-A centromeric nucleosome-associated complex. Nature Cell Biol 8(5):458\u2013469. https:\/\/doi.org\/10.1038\/ncb1397","journal-title":"Nature Cell Biol"},{"key":"9781_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/J.GDE.2023.102034","volume":"79","author":"L Gaspa-Toneu","year":"2023","unstructured":"Gaspa-Toneu L, Peters AH (2023) Nucleosomes in mammalian sperm: conveying paternal epigenetic inheritance or subject to reprogramming between generations? Curr Opin Genet Dev 79:102034. https:\/\/doi.org\/10.1016\/J.GDE.2023.102034","journal-title":"Curr Opin Genet Dev"},{"key":"9781_CR20","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1002\/CYTO.A.22463","volume":"85","author":"V Gaysinskaya","year":"2014","unstructured":"Gaysinskaya V, Soh IY, van der Heijden GW, Bortvin A (2014) Optimized flow cytometry isolation of murine spermatocytes. Cytometry A 85:556\u2013565. https:\/\/doi.org\/10.1002\/CYTO.A.22463","journal-title":"Cytometry A"},{"key":"9781_CR21","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/S12958-019-0510-Y","volume":"17","author":"NH Gu","year":"2019","unstructured":"Gu NH, Zhao WL, Wang GS, Sun F (2019) Comparative analysis of mammalian sperm ultrastructure reveals relationships between sperm morphology, mitochondrial functions and motility. Reprod Biol Endocrinol 17:66. https:\/\/doi.org\/10.1186\/S12958-019-0510-Y","journal-title":"Reprod Biol Endocrinol"},{"key":"9781_CR22","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1002\/(SICI)1098-2795(200003)55:3<307::AID-MRD9>3.0.CO;2-P","volume":"55","author":"M Hazzouri","year":"2000","unstructured":"Hazzouri M, Rousseaux S, Mongelard F et al (2000) Genome organization in the human sperm nucleus studied by FISH and confocal microscopy. Mol Reprod Dev 55:307\u2013315. https:\/\/doi.org\/10.1002\/(SICI)1098-2795(200003)55:3%3c307::AID-MRD9%3e3.0.CO;2-P","journal-title":"Mol Reprod Dev"},{"key":"9781_CR23","doi-asserted-by":"publisher","DOI":"10.1038\/srep41585","author":"D Ioannou","year":"2017","unstructured":"Ioannou D, Millan NM, Jordan E, Tempest HG (2017) A new model of sperm nuclear architecture following assessment of the organization of centromeres and telomeres in three-dimensions. Sci Rep. https:\/\/doi.org\/10.1038\/srep41585","journal-title":"Sci Rep"},{"key":"9781_CR24","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1083\/JCB.200701066\/VIDEO-1","volume":"176","author":"LET Jansen","year":"2007","unstructured":"Jansen LET, Black BE, Foltz DR, Cleveland DW (2007) Propagation of centromeric chromatin requires exit from mitosis. J Cell Biol 176:795\u2013805. https:\/\/doi.org\/10.1083\/JCB.200701066\/VIDEO-1","journal-title":"J Cell Biol"},{"key":"9781_CR25","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/S0378-4320(00)00108-1","volume":"60","author":"L Johnson","year":"2000","unstructured":"Johnson L, Varner DD, Roberts ME et al (2000) Efficiency of spermatogenesis: a comparative approach. Anim Reprod Sci 60:471\u2013480. https:\/\/doi.org\/10.1016\/S0378-4320(00)00108-1","journal-title":"Anim Reprod Sci"},{"issue":"8","key":"9781_CR26","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.1038\/s41588-024-01835-2","volume":"56","author":"TS Kalbfleisch","year":"2024","unstructured":"Kalbfleisch TS, McKay SD, Murdoch BM et al (2024) The ruminant telomere-to-telomere (RT2T) consortium. Nature Genetics 56(8):1566\u20131573. https:\/\/doi.org\/10.1038\/s41588-024-01835-2","journal-title":"Nature Genetics"},{"key":"9781_CR27","doi-asserted-by":"publisher","unstructured":"Kixmoeller K, Allu PK, Black BE (2020) The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle. Open Biol 10. https:\/\/doi.org\/10.1098\/RSOB.200051\/","DOI":"10.1098\/RSOB.200051"},{"key":"9781_CR28","doi-asserted-by":"publisher","unstructured":"Kochendoerfer AM, Keegan RS, Dunleavy EM (2023) Centromere proteins are asymmetrically distributed between newly divided germline stem and daughter cells and maintain a balanced niche in Drosophila males. Mol Biol Cell 34. https:\/\/doi.org\/10.1091\/MBC.E22-10-0466\/ASSET\/IMAGES\/LARGE\/MBC-34-AR42-G007.JPEG","DOI":"10.1091\/MBC.E22-10-0466\/ASSET\/IMAGES\/LARGE\/MBC-34-AR42-G007.JPEG"},{"key":"9781_CR29","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1101\/SQB.2017.82.034298","volume":"82","author":"MA Lampson","year":"2017","unstructured":"Lampson MA, Black BE (2017) Cellular and molecular mechanisms of centromere drive. Cold Spring Harb Symp Quant Biol 82:249. https:\/\/doi.org\/10.1101\/SQB.2017.82.034298","journal-title":"Cold Spring Harb Symp Quant Biol"},{"key":"9781_CR30","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1111\/J.1745-7262.2008.00410.X","volume":"10","author":"Y Li","year":"2008","unstructured":"Li Y, Lalancette C, Miller D, Krawetz SA (2008) Characterization of nucleohistone and nucleoprotamine components in the mature human sperm nucleus. Asian J Androl 10:535\u2013541. https:\/\/doi.org\/10.1111\/J.1745-7262.2008.00410.X","journal-title":"Asian J Androl"},{"key":"9781_CR31","doi-asserted-by":"publisher","unstructured":"Manske G, Jorgensen K, Ma B, et al (2022) Equalizing epigenetically imprinted centromeres in early mammalian embryos. bioRxiv 2022.10.27.514094. https:\/\/doi.org\/10.1101\/2022.10.27.514094","DOI":"10.1101\/2022.10.27.514094"},{"issue":"1","key":"9781_CR32","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1038\/nrm.2015.5","volume":"17","author":"KL McKinley","year":"2015","unstructured":"McKinley KL, Cheeseman IM (2015) The molecular basis for centromere identity and function. Nature Rev Mol Cell Biol 17(1):16\u201329. https:\/\/doi.org\/10.1038\/nrm.2015.5","journal-title":"Nature Rev Mol Cell Biol"},{"key":"9781_CR33","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/S1472-6483(10)61936-0","volume":"4","author":"YJR M\u00e9n\u00e9zo","year":"2002","unstructured":"M\u00e9n\u00e9zo YJR, H\u00e9rubel F (2002) Mouse and bovine models for human IVF. Reprod Biomed Online 4:170\u2013175. https:\/\/doi.org\/10.1016\/S1472-6483(10)61936-0","journal-title":"Reprod Biomed Online"},{"key":"9781_CR34","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1146\/ANNUREV-GENET-071719-020519\/1","volume":"55","author":"KH Miga","year":"2021","unstructured":"Miga KH, Alexandrov IA (2021) Variation and evolution of human centromeres: a field guide and perspective. Annu Rev Genet 55:583\u2013602. https:\/\/doi.org\/10.1146\/ANNUREV-GENET-071719-020519\/1","journal-title":"Annu Rev Genet"},{"key":"9781_CR35","doi-asserted-by":"publisher","unstructured":"Moens PB, Pearlman RE, Bazett-Jones DP (1990) Telomere and centromere DNA are associated with the cores of meiotic prophase chromosomes. Chromosoma 100: 8\u201314. https:\/\/doi.org\/10.1007\/BF00337598","DOI":"10.1007\/BF00337598"},{"key":"9781_CR36","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1071\/RD08269","volume":"21","author":"O Mudrak","year":"2009","unstructured":"Mudrak O, Chandra R, Jones E et al (2009) Reorganisation of human sperm nuclear architecture during formation of pronuclei in a model system. Reprod Fertil Dev 21:665\u2013671. https:\/\/doi.org\/10.1071\/RD08269","journal-title":"Reprod Fertil Dev"},{"issue":"1","key":"9781_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-024-52384-5","volume":"15","author":"TA Olagunju","year":"2024","unstructured":"Olagunju TA, Rosen BD, Neibergs HL et al (2024) Telomere-to-telomere assemblies of cattle and sheep Y-chromosomes uncover divergent structure and gene content. Nature Commun 15(1):1\u201312. https:\/\/doi.org\/10.1038\/s41467-024-52384-5","journal-title":"Nature Commun"},{"key":"9781_CR38","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1007\/BF00337600\/METRICS","volume":"100","author":"DK Palmer","year":"1990","unstructured":"Palmer DK, O\u2019Day K, Margolis RL (1990) The centromere specific histone CENP-A is selectively retained in discrete foci in mammalian sperm nuclei. Chromosoma 100:32\u201336. https:\/\/doi.org\/10.1007\/BF00337600\/METRICS","journal-title":"Chromosoma"},{"key":"9781_CR39","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1159\/000057002","volume":"93","author":"C Pfeifer","year":"2001","unstructured":"Pfeifer C, Thomsen PD, Scherthan H (2001) Centromere and telomere redistribution precedes homologue pairing and terminal synapsis initiation during prophase I of cattle spermatogenesis. Cytogenet Cell Genet 93:304\u2013314. https:\/\/doi.org\/10.1159\/000057002","journal-title":"Cytogenet Cell Genet"},{"key":"9781_CR40","unstructured":"Posit Team (2025) RStudio: Integrated development environment for R. Posit Software, PBC, Boston, MA. http:\/\/www.posit.co\/"},{"key":"9781_CR41","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.97.1.185","author":"D Powell","year":"1990","unstructured":"Powell D, Cran DG, Jennings C, Jones R (1990) Spatial organization of repetitive DNA sequences in the bovine sperm nucleus. J Cell Sci. https:\/\/doi.org\/10.1242\/jcs.97.1.185","journal-title":"J Cell Sci"},{"key":"9781_CR42","unstructured":"R Core Team (2025). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. https:\/\/www.R-project.org"},{"key":"9781_CR43","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1042\/BST20200267","volume":"50","author":"R Ranjan","year":"2022","unstructured":"Ranjan R, Chen X (2022) Mitotic drive in asymmetric epigenetic inheritance. Biochem Soc Trans 50:675\u2013688. https:\/\/doi.org\/10.1042\/BST20200267","journal-title":"Biochem Soc Trans"},{"key":"9781_CR44","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1016\/j.stem.2019.08.014","volume":"25","author":"R Ranjan","year":"2019","unstructured":"Ranjan R, Snedeker J, Chen X (2019) Asymmetric centromeres differentially coordinate with mitotic machinery to ensure biased sister chromatid segregation in germline stem cells. Cell Stem Cell 25:666-681.e5. https:\/\/doi.org\/10.1016\/j.stem.2019.08.014","journal-title":"Cell Stem Cell"},{"key":"9781_CR45","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001434","author":"N Raychaudhuri","year":"2012","unstructured":"Raychaudhuri N, Dubruille R, Orsi GA et al (2012) Transgenerational propagation and quantitative maintenance of paternal centromeres depends on Cid\/Cenp-A presence in Drosophila sperm. PLoS Biol. https:\/\/doi.org\/10.1371\/journal.pbio.1001434","journal-title":"PLoS Biol"},{"key":"9781_CR46","doi-asserted-by":"publisher","first-page":"907120","DOI":"10.3389\/FCELL.2022.907120\/XML\/NLM","volume":"10","author":"C Renaud-Pageot","year":"2022","unstructured":"Renaud-Pageot C, Quivy JP, Lochhead M, Almouzni G (2022) CENP-A regulation and cancer. Front Cell Dev Biol 10:907120. https:\/\/doi.org\/10.3389\/FCELL.2022.907120\/XML\/NLM","journal-title":"Front Cell Dev Biol"},{"key":"9781_CR47","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1038\/35085086","volume":"2","author":"H Scherthan","year":"2001","unstructured":"Scherthan H (2001) A bouquet makes ends meet. Nat Rev Mol Cell Biol 2:621\u2013627. https:\/\/doi.org\/10.1038\/35085086","journal-title":"Nat Rev Mol Cell Biol"},{"key":"9781_CR48","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1083\/JCB.134.5.1109","volume":"134","author":"H Scherthan","year":"1996","unstructured":"Scherthan H, Weich S, Schwegler H et al (1996) Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairing. J Cell Biol 134:1109\u20131125. https:\/\/doi.org\/10.1083\/JCB.134.5.1109","journal-title":"J Cell Biol"},{"key":"9781_CR49","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1016\/J.MOLCEL.2024.12.018","volume":"85","author":"S Sikder","year":"2025","unstructured":"Sikder S, Baek S, McNeil T, Dalal Y (2025) Centromere inactivation during aging can be rescued in human cells. Mol Cell 85:692-707.e7. https:\/\/doi.org\/10.1016\/J.MOLCEL.2024.12.018","journal-title":"Mol Cell"},{"key":"9781_CR50","doi-asserted-by":"publisher","first-page":"s27","DOI":"10.1017\/S1751731118000435","volume":"12","author":"C Staub","year":"2018","unstructured":"Staub C, Johnson L (2018) Review: spermatogenesis in the bull. Animal 12:s27\u2013s35. https:\/\/doi.org\/10.1017\/S1751731118000435","journal-title":"Animal"},{"key":"9781_CR51","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1007\/S00018-012-1048-8\/FIGURES\/6","volume":"70","author":"ME Stellfox","year":"2013","unstructured":"Stellfox ME, Bailey AO, Foltz DR (2013) Putting CENP-A in its place. Cell Mol Life Sci 70:387\u2013406. https:\/\/doi.org\/10.1007\/S00018-012-1048-8\/FIGURES\/6","journal-title":"Cell Mol Life Sci"},{"key":"9781_CR52","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/S10577-025-09766-2\/FIGURES\/2","volume":"33","author":"M \u0160tiavnick\u00e1","year":"2025","unstructured":"\u0160tiavnick\u00e1 M, Keegan RS, Dunleavy EM (2025) Marking dad\u2019s centromeres: maintaining CENP-A in sperm. Chromosome Res 33:1\u20139. https:\/\/doi.org\/10.1007\/S10577-025-09766-2\/FIGURES\/2","journal-title":"Chromosome Res"},{"key":"9781_CR53","doi-asserted-by":"publisher","first-page":"558","DOI":"10.15232\/PAS.2018-01748","volume":"34","author":"SK Thompson","year":"2018","unstructured":"Thompson SK, Kutchy NA, Kwok S et al (2018) Review: sperm: comparative morphology and function related to altered reproductive strategies and fertility in mammals. Prof Anim Sci 34:558\u2013565. https:\/\/doi.org\/10.15232\/PAS.2018-01748","journal-title":"Prof Anim Sci"},{"key":"9781_CR54","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1146\/ANNUREV-GENET-072920-125226\/CITE\/REFWORKS","volume":"56","author":"JA Urban","year":"2022","unstructured":"Urban JA, Ranjan R, Chen X (2022) Asymmetric histone inheritance: establishment, recognition, and execution. Annu Rev Genet 56:113\u2013143. https:\/\/doi.org\/10.1146\/ANNUREV-GENET-072920-125226\/CITE\/REFWORKS","journal-title":"Annu Rev Genet"},{"issue":"43","key":"9781_CR55","doi-asserted-by":"publisher","DOI":"10.21105\/joss.01686","volume":"4","author":"H Wickham","year":"2019","unstructured":"Wickham H, Averick M, Bryan J et al (2019) Welcome to the tidyverse. J Open Source Softw 4(43):1686. https:\/\/doi.org\/10.21105\/joss.01686","journal-title":"J Open Source Softw"},{"key":"9781_CR56","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-24277-4","volume-title":"ggplot2: Elegant graphics for data analysis","author":"H Wickham","year":"2016","unstructured":"Wickham H (2016) ggplot2: Elegant graphics for data analysis. Springer-Verlag, New York"},{"key":"9781_CR57","doi-asserted-by":"publisher","DOI":"10.1038\/srep31614","author":"E Wiland","year":"2016","unstructured":"Wiland E, Fraczek M, Olszewska M, Kurpisz M (2016) Topology of chromosome centromeres in human sperm nuclei with high levels of DNA damage. Sci Rep. https:\/\/doi.org\/10.1038\/srep31614","journal-title":"Sci Rep"},{"key":"9781_CR58","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-59055-z","author":"H Xu","year":"2025","unstructured":"Xu H, Chi Y, Yin C et al (2025) Three-dimensional genome structures of single mammalian sperm. Nat Commun. https:\/\/doi.org\/10.1038\/s41467-025-59055-z","journal-title":"Nat Commun"},{"key":"9781_CR59","doi-asserted-by":"publisher","first-page":"931222","DOI":"10.3389\/FGENE.2022.931222\/FULL","volume":"13","author":"Y Yang","year":"2022","unstructured":"Yang Y, Duan M, Zha Y, Wu Z (2022) CENP-A is a potential prognostic biomarker and correlated with immune infiltration levels in glioma patients. Front Genet 13:931222. https:\/\/doi.org\/10.3389\/FGENE.2022.931222\/FULL","journal-title":"Front Genet"},{"key":"9781_CR60","doi-asserted-by":"publisher","DOI":"10.1016\/J.SBI.2023.102638","volume":"81","author":"S Yatskevich","year":"2023","unstructured":"Yatskevich S, Barford D, Muir KW (2023) Conserved and divergent mechanisms of inner kinetochore assembly onto centromeric chromatin. Curr Opin Struct Biol 81:102638. https:\/\/doi.org\/10.1016\/J.SBI.2023.102638","journal-title":"Curr Opin Struct Biol"},{"key":"9781_CR61","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1007\/BF00368344","volume":"102","author":"AO Zalensky","year":"1993","unstructured":"Zalensky AO, Breneman JW, Zalenskaya IA et al (1993) Organization of centromeres in the decondensed nuclei of mature human sperm. Chromosoma 102:509\u201318. https:\/\/doi.org\/10.1007\/BF00368344","journal-title":"Chromosoma"},{"key":"9781_CR62","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1007\/BF00357684","volume":"103","author":"AO Zalensky","year":"1995","unstructured":"Zalensky AO, Allen MJ, Kobayashi A et al (1995) Well-defined genome architecture in the human sperm nucleus. Chromosoma 103:577\u2013590. https:\/\/doi.org\/10.1007\/BF00357684","journal-title":"Chromosoma"},{"key":"9781_CR63","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1146\/ANNUREV-GENET-061323-044915","volume":"57","author":"D Zickler","year":"2023","unstructured":"Zickler D, Kleckner N (2023) Meiosis: dances between homologs. Annu Rev Genet 57:1\u201363. https:\/\/doi.org\/10.1146\/ANNUREV-GENET-061323-044915","journal-title":"Annu Rev Genet"}],"container-title":["Chromosome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10577-025-09781-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10577-025-09781-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10577-025-09781-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T09:59:34Z","timestamp":1769248774000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10577-025-09781-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,16]]},"references-count":63,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["9781"],"URL":"https:\/\/doi.org\/10.1007\/s10577-025-09781-3","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-6929623\/v1","asserted-by":"object"}]},"ISSN":["1573-6849"],"issn-type":[{"value":"1573-6849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,16]]},"assertion":[{"value":"19 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 August 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 September 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}}],"article-number":"20"}}