{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T16:41:34Z","timestamp":1773074494016,"version":"3.50.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1007\/s10620-005-2651-4","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T15:40:17Z","timestamp":1114616417000},"page":"847-852","source":"Crossref","is-referenced-by-count":42,"title":["Prevalence of Helicobacter pylori Infection in Male Patients with Osteoporosis and Controls"],"prefix":"10.1007","volume":"50","author":[{"given":"N.","family":"Figura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Gennari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Merlotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Lenzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Campagna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Franci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Lucani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Trabalzini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Bianciardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Gonnelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Santucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Nut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1210\/endo.139.6.6087","volume":"139","author":"R Pacifici","year":"1998","unstructured":"Pacifici R: Cytokines, estrogen, and postmenopausal osteoporosis\u2013The second decade. Endocrinology 139:2659\u20132661, 1998","journal-title":"Endocrinology"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1210\/jcem.87.4.8417","volume":"87","author":"S Khosla","year":"2002","unstructured":"Khosla S, Melton LJ 3rd, Riggs BL: Clinical review 144: Estrogen and the male skeleton. J Clin Endocrinol Metab 87:1443\u20131450, 2002","journal-title":"J Clin Endocrinol Metab"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"14648","DOI":"10.1073\/pnas.93.25.14648","volume":"93","author":"S Censini","year":"1996","unstructured":"Censini S, Lange C, Xiang Z, Crabtree JE, Ghiara P, Borodovsky M, Rappuoli R, Covacci A: cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci USA 93:14648\u201314653, 1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR4","first-page":"290","volume":"31","author":"F Perri","year":"1999","unstructured":"Perri F, Clemante R, Festa V, Checchia De Ambrosio C, Quitadamo M, Fusillo M, Grossi E, Andriuli A: Serum tumour necrosis factor-alfa is increased in patients with Helicobacter pylori infection and CagA antibodies. Ital J Gastroenterol Hepatol 31:290\u2013294, 1999","journal-title":"Ital J Gastroenterol Hepatol"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S1590-8658(01)80711-8","volume":"33","author":"M Kowalski","year":"2001","unstructured":"Kowalski M, Konturek PC, Pieniazek P, Karczewska E, Kluczka A, Grove R, Kranig W, Nasseri R, Thale J, Hahn EG, Konturek SJ: Prevalence of Helicobacter pylori infection in coronary artery disease and effect of its eradication on coronary lumen reduction after percutaneous coronary angioplasty. Digest Liver Dis 33:222\u2013229, 2001","journal-title":"Digest Liver Dis"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650090802","volume":"9","author":"JA Kanis","year":"1994","unstructured":"Kanis JA, Melton LJ, Christiansen C, Johnston CC, Khaltaev N: The diagnosis of osteoporosis. J Bone Miner Res 9:1137\u20131141, 1994","journal-title":"J Bone Miner Res"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1046\/j.1523-5378.1998.08018.x","volume":"3","author":"DY Graham","year":"1998","unstructured":"Graham DY, Osato MS, Olson CA, Zhang J, Figura N: Effect of H. pylori infection and CagA status on leukocyte counts and liver function tests: Extra-gastric manifestation of H. pylori infection. Helicobacter 3:174\u2013178, 1998","journal-title":"Helicobacter"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1128\/IAI.63.1.94-98.1995","volume":"63","author":"Z Xiang","year":"1995","unstructured":"Xiang Z, Censini S, Bayeli PF, Telford JL, Figura N, Rappuoli R, Covacci A: Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that the clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating toxin. Infect Immun 63:94\u201398, 1995","journal-title":"Infect Immun"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1136\/hrt.78.3.273","volume":"78","author":"MA Mendall","year":"1997","unstructured":"Mendall MA, Patel P, Asante M, Ballam L, Morris J, Strachan DP, Camm AJ, Northfield TC: Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease. Heart 78:273\u2013277, 1997","journal-title":"Heart"},{"key":"CR10","first-page":"49","volume":"163","author":"IW Fong","year":"2000","unstructured":"Fong IW: Emerging relations between infectious diseases and coronary artery. CMAJ 163:49\u201356, 2000","journal-title":"CMAJ"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/j.1749-6632.1989.tb23998.x","volume":"557","author":"J Gauldie","year":"1989","unstructured":"Gauldie J, Richards C, Northemann W, Fey G, Baumann H: IFNB2\/BSF2\/IL-6 is the monocute-derivered HSF that regulates receptor-specific acute phase gene regulation in hepatocytes. Ann NY Acad Sci 557:46\u201359, 1989","journal-title":"Ann NY Acad Sci"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"11312","DOI":"10.1073\/pnas.90.23.11312","volume":"90","author":"N Harada","year":"1993","unstructured":"Harada N, Utsumi T, Takagi Y. Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis. Proc Natl Acad Sci USA. 90:11312\u201311316, 1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR13","first-page":"133","volume":"61","author":"SE Bulun","year":"1997","unstructured":"Bulun SE, Noble LS, Takayama K, Michael MD, Agarwal V, Fisher C, Zhao Y, Hinshelwood MM, Ito Y, Simpson ER: Endocrine disorders associated with inappropriately high aromatase expression J Steroid Biochem Mol Biol 61:133\u2013139, 1997","journal-title":"Endocrine disorders associated with inappropriately high aromatase expression J Steroid Biochem Mol Biol"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1046\/j.1365-2036.2001.01117.x","volume":"15","author":"E Giannini","year":"2001","unstructured":"Giannini E, Fasoli A, Borro P, Chiarbonello B, Malfatti F, Romagnoli P, Botta F, Testa E, Fumagalli A, Polegato S, Savarino V, Testa R: Impairment of cytochrome P-450-dependent liver activity in cirrhotic patients with Helicobacter pylori infection. Alim Pharmacol Ther 15:1967\u20131973, 2001","journal-title":"Alim Pharmacol Ther"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.1210\/endo.143.8.8974","volume":"143","author":"T Ueyama","year":"2002","unstructured":"Ueyama T, Shirasawa N, Numazawa M, Yamada K, Shelangouski M, Ito T, Tsuruo Y: Gastric parietal cells: potent endocrine role in secreting estrogen as a possible regulator of gastro-hepatic axis. Endocrinology 143:3162\u20133170, 2002","journal-title":"Endocrinology"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1572-0241.1998.00375.x","volume":"93","author":"M Sozzi","year":"1998","unstructured":"Sozzi M, Valentini M, Figura N, De Paoli P, Tedeschi R M, Gloghini A, Serraino D, Poletti M, Carbone A: Atrophic gastritis and intestinal metaplasia in Helicobacter pylori infection: the role of CagA status. Am J Gastroenterol 93:375\u2013379, 1998","journal-title":"Am J Gastroenterol"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1136\/gut.50.6.779","volume":"50","author":"The EUROHEPYGAST Study Group","year":"2002","unstructured":"The EUROHEPYGAST Study Group. Risk factors for atrophic chronic gastritis in a European population: results of the Eurohepygast study. Gut 50:779\u2013785, 2002","journal-title":"Gut"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"G309","DOI":"10.1152\/ajpgi.00546.2001","volume":"283","author":"B Neu","year":"2002","unstructured":"Neu B, Randlkofer P, Neuhofer M, Voland P, Mayerhofer A, Gerhard M, Schepp W, Prinz C: Helicobacter pylori induces apoptosis of rat gastric parietal cells. Am J Physiol Gastrointest Liver Physiol 283:G309\u2013G318, 2002","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1136\/gut.41.4.442","volume":"41","author":"Y Yamaoka","year":"1997","unstructured":"Yamaoka Y, Kita M, Kodama T, Sawai N, Kashima K, Imanishi J: Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains. Gut 41:442\u2013511, 1997","journal-title":"Gut"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1023\/A:1005453125433","volume":"45","author":"CQ Li","year":"2000","unstructured":"Li CQ, Pignatelli B, Ohshima H. Coexpression of interleukin-8 and inducible nitric oxide synthase in gastric mucosa infected with cagA+ Helicobacter pylori. Dig Dis Sci 45:55\u201362, 2000","journal-title":"Dig Dis Sci"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1128\/CDLI.7.5.803-809.2000","volume":"7","author":"T Ando","year":"2000","unstructured":"Ando T, Perez-Perez GI, Kusugami K, Ohsuga M, Bloch KC, Blaser MJ: Anti-CagA immunoglobulin G responses correlate with interleukin-8 induction in human gastric mucosal biopsy culture. Clin Diagn Lab Immunol 7:803\u2013809, 2000","journal-title":"Clin Diagn Lab Immunol"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1172\/JCI113125","volume":"80","author":"NA Pocock","year":"1987","unstructured":"Pocock NA, Eisman JA Hopper Jl Yeates MG, Sambrook PN, Eberl S. Genetic determinants of bone mass in adults. A twin study. J Clin Invest 80:706\u2013710, 1987","journal-title":"J Clin Invest"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0378-5122(02)00313-4","volume":"44","author":"H-Y Chen","year":"2002","unstructured":"Chen H-Y, Chen W-C, Wu MC, Tsai F-J, Lin C-C: Interleukin-1\u03b2 and interleukin-1 receptor antagonist gene polymorphism in postmenopausal women: correlation to bone mineral density and susceptibility to osteoporosis. Maturitas 44:49\u201354, 2002","journal-title":"Maturitas"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-005-2651-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-005-2651-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-005-2651-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T03:06:30Z","timestamp":1586228790000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-005-2651-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["2651"],"URL":"https:\/\/doi.org\/10.1007\/s10620-005-2651-4","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,5]]}}}