{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T13:03:02Z","timestamp":1773666182796,"version":"3.50.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2012,7,8]],"date-time":"2012-07-08T00:00:00Z","timestamp":1341705600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1007\/s10620-012-2297-y","type":"journal-article","created":{"date-parts":[[2012,7,10]],"date-time":"2012-07-10T00:14:31Z","timestamp":1341879271000},"page":"3189-3194","source":"Crossref","is-referenced-by-count":16,"title":["Efficacy of S-Pantoprazole 20\u00a0mg Compared with Pantoprazole 40\u00a0mg in the Treatment of Reflux Esophagitis: A Randomized, Double-Blind Comparative Trial"],"prefix":"10.1007","volume":"57","author":[{"given":"Yu Kyung","family":"Cho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung-Gyu","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Tae","family":"Bak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Poong-Lyul","family":"Rhee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Gyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoon-Yong","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Young","family":"Seol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,7,8]]},"reference":[{"key":"2297_CR1","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/S0889-8553(03)00056-6","volume":"32","author":"LS Welage","year":"2003","unstructured":"Welage LS. Pharmacologic features of proton pump inhibitors and their potential relevance to clinical practice. Gastroenterol Clin N Am. 2003;32:S25\u2013S35.","journal-title":"Gastroenterol Clin N Am"},{"key":"2297_CR2","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s00228-008-0538-y","volume":"64","author":"S Shi","year":"2008","unstructured":"Shi S, Klotz U. Proton pump inhibitors: an update of their clinical use and pharmacokinetics. Eur J Clin Pharmacol. 2008;64:935\u2013951.","journal-title":"Eur J Clin Pharmacol"},{"key":"2297_CR3","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1365-2125.2005.02566.x","volume":"61","author":"M Miura","year":"2006","unstructured":"Miura M, Kagaya H, Tada H, et al. Enantioselective disposition of rabeprazole in relation to CYP2C19 genotypes. Br J Clin Pharmacol. 2006;61:315\u2013320.","journal-title":"Br J Clin Pharmacol"},{"key":"2297_CR4","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s00228-004-0809-1","volume":"60","author":"M Miura","year":"2004","unstructured":"Miura M, Tada H, Yasui-Furukori N, et al. Pharmacokinetic differences between the enantiomers of lansoprazole and its metabolite, 5-hydroxylansoprazole, in relation to CYP2C19 genotypes. Eur J Clin Pharmacol. 2004;60:623\u2013628.","journal-title":"Eur J Clin Pharmacol"},{"key":"2297_CR5","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/(SICI)1520-636X(1997)9:1<17::AID-CHIR4>3.0.CO;2-D","volume":"9","author":"M Tanaka","year":"1997","unstructured":"Tanaka M, Yamazaki H, Hakusui H, et al. Differential stereoselective pharmacokinetics of pantoprazole, a proton pump inhibitor in extensive and poor metabolizers of pantoprazole\u2014a preliminary study. Chirality. 1997;9:17\u201321.","journal-title":"Chirality"},{"key":"2297_CR6","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1067\/mcp.2001.113723","volume":"69","author":"M Tanaka","year":"2001","unstructured":"Tanaka M, Ohkubo T, Otani K, et al. Stereoselective pharmacokinetics of pantoprazole, a proton pump inhibitor, in extensive and poor metabolizers of S-mephenytoin. Clin Pharmacol Ther. 2001;69:108\u2013113.","journal-title":"Clin Pharmacol Ther"},{"key":"2297_CR7","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1007\/s11095-005-6807-x","volume":"22","author":"Z Xie","year":"2005","unstructured":"Xie Z, Zhang Y, Xu H, et al. Pharmacokinetic differences between pantoprazole enantiomers in rats. Pharm Res. 2005;22:1678\u20131684.","journal-title":"Pharm Res"},{"key":"2297_CR8","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0009-9236(97)90081-3","volume":"62","author":"M Tanaka","year":"1997","unstructured":"Tanaka M, Ohkubo T, Otani K, et al. Metabolic disposition of pantoprazole, a proton pump inhibitor, in relation to S-mephenytoin 4\u2032-hydroxylation phenotype and genotype. Clin Pharmacol Ther. 1997;62:619\u2013628.","journal-title":"Clin Pharmacol Ther"},{"key":"2297_CR9","doi-asserted-by":"crossref","first-page":"263","DOI":"10.2165\/00044011-200828050-00001","volume":"28","author":"T Andersson","year":"2008","unstructured":"Andersson T, Weidolf L. Stereoselective disposition of proton pump inhibitors. Clin Drug Investig. 2008;28:263\u2013279.","journal-title":"Clin Drug Investig"},{"key":"2297_CR10","doi-asserted-by":"crossref","first-page":"4100","DOI":"10.3748\/wjg.v13.i30.4100","volume":"13","author":"V Pai","year":"2007","unstructured":"Pai V, Pai N. Randomized, double-blind, comparative study of dexrabeprazole 10\u00a0mg versus rabeprazole 20\u00a0mg in the treatment of gastroesophageal reflux disease. World J Gastroenterol. 2007;13:4100\u20134102.","journal-title":"World J Gastroenterol"},{"key":"2297_CR11","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1211\/0022357056361","volume":"57","author":"H Cao","year":"2005","unstructured":"Cao H, Wang MW, Sun LX, et al. Pharmacodynamic comparison of pantoprazole enantiomers: inhibition of acid-related lesions and acid secretion in rats and guinea-pigs. J Pharm Pharmacol. 2005;57:923\u2013927.","journal-title":"J Pharm Pharmacol"},{"key":"2297_CR12","doi-asserted-by":"crossref","first-page":"6017","DOI":"10.3748\/wjg.v12.i37.6017","volume":"12","author":"VG Pai","year":"2006","unstructured":"Pai VG, Pai NV, Thacker HP, et al. Comparative clinical trial of S-pantoprazole versus racemic pantoprazole in the treatment of gastro-esophageal reflux disease. World J Gastroenterol. 2006;12:6017\u20136020.","journal-title":"World J Gastroenterol"},{"key":"2297_CR13","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1046\/j.1365-2036.2001.01087.x","volume":"15","author":"T Andersson","year":"2001","unstructured":"Andersson T, R\u00f6hss K, Bredberg E, et al. Pharmacokinetics and pharmacodynamics of esomeprazole, the S-isomer of omeprazole. Aliment Pharmacol Ther. 2001;15:1563\u20131569.","journal-title":"Aliment Pharmacol Ther"},{"key":"2297_CR14","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1097\/00007691-199404000-00018","volume":"16","author":"T Ishizaki","year":"1994","unstructured":"Ishizaki T, Sohn DR, Kobayashi K, et al. Interethnic differences inomeprazole metabolism in the two S-mephenytoin hydroxylation phenotypes studied in Caucasians and Orientals. Ther Drug Monit. 1994;16:214\u2013215.","journal-title":"Ther Drug Monit"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-012-2297-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-012-2297-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-012-2297-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T19:45:03Z","timestamp":1559245503000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-012-2297-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,8]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["2297"],"URL":"https:\/\/doi.org\/10.1007\/s10620-012-2297-y","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,8]]}}}