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In this study, we examine the effect of social determinants of health, those conditions in which people live, among individuals with serious mental illnesses (SMI) who are actively engaged with mental health services. Using a sample of 203 clients at a community mental health clinic, this study (1) explores the prevalence of three social determinants of health: food insecurity, homelessness, and neighborhood disorder, and (2) assesses their associations with five outcomes of health, including mental health (overall mental health and life satisfaction) and physical health (overall physical health, number of chronic health conditions, and perceived daily limits). Our findings demonstrated that food insecurity and neighborhood disorder were prevalent within our sample of people with SMI (64% and 93% respectively), while homelessness was not (7%). Furthermore, a series of OLS regressions showed food insecurity and neighborhood disorder to be associated with poor mental and physical health, while homelessness was not significantly associated with any outcomes. These findings suggest that individuals with SMI who are actively engaged in treatment have increased risk of food insecurity and poor neighborhood conditions, which in turn may negatively impact their overall health. We suggest that mental health service providers be aware of the influence of social conditions on their patients and that clinics may be uniquely positioned to identify and intervene for individuals at risk of experiences that may be detrimental to their recovery.<\/jats:p>","DOI":"10.1007\/s10597-025-01533-1","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T10:18:16Z","timestamp":1762510696000},"page":"385-394","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Food Insecurity, Neighborhood Disorder, and Homelessness among People with Serious Mental Illness"],"prefix":"10.1007","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-4783-1084","authenticated-orcid":false,"given":"Shiah","family":"Kleinman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey","family":"Barrenger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bailey","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khushbakht","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyler","family":"Chinsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa","family":"Battaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanaiya","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivani","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Abd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3054-1903","authenticated-orcid":false,"given":"Natalie","family":"Bonfine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,7]]},"reference":[{"key":"1533_CR1","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1146\/annurev-clinpsy-080921-074730","volume":"19","author":"DM Anglin","year":"2023","unstructured":"Anglin, D. 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