{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T02:05:56Z","timestamp":1780106756093,"version":"3.54.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T00:00:00Z","timestamp":1595376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T00:00:00Z","timestamp":1595376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Exp Metastasis"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s10585-020-10052-0","type":"journal-article","created":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T09:07:50Z","timestamp":1595408870000},"page":"585-592","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Adrenal SBRT: a multi-institutional review of treatment outcomes and toxicity"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6097-7882","authenticated-orcid":false,"given":"Corbin A.","family":"Helis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan T.","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Nieto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adannia","family":"Ufondu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily C.","family":"Daugherty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael K.","family":"Farris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,22]]},"reference":[{"issue":"1","key":"10052_CR1","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1046\/j.0300-0664.2001.01435.x","volume":"56","author":"K-Y Lam","year":"2002","unstructured":"Lam K-Y, Lo C-Y (2002) Metastatic tumours of the adrenal glands: a 30-year experience in a teaching hospital. Clin Endocrinol 56(1):95\u2013101","journal-title":"Clin Endocrinol"},{"issue":"10185","key":"10052_CR2","doi-asserted-by":"publisher","first-page":"2051","DOI":"10.1016\/S0140-6736(18)32487-5","volume":"393","author":"DA Palma","year":"2019","unstructured":"Palma DA, Olson R, Harrow S et al (2019) Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open-label trial. Lancet 393(10185):2051\u20132058","journal-title":"Lancet"},{"issue":"18","key":"10052_CR3","doi-asserted-by":"publisher","first-page":"1558","DOI":"10.1200\/JCO.19.00201","volume":"37","author":"DR Gomez","year":"2019","unstructured":"Gomez DR, Tang C, Zhang J et al (2019) Local consolidative therapy vs maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer: long-term results of a multi-institutional, phase II, randomized study. J Clin Oncol 37(18):1558\u20131565","journal-title":"J Clin Oncol"},{"issue":"4","key":"10052_CR4","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/j.adro.2017.07.011","volume":"2","author":"K Plichta","year":"2017","unstructured":"Plichta K, Camden N, Furqan M et al (2017) SBRT to adrenal metastases provides high local control with minimal toxicity. Adv Radiat Oncol 2(4):581\u2013587","journal-title":"Adv Radiat Oncol"},{"issue":"4","key":"10052_CR5","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1016\/j.adro.2018.05.006","volume":"3","author":"DAS Toesca","year":"2018","unstructured":"Toesca DAS, Koong AJ, von Eyben R, Koong AC, Chang DT (2018) Stereotactic body radiation therapy for adrenal gland metastases: outcomes and toxicity. Adv Radiat Oncol 3(4):621\u2013629","journal-title":"Adv Radiat Oncol"},{"issue":"3","key":"10052_CR6","doi-asserted-by":"publisher","first-page":"e195","DOI":"10.1016\/j.prro.2016.09.005","volume":"7","author":"WW Chance","year":"2017","unstructured":"Chance WW, Nguyen Q-N, Mehran R et al (2017) Stereotactic ablative radiotherapy for adrenal gland metastases: factors influencing outcomes, patterns of failure, and dosimetric thresholds for toxicity. Pract Radiat Oncol 7(3):e195\u2013e203","journal-title":"Pract Radiat Oncol"},{"issue":"1","key":"10052_CR7","doi-asserted-by":"publisher","first-page":"20","DOI":"10.4143\/crt.2016.057","volume":"49","author":"C Franzese","year":"2017","unstructured":"Franzese C, Franceschini D, Cozzi L et al (2017) Minimally invasive stereotactical radio-ablation of adrenal metastases as an alternative to surgery. Cancer Res Treat 49(1):20\u201328","journal-title":"Cancer Res Treat"},{"issue":"1","key":"10052_CR8","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.ijrobp.2008.10.079","volume":"75","author":"S Chawla","year":"2009","unstructured":"Chawla S, Chen Y, Katz AW et al (2009) Stereotactic body radiotherapy for treatment of adrenal metastases. Int J Radiat Oncol Biol Phys 75(1):71\u201375","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10052_CR9","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1016\/j.ijrobp.2010.11.060","volume":"82","author":"F Casamassima","year":"2012","unstructured":"Casamassima F, Livi L, Masciullo S et al (2012) Stereotactic radiotherapy for adrenal gland metastases: university of Florence experience. Int J Radiat Oncol Biol Phys 82(2):919\u2013923","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"3","key":"10052_CR10","first-page":"e1120","volume":"9","author":"A Haidenberger","year":"2017","unstructured":"Haidenberger A, Heidorn S-C, Kremer N, Muacevic A, F\u00fcrweger C (2017) Robotic radiosurgery for adrenal gland metastases. Cureus 9(3):e1120","journal-title":"Cureus"},{"key":"10052_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2020.01.017","author":"WC Chen","year":"2020","unstructured":"Chen WC, Baal JD, Baal U et al (2020) Stereotactic body radiotherapy of adrenal metastases: a pooled meta-analysis and systematic review of 39 studies with 1006 patients. Int J Radiat Oncol Biol Phys. https:\/\/doi.org\/10.1016\/j.ijrobp.2020.01.017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10052_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/j.prro.2019.07.018","author":"A Oar","year":"2019","unstructured":"Oar A, Lee M, Le H et al (2019) Australasian Gastrointestinal Trials Group (AGITG) and Trans-Tasman Radiation Oncology Group (TROG) guidelines for pancreatic Stereotactic Body Radiation Therapy (SBRT). Pract Radiat Oncol. https:\/\/doi.org\/10.1016\/j.prro.2019.07.018","journal-title":"Pract Radiat Oncol"},{"key":"10052_CR13","first-page":"2","volume-title":"Gunderson and Tepper\u2019s Clinical Radiation Oncology","author":"EM Zeman","year":"2021","unstructured":"Zeman EM (2021) The Biological Basis of Radiation Oncology. In: Tepper JE, Foote RL, Michalski JM (eds) Gunderson and Tepper\u2019s Clinical Radiation Oncology, vol 1, 5th edn. Elsevier, Amsterdam, pp 2\u201338","edition":"5"},{"issue":"1","key":"10052_CR14","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1245\/s10434-014-3750-2","volume":"22","author":"A Hauch","year":"2015","unstructured":"Hauch A, Al-Qurayshi Z, Kandil E (2015) Factors associated with higher risk of complications after adrenal surgery. Ann Surg Oncol 22(1):103\u2013110. https:\/\/doi.org\/10.1245\/s10434-014-3750-2","journal-title":"Ann Surg Oncol"},{"issue":"7","key":"10052_CR15","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.1002\/cncr.20539","volume":"101","author":"H Onishi","year":"2004","unstructured":"Onishi H, Araki T, Shirato H et al (2004) Stereotactic hypofractionated high-dose irradiation for stage I nonsmall cell lung carcinoma: clinical outcomes in 245 subjects in a Japanese multiinstitutional study. Cancer 101(7):1623\u20131631","journal-title":"Cancer"},{"issue":"2","key":"10052_CR16","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1148\/radiol.2015142029","volume":"277","author":"T Hasegawa","year":"2015","unstructured":"Hasegawa T, Yamakado K, Nakatsuka A et al (2015) Unresectable adrenal metastases: clinical outcomes of radiofrequency ablation. Radiology 277(2):584\u2013593","journal-title":"Radiology"},{"issue":"17","key":"10052_CR17","doi-asserted-by":"publisher","first-page":"2027","DOI":"10.4103\/0366-6999.210496","volume":"130","author":"EI Botsa","year":"2017","unstructured":"Botsa EI, Thanou IL, Papatheodoropoulou AT, Thanos LI (2017) Thermal ablation in the management of adrenal metastasis originating from non-small cell lung cancer: a 5-year single-center experience. Chin Med J 130(17):2027\u20132032","journal-title":"Chin Med J"},{"issue":"2","key":"10052_CR18","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.jvir.2017.07.026","volume":"29","author":"NE Frenk","year":"2018","unstructured":"Frenk NE, Daye D, Tuncali K et al (2018) Local control and survival after image-guided percutaneous ablation of adrenal metastases. J Vasc Interv Radiol 29(2):276\u2013284","journal-title":"J Vasc Interv Radiol"},{"issue":"3","key":"10052_CR19","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/j.radonc.2014.02.002","volume":"110","author":"L Kestin","year":"2014","unstructured":"Kestin L, Grills I, Guckenberger M et al (2014) Dose-response relationship with clinical outcome for lung stereotactic body radiotherapy (SBRT) delivered via online image guidance. Radiother Oncol 110(3):499\u2013504","journal-title":"Radiother Oncol"},{"issue":"2","key":"10052_CR20","doi-asserted-by":"publisher","first-page":"185","DOI":"10.3748\/wjg.v19.i2.185","volume":"19","author":"AK Shadad","year":"2013","unstructured":"Shadad AK, Sullivan FJ, Martin JD, Egan LJ (2013) Gastrointestinal radiation injury: symptoms, risk factors and mechanisms. World J Gastroenterol 19(2):185\u2013198","journal-title":"World J Gastroenterol"},{"issue":"5","key":"10052_CR21","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1016\/j.ijrobp.2016.12.024","volume":"97","author":"DA Hamstra","year":"2017","unstructured":"Hamstra DA, Mariados N, Sylvester J et al (2017) Continued benefit to rectal separation for prostate radiation therapy: final results of a phase III trial. Int J Radiat Oncol Biol Phys 97(5):976\u2013985","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"3","key":"10052_CR22","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1016\/j.ijrobp.2018.02.024","volume":"101","author":"AD Rao","year":"2018","unstructured":"Rao AD, Shin EJ, Beck SE et al (2018) Demonstration of safety and feasibility of hydrogel marking of the pancreas-duodenum interface for Image Guided Radiation Therapy (IGRT) in a porcine model: implications in IGRT for pancreatic cancer patients. Int J Radiat Oncol Biol Phys 101(3):640\u2013645","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"10052_CR23","doi-asserted-by":"publisher","first-page":"E242","DOI":"10.1016\/j.ijrobp.2019.06.1923","volume":"105","author":"AD Rao","year":"2019","unstructured":"Rao AD, Shin EJ, Meyer JJ et al (2019) Evaluation of a novel absorbable radiopaque hydrogel in patients undergoing Image-Guided Radiotherapy (IGRT) for Borderline resectable and locally advanced pancreatic adenocarcinoma. Int J Radiat Oncol Biol Phys 105(1):E242\u2013E243. https:\/\/doi.org\/10.1016\/j.ijrobp.2019.06.1923","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"10","key":"10052_CR24","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1016\/j.ejso.2016.05.021","volume":"42","author":"HN Ismael","year":"2016","unstructured":"Ismael HN, Denbo J, Cox S et al (2016) Biologic mesh spacer placement facilitates safe delivery of dose-intense radiation therapy: a novel treatment option for unresectable liver tumors. Eur J Surg Oncol 42(10):1591\u20131596","journal-title":"Eur J Surg Oncol"},{"issue":"4","key":"10052_CR25","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1016\/j.adro.2019.05.002","volume":"4","author":"R Sasaki","year":"2019","unstructured":"Sasaki R, Demizu Y, Yamashita T et al (2019) First-in-human phase 1 study of a nonwoven fabric bioabsorbable spacer for particle therapy: Space-Making Particle Therapy (SMPT). Adv Radiat Oncol 4(4):729\u2013737","journal-title":"Adv Radiat Oncol"},{"issue":"5","key":"10052_CR26","doi-asserted-by":"publisher","first-page":"2123","DOI":"10.1002\/cam4.2100","volume":"8","author":"S Rudra","year":"2019","unstructured":"Rudra S, Jiang N, Rosenberg SA et al (2019) Using adaptive magnetic resonance image-guided radiation therapy for treatment of inoperable pancreatic cancer. Cancer Med 8(5):2123\u20132132","journal-title":"Cancer Med"}],"container-title":["Clinical &amp; Experimental Metastasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10585-020-10052-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10585-020-10052-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10585-020-10052-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T23:35:39Z","timestamp":1626910539000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10585-020-10052-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,22]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10052"],"URL":"https:\/\/doi.org\/10.1007\/s10585-020-10052-0","relation":{},"ISSN":["0262-0898","1573-7276"],"issn-type":[{"value":"0262-0898","type":"print"},{"value":"1573-7276","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,22]]},"assertion":[{"value":"27 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest. The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Army, Department of Defense, or the U.S. Government.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"IRB approval was obtained by both institutions.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"A waiver of informed consent was obtained from the IRB of both institutions.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}