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Given that alcohol consumption may be driven by or worsen PTSD symptoms, it is critical to consider how threat sensitivity relates to drinking in individuals with probable PTSD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this study, 687 adults with probable PTSD (PTSD Checklist for DSM-5 symptoms\u2009\u2265\u200933; M\n                      <jats:sub>age<\/jats:sub>\n                      =30.01; 80% female) completed a 15-day app-based attention bias modification (ABM) protocol to reduce threat-related biases. Participants were randomized into personalized ABM, non-personalized ABM, or placebo training (days 2\u20137, 9\u201314), and completed dot-probe detection assessments on days 1, 8, and 15. Participants reported alcoholic drinks consumed in the past 24\u00a0h every training day. We examined associations of ABM condition, threat sensitivity (self-reported, avoidance and vigilance reaction time biases), stress (past, anticipated), and PTSD symptoms with alcohol consumption (drink count, heavy drinking) using mixed models.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Personalized ABM was not significantly associated with reduced drink count, relative to placebo (rate ratio\n                      <jats:italic>[RR]<\/jats:italic>\n                      \u2009=\u20090.72, 95% CI 0.51, 1.01). Higher self-reported threat sensitivity was associated with lower next-day drink count (\n                      <jats:italic>RR<\/jats:italic>\n                      \u2009=\u20090.93, 95% CI 0.87, 0.99; marginal after multiple corrections), while there was a non-significant effect between avoidance bias and lower next-day drink count (\n                      <jats:italic>RR<\/jats:italic>\n                      \u2009=\u20090.88, 95% CI 0.76, 1.02). Higher past and anticipated stress were associated with lower next-day drink count (\n                      <jats:italic>RR<\/jats:italic>\n                      \u2009=\u20090.92, 95% CI 0.87, 0.96) and heavy drinking (odds ratio\n                      <jats:italic>[OR]<\/jats:italic>\n                      \u2009=\u20090.91, 95% CI 0.82, 1.00), respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings link threat sensitivity and stress with subsequent lower alcohol consumption, necessitating further research on the intersection of these factors with alcohol use in populations with probable PTSD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10608-026-10751-0","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T05:53:49Z","timestamp":1780120429000},"page":"948-959","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Threat Sensitivity, Stress, and Alcohol Use in Probable PTSD: Findings from a Mobile Attention Bias Modification Trial"],"prefix":"10.1007","volume":"50","author":[{"given":"Audrey","family":"Morrow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikael","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Niles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paige","family":"Tripp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek D.","family":"Satre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua D.","family":"Woolley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aoife","family":"O\u2019Donovan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Nishimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,30]]},"reference":[{"issue":"2","key":"10751_CR1","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1080\/02791072.2017.1397304","volume":"50","author":"AC Alexander","year":"2018","unstructured":"Alexander, A. 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