{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T08:27:24Z","timestamp":1782808044305,"version":"3.54.5"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2010,4,21]],"date-time":"2010-04-21T00:00:00Z","timestamp":1271808000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1007\/s10620-010-1223-4","type":"journal-article","created":{"date-parts":[[2010,4,20]],"date-time":"2010-04-20T13:36:53Z","timestamp":1271770613000},"page":"3430-3435","source":"Crossref","is-referenced-by-count":27,"title":["Characteristics and Outcomes of Upper Gastrointestinal Hemorrhage in a Tertiary Referral Hospital"],"prefix":"10.1007","volume":"55","author":[{"given":"Magnus","family":"Halland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael N.","family":"Fitzgerald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerry","family":"Inder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Duggan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Duggan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,4,21]]},"reference":[{"key":"1223_CR1","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.gie.2008.02.040","volume":"67","author":"AN Barkun","year":"2008","unstructured":"Barkun AN. Should every patient with suspected upper GI bleeding receive a proton pump inhibitor while awaiting endoscopy? Gastrointest Endosc. 2008;67:1064\u20131066.","journal-title":"Gastrointest Endosc"},{"key":"1223_CR2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.cgh.2008.08.016","volume":"7","author":"Laine L, McQuaid KR","year":"2009","unstructured":"Laine L, McQuaid KR. Endoscopic therapy for bleeding ulcers: an evidence-based approach based on meta-analyses of randomized controlled trials. Clin Gastroenterol Hepatol. 2009;7:33\u201347.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"1223_CR3","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1046\/j.1365-2036.2001.01013.x","volume":"15","author":"JM Duggan","year":"2001","unstructured":"Duggan JM. Review article: transfusion in gastrointestinal haemorrhage\u2014if, when and how much? Aliment Pharmacol Ther. 2001;15:1109\u20131113.","journal-title":"Aliment Pharmacol Ther"},{"key":"1223_CR4","first-page":"265","volume":"28","author":"PH Jordan Jr","year":"1991","unstructured":"Jordan PH Jr. Surgery for peptic ulcer disease. Curr Probl Surg. 1991;28:265\u2013330.","journal-title":"Curr Probl Surg"},{"key":"1223_CR5","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/S0733-8627(03)00066-X","volume":"21","author":"N Hamoui","year":"2003","unstructured":"Hamoui N, Docherty SD, Crookers PF. Gastrointestinal hemorrhae: is the surgeon obsolete. Emerg Med Clin of NA. 2003;21:1017\u20131056.","journal-title":"Emerg Med Clin of NA"},{"key":"1223_CR6","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1136\/gut.41.5.606","volume":"41","author":"TA Rockall","year":"1997","unstructured":"Rockall TA, Logan RF, Devlin HB, Northfield TC. Influencing the practice and outcome in upper gastrointestinal haemorrhage. Gut. 1997;41:606\u2013611.","journal-title":"Gut"},{"key":"1223_CR7","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.dld.2006.08.002","volume":"38","author":"K Thomopoulos","year":"2006","unstructured":"Thomopoulos K, Theochais G, Mimidis K, et al. Improved survival of patients presenting with acute variceal bleeding. Prognostic indicators of short- and long-term outcome. Dig Liver Dis. 2006;38:899\u2013904.","journal-title":"Dig Liver Dis"},{"key":"1223_CR8","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/01.mcg.0000248004.73075.ad","volume":"42","author":"G Theocharis","year":"2008","unstructured":"Theocharis G, Thomopoulos K, Sakellaropoulos G, et al. Changing trends in the epidemiology and clinical outcome of acute upper gastrointestinal bleeding in a defined geographical area in Greece. J Clin Gastroenterol. 2008;42:128\u2013133.","journal-title":"J Clin Gastroenterol"},{"key":"1223_CR9","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1136\/bmj.315.7107.510","volume":"315","author":"TA Rockall","year":"1997","unstructured":"Rockall TA, Logan RFA, Devlin HB, Blatchford M, Pell J. Acute upper gastrointestinal haemorrhage in west of Scotland: case ascertainment study. BMJ. 1997;315:510\u2013514.","journal-title":"BMJ"},{"key":"1223_CR10","first-page":"1009","volume":"22","author":"NE Tsesmeli","year":"2007","unstructured":"Tsesmeli NE, Kotsaftis PS, Savopoulos CG, Hatzitolios A, et al. Incidence and etiology of acute non-malignant upper gastrointestinal bleeding in northern Greece. Gastroenterology. 2007;22:1009\u20131013.","journal-title":"Gastroenterology"},{"key":"1223_CR11","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1097\/00042737-200506000-00008","volume":"17","author":"FD Fiore","year":"2005","unstructured":"Fiore FD, Lecleire S, Merle V, Herve S, Duhamel C, et al. Changes in characteristics and outcome of acute upper gastrointestinal haemorrhage: a comparison of epidemiology and practices between 1996 and 2000 in a multicentre French study. Eur J Gastroenterol. 2005;17:641\u2013647.","journal-title":"Eur J Gastroenterol"},{"key":"1223_CR12","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/gut.26.5.481","volume":"26","author":"SB Rofe","year":"1985","unstructured":"Rofe SB, Duggan JM, Smith ER, et al. Conservative treatment of gastrointestinal haemorrhage. Gut. 1985;26:481\u2013484.","journal-title":"Gut"},{"key":"1223_CR13","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1136\/gut.10.6.443","volume":"10","author":"BL Chapman","year":"1969","unstructured":"Chapman BL, Duggan JM. Aspirin and uncomplicated peptic ulcer. Gut. 1969;10:443\u2013450.","journal-title":"Gut"},{"key":"1223_CR14","doi-asserted-by":"crossref","first-page":"3011","DOI":"10.1111\/j.1572-0241.2008.02149.x","volume":"103","author":"A Andriulli","year":"2008","unstructured":"Andriulli A, Loperfido S, Focareta R, et al. High- versus low-dose proton pump inhibitors after endoscopic hemostasis in patients with peptic ulcer bleeding: a multicentre, randomized study. Am J Gastroenterol. 2008;103:3011\u20133018.","journal-title":"Am J Gastroenterol"},{"key":"1223_CR15","unstructured":"SAS\/STAT Software Version 9.1 (SAS Institute Inc., Cary, NC, USA)."},{"key":"1223_CR16","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1136\/gut.38.3.316","volume":"38","author":"TA Rockall","year":"1996","unstructured":"Rockall TA, Logan RF, Devlin HB. Risk assessment after acute upper gastrointestinal haemorrhage. Gut. 1996;38:316\u2013321.","journal-title":"Gut"},{"key":"1223_CR17","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1111\/j.1440-1746.2009.05910.x","volume":"24","author":"HF Gidding","year":"2009","unstructured":"Gidding HF, Topp L, Middleton M, et al. The epidemiology of hepatitis C in Australia: notifications, treatment uptake and liver transplantations, 1997\u20132006. J Gastroenterol Hepatol. 2009;24:1648\u20131654.","journal-title":"J Gastroenterol Hepatol"},{"key":"1223_CR18","unstructured":"Alcohol consumption per capita 1996\u20132003. Australian Bureau of Statistics. http:\/\/www.abs.gov.au\/ausstats\/abs@.nsf\/ProductsbyReleaseDate\/E02E0094E2F974AECA25702C00816B50?OpenDocument Accessed March 05, 2010."},{"key":"1223_CR19","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1111\/j.1365-2036.2009.04058.x","volume":"30","author":"J Sadic","year":"2009","unstructured":"Sadic J, Borgstrom A, Manjer J, Toth E, Lindell G. Bleeding peptic ulcer\u2013time trends in incidence, treatment and mortality in Sweden. Aliment Pharmacol Ther. 2009;30:392\u2013398.","journal-title":"Aliment Pharmacol Ther"},{"key":"1223_CR20","first-page":"45","volume":"9","author":"J Parsonnet","year":"1995","unstructured":"Parsonnet J. The incidence of Helicobacter pylori infection. Aliment Pharmacol Ther. 1995;9:45\u201351.","journal-title":"Aliment Pharmacol Ther"},{"key":"1223_CR21","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1046\/j.0306-5251.2001.01190.x","volume":"53","author":"LE Visser","year":"2002","unstructured":"Visser LE, Graatsma HH, Stricker BHC. Contraindicated NSAIDs are frequently prescribed to elderly patients with peptic ulcer disease. Br J Clin Pharmacol. 2002;53:183\u2013188.","journal-title":"Br J Clin Pharmacol"},{"key":"1223_CR22","doi-asserted-by":"crossref","unstructured":"Dorward S, Sreedharan A, Leontiadis GI et al. Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding. Cochrane Database Syst Rev. 2006; Oct 18 (4):CD005415.","DOI":"10.1002\/14651858.CD005415.pub2"},{"key":"1223_CR23","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1002\/bjs.1800731007","volume":"73","author":"SD Blair","year":"1986","unstructured":"Blair SD, Janvrin SB, McCollum CM, Greenhalg RM. Effect of early blood transfusion on gastrointestinal haemorrhage. Br J Surg. 1986;73:783\u2013785.","journal-title":"Br J Surg"},{"key":"1223_CR24","unstructured":"Beecher HK. Resuscitation in men severely wounded in battle. In: De Bakey ME, ed. Surgery in WWII in Vol 11 General Surgery. Washington: Office of the Surgeon General, Dept. of the Army; 1955:3\u201339."},{"key":"1223_CR25","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1056\/NEJM199410273311701","volume":"331","author":"WH Bickell","year":"1994","unstructured":"Bickell WH, Bruttig SP, Millnamow GA, O\u2019Benar J, Wade CE. Immediate versus delayed resuscitation in hypotensive patients with penetrating torso injuries. N Eng J Med. 1994;331:1105\u20131109.","journal-title":"N Eng J Med"},{"key":"1223_CR26","unstructured":"UK comparative audit of upper gastrointestinal bleeding and the use of blood. December 2007. St Elsewhere\u2019s NHS foundation trust. http:\/\/www.bsg.org.uk\/pdf_word_docs\/blood_audit_report_07.pdf . Accessed January 21, 2010."},{"key":"1223_CR27","first-page":"247","volume":"144","author":"JM Duggan","year":"1986","unstructured":"Duggan JM. Haemetemasis patients should be managed in special unit. MJA. 1986;144:247\u2013250.","journal-title":"MJA"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-010-1223-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-010-1223-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-010-1223-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T15:42:57Z","timestamp":1559230977000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-010-1223-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,21]]},"references-count":27,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["1223"],"URL":"https:\/\/doi.org\/10.1007\/s10620-010-1223-4","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,21]]}}}