{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:48:54Z","timestamp":1789534134045,"version":"build-2803163510"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytotechnology"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1007\/s10616-013-9668-x","type":"journal-article","created":{"date-parts":[[2013,11,30]],"date-time":"2013-11-30T05:55:19Z","timestamp":1385790919000},"page":"135-143","source":"Crossref","is-referenced-by-count":25,"title":["Antimicrobial and antioxidant activities with acute toxicity, cytotoxicity and mutagenicity of Cystoseira compressa (Esper) Gerloff & Nizamuddin from the coast of Urla (Izmir, Turkey)"],"prefix":"10.1007","volume":"67","author":[{"given":"Adem","family":"G\u00fcner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c7inel","family":"K\u00f6ksal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015e\u00fcra Baykan","family":"Erel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00fcsniye","family":"Kayalar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe","family":"Nalbantsoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atakan","family":"Sukatar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. \u00dclk\u00fc","family":"Karabay Yava\u015fo\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,12,1]]},"reference":[{"key":"9668_CR1","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S0367-326X(99)00088-X","volume":"70","author":"A Abourriche","year":"1999","unstructured":"Abourriche A, Charrouf M, Berrada M, Bennamara A, Chaib N, Francisco C (1999) Antimicrobial activities and cytotoxicity of the brown algae Cystoseira tamariscifolia. Fitoterapia 70:611\u2013614","journal-title":"Fitoterapia"},{"key":"9668_CR2","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/0031-9422(95)00199-H","volume":"39","author":"V Amico","year":"1995","unstructured":"Amico V (1995) Marine brown algae family Cystoseiraceae: chemistry and taxonomy. Phytochemistry 39:1257\u20131279","journal-title":"Phytochemistry"},{"key":"9668_CR3","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1016\/S0031-9422(00)83896-0","volume":"26","author":"V Amico","year":"1987","unstructured":"Amico V, Neri P, Piattelli M, Ruberto G (1987) Geranylgeraniol-derived diterpenes from the brown alga Bifurcaria Bifurcata: comparison with two other Cystoseiraceae species. Phytochemistry 26:2637\u20132639","journal-title":"Phytochemistry"},{"key":"9668_CR4","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/0031-9422(88)80187-0","volume":"27","author":"V Amico","year":"1988","unstructured":"Amico V, Cunsolo F, Neri P, Piatelli M, Ruberto G (1988) Antimicrobial tetraprenyl toluquinol derivatives from Cystoseira spinosa var. squarrosa. Phytochemistry 27:1327\u20131331","journal-title":"Phytochemistry"},{"key":"9668_CR5","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S1387-2656(00)06024-5","volume":"6","author":"E Armstrong","year":"2000","unstructured":"Armstrong E, Boyd KG, Burgess JG (2000) Prevention of marine biofouling using natural compounds from marine organisms. Biotechnol Annu Rev 6:221\u2013241","journal-title":"Biotechnol Annu Rev"},{"key":"9668_CR6","first-page":"119","volume":"15","author":"P Arumagam","year":"2006","unstructured":"Arumagam P, Ramamurthy P, Santhiya ST, Ramesh A (2006) Antioxidant activity measured in different solvent fractions obtained from Mentha spicata Linn.: an analysis by ABTS+ decolorization assay. Asia Pac J Clin Nutr 15:119\u2013124","journal-title":"Asia Pac J Clin Nutr"},{"key":"9668_CR7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1515\/znc-2003-1-205","volume":"58","author":"SN Ayyad","year":"2003","unstructured":"Ayyad SN, Abdel-Halim OB, Shier WT, Hoye TR (2003) Cytotoxic hydroazulen diterpenes from the brown alga Cystoseira myrica. Z Natureforsch 58:33\u201338","journal-title":"Z Natureforsch"},{"key":"9668_CR8","first-page":"481","volume":"35","author":"E Ballesteros","year":"1992","unstructured":"Ballesteros E, Martin D, Uriz MJ (1992) Biological activity of extracts from some Mediterranean macrophytes. Bot Mar 35:481\u2013485","journal-title":"Bot Mar"},{"key":"9668_CR9","volume-title":"Principles of toxicology testing","author":"FA Barile","year":"2008","unstructured":"Barile FA (2008) Principles of toxicology testing. CRC Press, New York"},{"key":"9668_CR10","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0031-9422(99)00040-0","volume":"52","author":"A Bennamara","year":"1999","unstructured":"Bennamara A, Abourriche A, Berrada M, Charrouf M, Chaib N, Boudouma M, Garneau FX (1999) Methoxybifurcarenone: an antifungal and antibacterial meroditerpenoid from the brown alga Cystoseira tamariscifolia. Phytochemistry 52:37\u201340","journal-title":"Phytochemistry"},{"key":"9668_CR11","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s10126-001-0087-1","volume":"4","author":"SH Bhosale","year":"2002","unstructured":"Bhosale SH, Nagle VL, Jagtap TG (2002) Antifouling potential of some marine organisms from India species of Bacillus and Pseudomonas. Mar Biotechnol 4:111\u2013118","journal-title":"Mar Biotechnol"},{"key":"9668_CR12","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1515\/botm.1985.28.11.505","volume":"28","author":"S Caccamese","year":"1985","unstructured":"Caccamese S, Toscano RM, Furnari G, Cormaci M (1985) Antimicrobial activities of red and brown algae from Southern Italy coast. Bot Mar 28:505\u2013507","journal-title":"Bot Mar"},{"key":"9668_CR13","first-page":"178","volume":"10","author":"CC Chang","year":"2002","unstructured":"Chang CC, Yang MH, Wen HM, Chern JC (2002) Estimation of total flavonoid content in propolis by two complementary colorimetric methods. J Food Drug Anal 10:178\u2013182","journal-title":"J Food Drug Anal"},{"key":"9668_CR14","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1016\/j.phytochem.2004.03.014","volume":"65","author":"G Culioli","year":"2004","unstructured":"Culioli G, Ortalo-Magne A, Daoudi M, Thomas-Guuyon H, Valls R, Piovetti L (2004) Trihydroxylated linear diterpenes from the brown alga Bifurcaria bifurcate. Phytochem 65:2063\u20132069","journal-title":"Phytochem"},{"key":"9668_CR15","volume-title":"CRC handbook of toxicology","year":"1995","unstructured":"Derelanko MJ, Hollinger MA (eds) (1995) CRC handbook of toxicology, 2nd edn. CRC Press, Boca Raton, FL","edition":"2"},{"key":"9668_CR16","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jembe.2004.03.010","volume":"309","author":"R Ely","year":"2004","unstructured":"Ely R, Supriya T, Naik CG (2004) Antimicrobial activity of marine organisms collected off the coast of South East India. J Exp Biol Ecol 309:121\u2013127","journal-title":"J Exp Biol Ecol"},{"key":"9668_CR17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1039\/np9860300001","volume":"3","author":"DJ Faulkner","year":"1986","unstructured":"Faulkner DJ (1986) Marine natural products. Nat Prod Rep 3:1\u201333","journal-title":"Nat Prod Rep"},{"key":"9668_CR18","first-page":"1671","volume":"93","author":"DJ Faulkner","year":"1993","unstructured":"Faulkner DJ (1993) Marine natural products chemistry: introduction. Chem Rev 93:1671\u20131673","journal-title":"Chem Rev"},{"key":"9668_CR19","first-page":"181","volume":"34","author":"CI Febles","year":"1995","unstructured":"Febles CI, Arias A, Gil-Rodriguez MC, Hardisson A, Sierra Lopez A (1995) In vitro study of antimicrobial activity in algae (Chlorophyta, Phaeophyta and Rhodophyta) collected from the coast of Tenerife (in Spanish). Anuario del Instituto de Estudios Canarios 34:181\u2013192","journal-title":"Anuario del Instituto de Estudios Canarios"},{"key":"9668_CR20","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/BF00027651","volume":"116","author":"W Fenical","year":"1984","unstructured":"Fenical W, Paul VJ (1984) Antimicrobial and cytotoxic terpenoids from tropical green algae of the family Udoteaceae. Hydrobiologia 116:135\u2013140","journal-title":"Hydrobiologia"},{"key":"9668_CR21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s101230100006","volume":"4","author":"A Gonzalez del Val","year":"2001","unstructured":"Gonzalez del Val A, Platas G, Basilio A (2001) Screening of antimicrobial activities in red, green and brown macroalgae from Gran Canaria (Canary Islands, Spain). Int Microbiol 4:35\u201340","journal-title":"Int Microbiol"},{"key":"9668_CR22","first-page":"219","volume":"13","author":"HI Heiba","year":"1993","unstructured":"Heiba HI, Al-Nagdy SA, Rizk AM, Durgham MM (1993) The aminoacid composition of some common marine algae from Qatar (Arabian Gulf). Qatar Uni Sci I 13:219\u2013225","journal-title":"Qatar Uni Sci I"},{"key":"9668_CR23","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1515\/botm.1984.27.8.387","volume":"27","author":"LM Hodgson","year":"1984","unstructured":"Hodgson LM (1984) Antimicrobial and antineoplastic activity in some South Florida seaweeds. Bot Mar 27:387\u2013390","journal-title":"Bot Mar"},{"key":"9668_CR24","doi-asserted-by":"crossref","first-page":"6117","DOI":"10.1021\/jf050463u","volume":"53","author":"HF Hsu","year":"2005","unstructured":"Hsu HF, Houng JY, Chang CL, Wu CC, Chang FR, Wu YC (2005) Antioxidant activity, cytotoxicity, and DNA information of Glossogyne tenuifolia. J Agric Food Chem 53:6117\u20136125","journal-title":"J Agric Food Chem"},{"key":"9668_CR25","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1021\/jf030723c","volume":"53","author":"D Huang","year":"2005","unstructured":"Huang D, Ou B, Prior L (2005) The chemistry behind antioxidant capacity assays. J Agric Food Chem 53:1841\u20131856","journal-title":"J Agric Food Chem"},{"key":"9668_CR26","first-page":"22","volume":"17","author":"E Huve","year":"1972","unstructured":"Huve E (1972) Aper\u00e7u sur la distribution en mer \u00c9g\u00e9e de quelques esp\u00e8ces du genre Cystoseira (Pheophycees, Fucales). Soc Phycol de France 17:22\u201337","journal-title":"Soc Phycol de France"},{"key":"9668_CR27","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.jep.2012.05.046","volume":"142","author":"L Liu","year":"2012","unstructured":"Liu L, Heinrich M, Myers S, Dworjanyn SA (2012) Towards a better understanding of medicinal uses of the brown seaweed Sargassum in Traditional Chinese Medicine: a phytochemical and pharmacological review. J Ethnopharmacol 142:591\u2013619","journal-title":"J Ethnopharmacol"},{"key":"9668_CR28","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0165-1161(83)90010-9","volume":"113","author":"DM Maron","year":"1983","unstructured":"Maron DM, Ames BN (1983) Revised methods for the Salmonella mutagenicity test. Mutat Res 113:173\u2013215","journal-title":"Mutat Res"},{"key":"9668_CR29","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1017\/S0025315404009567h","volume":"84","author":"R Mart\u00ed","year":"2004","unstructured":"Mart\u00ed R, Uriz MJ, Ballesteros E, Turon X (2004) Benthic assemblages in two Mediterranean caves: species diversity and coverage as a function of abiotic parameters and geographic distance. J Mar Biol Assoc UK 84:557\u2013572","journal-title":"J Mar Biol Assoc UK"},{"key":"9668_CR30","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.foodchem.2004.10.006","volume":"91","author":"A Meda","year":"2005","unstructured":"Meda A, Lamien CE, Romito M, Millogo J, Nacoulma OG (2005) Determination of the total phenolic, flavonoid and praline contents in Burkina Fasan honey, as well as their radical scavenging activity. Food Chem 91:571\u2013577","journal-title":"Food Chem"},{"key":"9668_CR31","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.tifs.2011.09.001","volume":"23","author":"S Mohamed","year":"2012","unstructured":"Mohamed S, Hashim SN, Rahman HA (2012) Seaweeds: a sustainable functional food for complementary and alternative therapy. Trends Food Sci Tech 23:83\u201396","journal-title":"Trends Food Sci Tech"},{"key":"9668_CR32","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","volume":"65","author":"T Mossman","year":"1983","unstructured":"Mossman T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immun Meth 65:55\u201363","journal-title":"J Immun Meth"},{"key":"9668_CR33","volume-title":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard. NCCLS document M7-A6","author":"NCCLS, National Committee for Clinical Laboratory Standards","year":"2003","unstructured":"NCCLS, National Committee for Clinical Laboratory Standards (2003) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard. NCCLS document M7-A6, 8th edn. NCCLS, Wayne, PA","edition":"8"},{"key":"9668_CR34","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1021\/jf970470l","volume":"46","author":"Y Okada","year":"1998","unstructured":"Okada Y, Okada M (1998) Scavenging effect of water soluble proteins in broad beans on free radicals and active oxygen species. J Agric Food Chem 46:401\u2013406","journal-title":"J Agric Food Chem"},{"key":"9668_CR35","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/13880200600685949","volume":"44","author":"G Ozdemir","year":"2006","unstructured":"Ozdemir G, Horzum Z, Sukatar A, Karabay-Yavasoglu NU (2006) Antimicrobial activities of volatile components and various extracts of Dictyopteris membranaceae and Cystoseira barbata from the coast of Izmir, Turkey. Pharm Biol 44:183\u2013188","journal-title":"Pharm Biol"},{"key":"9668_CR36","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1006\/abio.1999.4019","volume":"269","author":"P Prieto","year":"1999","unstructured":"Prieto P, Pineda M, Aguilar M (1999) Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E. Anal Biochem 269:337\u2013341","journal-title":"Anal Biochem"},{"key":"9668_CR37","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0891-5849(98)00315-3","volume":"26","author":"R Re","year":"1999","unstructured":"Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biol Med 26:1231\u20131237","journal-title":"Free Radical Biol Med"},{"key":"9668_CR38","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/BF00027657","volume":"116","author":"JL Reichelt","year":"1984","unstructured":"Reichelt JL, Borowitzka MA (1984) Antimicrobial activity from marine algae: results of a large-scale screening program. Hydrobiologia 116:158\u2013167","journal-title":"Hydrobiologia"},{"key":"9668_CR39","first-page":"391","volume":"14","author":"AM Safer","year":"1999","unstructured":"Safer AM, al-Nughamish AJ (1999) Hepatotoxicity induced by the antioxidant food additive, butylated hydroxytoluene (BHT), in rats: an electron microscopical study. Histol Histopathol 14:391\u2013406","journal-title":"Histol Histopathol"},{"key":"9668_CR40","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3989\/scimar.2007.71n1101","volume":"71","author":"N Salvador","year":"2007","unstructured":"Salvador N, G\u00f3mez-Garreta A, Lavelli L, Ribera MA (2007) Antimicrobial activity of Iberian macroalgae. Sci Mar 71:101\u2013113","journal-title":"Sci Mar"},{"key":"9668_CR41","first-page":"357","volume":"37","author":"VMVS Sastry","year":"1994","unstructured":"Sastry VMVS, Rao GRK (1994) Antibacterial substances from marine algae: successive extraction using benzene, chloroform and methanol. Bot Mar 37:357\u2013360","journal-title":"Bot Mar"},{"key":"9668_CR42","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1126\/science.2183350","volume":"248","author":"PJ Scheuer","year":"1990","unstructured":"Scheuer PJ (1990) Some marine ecological phenomena: chemical basis and biomedical potential. Science 248:173\u2013177","journal-title":"Science"},{"key":"9668_CR43","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1021\/jf0352778","volume":"52","author":"NP Seeram","year":"2004","unstructured":"Seeram NP, Adams LS, Hardy ML, Heber D (2004) Total cranberry extract versus its phytochemical constituents: antiproliferative and synergistic effects against human tumor cell lines. J Agric Food Chem 52:2512\u20132517","journal-title":"J Agric Food Chem"},{"key":"9668_CR44","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1142\/S0192415X04001722","volume":"32","author":"ZH Shao","year":"2004","unstructured":"Shao ZH, Vanden Hoek TL, Li CQ, Schumacker PT, Becker LB, Chan KC, Qin Y, Yin JJ, Yuan CS (2004) Synergistic effect of Scutellaria baicalensis and grape seed proanthocyanidins on scavenging reactive oxygen species in vitro. Am J Chin Med 32:89\u201395","journal-title":"Am J Chin Med"},{"key":"9668_CR45","volume-title":"Statistical methods","author":"GW Snedecor","year":"1968","unstructured":"Snedecor GW, Cochran WG (1968) Statistical methods. Oxford and IBD Publishing Co., Calcutta"},{"key":"9668_CR46","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/tox.20119","volume":"20","author":"A Surakka","year":"2005","unstructured":"Surakka A, Sihvonen LM, Lehtim\u00e4ki JM, Wahlsten M, Vuorela P, Sivonen K (2005) Benthic cyanobacteria from the Baltic Sea contain cytotoxic Anabaena, Nodularia and Nostoc strains and an apoptosis inducing Phormidium strain. Environ Toxicol 20:285\u2013292","journal-title":"Environ Toxicol"},{"key":"9668_CR47","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1021\/np0204038","volume":"66","author":"S Takamatsu","year":"2003","unstructured":"Takamatsu S, Hodges TW, Rajbhandari I, Gerwick WH, Hamann MT, Nagle DG (2003) Marine natural products as novel antioxidant prototypes. J Nat Prod 66:605\u2013608","journal-title":"J Nat Prod"},{"key":"9668_CR48","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1515\/bot.2010.044","volume":"53","author":"MS Tierney","year":"2010","unstructured":"Tierney, Croft AK, Hayes M (2010) A review of antihypertensive and antioxidant activities in macroalgae. Bot Mar 53:387\u2013408","journal-title":"Bot Mar"},{"key":"9668_CR49","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0031-9422(94)00849-O","volume":"39","author":"R Valls","year":"1995","unstructured":"Valls R, Piovetti L, Banaigs B, Archavlis A, Pellegrini M (1995) (S)-13-Hydroxygeranylgeraniol-derived furanoditerpenes from Bifurcaria bifurcata. Phytochemistry 39:145\u2013149","journal-title":"Phytochemistry"},{"key":"9668_CR50","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/1475-2891-10-83","volume":"10","author":"K Wada","year":"2011","unstructured":"Wada K, Nakamura K, Tamai Y, Tsuji M, Sahashi Y, Watanabe K, Ohtsuchi S, Yamamoto K, Ando K, Nagata C (2011) Seaweed intake and blood pressure levels in healthy pre-school Japanese children. Nutr J 10:83","journal-title":"Nutr J"},{"key":"9668_CR51","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0304-3959(83)90201-4","volume":"16","author":"M Zimmermann","year":"1983","unstructured":"Zimmermann M (1983) Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16:109\u2013110","journal-title":"Pain"},{"key":"9668_CR52","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s10811-006-9152-5","volume":"19","author":"M Zubia","year":"2007","unstructured":"Zubia M, Robledo D, Freile-Pelegrin Y (2007) Antioxidant activities in tropical marine macroalgae from the Yucatan Peninsula, Mexico. J Appl Phycol 19:449\u2013458","journal-title":"J Appl Phycol"}],"container-title":["Cytotechnology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10616-013-9668-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10616-013-9668-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10616-013-9668-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T14:53:52Z","timestamp":1688828032000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10616-013-9668-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,1]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["9668"],"URL":"https:\/\/doi.org\/10.1007\/s10616-013-9668-x","relation":{},"ISSN":["0920-9069","1573-0778"],"issn-type":[{"value":"0920-9069","type":"print"},{"value":"1573-0778","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,1]]}}}