{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T19:46:32Z","timestamp":1785095192957,"version":"3.55.0"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T00:00:00Z","timestamp":1586822400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T00:00:00Z","timestamp":1586822400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Child Psychiatry Hum Dev"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1007\/s10578-020-00989-4","type":"journal-article","created":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T13:02:37Z","timestamp":1586869357000},"page":"77-95","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["A Systematic Review and Meta-Analysis of the Risk of Disruptive Behavioral Disorders in the Offspring of Parents with Severe Psychiatric Disorders"],"prefix":"10.1007","volume":"52","author":[{"given":"Getinet","family":"Ayano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Betts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joemer Calderon","family":"Maravilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Alati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,4,14]]},"reference":[{"key":"989_CR1","unstructured":"Diagnostic and statistical manual of mental disorders-IV-TR (2000) Washington American Psychiatric Association American Psychiatric Association DC"},{"key":"989_CR2","unstructured":"Diagnostic Stastistical Manual of Mental Disorder (5th edition). Wahington, DC: American Psychiatric Association; American Psychiatric Association, (2013)"},{"issue":"1","key":"989_CR3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.5409\/wjcp.v7.i1.9","volume":"7","author":"MO Ogundele","year":"2018","unstructured":"Ogundele MO (2018) Behavioural and emotional disorders in childhood: a brief overview for paediatricians. World J Clin Pediatr 7(1):9\u201326","journal-title":"World J Clin Pediatr"},{"issue":"7","key":"989_CR4","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1017\/S0033291707002668","volume":"38","author":"J Biederman","year":"2008","unstructured":"Biederman J, Petty CR, Dolan C, Hughes S, Mick E, Monuteaux MC, Faraone SV (2008) The long-term longitudinal course of oppositional defiant disorder and conduct disorder in ADHD boys: findings from a controlled 10-year prospective longitudinal follow-up study. Psychol Med 38(7):1027\u20131036","journal-title":"Psychol Med"},{"issue":"3","key":"989_CR5","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1901\/jaba.1991.24-523","volume":"24","author":"EG Carr","year":"1991","unstructured":"Carr EG, Taylor JC, Robinson S (1991) The effects of severe behavior problems in children on the teaching behavior of adults. J Appl Behav Anal 24(3):523\u2013535","journal-title":"J Appl Behav Anal"},{"issue":"1","key":"989_CR6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s12991-020-00271-w","volume":"19","author":"G Ayano","year":"2020","unstructured":"Ayano G, Yohannes K, Abraha M (2020) Epidemiology of attention-deficit\/hyperactivity disorder (ADHD) in children and adolescents in Africa: a systematic review and meta-analysis. Ann Gen Psychiatry 19(1):21","journal-title":"Ann Gen Psychiatry"},{"key":"989_CR7","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/j.1469-7610.2007.01733.x","volume":"48","author":"MK Nock","year":"2007","unstructured":"Nock MK, Kazdin AE, Hiripi E, Kessler RC (2007) Lifetime prevalence, correlates, and persistence of oppositional defiant disorder: results from the National Comorbidity Survey Replication. J Child Psychol Psychiatry 48:703\u2013713","journal-title":"J Child Psychol Psychiatry"},{"issue":"12","key":"989_CR8","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1111\/jcpp.12144","volume":"54","author":"HE Erskine","year":"2013","unstructured":"Erskine HE, Ferrari AJ, Nelson P, Polanczyk GV, Flaxman AD, Vos T, Whiteford HA, Scott JG (2013) Epidemiological modelling of attention-deficit\/hyperactivity disorder and conduct disorder for the Global Burden of Disease Study 2010. J Child Psychol Psychiatry 54(12):1263\u20131274","journal-title":"J Child Psychol Psychiatry"},{"issue":"3","key":"989_CR9","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/1469-7610.00027","volume":"43","author":"R Rowe","year":"2002","unstructured":"Rowe R, Maughan B, Pickles A, Costello EJ, Angold A (2002) Psychiatry: the relationship between DSM-IV oppositional defiant disorder and conduct disorder: findings from the Great Smoky Mountains Study. J Child Psychol Psychiatry 43(3):365\u2013373","journal-title":"J Child Psychol Psychiatry"},{"issue":"7","key":"989_CR10","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1176\/appi.ajp.159.7.1214","volume":"159","author":"RW Greene","year":"2002","unstructured":"Greene RW, Biederman J, Zerwas S, Monuteaux MC, Goring JC, Faraone SV (2002) Psychiatric comorbidity, family dysfunction, and social impairment in referred youth with oppositional defiant disorder. Am J Psychiatry 159(7):1214\u20131224","journal-title":"Am J Psychiatry"},{"issue":"4","key":"989_CR11","doi-asserted-by":"crossref","first-page":"240","DOI":"10.3109\/08039488.2012.731431","volume":"67","author":"T Nordstrom","year":"2013","unstructured":"Nordstrom T, Ebeling H, Hurtig T, Rodriguez A, Savolainen J, Moilanen I, Taanila A (2013) Comorbidity of disruptive behavioral disorders and attention-deficit hyperactivity disorder\u2013indicator of severity in problematic behavior? Nord J Psychiatry 67(4):240\u2013248","journal-title":"Nord J Psychiatry"},{"issue":"4","key":"989_CR12","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1111\/j.1943-278X.2012.00101.x","volume":"42","author":"J Linker","year":"2012","unstructured":"Linker J, Gillespie NA, Maes H, Eaves L, Silberg JL (2012) Suicidal ideation, depression, and conduct disorder in a sample of adolescent and young adult twins. Suicide Life Threat Behav 42(4):426\u2013436","journal-title":"Suicide Life Threat Behav"},{"issue":"8","key":"989_CR13","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.janxdis.2011.07.001","volume":"25","author":"D Teubert","year":"2011","unstructured":"Teubert D, Pinquart M (2011) A meta-analytic review on the prevention of symptoms of anxiety in children and adolescents. J Anxiety Disord 25(8):1046\u20131059","journal-title":"J Anxiety Disord"},{"key":"989_CR14","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.invent.2016.05.001","volume":"4","author":"AJ Morgan","year":"2016","unstructured":"Morgan AJ, Rapee RM, Bayer JK (2016) Prevention and early intervention of anxiety problems in young children: a pilot evaluation of Cool Little Kids Online. Internet Interv 4:105\u2013112","journal-title":"Internet Interv"},{"issue":"1","key":"989_CR15","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1093\/schbul\/sbt114","volume":"40","author":"D Rasic","year":"2014","unstructured":"Rasic D, Hajek T, Alda M, Uher R (2014) Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: a meta-analysis of family high-risk studies. Schizophr Bull 40(1):28\u201338","journal-title":"Schizophr Bull"},{"issue":"3 Suppl","key":"989_CR16","first-page":"S7","volume":"199","author":"AE Reupert","year":"2013","unstructured":"Reupert AE (2013) D JM, Kowalenko NM: Children whose parents have a mental illness: prevalence, need and treatment. Med J Aust 199(3 Suppl):S7\u20139","journal-title":"Med J Aust"},{"issue":"7","key":"989_CR17","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00787-017-1050-7","volume":"27","author":"P Lau","year":"2018","unstructured":"Lau P, Hawes DJ, Hunt C, Frankland A, Roberts G, Mitchell PB (2018) Prevalence of psychopathology in bipolar high-risk offspring and siblings: a meta-analysis. Eur Child Adolesc Psychiatry 27(7):823\u2013837","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"989_CR18","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jad.2019.01.038","volume":"248","author":"G Ayano","year":"2019","unstructured":"Ayano G, Maravilla JC, Alati R (2019) Risk of autistic spectrum disorder in offspring with parental mood disorders: a systematic review and meta-analysis. J Affect Disord 248:185\u2013197","journal-title":"J Affect Disord"},{"key":"989_CR19","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jpsychires.2015.01.017","volume":"62","author":"T Perich","year":"2015","unstructured":"Perich T, Lau P, Hadzi-Pavlovic D, Roberts G, Frankland A, Wright A, Green M, Breakspear M, Corry J, Radlinska B et al (2015) What clinical features precede the onset of bipolar disorder? J Psychiatr Res 62:71\u201377","journal-title":"J Psychiatr Res"},{"issue":"9","key":"989_CR20","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1038\/ng.2711","volume":"45","author":"SH Lee","year":"2013","unstructured":"Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS (2013) Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet 45(9):984","journal-title":"Nat Genet"},{"issue":"1","key":"989_CR21","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1006\/drev.1997.0448","volume":"18","author":"PK Coleman","year":"1998","unstructured":"Coleman PK, Karraker KH (1998) (1998) Self-efficacy and parenting quality: findings and future applications. Dev Rev 18(1):47\u201385","journal-title":"Dev Rev"},{"issue":"3","key":"989_CR22","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1037\/0033-2909.113.3.487","volume":"113","author":"N Darling","year":"1993","unstructured":"Darling N, Steinberg L (1993) Parenting style as context: An integrative model. Psychol Bull 113(3):487\u2013496","journal-title":"Psychol Bull"},{"key":"989_CR23","doi-asserted-by":"crossref","unstructured":"Hammen C (1997) Children of depressed parents. In: Handbook of children\u2019s coping. Springer, 131\u2013157.","DOI":"10.1007\/978-1-4757-2677-0_5"},{"issue":"3","key":"989_CR24","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1037\/h0087733","volume":"70","author":"D Oyserman","year":"2000","unstructured":"Oyserman D, Mowbray CT, Meares PA, Firminger KB (2000) Parenting among mothers with a serious mental illness. Am J Orthopsychiatry 70(3):296\u2013315","journal-title":"Am J Orthopsychiatry"},{"issue":"2","key":"989_CR25","doi-asserted-by":"crossref","first-page":"562","DOI":"10.2307\/1131402","volume":"65","author":"VC McLoyd","year":"1994","unstructured":"McLoyd VC, Jayaratne TE, Ceballo R, Borquez J (1994) Unemployment and work interruption among African American single mothers: effects on parenting and adolescent socioemotional functioning. Child Dev 65(2):562\u2013589","journal-title":"Child Dev"},{"issue":"7","key":"989_CR26","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.biopsych.2005.06.010","volume":"58","author":"A Henin","year":"2005","unstructured":"Henin A, Biederman J, Mick E, Sachs GS, Hirshfeld-Becker DR, Siegel RS, McMurrich S, Grandin L, Nierenberg AA (2005) Psychopathology in the offspring of parents with bipolar disorder: a controlled study. Biol Psychiatry 58(7):554\u2013561","journal-title":"Biol Psychiatry"},{"issue":"1\u20132","key":"989_CR27","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jad.2011.09.002","volume":"136","author":"B Mars","year":"2012","unstructured":"Mars B, Collishaw S, Smith D, Thapar A, Potter R, Sellers R, Harold GT, Craddock N, Rice F, Thapar A (2012) Offspring of parents with recurrent depression: which features of parent depression index risk for offspring psychopathology? J Affect Disord 136(1\u20132):44\u201353","journal-title":"J Affect Disord"},{"issue":"10","key":"989_CR28","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1001\/archgenpsychiatry.2011.126","volume":"68","author":"JI Nurnberger","year":"2011","unstructured":"Nurnberger JI, Mcinnis M, Reich W, Kastelic E, Wilcox HC, Glowinski A, Mitchell P, Fisher C, Erpe M, Gershon ES, Berrettini W, Laite G, Schweitzer R, Rhoadarmer K, Coleman VV, Cai X, Azzouz F, Liu H, Kamali M, Brucksch C, Monahan PO (2011) A high-risk study of bipolar disorder: childhood clinical phenotypes as precursors of major mood disorders. Arch Gen Psychiatry 68(10):1012\u20131020","journal-title":"Arch Gen Psychiatry"},{"issue":"2","key":"989_CR29","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/oxfordjournals.schbul.a007080","volume":"30","author":"SL Hans","year":"2004","unstructured":"Hans SL, Auerbach JG, Styr B, Marcus J (2004) Offspring of parents with schizophrenia: mental disorders during childhood and adolescence. Schizophr Bull 30(2):303\u2013315","journal-title":"Schizophr Bull"},{"key":"989_CR30","unstructured":"Reviews UoYCf, Dissemination: Systematic reviews: CRD's guidance for undertaking reviews in health care: University of York, Centre for Reviews & Dissemination; 2009."},{"issue":"7","key":"989_CR31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pmed.1000097","volume":"6","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6(7):1\u20136","journal-title":"PLoS Med"},{"key":"989_CR32","unstructured":"Wells G: Wells GA, Shea B, O'Connell D, Peterson J, Welch V, Losos M, et al. (2011) The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses"},{"issue":"1","key":"989_CR33","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","volume":"33","author":"JR Landis","year":"1977","unstructured":"Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33(1):159\u2013174","journal-title":"Biometrics"},{"key":"989_CR34","unstructured":"Samuel B. Guze (1995) diagnostic and statistical manual of mental disorders, 4th ed. (DSM-IV), 152(8):1228\u20131228"},{"key":"989_CR35","unstructured":"Pichot P (1986) [DSM-III: the 3d edition of the Diagnostic and Statistical Manual of Mental Disorders from the American Psychiatric Association]. Revue neurologique, 142(5):489\u2013499."},{"key":"989_CR36","first-page":"104","volume-title":"Comprehensive meta-analysis version 2","author":"M Borenstein","year":"2005","unstructured":"Borenstein M, Hedges L, Higgins J, Rothstein H (2005) Comprehensive meta-analysis version 2. Biostat, Englewood, NJ, p 104"},{"issue":"2","key":"989_CR37","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/jrsm.12","volume":"1","author":"M Borenstein","year":"2010","unstructured":"Borenstein M, Hedges LV, Higgins J, Rothstein HR (2010) A basic introduction to fixed-effect and random-effects models for meta-analysis. Res Synth Methods 1(2):97\u2013111","journal-title":"Res Synth Methods"},{"issue":"7414","key":"989_CR38","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"JP Higgins","year":"2003","unstructured":"Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ Br Med J 327(7414):557","journal-title":"BMJ Br Med J"},{"issue":"5","key":"989_CR39","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1093\/ije\/dyn065","volume":"37","author":"NA Patsopoulos","year":"2008","unstructured":"Patsopoulos NA, Evangelou E, Ioannidis JP (2008) Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation. Int J Epidemiol 37(5):1148\u20131157","journal-title":"Int J Epidemiol"},{"issue":"7109","key":"989_CR40","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"M Egger","year":"1997","unstructured":"Egger M, Smith GD, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315(7109):629\u2013634","journal-title":"BMJ"},{"issue":"4 Pt 1","key":"989_CR41","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1017\/S0954579413000369","volume":"25","author":"C Glasheen","year":"2013","unstructured":"Glasheen C, Richardson GA, Kim KH, Larkby CA, Swartz HA, Day NL (2013) Exposure to maternal pre- and postnatal depression and anxiety symptoms: risk for major depression, anxiety disorders, and conduct disorder in adolescent offspring. Dev Psychopathol 25(4 Pt 1):1045\u20131063","journal-title":"Dev Psychopathol"},{"issue":"10","key":"989_CR42","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1001\/archgenpsychiatry.2011.126","volume":"68","author":"JI Nurnberger","year":"2011","unstructured":"Nurnberger JI, McInnis M, Reich W, Kastelic E, Wilcox HC, Glowinski A, Mitchell P, Fisher C, Erpe M, Gershon ES et al (2011) A high-risk study of bipolar disorder: childhood clinical phenotypes as precursors of major mood disorders. Arch Gen Psychiatry 68(10):1012\u20131020","journal-title":"Arch Gen Psychiatry"},{"issue":"1\u20133","key":"989_CR43","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jad.2006.06.010","volume":"97","author":"SL Halligan","year":"2007","unstructured":"Halligan SL, Murray L, Martins C, Cooper PJ (2007) Maternal depression and psychiatric outcomes in adolescent offspring: a 13-year longitudinal study. J Affect Disord 97(1\u20133):145\u2013154","journal-title":"J Affect Disord"},{"issue":"3","key":"989_CR44","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1001\/archgenpsychiatry.2008.546","volume":"66","author":"B Birmaher","year":"2009","unstructured":"Birmaher B, Axelson D, Monk K, Kalas C, Goldstein B, Hickey MB, Obreja M, Ehmann M, Iyengar S, Shamseddeen W et al (2009) Lifetime psychiatric disorders in school-aged offspring of parents with bipolar disorder: the pittsburgh bipolar offspring study. Arch Gen Psychiatry 66(3):287\u2013296","journal-title":"Arch Gen Psychiatry"},{"issue":"6","key":"989_CR45","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1089\/cap.2016.0056","volume":"27","author":"M Goetz","year":"2017","unstructured":"Goetz M, Sebela A, Mohaplova M, Ceresnakova S, Ptacek R, Novak T (2017) Psychiatric disorders and quality of life in the offspring of parents with bipolar disorder. J Child Adolesc Psychopharmacol 27(6):483\u2013493","journal-title":"J Child Adolesc Psychopharmacol"},{"issue":"2","key":"989_CR46","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/jcpp.12137","volume":"55","author":"H Maoz","year":"2014","unstructured":"Maoz H, Goldstein T, Axelson DA, Goldstein BI, Fan J, Hickey MB, Monk K, Sakolsky D, Diler RS, Brent D et al (2014) Dimensional psychopathology in preschool offspring of parents with bipolar disorder. J Child Psychol Psychiatry 55(2):144\u2013153","journal-title":"J Child Psychol Psychiatry"},{"issue":"2\u20133","key":"989_CR47","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.psychres.2005.08.026","volume":"145","author":"DR Hirshfeld-Becker","year":"2006","unstructured":"Hirshfeld-Becker DR, Biederman J, Henin A, Faraone SV, Dowd ST, De Petrillo LA, Markowitz SM, Rosenbaum JF (2006) Psychopathology in the young offspring of parents with bipolar disorder: a controlled pilot study. Psychiatry Res 145(2\u20133):155\u2013167","journal-title":"Psychiatry Res"},{"issue":"4","key":"989_CR48","first-page":"388","volume":"49","author":"BI Goldstein","year":"2010","unstructured":"Goldstein BI, Shamseddeen W, Axelson DA, Kalas C, Monk K, Brent DA, Kupfer DJ, Birmaher B (2010) Clinical, demographic, and familial correlates of bipolar spectrum disorders among offspring of parents with bipolar disorder. J Am Acad Child Adolesc Psychiatry 49(4):388\u2013396","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"1\u20132","key":"989_CR49","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.schres.2015.08.034","volume":"168","author":"V Sanchez-Gistau","year":"2015","unstructured":"Sanchez-Gistau V, Romero S, Moreno D, de la Serna E, Baeza I, Sugranyes G, Moreno C, Sanchez-Gutierrez T, Rodriguez-Toscano E, Castro-Fornieles J (2015) Psychiatric disorders in child and adolescent offspring of patients with schizophrenia and bipolar disorder: a controlled study. Schizophr Res 168(1\u20132):197\u2013203","journal-title":"Schizophr Res"},{"issue":"5","key":"989_CR50","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.jaac.2011.02.001","volume":"50","author":"L Murray","year":"2011","unstructured":"Murray L, Arteche A, Fearon P, Halligan S, Goodyer I, Cooper P (2011) Maternal postnatal depression and the development of depression in offspring up to 16 years of age. J Am Acad Child Adolesc Psychiatry 50(5):460\u2013470","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"6","key":"989_CR51","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/j.1399-5618.2012.01048.x","volume":"14","author":"C Vandeleur","year":"2012","unstructured":"Vandeleur C, Rothen S, Gholam-Rezaee M, Castelao E, Vidal S, Favre S, Ferrero F, Halfon O, Fumeaux P, Merikangas KR et al (2012) Mental disorders in offspring of parents with bipolar and major depressive disorders. Bipolar Disord 14(6):641\u2013653","journal-title":"Bipolar Disord"},{"issue":"3","key":"989_CR52","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0165-0327(91)90039-U","volume":"21","author":"M Grigoroiu-Serbanescu","year":"1991","unstructured":"Grigoroiu-Serbanescu M, Christodorescu D, Magureanu S, Jipescu I, Totoescu A, Marinescu E, Ardelean V, Popa S (1991) Adolescent offspring of endogenous unipolar depressive parents and of normal parents. J Affect Disord 21(3):185\u2013198","journal-title":"J Affect Disord"},{"issue":"3","key":"989_CR53","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1017\/S0033291712001511","volume":"43","author":"A Ferrari","year":"2013","unstructured":"Ferrari A, Somerville A, Baxter A, Norman R, Patten S, Vos T, Whiteford HA (2013) Global variation in the prevalence and incidence of major depressive disorder: a systematic review of the epidemiological literature. Psychol Med 43(3):471\u2013481","journal-title":"Psychol Med"},{"issue":"4","key":"989_CR54","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/nrg2045","volume":"8","author":"RL Jirtle","year":"2007","unstructured":"Jirtle RL, Skinner MK (2007) Environmental epigenomics and disease susceptibility. Nat Rev Genet 8(4):253\u2013262","journal-title":"Nat Rev Genet"},{"issue":"8","key":"989_CR55","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1007\/s00438-012-0708-6","volume":"287","author":"AR Prickett","year":"2012","unstructured":"Prickett AR, Oakey RJ (2012) genomics: a survey of tissue-specific genomic imprinting in mammals. Mol Genet Genomics 287(8):621\u2013630","journal-title":"Mol Genet Genomics"},{"issue":"3","key":"989_CR56","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3390\/genes8030104","volume":"8","author":"M Kundakovic","year":"2017","unstructured":"Kundakovic M, Jaric I (2017) The epigenetic link between prenatal adverse environments and neurodevelopmental disorders. Genes (Basel) 8(3):104","journal-title":"Genes (Basel)"},{"issue":"1","key":"989_CR57","doi-asserted-by":"crossref","first-page":"25","DOI":"10.31887\/DCNS.2010.12.1\/cptak","volume":"12","author":"C Ptak","year":"2010","unstructured":"Ptak C, Petronis A (2010) Epigenetic approaches to psychiatric disorders. Dialogues Clin Neurosci 12(1):25\u201335","journal-title":"Dialogues Clin Neurosci"},{"issue":"5","key":"989_CR58","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1177\/1073858415608147","volume":"22","author":"EJ Nestler","year":"2016","unstructured":"Nestler EJ, Pena CJ, Kundakovic M, Mitchell A, Akbarian S (2016) Epigenetic basis of mental illness. The Neuroscientist 22(5):447\u2013463","journal-title":"The Neuroscientist"},{"issue":"10","key":"989_CR59","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1007\/s00787-015-0677-5","volume":"24","author":"AK Knudsen","year":"2015","unstructured":"Knudsen AK, Ystrom E, Skogen JC, Torgersen L (2015) Maternal heavy alcohol use and toddler behavior problems: a fixed effects regression analysis. Eur Child Adolesc Psychiatry 24(10):1269\u20131277","journal-title":"Eur Child Adolesc Psychiatry"},{"issue":"3","key":"989_CR60","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s10802-006-9021-3","volume":"34","author":"EP Edwards","year":"2006","unstructured":"Edwards EP, Eiden RD, Colder C, Leonard KE (2006) The development of aggression in 18 to 48 month old children of alcoholic parents. J Abnorm Child Psychol 34(3):393\u2013407","journal-title":"J Abnorm Child Psychol"},{"issue":"3\u20134","key":"989_CR61","first-page":"89","volume":"2","author":"N Parvaresh","year":"2010","unstructured":"Parvaresh N, Ziaaddini H, Kheradmand A, Bayati H (2010) Attention deficit hyperactivity disorder (ADHD) and conduct disorder in children of drug dependent parents. Addict Health 2(3\u20134):89\u201394","journal-title":"Addict Health"},{"issue":"2","key":"989_CR62","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1089\/cap.2015.0074","volume":"26","author":"SD Mayes","year":"2016","unstructured":"Mayes SD, Waxmonsky JD, Calhoun SL, Bixler EO (2016) Disruptive mood dysregulation disorder symptoms and association with oppositional defiant and other disorders in a general population child sample. J Child Adolesc Psychopharmacol 26(2):101\u2013106","journal-title":"J Child Adolesc Psychopharmacol"},{"issue":"1","key":"989_CR63","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jad.2009.11.006","volume":"126","author":"M Cerd\u00e1","year":"2010","unstructured":"Cerd\u00e1 M, Sagdeo A, Johnson J, Galea S (2010) Genetic and environmental influences on psychiatric comorbidity: a systematic review. J Affect Disord 126(1):14\u201338","journal-title":"J Affect Disord"},{"issue":"4","key":"989_CR64","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1023\/A:1025708318528","volume":"25","author":"H Gjone","year":"1997","unstructured":"Gjone H, Stevenson J (1997) The association between internalizing and externalizing behavior in childhood and early adolescence: genetic or environmental common influences? J Abnorm Child Psychol 25(4):277\u2013286","journal-title":"J Abnorm Child Psychol"},{"issue":"9","key":"989_CR65","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.annepidem.2014.05.010","volume":"24","author":"BM McCoy","year":"2014","unstructured":"McCoy BM, Rickert ME, Class QA, Larsson H, Lichtenstein P, Donofrio BM (2014) Mediators of the association between parental severe mental illness and offspring neurodevelopmental problems. Ann Epidemiol 24(9):629\u2013634","journal-title":"Ann Epidemiol"},{"issue":"3","key":"989_CR66","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1399-5618.2007.00382.x","volume":"9","author":"JH MacCabe","year":"2007","unstructured":"MacCabe JH, Martinsson L, Lichtenstein P, Nilsson E, Cnattingius S, Murray RM, Hultman CM (2007) Adverse pregnancy outcomes in mothers with affective psychosis. Bipolar Disord 9(3):305\u2013309","journal-title":"Bipolar Disord"},{"issue":"4","key":"989_CR67","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1192\/bjp.bp.107.045146","volume":"193","author":"E Nilsson","year":"2018","unstructured":"Nilsson E, Hultman CM, Cnattingius S, Olausson PO, Bj\u00f6rk C, Lichtenstein P (2018) Schizophrenia and offspring's risk for adverse pregnancy outcomes and infant death. Br J Psychiatry 193(4):311\u2013315","journal-title":"Br J Psychiatry"},{"issue":"2","key":"989_CR68","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0920-9964(01)00370-X","volume":"58","author":"E Nilsson","year":"2002","unstructured":"Nilsson E, Lichtenstein P, Cnattingius S, Murray RM, Hultman CM (2002) Women with schizophrenia: pregnancy outcome and infant death among their offspring. Schizophr Res 58(2):221\u2013229","journal-title":"Schizophr Res"},{"issue":"23","key":"989_CR69","first-page":"413","volume":"105","author":"F Mattejat","year":"2008","unstructured":"Mattejat F, Remschmidt H (2008) The children of mentally ill parents. Dtsch Arztebl Int 105(23):413\u2013418","journal-title":"Dtsch Arztebl Int"},{"issue":"3","key":"989_CR70","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/YCO.0b013e3283523dcc","volume":"25","author":"D Hasin","year":"2012","unstructured":"Hasin D, Kilcoyne B (2012) Comorbidity of psychiatric and substance use disorders in the United States: current issues and findings from the NESARC. Curr Opin Psychiatry 25(3):165\u2013171","journal-title":"Curr Opin Psychiatry"},{"issue":"3","key":"989_CR71","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1037\/ort0000063","volume":"85","author":"K Bountress","year":"2015","unstructured":"Bountress K, Chassin L (2015) Risk for behavior problems in children of parents with substance use disorders. Am J Orthopsychiatry 85(3):275\u2013286","journal-title":"Am J Orthopsychiatry"},{"issue":"12","key":"989_CR72","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1001\/archpsyc.59.12.1125","volume":"59","author":"Q Fu","year":"2002","unstructured":"Fu Q, Heath AC, Bucholz KK, Nelson E, Goldberg J, Lyons MJ, True WR, Jacob T, Tsuang MT, Eisen SA (2002) Shared genetic risk of major depression, alcohol dependence, and marijuana dependence: contribution of antisocial personality disorder in men. Arch Gen Psychiatry 59(12):1125\u20131132","journal-title":"Arch Gen Psychiatry"}],"container-title":["Child Psychiatry & Human Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10578-020-00989-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10578-020-00989-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10578-020-00989-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T00:18:52Z","timestamp":1618359532000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10578-020-00989-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,14]]},"references-count":72,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["989"],"URL":"https:\/\/doi.org\/10.1007\/s10578-020-00989-4","relation":{},"ISSN":["0009-398X","1573-3327"],"issn-type":[{"value":"0009-398X","type":"print"},{"value":"1573-3327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,14]]},"assertion":[{"value":"14 April 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"All authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}