{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:18:26Z","timestamp":1787800706244,"version":"build-2784847793"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,7,15]],"date-time":"2010-07-15T00:00:00Z","timestamp":1279152000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1007\/s10620-010-1326-y","type":"journal-article","created":{"date-parts":[[2010,7,14]],"date-time":"2010-07-14T20:26:25Z","timestamp":1279139185000},"page":"812-818","source":"Crossref","is-referenced-by-count":25,"title":["Anti-Alpha-Enolase Antibody as a Serologic Marker and Its Correlation with Disease Severity in Intestinal Beh\u00e7et\u2019s Disease"],"prefix":"10.1007","volume":"56","author":[{"given":"Sung Jae","family":"Shin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Chang","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Il","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Kil","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang Hoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,7,15]]},"reference":[{"key":"1326_CR1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0049-0172(98)80001-2","volume":"27","author":"VG Kaklamani","year":"1998","unstructured":"Kaklamani VG, Vaiopoulos G, Kaklamanis PG. Beh\u00e7et\u2019s disease. Semin Arthritis Rheum. 1998;27:197\u2013217.","journal-title":"Semin Arthritis Rheum"},{"key":"1326_CR2","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1056\/NEJM199910213411707","volume":"341","author":"T Sakane","year":"1999","unstructured":"Sakane T, Takeno M, Suzuki N, Inaba G. Beh\u00e7et\u2019s disease. N Engl J Med. 1999;341:1284\u20131291.","journal-title":"N Engl J Med"},{"key":"1326_CR3","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/00002281-200401000-00008","volume":"16","author":"S Yurdakul","year":"2004","unstructured":"Yurdakul S, Hamuryudan V, Yazici H. Beh\u00e7et\u2019s disease. Curr Opin Rheumatol. 2004;16:38\u201342.","journal-title":"Curr Opin Rheumatol"},{"key":"1326_CR4","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S0091-6749(05)80067-3","volume":"86","author":"A Saxon","year":"1990","unstructured":"Saxon A, Shanahan F, Landers C, Ganz T, Targan S. A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease. J Allergy Clin Immunol. 1990;86:202\u2013210.","journal-title":"J Allergy Clin Immunol"},{"key":"1326_CR5","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S0016-5085(98)70252-5","volume":"115","author":"FM Ruemmele","year":"1998","unstructured":"Ruemmele FM, Targan SR, Levy G, Dubinsky M, Braun J, Seidman EG. Diagnostic accuracy of serological assays in pediatric inflammatory bowel disease. Gastroenterology. 1998;115:822\u2013829.","journal-title":"Gastroenterology"},{"key":"1326_CR6","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1111\/j.1572-0241.2001.03613.x","volume":"96","author":"M Peeters","year":"2001","unstructured":"Peeters M, Joossens S, Vermeire S, Vlietinck R, Bossuyt X, Rutgeerts P. Diagnostic value of anti-Saccharomyces cerevisiae and antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease. Am J Gastroenterol. 2001;96:730\u2013734.","journal-title":"Am J Gastroenterol"},{"key":"1326_CR7","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1136\/gut.42.6.788","volume":"42","author":"JF Quinton","year":"1998","unstructured":"Quinton JF, Sendid B, Reumaux D, et al. Anti-Saccharomyces cerevisiae mannan antibodies combined with antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease: prevalence and diagnostic role. Gut. 1998;42:788\u2013791.","journal-title":"Gut"},{"key":"1326_CR8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1128\/CDLI.3.2.219-226.1996","volume":"3","author":"B Sendid","year":"1996","unstructured":"Sendid B, Colombel JF, Jacquinot PM, et al. Specific antibody response to oligomannosidic epitopes in Crohn\u2019s disease. Clin Diagn Lab Immunol. 1996;3:219\u2013226.","journal-title":"Clin Diagn Lab Immunol"},{"key":"1326_CR9","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1177\/096120339400300204","volume":"3","author":"Y Adler","year":"1994","unstructured":"Adler Y, Salozhin K, Tongueze M, Shoenfeld Y, Youinou P. Anti-endothelial cell antibodies: a need for standardization. Lupus. 1994;3:77\u201384.","journal-title":"Lupus"},{"key":"1326_CR10","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1177\/096120339500400203","volume":"4","author":"PL Meroni","year":"1995","unstructured":"Meroni PL, Khamashta MA, Youinou P, Shoenfeld Y. Mosaic of anti-endothelial antibodies. Review of the first international workshop on anti-endothelial antibodies, clinical and pathological significance. Lupus. 1995;4:95\u201399.","journal-title":"Lupus"},{"key":"1326_CR11","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/clin.1993.1059","volume":"67","author":"AO Aydintug","year":"1993","unstructured":"Aydintug AO, Tokgoz G, D\u2019Cruz DP, et al. Antibodies to endothelial cells in patients with Beh\u00e7et\u2019s disease. Clin Immunol Immunopathol. 1993;67:157\u2013162.","journal-title":"Clin Immunol Immunopathol"},{"key":"1326_CR12","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s004030050425","volume":"291","author":"KH Lee","year":"1999","unstructured":"Lee KH, Bang D, Choi ES, Chun WH, Lee ES, Lee S. Presence of circulating antibodies to a disease specific antigen on cultured human dermal microvascular endothelial cells in patients with Beh\u00e7et\u2019s disease. Arch Dermatol Res. 1999;291:374\u2013381.","journal-title":"Arch Dermatol Res"},{"key":"1326_CR13","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1002\/art.11074","volume":"48","author":"KH Lee","year":"2003","unstructured":"Lee KH, Chung HS, Kim HS, et al. Human alpha-enolase from endothelial cells as a target antigen of anti-endothelial cell antibody in Beh\u00e7et\u2019s disease. Arthritis Rheum. 2003;48:2025\u20132035.","journal-title":"Arthritis Rheum"},{"key":"1326_CR14","first-page":"382","volume":"43","author":"Y Mizushima","year":"1988","unstructured":"Mizushima Y, Inaba G, Mimura Y. Diagnostic criteria for Beh\u00e7et\u2019s disease in 1987, and guideline for treating Beh\u00e7et\u2019s disease. Saishin Igaku. 1988;43:382\u2013391. (in Japanese).","journal-title":"Saishin Igaku"},{"key":"1326_CR15","unstructured":"International Study Group for Beh\u00e7et's Disease. Criteria for diagnosis of Beh\u00e7et\u2019s disease. Lancet. 1990;335:1078\u20131080."},{"key":"1326_CR16","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/00054725-200108000-00010","volume":"7","author":"CR Lee","year":"2001","unstructured":"Lee CR, Kim WH, Cho YS, et al. Colonoscopic findings in intestinal Beh\u00e7et\u2019s disease. Inflamm Bowel Dis. 2001;7:243\u2013249.","journal-title":"Inflamm Bowel Dis"},{"key":"1326_CR17","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1148\/radiographics.21.4.g01jl19911","volume":"21","author":"SY Chung","year":"2001","unstructured":"Chung SY, Ha HK, Kim JH, et al. Radiologic findings of Beh\u00e7et\u2019s syndrome involving the gastrointestinal tract. Radiographics. 2001;21:911\u2013924.","journal-title":"Radiographics"},{"key":"1326_CR18","first-page":"109","volume":"27","author":"F Pratesi","year":"2000","unstructured":"Pratesi F, Moscato S, Sabbatini A, Chimenti D, Bombardieri S, Migliorini P. Autoantibodies specific for alpha-enolase in systemic autoimmune disorders. J Rheumatol. 2000;27:109\u2013115.","journal-title":"J Rheumatol"},{"key":"1326_CR19","doi-asserted-by":"crossref","first-page":"14503","DOI":"10.1074\/jbc.273.23.14503","volume":"273","author":"V Pancholi","year":"1998","unstructured":"Pancholi V, Fischetti VA. Alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci. J Biol Chem. 1998;273:14503\u201314515.","journal-title":"J Biol Chem"},{"key":"1326_CR20","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1007\/PL00000910","volume":"58","author":"V Pancholi","year":"2001","unstructured":"Pancholi V. Multifunctional alpha-enolase: its role in diseases. Cell Mol Life Sci. 2001;58:902\u2013920.","journal-title":"Cell Mol Life Sci"},{"key":"1326_CR21","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1086\/317604","volume":"182","author":"PA Fontan","year":"2000","unstructured":"Fontan PA, Pancholi V, Nociari MM, Fischetti VA. Antibodies to streptococcal surface enolase react with human alpha-enolase: implications in poststreptococcal sequelae. J Infect Dis. 2000;182:1712\u20131721.","journal-title":"J Infect Dis"},{"key":"1326_CR22","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/315688a0","volume":"315","author":"H Iida","year":"1985","unstructured":"Iida H, Yahara I. Yeast heat-shock protein of Mr 48,000 is an isoprotein of enolase. Nature. 1985;315:688\u2013690.","journal-title":"Nature"},{"key":"1326_CR23","doi-asserted-by":"crossref","first-page":"138","DOI":"10.2310\/6650.2001.34040","volume":"49","author":"VM Gitlits","year":"2001","unstructured":"Gitlits VM, Toh BH, Sentry JW. Disease association, origin, and clinical relevance of autoantibodies to the glycolytic enzyme enolase. J Investig Med. 2001;49:138\u2013145.","journal-title":"J Investig Med"},{"key":"1326_CR24","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1002\/art.10252","volume":"46","author":"V Saulot","year":"2002","unstructured":"Saulot V, Vittecoq O, Charlionet R, et al. Presence of autoantibodies to the glycolytic enzyme alpha-enolase in sera from patients with early rheumatoid arthritis. Arthritis Rheum. 2002;46:1196\u20131201.","journal-title":"Arthritis Rheum"},{"key":"1326_CR25","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1046\/j.1365-2249.1998.00528.x","volume":"112","author":"C Roozendaal","year":"1998","unstructured":"Roozendaal C, Zhao MH, Horst G, et al. Catalase and alpha-enolase: two novel granulocyte autoantigens in inflammatory bowel disease (IBD). Clin Exp Immunol. 1998;112:10\u201316.","journal-title":"Clin Exp Immunol"},{"key":"1326_CR26","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3349\/ymj.1997.38.6.365","volume":"38","author":"S Lee","year":"1997","unstructured":"Lee S. Diagnostic criteria of Beh\u00e7et\u2019s disease: problems and suggestions. Yonsei Med J. 1997;38:365\u2013369.","journal-title":"Yonsei Med J"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-010-1326-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-010-1326-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-010-1326-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,7]],"date-time":"2020-06-07T00:05:02Z","timestamp":1591488302000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-010-1326-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,15]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["1326"],"URL":"https:\/\/doi.org\/10.1007\/s10620-010-1326-y","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,15]]}}}