{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T12:46:47Z","timestamp":1769604407197,"version":"3.49.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1-3","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytotechnology"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1007\/s10616-009-9204-1","type":"journal-article","created":{"date-parts":[[2009,7,25]],"date-time":"2009-07-25T03:18:30Z","timestamp":1248491910000},"page":"23-31","source":"Crossref","is-referenced-by-count":1,"title":["An improved primary culture system of pancreatic duct epithelial cells from Wistar rats"],"prefix":"10.1007","volume":"60","author":[{"given":"Ke-Ling","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue-Lian","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lie","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zong-Guang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang-Yu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing-Jing","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Hui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,7,26]]},"reference":[{"key":"9204_CR1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jss.2006.04.025","volume":"136","author":"T Adachi","year":"2006","unstructured":"Adachi T, Tajima Y, Kuroki T et al (2006) Bile-reflux into the pancreatic ducts is associated with the development of intraductal papillary carcinoma in hamsters. J Surg Res 136:106\u2013111","journal-title":"J Surg Res"},{"key":"9204_CR2","doi-asserted-by":"crossref","first-page":"5659","DOI":"10.1158\/0008-5472.CAN-04-0807","volume":"64","author":"C Agbunag","year":"2004","unstructured":"Agbunag C, Bar-Sagi D (2004) Oncogenic K-ras drives cell cycle progression and phenotypic conversion of primary pancreatic duct epithelial cells. Cancer Res 64:5659\u20135663","journal-title":"Cancer Res"},{"key":"9204_CR3","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0076-6879(05)07055-2","volume":"407","author":"C Agbunag","year":"2005","unstructured":"Agbunag C, Lee KE, Buontempo S et al (2005) Pancreatic duct epithelial isolation and cultivation in two-dimensional and three-dimensional culture systems. Method Enzymol 407:703\u2013710","journal-title":"Method Enzymol"},{"key":"9204_CR4","doi-asserted-by":"crossref","first-page":"7999","DOI":"10.1073\/pnas.97.14.7999","volume":"97","author":"S Bonner-Weir","year":"2000","unstructured":"Bonner-Weir S, Taneja M, Weir GC et al (2000) In vitro cultivation of human islets from expanded ductal tissue. Proc Natl Acad Sci 97:7999\u20138004","journal-title":"Proc Natl Acad Sci"},{"key":"9204_CR5","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1089\/ten.2006.12.939","volume":"12","author":"MI Boretti","year":"2006","unstructured":"Boretti MI, Gooch KJ (2006) Induced cell clustering enhances islet beta cell formation from human cultures enriched for pancreatic ductal epithelial cells. Tissue Eng 12:939\u2013948","journal-title":"Tissue Eng"},{"key":"9204_CR6","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00006676-199810000-00004","volume":"17","author":"CU Cotton","year":"1998","unstructured":"Cotton CU (1998) Ion-transport properties of cultured bovine pancreatic duct epithelial cells. Pancreas 17:247\u2013255","journal-title":"Pancreas"},{"key":"9204_CR7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1089\/scd.2006.0073","volume":"16","author":"JS D\u2019Alessandro","year":"2007","unstructured":"D\u2019Alessandro JS, Lu K, Fung BP et al (2007) Rapid and efficient in vitro generation of pancreatic islet progenitor cells from nonendocrine epithelial cells in the adult human pancreas. Stem Cells Dev 16:75\u201389","journal-title":"Stem Cells Dev"},{"key":"9204_CR8","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF01842701","volume":"8","author":"S Githens","year":"1983","unstructured":"Githens S, Whelan JF (1983) Isolation and culture of hamster pancreatic ducts. J Tissue Cult Methods 8:97\u2013102","journal-title":"J Tissue Cult Methods"},{"key":"9204_CR9","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1002\/1097-0142(19810315)47:6+<1505::AID-CNCR2820471411>3.0.CO;2-J","volume":"47","author":"S Githens","year":"1981","unstructured":"Githens S, Holmquist DR, Whelan JF et al (1981) Morphologic and biochemical characteristics of isolated and cultured pancreatic ducts. Cancer 47:1505\u20131512","journal-title":"Cancer"},{"key":"9204_CR10","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/00006676-198707000-00010","volume":"2","author":"S Githens","year":"1987","unstructured":"Githens S, Finley JJ, Patke CL et al (1987) Biochemical and histochemical characterization of cultured rat and hamster pancreatic ducts. Pancreas 2:427\u2013438","journal-title":"Pancreas"},{"key":"9204_CR11","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.biocel.2004.07.010","volume":"37","author":"A Grapin-Botton","year":"2005","unstructured":"Grapin-Botton A (2005) Ductal cells of the pancreas. Int J Biochem Cell B 37:504\u2013510","journal-title":"Int J Biochem Cell B"},{"key":"9204_CR12","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1097\/00006676-199109000-00003","volume":"6","author":"TG Heimann","year":"1991","unstructured":"Heimann TG, Githens S (1991) Rat pancreatic duct epithelium cultured on a porous support coated with extracelluar matrix. Pancreas 6:514\u2013521","journal-title":"Pancreas"},{"key":"9204_CR13","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/S0002-9440(10)64800-6","volume":"157","author":"OY Hong","year":"2000","unstructured":"Hong OY, Lun-jun M, Catherine L et al (2000) Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype. Am J Pathol 157:1623\u20131631","journal-title":"Am J Pathol"},{"key":"9204_CR14","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1007\/BF02629092","volume":"24","author":"SR Hootman","year":"1988","unstructured":"Hootman SR, Logsdon CD (1988) Isolation and monolayer culture of guinea pig pancreatic duct epithelial cells. In Vitro Cell Dev Biol 24:566\u2013574","journal-title":"In Vitro Cell Dev Biol"},{"key":"9204_CR15","doi-asserted-by":"crossref","first-page":"5045","DOI":"10.1158\/0008-5472.CAN-04-3208","volume":"65","author":"Q Jiaying","year":"2005","unstructured":"Jiaying Q, Jiangong N, Ming L et al (2005) In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis. Cancer Res 65:5045\u20135053","journal-title":"Cancer Res"},{"key":"9204_CR16","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1016\/S0041-1345(96)00705-1","volume":"29","author":"RM Jindal","year":"1997","unstructured":"Jindal RM, McDaniel HM, Filo RS et al (1997) Stem cell potential of pancreatic duct-epithelial cells. Transplant P 29:1502","journal-title":"Transplant P"},{"key":"9204_CR17","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0002-9440(10)65567-8","volume":"153","author":"L Ni","year":"1998","unstructured":"Ni L, Toru F, Masao K et al (1998) Comparative phenotypic studies of duct epithelial cell Lines derived from normal human pancreas and pancreatic carcinoma. Am J Pathol 153:263\u2013269","journal-title":"Am J Pathol"},{"key":"9204_CR18","doi-asserted-by":"crossref","first-page":"929","DOI":"10.3727\/000000006783981431","volume":"15","author":"H Noguchi","year":"2006","unstructured":"Noguchi H, Xu G, Matsumoto S et al (2006) Induction of pancreatic stem\/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology. Cell Transplant 15:929\u2013938","journal-title":"Cell Transplant"},{"key":"9204_CR19","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0303-7207(96)03977-9","volume":"126","author":"C \u00d6berg-Welsh","year":"1997","unstructured":"\u00d6berg-Welsh C, Sandler S, Andersson A et al (1997) Effects of vascular endothelial growth factor on pancreatic duct cell replication and the insulin production of fetal islet-like cell clusters in vitro. Mol Cell Endocrinol 126:125\u2013132","journal-title":"Mol Cell Endocrinol"},{"key":"9204_CR20","first-page":"977","volume":"148","author":"D Oda","year":"1996","unstructured":"Oda D, Savard CE, Nguyen TD et al (1996) Dog pancreatic duct epithelial cells: long-term culture and characterization. Am J Pathol 148:977\u2013985","journal-title":"Am J Pathol"},{"key":"9204_CR21","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/BF02617917","volume":"14","author":"GD Stoner","year":"1978","unstructured":"Stoner GD, Harris CC, Bostwick DG et al (1978) Isolation and characterization of epithelial cells from bovine pancreatic duct. In Vitro 14:581\u2013590","journal-title":"In Vitro"},{"key":"9204_CR22","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/00006676-199303000-00017","volume":"8","author":"B Trautmann","year":"1993","unstructured":"Trautmann B, Schlitt HJ, Hahn EG et al (1993) Isolation, culture, and characterization of human pancreatic duct cells. Pancreas 8:248\u2013254","journal-title":"Pancreas"},{"key":"9204_CR23","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0014-4827(87)90009-7","volume":"168","author":"M-S Tsao","year":"1987","unstructured":"Tsao M-S, Duguid WP (1987) Establishment of propagable epithelial cell lines from normal adult rat pancreas. Exp Cell Res 168:365\u2013375","journal-title":"Exp Cell Res"},{"key":"9204_CR24","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.2337\/db06-1670","volume":"56","author":"S Yatoh","year":"2007","unstructured":"Yatoh S, Dodge R, Akashi T et al (2007) Differentiation of affinity-purified human pancreatic duct cells to beta-cells. Diabetes 56:1802\u20131809","journal-title":"Diabetes"},{"key":"9204_CR25","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1097\/01.mpa.0000160959.21580.41","volume":"30","author":"L Yuan","year":"2005","unstructured":"Yuan L, Zong-Guang Z, Qing-Jie X et al (2005) Toll-like receptor 4 detected in exocrine pancreas and the change of expression in cerulein-induced pancreatitis. Pancreas 30:375\u2013381","journal-title":"Pancreas"}],"container-title":["Cytotechnology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10616-009-9204-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10616-009-9204-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10616-009-9204-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T15:29:17Z","timestamp":1559230157000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10616-009-9204-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":25,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["9204"],"URL":"https:\/\/doi.org\/10.1007\/s10616-009-9204-1","relation":{},"ISSN":["0920-9069","1573-0778"],"issn-type":[{"value":"0920-9069","type":"print"},{"value":"1573-0778","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7]]}}}