{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:45:26Z","timestamp":1792640726762,"version":"4.5.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1007\/s10620-006-3198-8","type":"journal-article","created":{"date-parts":[[2006,4,13]],"date-time":"2006-04-13T20:45:15Z","timestamp":1144961115000},"page":"724-731","source":"Crossref","is-referenced-by-count":79,"title":["Preventive Effects of the Probiotic Escherichia coli Strain Nissle 1917 on Acute Secretory Diarrhea in a Pig Model of Intestinal Infection"],"prefix":"10.1007","volume":"51","author":[{"given":"B.","family":"Schroeder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Duncker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Barth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Bauerfeind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. D.","family":"Gruber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Deppenmeier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Breves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"3198_CR1","doi-asserted-by":"crossref","first-page":"361S","DOI":"10.1093\/ajcn\/73.2.361s","volume":"73","author":"J Schrezenmeier","year":"2001","unstructured":"Schrezenmeier J, de Vrese M: Probiotics, prebiotics, and synbiotics\u2014approaching a definition. Am J Clin Nutr 73:361S\u2013364S, 2001","journal-title":"Am J Clin Nutr"},{"key":"3198_CR2","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1046\/j.1440-1746.2000.02162.x","volume":"15","author":"P Gionchetti","year":"2000","unstructured":"Gionchetti P, Rizzello F, Venturi, A, Campieri M: Probiotics in infective diarroea and inflammatory diseases. J Gastroenterol Hepatol 15:489\u2013493, 2000","journal-title":"J Gastroenterol Hepatol"},{"key":"3198_CR3","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1136\/pgmj.2003.008664","volume":"80","author":"HS Gill","year":"2004","unstructured":"Gill HS, Guarner F: Probiotics and human health: a clinical perspective. Postgrad Med J 80:516\u2013526, 2004","journal-title":"Postgrad Med J"},{"key":"3198_CR4","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1097\/00054725-200405000-00018","volume":"10","author":"RN Fedorak","year":"2004","unstructured":"Fedorak RN, Madsen KL: Probiotics and the management of inflammatory bowel disease. Inflamm Bowel Dis 10:286\u2013299, 2004","journal-title":"Inflamm Bowel Dis"},{"key":"3198_CR5","doi-asserted-by":"crossref","first-page":"5432","DOI":"10.1128\/JB.186.16.5432-5441.2004","volume":"186","author":"L Grozdanov","year":"2004","unstructured":"Grozdanov L, Raasch C, Schulze J, Sonnenborn U, Gottschalk G, Hacker J, Dobrindt U: Analysis of the genome structure of the nonpathogenic probiotic Escherichia coli strain Nissle 1917. J Bacteriol 186:5432\u20135441, 2004","journal-title":"J Bacteriol"},{"key":"3198_CR6","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1136\/gut.2003.037747","volume":"53","author":"W Kruis","year":"2004","unstructured":"Kruis W, Fric P, Pokrotnieks J, Lukas M, Fixa B, Kascak M, Kamm MA, Weismueller J, Beglinger C, Stolte M, Wolff C, Schulze J: Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine. Gut 53:1617\u20131623, 2004","journal-title":"Gut"},{"key":"3198_CR7","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0140-6736(98)06343-0","volume":"354","author":"BJ Rembacken","year":"1999","unstructured":"Rembacken BJ, Snelling AM, Hawkey PM, Chalmers DM, Axon AT: Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial. Lancet 354:635\u2013639, 1999","journal-title":"Lancet"},{"key":"3198_CR8","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1128\/AEM.66.6.2578-2588.2000","volume":"66","author":"GW Tannock","year":"2000","unstructured":"Tannock GW, Munro K, Harmsen HJ, Welling GW, Smart J, Gopal PK: Analysis of the fecal microflora of human subjects consuming a probiotic product containing Lactobacillus rhamnosusDR20. Appl Environ Microbiol 66:2578\u20132588, 2000","journal-title":"Appl Environ Microbiol"},{"key":"3198_CR9","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.femsim.2004.04.001","volume":"42","author":"ML Cross","year":"2004","unstructured":"Cross ML, Ganner A, Teilab D, Fray LM: Patterns of cytokine induction by gram-positive and gram-negative probiotic bacteria. FEMS Immunol Med Microbiol 42:173\u2013180, 2004","journal-title":"FEMS Immunol Med Microbiol"},{"key":"3198_CR10","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1128\/CDLI.11.2.372-378.2004","volume":"11","author":"M Schultz","year":"2004","unstructured":"Schultz M, Strauch UG, Linde HJ, Watzl S, Obermeier F, Gottl C, Dunger N, Grunwald N, Sch\u00f6lmerich J, Rath HC: Preventive effects of Escherichia coli strain Nissle 1917 on acute and chronic intestinal inflammation in two different murine models of colitis. Clin Diagn Lab Immunol 11:372\u2013378, 2004","journal-title":"Clin Diagn Lab Immunol"},{"key":"3198_CR11","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1017\/S0022029903006034","volume":"70","author":"M Schultz","year":"2003","unstructured":"Schultz M, Linde HJ, Lehn N, Zimmermann K, Grossmann J, Falk W, Scholmerich J: Immunomodulatory consequences of oral administration of Lactobacillus rhamnosus strain GG in healthy volunteers. J Dairy Res 70:165\u2013173, 2003","journal-title":"J Dairy Res"},{"key":"3198_CR12","doi-asserted-by":"crossref","first-page":"5750","DOI":"10.1128\/IAI.72.10.5750-5758.2004","volume":"72","author":"J Wehkamp","year":"2004","unstructured":"Wehkamp J, Harder J, Wehkamp K, Wehkamp\u2013von Meissner B, Schlee M, Enders C, Sonnenborn U, Nuding S, Bengmark S, Fellermann K, Schroder JM, Stange EF: NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium. Infect Immun 72:5750\u20135758, 2004","journal-title":"Infect Immun"},{"key":"3198_CR13","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0928-8244(03)00368-7","volume":"40","author":"A Altenhoefer","year":"2004","unstructured":"Altenhoefer A, Oswald S, Sonnenborn U, Enders C, Schulze J, Hacker J, Oelschlaeger TA: The probiotic Escherichia coli strain Nissle 1917 interferes with invasion of human intestinal epithelial cells by different enteroinvasive bacterial pathogens. FEMS Immunol Med Microbiol 40:223\u2013229, 2004","journal-title":"FEMS Immunol Med Microbiol"},{"key":"3198_CR14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1046\/j.1365-2036.2003.01638.x","volume":"18","author":"J Boudeau","year":"2003","unstructured":"Boudeau J, Glasser AL, Julien S, Colombel JF, Darfeuille\u2013Michaud A: Inhibitory effect of probiotic Escherichia coli strain Nissle 1917 on adhesion to and invasion of intestinal epithelial cells by adherent\u2013invasive E. coli strains isolated from patients with Crohn\u2019s disease. Aliment Pharmacol Ther 18:45\u201356, 2003","journal-title":"Aliment Pharmacol Ther"},{"key":"3198_CR15","doi-asserted-by":"crossref","first-page":"G613","DOI":"10.1152\/ajpgi.00341.2003","volume":"286","author":"JM Otte","year":"2004","unstructured":"Otte JM, Podolsky DK: Functional modulation of enterocytes by gram-positive and gram-negative microorganisms. Am J Physiol Gastrointest Liver Physiol 286:G613\u2013G626, 2004","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"3198_CR16","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.vascn.2003.12.002","volume":"50","author":"AR Jurjus","year":"2004","unstructured":"Jurjus AR, Khoury NN, Reimund JM: Animal models of inflammatory bowel disease. J Pharmacol Toxicol Methods 50:81\u201392, 2004","journal-title":"J Pharmacol Toxicol Methods"},{"key":"3198_CR17","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1365-2249.2004.02410.x","volume":"136","author":"LA Dieleman","year":"2004","unstructured":"Dieleman LA, Hoentjen F, Qian BF, Sprengers D, Tjwa E, Torres MF, Torrice CD, Sartor RB, Tonkonogy SL: Reduced ratio of protective versus proinflammatory cytokine responses to commensal bacteria in HLA-B27 transgenic rats. Clin Exp Immunol 136:30\u201339, 2004","journal-title":"Clin Exp Immunol"},{"key":"3198_CR18","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00054725-200203000-00001","volume":"8","author":"M Schultz","year":"2002","unstructured":"Schultz M, Veltkamp C, Dieleman LA, Grenther WB, Wyrick PB, Tonkonogy SL, Sartor RB: Lactobacillus plantarum 299V in the treatment and prevention of spontaneous colitis in interleukin-10-deficient mice. Inflamm Bowel Dis 8:71\u201380, 2002","journal-title":"Inflamm Bowel Dis"},{"key":"3198_CR19","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1128\/IAI.20.3.811-815.1978","volume":"20","author":"EE Cahill","year":"1978","unstructured":"Cahill, EE, Glantz PJ: Demonstration of K88ac and K88ab antigens of Escherichia coli by means of immunoelectrophoresis and immunodiffusion. Infect Immun 20:811\u2013815, 1978","journal-title":"Infect Immun"},{"key":"3198_CR20","unstructured":"Anonymous: Amtliche Sammlung von Untersuchungsverfahren nach S 35 LMBG. Untersuchung von Lebensmitteln, Bestimmung der aeroben Keimzahl bei 30\u00b0C in Fleisch und Fleischerzeugnissen. Tropfplatten-Verfahren 1984, L06.0\/0\/9"},{"key":"3198_CR21","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0923-2508(02)00007-4","volume":"154","author":"G Blum-Oehler","year":"2003","unstructured":"Blum-Oehler G, Oswald S, Eiteljorge K: Development of strain-specific PCR reactions for the detection of the probiotic Escherichia coli strain Nissle 1917 in fecal samples. Res Microbiol 154:59\u201366, 2003","journal-title":"Res Microbiol"},{"key":"3198_CR22","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1099\/0022-1317-79-11-2661","volume":"79","author":"TL To","year":"1998","unstructured":"To TL, Ward LA, Yuan L, Saif LJ: Serum and intestinal isotype antibody responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease. J Gen Virol 79:2661\u20132672, 1998","journal-title":"J Gen Virol"},{"key":"3198_CR23","volume-title":"Bergey\u2019s Manual of Determinative Bacteriology, 9th ed","author":"JG Holt","year":"1994","unstructured":"Holt, JG, Krieg NR, Sneath PHA, Staley JT, Williams ST: Bergey\u2019s Manual of Determinative Bacteriology, 9th ed. Baltimore, MD, Lippincott Williams & Wilkins, 1994"},{"key":"3198_CR24","first-page":"75","volume":"73","author":"LH Wieler","year":"2003","unstructured":"Wieler LH, Bauerfeind R: STEC as a veterinary problem. Diagnostics and prophylaxis in animals. Meth Mol Med 73:75\u201389, 2003","journal-title":"Meth Mol Med"},{"key":"3198_CR25","first-page":"38","volume":"105","author":"R Bauerfeind","year":"1992","unstructured":"Bauerfeind R, Wieler LH, Weiss R, Baljer G: Vergleichende Plasmidprofilanalyse von Salmonella typhimuriumvar. Copenhagen-St\u00e0mmen aus einem Salmonellenausbruch bei Klinikpferden. Berl M\u00fcnch Tier\u00e0rztl Wochenschr 105:38\u201342, 1992","journal-title":"Berl M\u00fcnch Tier\u00e0rztl Wochenschr"},{"key":"3198_CR26","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1128\/JCM.31.10.2611-2615.1993","volume":"31","author":"GF Jones","year":"1993","unstructured":"Jones GF, Ward GE, Murtaugh MP, Lin G, Gebhart CJ: Enhanced detection of intracellular organisms of swine proliferative enteritis, ileal symbiont intracellularis, in feces by polymerase chain reaction. J Clin Microbiol 31:2611\u20132615, 1993","journal-title":"J Clin Microbiol"},{"key":"3198_CR27","first-page":"493","volume":"117","author":"W Herbst","year":"2004","unstructured":"Herbst W, Willems H, Baljer G: Verbreitung von Brachyspira hyodysenteriae und Lawsonia intracellularis bei gesunden und durchfallkranken Schweinen. Berl M\u00fcnch Tier\u00e0rztl Wochenschr 117:493\u2013498, 2004","journal-title":"Berl M\u00fcnch Tier\u00e0rztl Wochenschr"},{"key":"3198_CR28","first-page":"317","volume":"93","author":"W Herbst","year":"1986","unstructured":"Herbst W, Lange H, Zsch\u00f6ck M, Krauss H: Nachweis von K\u00e0lberrotavirus mit dem Latextest Rotascreen\u00ae und dem Elektronenmikroskop\u2014eine vergleichende Untersuchung. Dtsch Tier\u00e0rztl Wochenschr 93:317\u2013319, 1986","journal-title":"Dtsch Tier\u00e0rztl Wochenschr"},{"key":"3198_CR29","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1023\/B:DDAS.0000037828.05100.52","volume":"49","author":"B Schr\u00f6der","year":"2004","unstructured":"Schr\u00f6der B, Winckler C, Failing K, Breves G: Studies on the time course of the effects of the probiotic yeast Saccharomyces boulardii on electrolyte transport in pig jejunum. Dig Dis Sci 49:1311\u20131317, 2004","journal-title":"Dig Dis Sci"},{"key":"3198_CR30","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1113\/jphysiol.1991.sp018437","volume":"433","author":"B Schr\u00f6der","year":"1991","unstructured":"Schr\u00f6der B, Kaune R, Harmeyer J: Effects of calcitriol on stimulation of ion transport in pig jejunal mucosa. J Physiol (London) 433:451\u2013465, 1991","journal-title":"J Physiol (London)"},{"key":"3198_CR31","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1085\/jgp.47.3.567","volume":"47","author":"SG Schultz","year":"1964","unstructured":"Schultz SG, Zalusky R: Ion transport in isolated rabbit ileum: I. Short-circuit current and Na fluxes. J Gener Physiol 47:567\u2013584, 1964","journal-title":"J Gener Physiol"},{"key":"3198_CR32","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3168\/jds.S0022-0302(05)72690-4","volume":"88","author":"R Buenau","year":"2005","unstructured":"Buenau R von, Jaekel L, Schubotz E, Schwarz S, Stroff T, Krueger M: Escherichia coli strain Nissle 1917: Significant reduction of neonatal calf diarrhea. J Dairy Sci 88:317\u2013323, 2005","journal-title":"J Dairy Sci"},{"key":"3198_CR33","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1111\/j.1572-0241.2002.05693.x","volume":"97","author":"KM Lammers","year":"2002","unstructured":"Lammers KM, Helwig U, Swennen E, Rizzello F, Venturi A, Caramelli E, Kamm MA, Brigidi P, Gionchetti P, Campieri M: Effect of probiotic strains on interleukin 8 production by HT2\/9\/9A cells. Am J Gastroenterol 97:1182\u20131186, 2002","journal-title":"Am J Gastroenterol"},{"key":"3198_CR34","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0021-9975(85)90039-8","volume":"95","author":"DJ Hampson","year":"1985","unstructured":"Hampson DJ, Hinton M, Kidder DE: Coliform numbers in the stomach and small intestine of healthy pigs following weaning at three weeks of age. J Comp Pathol 95:353\u201362, 1985","journal-title":"J Comp Pathol"},{"key":"3198_CR35","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1365-2672.1985.tb01488.x","volume":"58","author":"M Hinton","year":"1985","unstructured":"Hinton M, Hampson DJ, Hampson E, Linton AH: A comparison of the ecology of Escherichia coli in the intestine of healthy unweaned pigs and pigs after weaning. J Appl Bacteriol 58:471\u2013477, 1985","journal-title":"J Appl Bacteriol"},{"key":"3198_CR36","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0034-5288(93)90026-C","volume":"55","author":"HJ Egberts","year":"1993","unstructured":"Egberts HJ, de Groot EC, van Dijk JE, Vellenga L, Mouwen JM: Tight junctional structure and permeability of porcine jejunum after enterotoxic Escherichia coli infection. Res Vet Sci 55:10\u201314, 1993","journal-title":"Res Vet Sci"},{"key":"3198_CR37","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1046\/j.1439-0396.2000.00277.x","volume":"84","author":"G Breves","year":"2000","unstructured":"Breves G, Walter C, Burmester M, Schr\u00f6der B: In vitro studies on the effects of Saccharomyces boulardii and Bacillus cereus var. toyoi on nutrient transport in pig jejunum. J Anim Physiol Anim Nutr 84:9\u201320, 2000","journal-title":"J Anim Physiol Anim Nutr"},{"key":"3198_CR38","first-page":"R156","volume":"267","author":"HV Carey","year":"1994","unstructured":"Carey HV, Hayden UL, Tucker KE: Fasting alters basal and stimulated ion transport in piglet jejunum. Am J Physiol 267:R156\u2013R163, 1994","journal-title":"Am J Physiol"},{"key":"3198_CR39","first-page":"G1166","volume":"275","author":"R Cermak","year":"1998","unstructured":"Cermak R, Follmer U, Wolffram S: Dietary flavonol quercetin induces chloride secretion in rat colon. Am J Physiol 275:G1166\u2013G1172, 1998","journal-title":"Am J Physiol"},{"key":"3198_CR40","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1076\/apab.104.2.180.12883","volume":"104","author":"B Eto","year":"1996","unstructured":"Eto B, Boisset M, Desjeux JF: Sodium fluoride inhibits the antisecretory effect of peptide YY and its analog in rabbit jejunum. Arch Physiol Biochem 104:180\u2013184, 1996","journal-title":"Arch Physiol Biochem"},{"key":"3198_CR41","first-page":"126","volume":"252","author":"DR Brown","year":"1990","unstructured":"Brown DR, Overend MF, Treder BG: Neurohormonal regulation of ion transport in the porcine distal jejunum. Actions of somatostatin-14 and its natural and synthetic homologs. J Pharmacol Exp Ther 252:126\u2013134, 1990","journal-title":"J Pharmacol Exp Ther"},{"key":"3198_CR42","first-page":"30","volume":"36","author":"C Winckler","year":"1998","unstructured":"Winckler C, Schr\u00f6der B, Breves G: Effects of Saccharomyces boulardii, Bacillus cereus var. caron and Bacillus cereus var. toyoi on epithelial transport functions in pig jejunum. Z Gastroenterol 36 (Suppl 1):30\u201337, 1998","journal-title":"Z Gastroenterol"},{"key":"3198_CR43","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0016-5085(94)94403-2","volume":"106","author":"D Czerucka","year":"1994","unstructured":"Czerucka D, Roux I, Rampal P: Saccharomyces boulardii inhibits secretagogue-mediated adenosine 3\u2032,5\u2032-cyclic monophosphate induction in intestinal cells. Gastroenterol 106:65\u201372, 1994","journal-title":"Gastroenterol"},{"key":"3198_CR44","first-page":"383","volume":"13","author":"D Czerucka","year":"1989","unstructured":"Czerucka D, Nano JL, Bernasconi P, Rampal P: Response to cholera toxin of 2 epithelial intestinal cell lines. Effect of Saccharomyces boulardii. Gastroenterol Clin Biol 13:383\u2013387, 1989","journal-title":"Gastroenterol Clin Biol"},{"key":"3198_CR45","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/00005176-200209000-00021","volume":"35","author":"S Michail","year":"2002","unstructured":"Michail S, Abernathy F: Lactobacillus plantarum reduces the in vitro secretory response of intestinal epithelial cells to enteropathogenic Escherichia coli infection. J Pediatr Gastroenterol Nutr 35:350\u2013355, 2002","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"3198_CR46","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.coph.2003.06.012","volume":"3","author":"JR Thiagarajah","year":"2003","unstructured":"Thiagarajah JR, Verkman AS: CFTR pharmacology and ist role in intestinal fluid secretion. Curr Op Pharmacol 3:594\u2013599, 2003","journal-title":"Curr Op Pharmacol"},{"key":"3198_CR47","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1046\/j.1365-201X.2003.01060.x","volume":"177","author":"B Nilius","year":"2003","unstructured":"Nilius B, Droogmans G: Amazing chloride channels: an overview. Acta Physiol Scan 177:119\u2013147, 2003","journal-title":"Acta Physiol Scan"},{"key":"3198_CR48","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1086\/322799","volume":"184","author":"C Alcantara","year":"2001","unstructured":"Alcantara C, Stenson WF, Steiner TS, Guerrant RL: Role of inducible cyclooxygenase and prostaglandins in Clostridium difficile toxin A-induced secretion and inflammation in an animal model. J Infect Dis 184:648\u2013652, 2001","journal-title":"J Infect Dis"},{"key":"3198_CR49","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1172\/JCI2039","volume":"101","author":"I Castagliuolo","year":"1998","unstructured":"Castagliuolo I, Riegler M, Pasha A, Nikulasson S, Lu B, Gerard C, Gerard NP, Pothoulakis C: Neurokinin-1 (NK-1) receptor is required in Clostridium difficile- induced enteritis. J Clin Invest 101:1547\u20131550, 1998","journal-title":"J Clin Invest"},{"key":"3198_CR50","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1136\/gut.47.suppl_4.iv49","volume":"47","author":"J Santos","year":"2000","unstructured":"Santos J, Perdue MH: Stress and neuroimmune regulation of gut mucosal function. Gut 47 (Suppl 4):49\u201351, 2000","journal-title":"Gut"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-006-3198-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-006-3198-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-006-3198-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T20:32:08Z","timestamp":1586809928000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-006-3198-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":50,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["3198"],"URL":"https:\/\/doi.org\/10.1007\/s10620-006-3198-8","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}